Affinity Data by PubMed id=1316968

PubMed code 1316968

Found 21 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Potassium-transporting ATPase alpha chain 1/subunit beta (Rattus norvegicus)	BDBM50000672 (6-Methoxy-4-methyl-1-o-tolyl-1H-pyrrolo[3,2-c]quin...) Show SMILES COc1cccc2c3n(ccc3c(C)nc12)-c1ccccc1C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Inhibition of rat isolated gastric(H+/K+)-ATPase.				J Med Chem 35: 1845-52 (1992) BindingDB Entry DOI: 10.7270/Q2SQ8ZB3
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Rattus norvegicus)	BDBM50000668 (2-(6-Methyl-1-o-tolyl-1H-pyrrolo[3,2-c]quinolin-4-...) Show SMILES Cc1ccccc1-n1ccc2c(NCCO)nc3c(C)cccc3c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Inhibition of rat isolated gastric(H+/K+)-ATPase.				J Med Chem 35: 1845-52 (1992) BindingDB Entry DOI: 10.7270/Q2SQ8ZB3
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Rattus norvegicus)	BDBM50000675 (CHEMBL54511 \| Methyl-(6-methyl-1-o-tolyl-2,3-dihyd...) Show SMILES CNc1nc2c(C)cccc2c2N(CCc12)c1ccccc1C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Inhibition of rat isolated gastric(H+/K+)-ATPase.				J Med Chem 35: 1845-52 (1992) BindingDB Entry DOI: 10.7270/Q2SQ8ZB3
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Rattus norvegicus)	BDBM50000673 (6-Methyl-1-o-tolyl-2,3-dihydro-1H-pyrrolo[3,2-c]qu...) Show SMILES Cc1ccccc1N1CCc2c1c1cccc(C)c1nc2N Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Inhibition of rat isolated gastric(H+/K+)-ATPase.				J Med Chem 35: 1845-52 (1992) BindingDB Entry DOI: 10.7270/Q2SQ8ZB3
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Rattus norvegicus)	BDBM50000677 (4-(6-Methyl-1-o-tolyl-1H-pyrrolo[3,2-c]quinolin-4-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Inhibition of rat isolated gastric(H+/K+)-ATPase.				J Med Chem 35: 1845-52 (1992) BindingDB Entry DOI: 10.7270/Q2SQ8ZB3
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Rattus norvegicus)	BDBM50000684 ((6-Methoxy-1-o-tolyl-2,3-dihydro-1H-pyrrolo[3,2-c]...) Show SMILES CNc1nc2c(OC)cccc2c2N(CCc12)c1ccccc1C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Inhibition of rat isolated gastric(H+/K+)-ATPase.				J Med Chem 35: 1845-52 (1992) BindingDB Entry DOI: 10.7270/Q2SQ8ZB3
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Rattus norvegicus)	BDBM50000682 (CHEMBL292179 \| [1-(4-Methoxy-2-methyl-phenyl)-6-me...) Show SMILES CNc1nc2c(C)cccc2c2N(CCc12)c1ccc(OC)cc1C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Inhibition of rat isolated gastric(H+/K+)-ATPase.				J Med Chem 35: 1845-52 (1992) BindingDB Entry DOI: 10.7270/Q2SQ8ZB3
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Rattus norvegicus)	BDBM50000666 (2-(6-Methoxy-1-o-tolyl-2,3-dihydro-1H-pyrrolo[3,2-...) Show SMILES COc1cccc2c3N(CCc3c(NCCO)nc12)c1ccccc1C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Inhibition of rat isolated gastric(H+/K+)-ATPase.				J Med Chem 35: 1845-52 (1992) BindingDB Entry DOI: 10.7270/Q2SQ8ZB3
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Rattus norvegicus)	BDBM50000680 (CHEMBL52811 \| Methyl-(6-methyl-1-o-tolyl-1H-pyrrol...) Show SMILES CNc1nc2c(C)cccc2c2n(ccc12)-c1ccccc1C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Inhibition of rat isolated gastric(H+/K+)-ATPase.				J Med Chem 35: 1845-52 (1992) BindingDB Entry DOI: 10.7270/Q2SQ8ZB3
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Rattus norvegicus)	BDBM50000667 (3-(6-Methyl-1-o-tolyl-1H-pyrrolo[3,2-c]quinolin-4-...) Show SMILES Cc1ccccc1-n1ccc2c(NCCCO)nc3c(C)cccc3c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Inhibition of rat isolated gastric(H+/K+)-ATPase.				J Med Chem 35: 1845-52 (1992) BindingDB Entry DOI: 10.7270/Q2SQ8ZB3
