Found 74 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Coagulation factor X
(Homo sapiens (Human)) | BDBM50066638
(3-[6-(5-Carbamimidoyl-2-hydroxy-phenoxy)-3,5-diflu...)Show SMILES CN(C)C(=O)c1cccc(Oc2nc(Oc3cc(ccc3O)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C22H20F2N4O4/c1-11-17(23)20(31-14-6-4-5-13(9-14)22(30)28(2)3)27-21(18(11)24)32-16-10-12(19(25)26)7-8-15(16)29/h4-10,29H,1-3H3,(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50066637
(2-(5-Carbamimidoyl-2-hydroxy-phenoxy)-6-[3-(1-meth...)Show SMILES CN1CCN=C1c1cccc(Oc2cc(cc(Oc3cc(ccc3O)C(N)=N)n2)C(O)=O)c1 |c:4| Show InChI InChI=1S/C23H21N5O5/c1-28-8-7-26-22(28)14-3-2-4-16(9-14)32-19-11-15(23(30)31)12-20(27-19)33-18-10-13(21(24)25)5-6-17(18)29/h2-6,9-12,29H,7-8H2,1H3,(H3,24,25)(H,30,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113913
(3-[6-(3-Dimethylamino-phenoxy)-3,5-difluoro-4-meth...)Show SMILES CN(C)c1cccc(Oc2nc(Oc3cc(ccc3O)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C21H20F2N4O3/c1-11-17(22)20(29-14-6-4-5-13(10-14)27(2)3)26-21(18(11)23)30-16-9-12(19(24)25)7-8-15(16)28/h4-10,28H,1-3H3,(H3,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113894
(2-(5-Carbamimidoyl-2-hydroxy-phenoxy)-6-(3-carbami...)Show SMILES NC(=N)c1cccc(Oc2cc(cc(Oc3cc(ccc3O)C(N)=N)n2)C(O)=O)c1 Show InChI InChI=1S/C20H17N5O5/c21-18(22)10-2-1-3-13(6-10)29-16-8-12(20(27)28)9-17(25-16)30-15-7-11(19(23)24)4-5-14(15)26/h1-9,26H,(H3,21,22)(H3,23,24)(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113925
(2-(5-Carbamimidoyl-2-hydroxy-phenoxy)-6-[3-(2-meth...)Show SMILES Cc1nccn1-c1cccc(Oc2cc(cc(Oc3cc(ccc3O)C(N)=N)n2)C(O)=O)c1 Show InChI InChI=1S/C23H19N5O5/c1-13-26-7-8-28(13)16-3-2-4-17(12-16)32-20-10-15(23(30)31)11-21(27-20)33-19-9-14(22(24)25)5-6-18(19)29/h2-12,29H,1H3,(H3,24,25)(H,30,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113883
(2-(5-Carbamimidoyl-2-hydroxy-phenoxy)-6-[3-(1,4-di...)Show SMILES Cc1cn(C)c(n1)-c1cccc(Oc2cc(cc(Oc3cc(ccc3O)C(N)=N)n2)C(O)=O)c1 Show InChI InChI=1S/C24H21N5O5/c1-13-12-29(2)23(27-13)15-4-3-5-17(8-15)33-20-10-16(24(31)32)11-21(28-20)34-19-9-14(22(25)26)6-7-18(19)30/h3-12,30H,1-2H3,(H3,25,26)(H,31,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50066636
(2-(5-Carbamimidoyl-2-hydroxy-phenoxy)-6-[3-(1-meth...)Show SMILES Cn1ccnc1-c1cccc(Oc2cc(cc(Oc3cc(ccc3O)C(N)=N)n2)C(O)=O)c1 Show InChI InChI=1S/C23H19N5O5/c1-28-8-7-26-22(28)14-3-2-4-16(9-14)32-19-11-15(23(30)31)12-20(27-19)33-18-10-13(21(24)25)5-6-17(18)29/h2-12,29H,1H3,(H3,24,25)(H,30,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113909
(2-(5-Carbamimidoyl-2-hydroxy-phenoxy)-6-[3-(4-meth...)Show SMILES Cc1cn(cn1)-c1cccc(Oc2cc(cc(Oc3cc(ccc3O)C(N)=N)n2)C(O)=O)c1 Show InChI InChI=1S/C23H19N5O5/c1-13-11-28(12-26-13)16-3-2-4-17(10-16)32-20-8-15(23(30)31)9-21(27-20)33-19-7-14(22(24)25)5-6-18(19)29/h2-12,29H,1H3,(H3,24,25)(H,30,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50066627
(3-[6-(2-Amino-5-carbamimidoyl-phenoxy)-3,5-difluor...)Show SMILES CN(C)C(=O)c1cccc(Oc2nc(Oc3cc(ccc3N)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C22H21F2N5O3/c1-11-17(23)20(31-14-6-4-5-13(9-14)22(30)29(2)3)28-21(18(11)24)32-16-10-12(19(26)27)7-8-15(16)25/h4-10H,25H2,1-3H3,(H3,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113865
