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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sodium/hydrogen exchanger 1 (Homo sapiens (Human)) | BDBM50104856 (CHEMBL51363 | N-[(1R,3S)-3-(3,5-Dichloro-phenyl)-2...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform. | Bioorg Med Chem Lett 14: 177-80 (2003) BindingDB Entry DOI: 10.7270/Q2NC60MN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium/hydrogen exchanger 1 (Homo sapiens (Human)) | BDBM50137552 (5-[(1R,3S)-3-(3,5-Dichloro-phenyl)-2,2-dimethyl-cy...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform. | Bioorg Med Chem Lett 14: 177-80 (2003) BindingDB Entry DOI: 10.7270/Q2NC60MN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium/hydrogen exchanger 1 (Homo sapiens (Human)) | BDBM50104844 (BMS-284640 | CHEMBL51879 | N-[(1R,3R)-3-(2,3-Dihyd...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform. | Bioorg Med Chem Lett 14: 177-80 (2003) BindingDB Entry DOI: 10.7270/Q2NC60MN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium/hydrogen exchanger 1 (Homo sapiens (Human)) | BDBM50104842 (CHEMBL297962 | N-[(1R,3S)-3-(3-Chloro-phenyl)-2,2-...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform. | Bioorg Med Chem Lett 14: 177-80 (2003) BindingDB Entry DOI: 10.7270/Q2NC60MN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium/hydrogen exchanger 1 (Homo sapiens (Human)) | BDBM50137560 (5-[(1R,3S)-3-(3-Chloro-phenyl)-2,2-dimethyl-cyclop...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform. | Bioorg Med Chem Lett 14: 177-80 (2003) BindingDB Entry DOI: 10.7270/Q2NC60MN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium/hydrogen exchanger 1 (Homo sapiens (Human)) | BDBM50137557 (5-[(1R,3S)-3-(3,5-Dichloro-phenyl)-2,2-dimethyl-cy...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform. | Bioorg Med Chem Lett 14: 177-80 (2003) BindingDB Entry DOI: 10.7270/Q2NC60MN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium/hydrogen exchanger 1 (Homo sapiens (Human)) | BDBM50137551 (5-[(1R,3S)-3-(3-Chloro-phenyl)-2,2-dimethyl-cyclop...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform. | Bioorg Med Chem Lett 14: 177-80 (2003) BindingDB Entry DOI: 10.7270/Q2NC60MN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium/hydrogen exchanger 1 (Homo sapiens (Human)) | BDBM50137550 (5-[(1R,3S)-3-(3,5-Dichloro-phenyl)-2,2-dimethyl-cy...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 950 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform. | Bioorg Med Chem Lett 14: 177-80 (2003) BindingDB Entry DOI: 10.7270/Q2NC60MN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium/hydrogen exchanger 1 (Homo sapiens (Human)) | BDBM50137555 (5-[(1R,3R)-3-(2,3-Dihydro-benzofuran-4-yl)-2,2-dim...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform. | Bioorg Med Chem Lett 14: 177-80 (2003) BindingDB Entry DOI: 10.7270/Q2NC60MN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium/hydrogen exchanger 1 (Homo sapiens (Human)) | BDBM50137545 (6-[(1R,3S)-3-(3,5-Dichloro-phenyl)-2,2-dimethyl-cy...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform. | Bioorg Med Chem Lett 14: 177-80 (2003) BindingDB Entry DOI: 10.7270/Q2NC60MN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium/hydrogen exchanger 1 (Homo sapiens (Human)) | BDBM50137556 (5-[(1R,3R)-3-(2,3-Dihydro-benzofuran-4-yl)-2,2-dim...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform. | Bioorg Med Chem Lett 14: 177-80 (2003) BindingDB Entry DOI: 10.7270/Q2NC60MN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium/hydrogen exchanger 1 (Homo sapiens (Human)) | BDBM50137549 (5-[(1R,3S)-3-(3,5-Dichloro-phenyl)-2,2-dimethyl-cy...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform. | Bioorg Med Chem Lett 14: 177-80 (2003) BindingDB Entry DOI: 10.7270/Q2NC60MN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium/hydrogen exchanger 1 (Homo sapiens (Human)) | BDBM50137548 (1-[(1R,3S)-3-(3-Chloro-phenyl)-2,2-dimethyl-cyclop...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 4.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform. | Bioorg Med Chem Lett 14: 177-80 (2003) BindingDB Entry DOI: 10.7270/Q2NC60MN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium/hydrogen exchanger 1 (Homo sapiens (Human)) | BDBM50137554 (5-[(1R,3S)-3-(3-Chloro-phenyl)-2,2-dimethyl-cyclop...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform. | Bioorg Med Chem Lett 14: 177-80 (2003) BindingDB Entry DOI: 10.7270/Q2NC60MN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium/hydrogen exchanger 1 (Homo sapiens (Human)) | BDBM50137547 (1-[(1R,3S)-3-(2,3-Dihydro-benzofuran-4-yl)-2,2-dim...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform. | Bioorg Med Chem Lett 14: 177-80 (2003) BindingDB Entry DOI: 10.7270/Q2NC60MN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium/hydrogen exchanger 1 (Homo sapiens (Human)) | BDBM50137558 (5-[(1R,3R)-3-(2,3-Dihydro-benzofuran-4-yl)-2,2-dim...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform. | Bioorg Med Chem Lett 14: 177-80 (2003) BindingDB Entry DOI: 10.7270/Q2NC60MN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium/hydrogen exchanger 1 (Homo sapiens (Human)) | BDBM50137553 (5-[(1R,3R)-3-(2,3-Dihydro-benzofuran-4-yl)-2,2-dim...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform. | Bioorg Med Chem Lett 14: 177-80 (2003) BindingDB Entry DOI: 10.7270/Q2NC60MN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium/hydrogen exchanger 1 (Homo sapiens (Human)) | BDBM50137546 (5-[(1R,3R)-3-(2,3-Dihydro-benzofuran-4-yl)-2,2-dim...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform. | Bioorg Med Chem Lett 14: 177-80 (2003) BindingDB Entry DOI: 10.7270/Q2NC60MN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium/hydrogen exchanger 1 (Homo sapiens (Human)) | BDBM50137544 (1-[(1R,3S)-3-(3,5-Dichloro-phenyl)-2,2-dimethyl-cy...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform. | Bioorg Med Chem Lett 14: 177-80 (2003) BindingDB Entry DOI: 10.7270/Q2NC60MN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium/hydrogen exchanger 1 (Homo sapiens (Human)) | BDBM50137543 (5-[(1R,3R)-3-(2,3-Dihydro-benzofuran-4-yl)-2,2-dim...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform. | Bioorg Med Chem Lett 14: 177-80 (2003) BindingDB Entry DOI: 10.7270/Q2NC60MN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium/hydrogen exchanger 1 (Homo sapiens (Human)) | BDBM50137559 (5-[(1R,3S)-3-(3,5-Dichloro-phenyl)-2,2-dimethyl-cy...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform. | Bioorg Med Chem Lett 14: 177-80 (2003) BindingDB Entry DOI: 10.7270/Q2NC60MN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
