Affinity Data by PubMed id=1354263

PubMed code 1354263

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 1A/1B/1D/1F (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate \| 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of human erythrocyte carbonic anhydrase II				J Med Chem 35: 3045-9 (1992) BindingDB Entry DOI: 10.7270/Q2JD4XDS
Universit£ di Bari Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 1A/1B/1D/1F (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)	BDBM21393 (7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...) Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1 Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of human erythrocyte carbonic anhydrase II				J Med Chem 35: 3045-9 (1992) BindingDB Entry DOI: 10.7270/Q2JD4XDS
Universit£ di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010617 ((-)-3-(1-Propyl-piperidin-3-yl)-phenol \| (S)-3-(1-...) Show SMILES CCCN1CCC[C@H](C1)c1cccc(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Ability to displace [3H]spiroperidol, from dopamine receptor D2 specific binding sites of rat striatal membranes				J Med Chem 35: 3045-9 (1992) BindingDB Entry DOI: 10.7270/Q2JD4XDS
Universit£ di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A/1B/1D/1F (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)	BDBM50002127 (2-(3-Methoxy-phenyl)-4-propyl-morpholine \| 2-(3-me...) Show SMILES CCCN1CCOC(C1)c1cccc(OC)c1 Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of human erythrocyte carbonic anhydrase II				J Med Chem 35: 3045-9 (1992) BindingDB Entry DOI: 10.7270/Q2JD4XDS
Universit£ di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A/1B/1D/1F (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)	BDBM50229868 (CHEMBL102288) Show SMILES CCCN1CCOC(C1)c1ccccc1OC Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of human erythrocyte carbonic anhydrase II				J Med Chem 35: 3045-9 (1992) BindingDB Entry DOI: 10.7270/Q2JD4XDS
Universit£ di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A/1B/1D/1F (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)	BDBM50229869 (CHEMBL432595) Show SMILES CCCN1CCOC(C1)c1ccccc1Cl Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of human erythrocyte carbonic anhydrase II				J Med Chem 35: 3045-9 (1992) BindingDB Entry DOI: 10.7270/Q2JD4XDS
Universit£ di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A/1B/1D/1F (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)	BDBM50002129 (2-(3-Chloro-phenyl)-4-propyl-morpholine \| 2-(3-chl...) Show SMILES CCCN1CCOC(C1)c1cccc(Cl)c1 Show InChI	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of human erythrocyte carbonic anhydrase II				J Med Chem 35: 3045-9 (1992) BindingDB Entry DOI: 10.7270/Q2JD4XDS
Universit£ di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002126 (2-(1-Propyl-piperidin-3-yl)-phenol \| CHEMBL104987) Show SMILES CCCN1CCCC(C1)c1ccccc1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Ability to displace [3H]spiroperidol, from dopamine receptor D2 specific binding sites of rat striatal membranes				J Med Chem 35: 3045-9 (1992) BindingDB Entry DOI: 10.7270/Q2JD4XDS
Universit£ di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002130 (3-(2-Methoxy-phenyl)-1-propyl-piperidine \| 3-(2-Me...) Show SMILES CCCN1CCCC(C1)c1ccccc1OC Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Ability to displace [3H]spiroperidol, from dopamine receptor D2 specific binding sites of rat striatal membranes				J Med Chem 35: 3045-9 (1992) BindingDB Entry DOI: 10.7270/Q2JD4XDS
Universit£ di Bari Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%