(3-[6-(5-Carbamimidoyl-2,3-dihydroxy-phenoxy)-3,5-d...)Show SMILES CN(C)C(=O)c1cccc(Oc2nc(Oc3cc(cc(O)c3O)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C22H20F2N4O5/c1-10-16(23)20(32-13-6-4-5-11(7-13)22(31)28(2)3)27-21(17(10)24)33-15-9-12(19(25)26)8-14(29)18(15)30/h4-9,29-30H,1-3H3,(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50066617
(2-(5-Carbamimidoyl-2-hydroxy-phenoxy)-6-(3-imidazo...)Show SMILES NC(=N)c1ccc(O)c(Oc2cc(cc(Oc3cccc(c3)-n3ccnc3)n2)C(O)=O)c1 Show InChI InChI=1S/C22H17N5O5/c23-21(24)13-4-5-17(28)18(8-13)32-20-10-14(22(29)30)9-19(26-20)31-16-3-1-2-15(11-16)27-7-6-25-12-27/h1-12,28H,(H3,23,24)(H,29,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50066620
(2,6-Bis-(3-carbamimidoyl-phenoxy)-isonicotinic aci...)Show SMILES NC(=N)c1cccc(Oc2cc(cc(Oc3cccc(c3)C(N)=N)n2)C(O)=O)c1 Show InChI InChI=1S/C20H17N5O4/c21-18(22)11-3-1-5-14(7-11)28-16-9-13(20(26)27)10-17(25-16)29-15-6-2-4-12(8-15)19(23)24/h1-10H,(H3,21,22)(H3,23,24)(H,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 59 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113916
(4-Amino-3-[6-(3-dimethylamino-phenoxy)-3,5-difluor...)Show SMILES CN(C)c1cccc(Oc2nc(Oc3cc(ccc3N)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C21H21F2N5O2/c1-11-17(22)20(29-14-6-4-5-13(10-14)28(2)3)27-21(18(11)23)30-16-9-12(19(25)26)7-8-15(16)24/h4-10H,24H2,1-3H3,(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 64 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50066633
(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)Show SMILES CN(C)C(=O)c1cccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C22H20F2N4O3/c1-12-17(23)20(30-15-8-4-6-13(10-15)19(25)26)27-21(18(12)24)31-16-9-5-7-14(11-16)22(29)28(2)3/h4-11H,1-3H3,(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM17279
(2-(5-carbamimidoyl-2-hydroxyphenoxy)-6-[3-(4,5-dih...)Show SMILES NC(=N)c1ccc(O)c(Oc2cc(cc(Oc3cccc(c3)C3=NCCN3)n2)C(O)=O)c1 |t:23| Show InChI InChI=1S/C22H19N5O5/c23-20(24)12-4-5-16(28)17(9-12)32-19-11-14(22(29)30)10-18(27-19)31-15-3-1-2-13(8-15)21-25-6-7-26-21/h1-5,8-11,28H,6-7H2,(H3,23,24)(H,25,26)(H,29,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| 85 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113920
(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)Show SMILES COc1cc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)cc(c1)C(=O)N(C)C Show InChI InChI=1S/C23H22F2N4O4/c1-12-18(24)21(32-15-7-5-6-13(8-15)20(26)27)28-22(19(12)25)33-17-10-14(23(30)29(2)3)9-16(11-17)31-4/h5-11H,1-4H3,(H3,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113901
(3-[6-(5-Carbamimidoyl-3-hydroxy-2-methoxy-phenoxy)...)Show SMILES COc1c(O)cc(cc1Oc1nc(Oc2cccc(c2)C(=O)N(C)C)c(F)c(C)c1F)C(N)=N Show InChI InChI=1S/C23H22F2N4O5/c1-11-17(24)21(33-14-7-5-6-12(8-14)23(31)29(2)3)28-22(18(11)25)34-16-10-13(20(26)27)9-15(30)19(16)32-4/h5-10,30H,1-4H3,(H3,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113857
(5-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)Show SMILES CN(C)C(=O)c1cc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)cc(c1)C(=O)N(C)C Show InChI InChI=1S/C25H25F2N5O4/c1-13-19(26)22(35-17-8-6-7-14(10-17)21(28)29)30-23(20(13)27)36-18-11-15(24(33)31(2)3)9-16(12-18)25(34)32(4)5/h6-12H,1-5H3,(H3,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50066632
(3-[6-(3-Dimethylamino-phenoxy)-3,5-difluoro-4-meth...)Show SMILES CN(C)c1cccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C21H20F2N4O2/c1-12-17(22)20(28-15-8-4-6-13(10-15)19(24)25)26-21(18(12)23)29-16-9-5-7-14(11-16)27(2)3/h4-11H,1-3H3,(H3,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113867
