Found 58 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM19149
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
PDB
PubMed
| n/a | n/a | 73 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 2 (HDAC2) activity of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM19149
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 6 (HDAC6) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase
(Homo sapiens (Human)) | BDBM19149
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase (HDAC)of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50138412
(2-[5-(Formyl-hydroxy-amino)-pentyl]-N,N'-di-quinol...)Show SMILES ON(CCCCCC(C(=O)Nc1cnc2ccccc2c1)C(=O)Nc1cnc2ccccc2c1)C=O Show InChI InChI=1S/C27H27N5O4/c33-18-32(36)13-7-1-2-10-23(26(34)30-21-14-19-8-3-5-11-24(19)28-16-21)27(35)31-22-15-20-9-4-6-12-25(20)29-17-22/h3-6,8-9,11-12,14-18,23,36H,1-2,7,10,13H2,(H,30,34)(H,31,35) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 1 (HDAC1) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50138416
(2-[5-(Formyl-hydroxy-amino)-pentyl]-N,N'-di-quinol...)Show SMILES ON(CCCCCC(C(=O)Nc1ccc2ncccc2c1)C(=O)Nc1ccc2ncccc2c1)C=O Show InChI InChI=1S/C27H27N5O4/c33-18-32(36)15-3-1-2-8-23(26(34)30-21-9-11-24-19(16-21)6-4-13-28-24)27(35)31-22-10-12-25-20(17-22)7-5-14-29-25/h4-7,9-14,16-18,23,36H,1-3,8,15H2,(H,30,34)(H,31,35) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 1 (HDAC1) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50138412
(2-[5-(Formyl-hydroxy-amino)-pentyl]-N,N'-di-quinol...)Show SMILES ON(CCCCCC(C(=O)Nc1cnc2ccccc2c1)C(=O)Nc1cnc2ccccc2c1)C=O Show InChI InChI=1S/C27H27N5O4/c33-18-32(36)13-7-1-2-10-23(26(34)30-21-14-19-8-3-5-11-24(19)28-16-21)27(35)31-22-15-20-9-4-6-12-25(20)29-17-22/h3-6,8-9,11-12,14-18,23,36H,1-2,7,10,13H2,(H,30,34)(H,31,35) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 2 (HDAC2) activity of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50138416
(2-[5-(Formyl-hydroxy-amino)-pentyl]-N,N'-di-quinol...)Show SMILES ON(CCCCCC(C(=O)Nc1ccc2ncccc2c1)C(=O)Nc1ccc2ncccc2c1)C=O Show InChI InChI=1S/C27H27N5O4/c33-18-32(36)15-3-1-2-8-23(26(34)30-21-9-11-24-19(16-21)6-4-13-28-24)27(35)31-22-10-12-25-20(17-22)7-5-14-29-25/h4-7,9-14,16-18,23,36H,1-3,8,15H2,(H,30,34)(H,31,35) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 2 (HDAC2) activity of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM19149
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
MMDB
PDB
PubMed
| n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 8 (HDAC8) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM19149
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
PDB
PubMed
| n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 1 (HDAC1) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50138415
(CHEMBL343717 | Naphthalene-2-carboxylic acid [5-(f...)Show InChI InChI=1S/C17H20N2O3/c20-13-19(22)11-5-1-4-10-18-17(21)16-9-8-14-6-2-3-7-15(14)12-16/h2-3,6-9,12-13,22H,1,4-5,10-11H2,(H,18,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 6 (HDAC6) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50138416
(2-[5-(Formyl-hydroxy-amino)-pentyl]-N,N'-di-quinol...)Show SMILES ON(CCCCCC(C(=O)Nc1ccc2ncccc2c1)C(=O)Nc1ccc2ncccc2c1)C=O Show InChI InChI=1S/C27H27N5O4/c33-18-32(36)15-3-1-2-8-23(26(34)30-21-9-11-24-19(16-21)6-4-13-28-24)27(35)31-22-10-12-25-20(17-22)7-5-14-29-25/h4-7,9-14,16-18,23,36H,1-3,8,15H2,(H,30,34)(H,31,35) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 620 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 6 (HDAC6) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50138419