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Rattus norvegicus)	BDBM50000679 (6-Methoxy-1-(2-methoxy-phenyl)-2,3-dihydro-1H-pyrr...) Show SMILES COc1ccccc1N1CCc2c1c1cccc(OC)c1nc2N Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Inhibition of rat isolated gastric(H+/K+)-ATPase.				J Med Chem 35: 1845-52 (1992) BindingDB Entry DOI: 10.7270/Q2SQ8ZB3
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Rattus norvegicus)	BDBM50000670 (8-Methoxy-4-o-tolylamino-quinoline-2-carboxylic ac...) Show SMILES CCOC(=O)c1cc(Nc2ccccc2C)c2cccc(OC)c2n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Inhibition of rat isolated gastric(H+/K+)-ATPase.				J Med Chem 35: 1845-52 (1992) BindingDB Entry DOI: 10.7270/Q2SQ8ZB3
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Rattus norvegicus)	BDBM50000685 (6-Methyl-1-o-tolyl-2,3-dihydro-1H-pyrrolo[3,2-c]qu...) Show SMILES Cc1ccccc1N1CCc2cnc3c(C)cccc3c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Inhibition of rat isolated gastric(H+/K+)-ATPase.				J Med Chem 35: 1845-52 (1992) BindingDB Entry DOI: 10.7270/Q2SQ8ZB3
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Rattus norvegicus)	BDBM50000681 (CHEMBL54813 \| Dimethyl-(6-methyl-1-o-tolyl-2,3-dih...) Show SMILES CN(C)c1nc2c(C)cccc2c2N(CCc12)c1ccccc1C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Inhibition of rat isolated gastric(H+/K+)-ATPase.				J Med Chem 35: 1845-52 (1992) BindingDB Entry DOI: 10.7270/Q2SQ8ZB3
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Rattus norvegicus)	BDBM50000686 ((8-Methyl-1-o-tolyl-2,3-dihydro-1H-pyrrolo[2,3-b]q...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Inhibition of rat isolated gastric(H+/K+)-ATPase.				J Med Chem 35: 1845-52 (1992) BindingDB Entry DOI: 10.7270/Q2SQ8ZB3
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Rattus norvegicus)	BDBM50000671 ((1-o-Tolyl-2,3-dihydro-1H-pyrrolo[3,2-c]quinolin-4...) Show SMILES Cc1ccccc1N1CCc2c1c1ccccc1nc2CO Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Inhibition of rat isolated gastric(H+/K+)-ATPase.				J Med Chem 35: 1845-52 (1992) BindingDB Entry DOI: 10.7270/Q2SQ8ZB3
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Rattus norvegicus)	BDBM50000669 (6-Methoxy-1-(2-methoxy-phenyl)-2,3-dihydro-1H-pyrr...) Show SMILES COc1ccccc1N1CCc2cnc3c(OC)cccc3c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Inhibition of rat isolated gastric(H+/K+)-ATPase.				J Med Chem 35: 1845-52 (1992) BindingDB Entry DOI: 10.7270/Q2SQ8ZB3
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Rattus norvegicus)	BDBM50000676 (1-Methyl-3-(6-methyl-1-o-tolyl-2,3-dihydro-1H-pyrr...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Inhibition of rat isolated gastric(H+/K+)-ATPase.				J Med Chem 35: 1845-52 (1992) BindingDB Entry DOI: 10.7270/Q2SQ8ZB3
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Rattus norvegicus)	BDBM50000678 ((6-Methyl-1-o-tolyl-2,3-dihydro-1H-pyrrolo[3,2-c]q...) Show SMILES Cc1ccccc1N1CCc2c1c1cccc(C)c1nc2NC(N)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Inhibition of rat isolated gastric(H+/K+)-ATPase.				J Med Chem 35: 1845-52 (1992) BindingDB Entry DOI: 10.7270/Q2SQ8ZB3
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Rattus norvegicus)	BDBM50000674 (4-Chloro-6-methoxy-1-(2-methoxy-phenyl)-2,3-dihydr...) Show SMILES COc1ccccc1N1CCc2c1c1cccc(OC)c1nc2Cl Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description The compound was evaluated for the inhibition of gastric H+/K+ ATPase				J Med Chem 35: 1845-52 (1992) BindingDB Entry DOI: 10.7270/Q2SQ8ZB3
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Rattus norvegicus)	BDBM50000683 (6-Methoxy-1-(2-methoxy-phenyl)-2,3-dihydro-1H-pyrr...) Show SMILES COc1ccccc1N1CCc2c1c1cccc(OC)c1[nH]c2=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.34E+4	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Inhibition of rat isolated gastric(H+/K+)-ATPase.				J Med Chem 35: 1845-52 (1992) BindingDB Entry DOI: 10.7270/Q2SQ8ZB3
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%