(3-[6-(5-Carbamimidoyl-2,3-dimethoxy-phenoxy)-3,5-d...)Show SMILES COc1cc(cc(Oc2nc(Oc3cccc(c3)C(=O)N(C)C)c(F)c(C)c2F)c1OC)C(N)=N Show InChI InChI=1S/C24H24F2N4O5/c1-12-18(25)22(34-15-8-6-7-13(9-15)24(31)30(2)3)29-23(19(12)26)35-17-11-14(21(27)28)10-16(32-4)20(17)33-5/h6-11H,1-5H3,(H3,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113873
(3-{3,5-Difluoro-4-methyl-6-[3-(pyrrolidine-1-carbo...)Show SMILES Cc1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2cccc(c2)C(=O)N2CCCC2)c1F Show InChI InChI=1S/C24H22F2N4O3/c1-14-19(25)22(32-17-8-4-6-15(12-17)21(27)28)29-23(20(14)26)33-18-9-5-7-16(13-18)24(31)30-10-2-3-11-30/h4-9,12-13H,2-3,10-11H2,1H3,(H3,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50066624
(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)Show SMILES Cc1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2cccc(c2)C(N)=O)c1F Show InChI InChI=1S/C20H16F2N4O3/c1-10-15(21)19(28-13-6-2-4-11(8-13)17(23)24)26-20(16(10)22)29-14-7-3-5-12(9-14)18(25)27/h2-9H,1H3,(H3,23,24)(H2,25,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113879
(2-{3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-m...)Show SMILES Cc1c(F)c(Oc2cccc(CC(N)=O)c2)nc(Oc2cccc(c2)C(N)=N)c1F Show InChI InChI=1S/C21H18F2N4O3/c1-11-17(22)20(29-14-6-2-4-12(8-14)9-16(24)28)27-21(18(11)23)30-15-7-3-5-13(10-15)19(25)26/h2-8,10H,9H2,1H3,(H2,24,28)(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113919
(3-[6-(3-Dimethylamino-2-methyl-phenoxy)-3,5-difluo...)Show SMILES CN(C)c1cccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)c1C Show InChI InChI=1S/C22H22F2N4O2/c1-12-16(28(3)4)9-6-10-17(12)30-22-19(24)13(2)18(23)21(27-22)29-15-8-5-7-14(11-15)20(25)26/h5-11H,1-4H3,(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113932
(3-[6-(3-Diethylamino-phenoxy)-3,5-difluoro-4-methy...)Show SMILES CCN(CC)c1cccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C23H24F2N4O2/c1-4-29(5-2)16-9-7-11-18(13-16)31-23-20(25)14(3)19(24)22(28-23)30-17-10-6-8-15(12-17)21(26)27/h6-13H,4-5H2,1-3H3,(H3,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113895
(2-{3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-m...)Show SMILES CN(C)C(=O)Cc1cccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C23H22F2N4O3/c1-13-19(24)22(31-16-8-4-6-14(10-16)11-18(30)29(2)3)28-23(20(13)25)32-17-9-5-7-15(12-17)21(26)27/h4-10,12H,11H2,1-3H3,(H3,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113908
(3-[6-(4-Chloro-3-dimethylamino-phenoxy)-3,5-difluo...)Show SMILES CN(C)c1cc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)ccc1Cl Show InChI InChI=1S/C21H19ClF2N4O2/c1-11-17(23)20(29-13-6-4-5-12(9-13)19(25)26)27-21(18(11)24)30-14-7-8-15(22)16(10-14)28(2)3/h4-10H,1-3H3,(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113877
(3-[6-(3-Ethylamino-phenoxy)-3,5-difluoro-4-methyl-...)Show SMILES CCNc1cccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C21H20F2N4O2/c1-3-26-14-7-5-9-16(11-14)29-21-18(23)12(2)17(22)20(27-21)28-15-8-4-6-13(10-15)19(24)25/h4-11,26H,3H2,1-2H3,(H3,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 530 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113863
(3-[3,5-Difluoro-6-(3-isopropoxy-phenoxy)-4-methyl-...)Show SMILES CC(C)Oc1cccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C22H21F2N3O3/c1-12(2)28-16-8-5-9-17(11-16)30-22-19(24)13(3)18(23)21(27-22)29-15-7-4-6-14(10-15)20(25)26/h4-12H,1-3H3,(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 620 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50136946
