Affinity Data by PubMed id=1469686

PubMed code 1469686

Found 53 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Acetylcholinesterase (Mus musculus (mouse))	BDBM9409 (CHEMBL299708 \| N-[2-(1-benzylpiperidin-4-yl)ethyl]...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.560	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004000 ((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.690	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004016 (CHEMBL138107 \| CHEMBL544159 \| N-(2-(2-(1-benzylpip...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004007 (2-[2-(1-Benzyl-piperidin-4-yl)-ethyl]-1,3-dioxo-2,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004001 (5-Benzoyl-2-[2-(1-benzyl-piperidin-4-yl)-ethyl]-is...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004035 (CHEMBL433678 \| N-(2-(2-(1-benzylpiperidin-4-yl)eth...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004018 (3-(2-(1-benzylpiperidin-4-yl)ethyl)quinazoline-2,4...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50003999 (3-(2-(1-benzylpiperidin-4-yl)ethyl)-7-chloroquinaz...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50003996 (CHEMBL126354 \| N-(2-(1-benzylpiperidin-4-yl)ethyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004011 (2-(2-(1-benzylpiperidin-4-yl)ethyl)-5-methoxyisoin...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Rattus norvegicus (rat))	BDBM50004000 ((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration of the compound against butyrylcholinesterase (BuChE) obtained from rat plasma				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50003998 (5-Amino-2-[2-(1-benzyl-piperidin-4-yl)-ethyl]-isoi...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.80	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004009 (2-(2-(1-benzylpiperidin-4-yl)ethyl)-4-nitroisoindo...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004015 (4-Amino-2-[2-(1-benzyl-piperidin-4-yl)-ethyl]-isoi...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004013 (6-(2-(1-benzylpiperidin-4-yl)ethyl)-5H-pyrrolo[3,4...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004040 (2-(2-(1-benzylpiperidin-4-yl)ethyl)-5-nitroisoindo...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004033 (3-(2-(1-benzylpiperidin-4-yl)ethyl)-3,4-dihydroqui...) Show SMILES O=C1Nc2ccccc2CN1CCC1CCN(Cc2ccccc2)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004026 (2-(2-(1-benzylpiperidin-4-yl)ethyl)-1,2-dihydroiso...) Show SMILES O=C1Cc2ccccc2CN1CCC1CCN(Cc2ccccc2)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004037 (CHEMBL140737 \| N-(2-(1-benzylpiperidin-4-yl)ethyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004012 (2-(2-(1-benzylpiperidin-4-yl)ethyl)isoquinoline-1,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004020 (2-(2-(1-benzylpiperidin-4-yl)ethyl)isoindoline-1,3...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM9408 ((2E)-but-2-enedioic acid; N-[2-(1-benzylpiperidin-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004017 (CHEMBL127527 \| N-(2-(1-benzylpiperidin-4-yl)ethyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004027 (CHEMBL340672 \| N-(2-(1-benzylpiperidin-4-yl)ethyl)...) Show SMILES CC(=O)N(CCC1CCN(Cc2ccccc2)CC1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004036 (CHEMBL340621 \| N-(2-(1-benzylpiperidin-4-yl)ethyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004028 (CHEMBL141167 \| N-(2-(1-benzylpiperidin-4-yl)ethyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Rattus norvegicus (rat))	BDBM8961 (1,2,3,4-tetrahydro-9-acridinamine \| 1,2,3,4-tetrah...) Show SMILES Nc1c2CCCCc2nc2ccccc12 Show InChI	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration of the compound against Butyrylcholinesterase obtained from rat plasma				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM8961 (1,2,3,4-tetrahydro-9-acridinamine \| 1,2,3,4-tetrah...) Show SMILES Nc1c2CCCCc2nc2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004022 (2-(2-(1-benzylpiperidin-4-yl)ethyl)isoindolin-1-on...) Show