Affinity Data by PubMed id=1433194

PubMed code 1433194

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50003252 (4-(4-Morpholin-4-ylmethyl-benzenesulfonyl)-thiophe...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase II				J Med Chem 35: 3822-31 (1992) BindingDB Entry DOI: 10.7270/Q2ZG6SV4
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50003246 (4-(3-Dimethylaminomethyl-4-hydroxy-benzenesulfonyl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase II				J Med Chem 35: 3822-31 (1992) BindingDB Entry DOI: 10.7270/Q2ZG6SV4
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50003246 (4-(3-Dimethylaminomethyl-4-hydroxy-benzenesulfonyl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Compound was tested in vitro for binding affinity against human carbonic anhydrase II; (ki*10e-9)				J Med Chem 35: 3822-31 (1992) BindingDB Entry DOI: 10.7270/Q2ZG6SV4
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50003247 (4-(4-Morpholin-4-ylmethyl-benzoyl)-thiophene-2-sul...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Compound was tested in vitro for binding affinity against human carbonic anhydrase II; (ki*10e-9)				J Med Chem 35: 3822-31 (1992) BindingDB Entry DOI: 10.7270/Q2ZG6SV4
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50003244 (4-(3-Diethylaminomethyl-4-hydroxy-benzenesulfonyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase II				J Med Chem 35: 3822-31 (1992) BindingDB Entry DOI: 10.7270/Q2ZG6SV4
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50003245 (4-[4-(Isobutylamino-methyl)-benzenesulfonyl]-thiop...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Compound was tested in vitro for binding affinity against human carbonic anhydrase II; (ki*10e-9)				J Med Chem 35: 3822-31 (1992) BindingDB Entry DOI: 10.7270/Q2ZG6SV4
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50003251 (4-(4-Hydroxy-benzenesulfonyl)-thiophene-2-sulfonic...) Show SMILES NS(=O)(=O)c1cc(cs1)S(=O)(=O)c1ccc(O)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase II				J Med Chem 35: 3822-31 (1992) BindingDB Entry DOI: 10.7270/Q2ZG6SV4
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50003243 (4-(3-Morpholin-4-ylmethyl-benzoyl)-thiophene-2-sul...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase II				J Med Chem 35: 3822-31 (1992) BindingDB Entry DOI: 10.7270/Q2ZG6SV4
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50003242 (4-[3-(Isobutylamino-methyl)-benzoyl]-thiophene-2-s...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase II				J Med Chem 35: 3822-31 (1992) BindingDB Entry DOI: 10.7270/Q2ZG6SV4
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50003248 (4-(3-Diethylaminomethyl-4-hydroxy-benzoyl)-thiophe...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Compound was tested in vitro for binding affinity against human carbonic anhydrase II; (ki*10e-9)				J Med Chem 35: 3822-31 (1992) BindingDB Entry DOI: 10.7270/Q2ZG6SV4
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50003249 (4-[2-(Isobutylamino-methyl)-benzenesulfonyl]-thiop...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase II				J Med Chem 35: 3822-31 (1992) BindingDB Entry DOI: 10.7270/Q2ZG6SV4
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50003250 (4-(3-Dimethylaminomethyl-4-hydroxy-benzoyl)-thioph...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Compound was tested in vitro for binding affinity against human carbonic anhydrase II; (ki*10e-9)				J Med Chem 35: 3822-31 (1992) BindingDB Entry DOI: 10.7270/Q2ZG6SV4
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%