(3-[3,5-Difluoro-4-methyl-6-(3-piperidin-1-yl-pheno...)Show SMILES Cc1c(F)c(Oc2cccc(c2)N2CCCCC2)nc(Oc2cccc(c2)C(N)=N)c1F Show InChI InChI=1S/C24H24F2N4O2/c1-15-20(25)23(31-18-9-5-7-16(13-18)22(27)28)29-24(21(15)26)32-19-10-6-8-17(14-19)30-11-3-2-4-12-30/h5-10,13-14H,2-4,11-12H2,1H3,(H3,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 650 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113912
(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)Show SMILES CCN(CC)C(=O)c1cccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C24H24F2N4O3/c1-4-30(5-2)24(31)16-9-7-11-18(13-16)33-23-20(26)14(3)19(25)22(29-23)32-17-10-6-8-15(12-17)21(27)28/h6-13H,4-5H2,1-3H3,(H3,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 690 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50066630
(3-[6-(5-Carbamimidoyl-2-methoxy-phenoxy)-3,5-diflu...)Show SMILES COc1ccc(cc1Oc1nc(Oc2cccc(c2)C(=O)N(C)C)c(F)c(C)c1F)C(N)=N Show InChI InChI=1S/C23H22F2N4O4/c1-12-18(24)21(32-15-7-5-6-14(10-15)23(30)29(2)3)28-22(19(12)25)33-17-11-13(20(26)27)8-9-16(17)31-4/h5-11H,1-4H3,(H3,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 720 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113874
(CHEMBL80119 | {3-[6-(3-Carbamimidoyl-phenoxy)-3,5-...)Show SMILES CCOC(=O)Cc1cccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C23H21F2N3O4/c1-3-30-18(29)11-14-6-4-8-16(10-14)31-22-19(24)13(2)20(25)23(28-22)32-17-9-5-7-15(12-17)21(26)27/h4-10,12H,3,11H2,1-2H3,(H3,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 810 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50136945
(2-(5-Carbamimidoyl-2-hydroxy-phenoxy)-6-[3-(1,4,4-...)Show SMILES CN1CC(C)(C)N=C1c1cccc(Oc2cc(cc(Oc3cc(ccc3O)C(N)=N)n2)C(O)=O)c1 |c:6| Show InChI InChI=1S/C25H25N5O5/c1-25(2)13-30(3)23(29-25)15-5-4-6-17(9-15)34-20-11-16(24(32)33)12-21(28-20)35-19-10-14(22(26)27)7-8-18(19)31/h4-12,31H,13H2,1-3H3,(H3,26,27)(H,32,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 810 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113924
(3-{3,5-Difluoro-4-methyl-6-[3-(piperidine-1-carbon...)Show SMILES Cc1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2cccc(c2)C(=O)N2CCCCC2)c1F Show InChI InChI=1S/C25H24F2N4O3/c1-15-20(26)23(33-18-9-5-7-16(13-18)22(28)29)30-24(21(15)27)34-19-10-6-8-17(14-19)25(32)31-11-3-2-4-12-31/h5-10,13-14H,2-4,11-12H2,1H3,(H3,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 820 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50066643
(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)Show SMILES CNC(=O)c1cccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C21H18F2N4O3/c1-11-16(22)20(29-14-7-3-5-12(9-14)18(24)25)27-21(17(11)23)30-15-8-4-6-13(10-15)19(28)26-2/h3-10H,1-2H3,(H3,24,25)(H,26,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113903
(3-[6-(3-Dimethylamino-phenoxy)-3,5-difluoro-4-meth...)Show SMILES CN(C)c1cccc(Oc2nc(Oc3cc(ccc3C)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C22H22F2N4O2/c1-12-8-9-14(20(25)26)10-17(12)30-22-19(24)13(2)18(23)21(27-22)29-16-7-5-6-15(11-16)28(3)4/h5-11H,1-4H3,(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113860
(3-[3,5-Difluoro-6-(3-hydroxymethyl-phenoxy)-4-meth...)Show SMILES Cc1c(F)c(Oc2cccc(CO)c2)nc(Oc2cccc(c2)C(N)=N)c1F Show InChI InChI=1S/C20H17F2N3O3/c1-11-16(21)19(27-14-6-2-4-12(8-14)10-26)25-20(17(11)22)28-15-7-3-5-13(9-15)18(23)24/h2-9,26H,10H2,1H3,(H3,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113891