SMILES O=C1N(CCC2CCN(Cc3ccccc3)CC2)Cc2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004030 (CHEMBL141352 \| N-(2-(1-benzylpiperidin-4-yl)ethyl)...) Show SMILES CC(=O)N(CCC1CCN(Cc2ccccc2)CC1)c1ccncc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	108	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM9405 (CHEMBL56470 \| N-[2-(1-Benzyl-piperidin-4-yl)-ethyl...) Show SMILES CN(CCC1CCN(Cc2ccccc2)CC1)C(=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004002 (CHEMBL340609 \| N-(2-(1-benzylpiperidin-4-yl)ethyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	205	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004041 (2-(2-(1-(4-chlorobenzyl)piperidin-4-yl)ethyl)-5-ni...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004014 (1-(2-(1-benzylpiperidin-4-yl)ethyl)piperidin-2-one...) Show SMILES O=C1CCCCN1CCC1CCN(Cc2ccccc2)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004034 (CHEMBL141622 \| N-(2-(2-(1-benzylpiperidin-4-yl)eth...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004042 (2-(2-(1-(4-methoxybenzyl)piperidin-4-yl)ethyl)-5-n...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM9385 (1-Benzyl-4-[2-(N-benzoylamino)ethyl]piperidine Hyd...) Show SMILES O=C(NCCC1CCN(Cc2ccccc2)CC1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004006 (CHEMBL141873 \| N-(2-(1-benzylpiperidin-4-yl)ethyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004021 (CHEMBL125578 \| N-(2-(1-benzylpiperidin-4-yl)ethyl)...) Show SMILES CN(CCC1CCN(Cc2ccccc2)CC1)C(C)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50003997 (CHEMBL141801 \| N-(2-(1-benzylpiperidin-4-yl)ethyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004008 (3-(2-(1-benzylpiperidin-4-yl)ethyl)-2,3-dihydroqui...) Show SMILES O=C1N(CCC2CCN(Cc3ccccc3)CC2)CNc2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004005 (CHEMBL141853 \| N-(2-(1-benzylpiperidin-4-yl)ethyl)...) Show SMILES CCC(=O)N(CCC1CCN(Cc2ccccc2)CC1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004003 (2-(2-(1-benzylpiperidin-4-yl)ethyl)-3,4-dihydroiso...) Show SMILES O=C1N(CCC2CCN(Cc3ccccc3)CC2)CCc2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004038 (2-(2-(1-benzylpiperidin-4-yl)ethyl)isoquinolin-1(2...) Show SMILES O=c1n(CCC2CCN(Cc3ccccc3)CC2)ccc2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004032 (3-(2-(1-benzylpiperidin-4-yl)ethyl)quinazolin-4(3H...) Show SMILES O=c1n(CCC2CCN(Cc3ccccc3)CC2)cnc2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004029 (2-(2-(1-benzylpiperidin-4-yl)ethyl)-1,2,3,4-tetrah...) Show SMILES C(CN1CCc2ccccc2C1)C1CCN(Cc2ccccc2)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004010 (2-((1-benzylpiperidin-4-yl)methyl)-5-nitroisoindol...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004023 (2-(2-(1-methylpiperidin-4-yl)ethyl)-5-nitroisoindo...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004019 (CHEMBL140769 \| Cyclohexanecarboxylic acid [2-(1-be...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Rattus norvegicus (rat))	BDBM9409 (CHEMBL299708 \| N-[2-(1-benzylpiperidin-4-yl)ethyl]...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration of the compound against Butyrylcholinesterase obtained from rat plasma				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004024 (CHEMBL140936 \| N-(2-(1-benzylpiperidin-4-yl)ethyl)...) Show SMILES CCN(CCC1CCN(Cc2ccccc2)CC1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50004031 (2-(1-Benzyl-piperidin-4-yl)-5-nitro-isoindole-1,3-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration against acetylcholinesterase (AChE) obtained from mouse brain homogenate.				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Rattus norvegicus (rat))	BDBM50004016 (CHEMBL138107 \| CHEMBL544159 \| N-(2-(2-(1-benzylpip...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory concentration of the compound against Butyrylcholinesterase obtained from rat plasma				J Med Chem 35: 4542-8 (1993) BindingDB Entry DOI: 10.7270/Q25M64P8
Eisai Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%