Affinity Data by PubMed id=14561099

PubMed code 14561099

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50134782 (6-amino-9-[(Z)-(2-{[(1,2,3,3-tetrahydroxy-1,2,3-tr...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University School of Medicine Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Reverse transcriptase wild-type (RT wt)				J Med Chem 46: 4799-802 (2003) Article DOI: 10.1021/jm030048y BindingDB Entry DOI: 10.7270/Q2D50NQB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50164644 (2',3'-Dideoxyadenosine Triphosphate (Ddatp) \| 2',3...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University School of Medicine Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase (RT M184V)				J Med Chem 46: 4799-802 (2003) Article DOI: 10.1021/jm030048y BindingDB Entry DOI: 10.7270/Q2D50NQB
					More data for this Ligand-Target Pair				3D Structure (crystal)
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50164644 (2',3'-Dideoxyadenosine Triphosphate (Ddatp) \| 2',3...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University School of Medicine Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Reverse transcriptase wild-type (RT wt)				J Med Chem 46: 4799-802 (2003) Article DOI: 10.1021/jm030048y BindingDB Entry DOI: 10.7270/Q2D50NQB
					More data for this Ligand-Target Pair				3D Structure (crystal)
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50164644 (2',3'-Dideoxyadenosine Triphosphate (Ddatp) \| 2',3...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University School of Medicine Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase (RT M184I)				J Med Chem 46: 4799-802 (2003) Article DOI: 10.1021/jm030048y BindingDB Entry DOI: 10.7270/Q2D50NQB
					More data for this Ligand-Target Pair				3D Structure (crystal)
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50134782 (6-amino-9-[(Z)-(2-{[(1,2,3,3-tetrahydroxy-1,2,3-tr...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University School of Medicine Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase (RT M184V)				J Med Chem 46: 4799-802 (2003) Article DOI: 10.1021/jm030048y BindingDB Entry DOI: 10.7270/Q2D50NQB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50134782 (6-amino-9-[(Z)-(2-{[(1,2,3,3-tetrahydroxy-1,2,3-tr...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University School of Medicine Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase (RT M184I)				J Med Chem 46: 4799-802 (2003) Article DOI: 10.1021/jm030048y BindingDB Entry DOI: 10.7270/Q2D50NQB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50134783 (6-amino-9-[(E)-(2-{[(1,2,3,3-tetrahydroxy-1,2,3-tr...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University School of Medicine Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Reverse transcriptase wild-type (RT wt)				J Med Chem 46: 4799-802 (2003) Article DOI: 10.1021/jm030048y BindingDB Entry DOI: 10.7270/Q2D50NQB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50134783 (6-amino-9-[(E)-(2-{[(1,2,3,3-tetrahydroxy-1,2,3-tr...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University School of Medicine Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase (RT M184V)				J Med Chem 46: 4799-802 (2003) Article DOI: 10.1021/jm030048y BindingDB Entry DOI: 10.7270/Q2D50NQB
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50134783 (6-amino-9-[(E)-(2-{[(1,2,3,3-tetrahydroxy-1,2,3-tr...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University School of Medicine Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase (RT M184I)				J Med Chem 46: 4799-802 (2003) Article DOI: 10.1021/jm030048y BindingDB Entry DOI: 10.7270/Q2D50NQB
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%