(3-{3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-m...)Show SMILES CN(C)C(=O)CCc1cccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C24H24F2N4O3/c1-14-20(25)23(32-17-8-4-6-15(12-17)10-11-19(31)30(2)3)29-24(21(14)26)33-18-9-5-7-16(13-18)22(27)28/h4-9,12-13H,10-11H2,1-3H3,(H3,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113889
(3-[3,5-Difluoro-6-(3-methoxy-phenoxy)-4-methyl-pyr...)Show SMILES COc1cccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C20H17F2N3O3/c1-11-16(21)19(27-14-7-3-5-12(9-14)18(23)24)25-20(17(11)22)28-15-8-4-6-13(10-15)26-2/h3-10H,1-2H3,(H3,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113878
(5-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)Show SMILES COc1ccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)cc1C(=O)N(C)C Show InChI InChI=1S/C23H22F2N4O4/c1-12-18(24)21(32-14-7-5-6-13(10-14)20(26)27)28-22(19(12)25)33-15-8-9-17(31-4)16(11-15)23(30)29(2)3/h5-11H,1-4H3,(H3,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113910
(3-[6-(3-Dimethylamino-phenoxy)-3,5-difluoro-4-meth...)Show SMILES COc1ccc(cc1Oc1nc(Oc2cccc(c2)N(C)C)c(F)c(C)c1F)C(N)=N Show InChI InChI=1S/C22H22F2N4O3/c1-12-18(23)21(30-15-7-5-6-14(11-15)28(2)3)27-22(19(12)24)31-17-10-13(20(25)26)8-9-16(17)29-4/h5-11H,1-4H3,(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113882
(3-{3,5-Difluoro-4-methyl-6-[3-(morpholine-4-carbon...)Show SMILES Cc1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2cccc(c2)C(=O)N2CCOCC2)c1F Show InChI InChI=1S/C24H22F2N4O4/c1-14-19(25)22(33-17-6-2-4-15(12-17)21(27)28)29-23(20(14)26)34-18-7-3-5-16(13-18)24(31)30-8-10-32-11-9-30/h2-7,12-13H,8-11H2,1H3,(H3,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50136947
(3-{3,5-Difluoro-4-methyl-6-[3-(2-oxo-propyl)-pheno...)Show SMILES CC(=O)Cc1cccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C22H19F2N3O3/c1-12(28)9-14-5-3-7-16(10-14)29-21-18(23)13(2)19(24)22(27-21)30-17-8-4-6-15(11-17)20(25)26/h3-8,10-11H,9H2,1-2H3,(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113917
(3-[3,5-Difluoro-4-methyl-6-(3-trifluoromethyl-phen...)Show SMILES Cc1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2cccc(c2)C(F)(F)F)c1F Show InChI InChI=1S/C20H14F5N3O2/c1-10-15(21)18(29-13-6-2-4-11(8-13)17(26)27)28-19(16(10)22)30-14-7-3-5-12(9-14)20(23,24)25/h2-9H,1H3,(H3,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113931
(3-[6-(3-Chloro-phenoxy)-3,5-difluoro-4-methyl-pyri...)Show SMILES Cc1c(F)c(Oc2cccc(Cl)c2)nc(Oc2cccc(c2)C(N)=N)c1F Show InChI InChI=1S/C19H14ClF2N3O2/c1-10-15(21)18(26-13-6-2-4-11(8-13)17(23)24)25-19(16(10)22)27-14-7-3-5-12(20)9-14/h2-9H,1H3,(H3,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113864
(3-[3,5-Difluoro-4-methyl-6-(3-trifluoromethoxy-phe...)Show SMILES Cc1c(F)c(Oc2cccc(OC(F)(F)F)c2)nc(Oc2cccc(c2)C(N)=N)c1F Show InChI InChI=1S/C20H14F5N3O3/c1-10-15(21)18(29-12-5-2-4-11(8-12)17(26)27)28-19(16(10)22)30-13-6-3-7-14(9-13)31-20(23,24)25/h2-9H,1H3,(H3,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113892
(5-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)Show SMILES CN(C)C(=O)c1cc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)ccc1O Show InChI InChI=1S/C22H20F2N4O4/c1-11-17(23)20(31-13-6-4-5-12(9-13)19(25)26)27-21(18(11)24)32-14-7-8-16(29)15(10-14)22(30)28(2)3/h4-10,29H,1-3H3,(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50136948
(3-{3,5-Difluoro-4-methyl-6-[3-(3-methyl-2-oxo-buty...)Show SMILES CC(C)C(=O)Cc1cccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C24H23F2N3O3/c1-13(2)19(30)11-15-6-4-8-17(10-15)31-23-20(25)14(3)21(26)24(29-23)32-18-9-5-7-16(12-18)22(27)28/h4-10,12-13H,11H2,1-3H3,(H3,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113859
(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)Show SMILES COc1c(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)cccc1C(=O)N(C)C Show InChI InChI=1S/C23H22F2N4O4/c1-12-17(24)21(32-14-8-5-7-13(11-14)20(26)27)28-22(18(12)25)33-16-10-6-9-15(19(16)31-4)23(30)29(2)3/h5-11H,1-4H3,(H3,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113918
(CHEMBL312134 | N-Benzyl-3-[6-(3-carbamimidoyl-phen...)Show SMILES CN(Cc1ccccc1)C(=O)c1cccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C28H24F2N4O3/c1-17-23(29)26(36-21-12-6-10-19(14-21)25(31)32)33-27(24(17)30)37-22-13-7-11-20(15-22)28(35)34(2)16-18-8-4-3-5-9-18/h3-15H,16H2,1-2H3,(H3,31,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113899
(3-[3,5-Difluoro-4-methyl-6-(3-nitro-phenoxy)-pyrid...)Show SMILES Cc1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2cccc(c2)[N+]([O-])=O)c1F Show InChI InChI=1S/C19H14F2N4O4/c1-10-15(20)18(28-13-6-2-4-11(8-13)17(22)23)24-19(16(10)21)29-14-7-3-5-12(9-14)25(26)27/h2-9H,1H3,(H3,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113929
(3-[6-(3-Carbamimidoyl-5-methoxy-phenoxy)-3,5-diflu...)Show SMILES COc1cc(Oc2nc(Oc3cccc(c3)C(=O)N(C)C)c(F)c(C)c2F)cc(c1)C(N)=N Show InChI InChI=1S/C23H22F2N4O4/c1-12-18(24)21(32-15-7-5-6-13(8-15)23(30)29(2)3)28-22(19(12)25)33-17-10-14(20(26)27)9-16(11-17)31-4/h5-11H,1-4H3,(H3,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113933
(3-[3,5-Difluoro-6-(3-fluoro-phenoxy)-4-methyl-pyri...)Show SMILES Cc1c(F)c(Oc2cccc(F)c2)nc(Oc2cccc(c2)C(N)=N)c1F Show InChI InChI=1S/C19H14F3N3O2/c1-10-15(21)18(26-13-6-2-4-11(8-13)17(23)24)25-19(16(10)22)27-14-7-3-5-12(20)9-14/h2-9H,1H3,(H3,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113902
(3-[6-(3-Amino-phenoxy)-3,5-difluoro-4-methyl-pyrid...)Show SMILES Cc1c(F)c(Oc2cccc(N)c2)nc(Oc2cccc(c2)C(N)=N)c1F Show InChI InChI=1S/C19H16F2N4O2/c1-10-15(20)18(26-13-6-2-4-11(8-13)17(23)24)25-19(16(10)21)27-14-7-3-5-12(22)9-14/h2-9H,22H2,1H3,(H3,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113907
(3-[3,5-Difluoro-6-(3-methanesulfonylamino-phenoxy)...)Show SMILES Cc1c(F)c(Oc2cccc(NS(C)(=O)=O)c2)nc(Oc2cccc(c2)C(N)=N)c1F Show InChI InChI=1S/C20H18F2N4O4S/c1-11-16(21)19(29-14-7-3-5-12(9-14)18(23)24)25-20(17(11)22)30-15-8-4-6-13(10-15)26-31(2,27)28/h3-10,26H,1-2H3,(H3,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113898
(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)Show SMILES CN(C)C(=O)c1cccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)c1O Show InChI InChI=1S/C22H20F2N4O4/c1-11-16(23)20(31-13-7-4-6-12(10-13)19(25)26)27-21(17(11)24)32-15-9-5-8-14(18(15)29)22(30)28(2)3/h4-10,29H,1-3H3,(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113868
(3-[6-(3-Dimethylamino-phenoxy)-3,5-difluoro-4-meth...)Show SMILES COc1ccc(C(N)=N)c(OC)c1Oc1nc(Oc2cccc(c2)N(C)C)c(F)c(C)c1F Show InChI InChI=1S/C23H24F2N4O4/c1-12-17(24)22(32-14-8-6-7-13(11-14)29(2)3)28-23(18(12)25)33-20-16(30-4)10-9-15(21(26)27)19(20)31-5/h6-11H,1-5H3,(H3,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined; Inactive |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50066621
(3-(3,5-Difluoro-4-methyl-6-phenoxy-pyridin-2-yloxy...)Show SMILES Cc1c(F)c(Oc2ccccc2)nc(Oc2cccc(c2)C(N)=N)c1F Show InChI InChI=1S/C19H15F2N3O2/c1-11-15(20)18(25-13-7-3-2-4-8-13)24-19(16(11)21)26-14-9-5-6-12(10-14)17(22)23/h2-10H,1H3,(H3,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined; Inactive |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113906
(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)Show SMILES COc1ccc(cc1Oc1nc(Oc2cccc(c2)C(N)=N)c(F)c(C)c1F)C(=O)N(C)C Show InChI InChI=1S/C23H22F2N4O4/c1-12-18(24)21(32-15-7-5-6-13(10-15)20(26)27)28-22(19(12)25)33-17-11-14(23(30)29(2)3)8-9-16(17)31-4/h5-11H,1-4H3,(H3,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined; Inactive |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113928
(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)Show SMILES COc1cc(cc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)c1OC)C(=O)N(C)C Show InChI InChI=1S/C24H24F2N4O5/c1-12-18(25)22(34-15-8-6-7-13(9-15)21(27)28)29-23(19(12)26)35-17-11-14(24(31)30(2)3)10-16(32-4)20(17)33-5/h6-11H,1-5H3,(H3,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined; Inactive |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113897
(3-[6-(5-Dimethylamino-2-methoxy-phenoxy)-3,5-diflu...)Show SMILES COc1ccc(cc1Oc1nc(Oc2cccc(c2)C(N)=N)c(F)c(C)c1F)N(C)C Show InChI InChI=1S/C22H22F2N4O3/c1-12-18(23)21(30-15-7-5-6-13(10-15)20(25)26)27-22(19(12)24)31-17-11-14(28(2)3)8-9-16(17)29-4/h5-11H,1-4H3,(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined; Inactive |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113914
(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)Show SMILES CN(C)C(=O)c1ccc(C)c(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C23H22F2N4O3/c1-12-8-9-15(23(30)29(3)4)11-17(12)32-22-19(25)13(2)18(24)21(28-22)31-16-7-5-6-14(10-16)20(26)27/h5-11H,1-4H3,(H3,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined; Inactive |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113927
(3-{3,5-Difluoro-4-methyl-6-[3-(4-methyl-piperazine...)Show SMILES CN1CCN(CC1)C(=O)c1cccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C25H25F2N5O3/c1-15-20(26)23(34-18-7-3-5-16(13-18)22(28)29)30-24(21(15)27)35-19-8-4-6-17(14-19)25(33)32-11-9-31(2)10-12-32/h3-8,13-14H,9-12H2,1-2H3,(H3,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined; Inactive |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113923
(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)Show SMILES CN(C)C(=O)c1cc(O)cc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C22H20F2N4O4/c1-11-17(23)20(31-15-6-4-5-12(8-15)19(25)26)27-21(18(11)24)32-16-9-13(7-14(29)10-16)22(30)28(2)3/h4-10,29H,1-3H3,(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined; Inactive |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113896
(2-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)Show SMILES CCOC(=O)c1ccc(cc1Oc1nc(Oc2cccc(c2)C(N)=N)c(F)c(C)c1F)N(C)C Show InChI InChI=1S/C24H24F2N4O4/c1-5-32-24(31)17-10-9-15(30(3)4)12-18(17)34-23-20(26)13(2)19(25)22(29-23)33-16-8-6-7-14(11-16)21(27)28/h6-12H,5H2,1-4H3,(H3,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined; Inactive |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113884
(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)Show SMILES CN(C)C(=O)c1ccc(O)c(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C22H20F2N4O4/c1-11-17(23)20(31-14-6-4-5-12(9-14)19(25)26)27-21(18(11)24)32-16-10-13(7-8-15(16)29)22(30)28(2)3/h4-10,29H,1-3H3,(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined; Inactive |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113921
(3-[6-(5-Dimethylamino-2-methyl-phenoxy)-3,5-difluo...)Show SMILES CN(C)c1ccc(C)c(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C22H22F2N4O2/c1-12-8-9-15(28(3)4)11-17(12)30-22-19(24)13(2)18(23)21(27-22)29-16-7-5-6-14(10-16)20(25)26/h5-11H,1-4H3,(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined; Inactive |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113926
(3-[3,5-Difluoro-6-(3-hydroxy-phenoxy)-4-methyl-pyr...)Show SMILES Cc1c(F)c(Oc2cccc(O)c2)nc(Oc2cccc(c2)C(N)=N)c1F Show InChI InChI=1S/C19H15F2N3O3/c1-10-15(20)18(26-13-6-2-4-11(8-13)17(22)23)24-19(16(10)21)27-14-7-3-5-12(25)9-14/h2-9,25H,1H3,(H3,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113869
(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)Show SMILES Cc1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2cccc(c2)C(=O)Nc2ccccc2)c1F Show InChI InChI=1S/C26H20F2N4O3/c1-15-21(27)25(34-19-11-5-7-16(13-19)23(29)30)32-26(22(15)28)35-20-12-6-8-17(14-20)24(33)31-18-9-3-2-4-10-18/h2-14H,1H3,(H3,29,30)(H,31,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined; Inactive |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113900
(3-[6-(3-Carbamimidoyl-2-hydroxy-phenoxy)-3,5-diflu...)Show SMILES CN(C)C(=O)c1cccc(Oc2nc(Oc3cccc(C(N)=N)c3O)c(F)c(C)c2F)c1 Show InChI InChI=1S/C22H20F2N4O4/c1-11-16(23)20(31-13-7-4-6-12(10-13)22(30)28(2)3)27-21(17(11)24)32-15-9-5-8-14(18(15)29)19(25)26/h4-10,29H,1-3H3,(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined; Inactive |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113893
(3-[6-(3-Carbamimidoyl-2-hydroxy-5-methoxy-phenoxy)...)Show SMILES COc1cc(Oc2nc(Oc3cccc(c3)C(=O)N(C)C)c(F)c(C)c2F)c(O)c(c1)C(N)=N Show InChI InChI=1S/C23H22F2N4O5/c1-11-17(24)21(33-13-7-5-6-12(8-13)23(31)29(2)3)28-22(18(11)25)34-16-10-14(32-4)9-15(19(16)30)20(26)27/h5-10,30H,1-4H3,(H3,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined; Inactive |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113880
(3-[6-(3-Carbamimidoyl-phenoxy)-3,5-difluoro-4-meth...)Show SMILES CCOC(=O)c1cccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C22H19F2N3O4/c1-3-29-22(28)14-7-5-9-16(11-14)31-21-18(24)12(2)17(23)20(27-21)30-15-8-4-6-13(10-15)19(25)26/h4-11H,3H2,1-2H3,(H3,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 5.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50113904
(CHEMBL82149 | N-{3-[6-(3-Carbamimidoyl-phenoxy)-3,...)Show SMILES CC(=O)Nc1cccc(Oc2nc(Oc3cccc(c3)C(N)=N)c(F)c(C)c2F)c1 Show InChI InChI=1S/C21H18F2N4O3/c1-11-17(22)20(29-15-7-3-5-13(9-15)19(24)25)27-21(18(11)23)30-16-8-4-6-14(10-16)26-12(2)28/h3-10H,1-2H3,(H3,24,25)(H,26,28) | PDB
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Reactome pathway
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PubMed
| 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University
Curated by ChEMBL
| Assay Description
Inhibition of human Coagulation factor X was determined |
J Med Chem 46: 5691-9 (2003)
Article DOI: 10.1021/jm030288d
BindingDB Entry DOI: 10.7270/Q23J3CCP |
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Ligand-Target Pair | |
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