(8-(Formyl-hydroxy-amino)-octanoic acid naphthalen-...)Show InChI InChI=1S/C19H24N2O3/c22-15-21(24)14-7-3-1-2-4-13-19(23)20-18-12-8-10-16-9-5-6-11-17(16)18/h5-6,8-12,15,24H,1-4,7,13-14H2,(H,20,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 650 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 8 (HDAC8) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50138412
(2-[5-(Formyl-hydroxy-amino)-pentyl]-N,N'-di-quinol...)Show SMILES ON(CCCCCC(C(=O)Nc1cnc2ccccc2c1)C(=O)Nc1cnc2ccccc2c1)C=O Show InChI InChI=1S/C27H27N5O4/c33-18-32(36)13-7-1-2-10-23(26(34)30-21-14-19-8-3-5-11-24(19)28-16-21)27(35)31-22-15-20-9-4-6-12-25(20)29-17-22/h3-6,8-9,11-12,14-18,23,36H,1-2,7,10,13H2,(H,30,34)(H,31,35) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 690 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 8 (HDAC8) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase
(Homo sapiens (Human)) | BDBM50138416
(2-[5-(Formyl-hydroxy-amino)-pentyl]-N,N'-di-quinol...)Show SMILES ON(CCCCCC(C(=O)Nc1ccc2ncccc2c1)C(=O)Nc1ccc2ncccc2c1)C=O Show InChI InChI=1S/C27H27N5O4/c33-18-32(36)15-3-1-2-8-23(26(34)30-21-9-11-24-19(16-21)6-4-13-28-24)27(35)31-22-10-12-25-20(17-22)7-5-14-29-25/h4-7,9-14,16-18,23,36H,1-3,8,15H2,(H,30,34)(H,31,35) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase (HDAC)of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50138422
(8-(Formyl-hydroxy-amino)-octanoic acid naphthalen-...)Show InChI InChI=1S/C19H24N2O3/c22-15-21(24)13-7-3-1-2-4-10-19(23)20-18-12-11-16-8-5-6-9-17(16)14-18/h5-6,8-9,11-12,14-15,24H,1-4,7,10,13H2,(H,20,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 8 (HDAC8) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50138412
(2-[5-(Formyl-hydroxy-amino)-pentyl]-N,N'-di-quinol...)Show SMILES ON(CCCCCC(C(=O)Nc1cnc2ccccc2c1)C(=O)Nc1cnc2ccccc2c1)C=O Show InChI InChI=1S/C27H27N5O4/c33-18-32(36)13-7-1-2-10-23(26(34)30-21-14-19-8-3-5-11-24(19)28-16-21)27(35)31-22-15-20-9-4-6-12-25(20)29-17-22/h3-6,8-9,11-12,14-18,23,36H,1-2,7,10,13H2,(H,30,34)(H,31,35) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 6 (HDAC6) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50138416
(2-[5-(Formyl-hydroxy-amino)-pentyl]-N,N'-di-quinol...)Show SMILES ON(CCCCCC(C(=O)Nc1ccc2ncccc2c1)C(=O)Nc1ccc2ncccc2c1)C=O Show InChI InChI=1S/C27H27N5O4/c33-18-32(36)15-3-1-2-8-23(26(34)30-21-9-11-24-19(16-21)6-4-13-28-24)27(35)31-22-10-12-25-20(17-22)7-5-14-29-25/h4-7,9-14,16-18,23,36H,1-3,8,15H2,(H,30,34)(H,31,35) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 8 (HDAC8) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50138422
(8-(Formyl-hydroxy-amino)-octanoic acid naphthalen-...)Show InChI InChI=1S/C19H24N2O3/c22-15-21(24)13-7-3-1-2-4-10-19(23)20-18-12-11-16-8-5-6-9-17(16)14-18/h5-6,8-9,11-12,14-15,24H,1-4,7,10,13H2,(H,20,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 810 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 1 (HDAC1) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50138422
(8-(Formyl-hydroxy-amino)-octanoic acid naphthalen-...)Show InChI InChI=1S/C19H24N2O3/c22-15-21(24)13-7-3-1-2-4-10-19(23)20-18-12-11-16-8-5-6-9-17(16)14-18/h5-6,8-9,11-12,14-15,24H,1-4,7,10,13H2,(H,20,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 890 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 2 (HDAC2) activity of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50138422
(8-(Formyl-hydroxy-amino)-octanoic acid naphthalen-...)Show InChI InChI=1S/C19H24N2O3/c22-15-21(24)13-7-3-1-2-4-10-19(23)20-18-12-11-16-8-5-6-9-17(16)14-18/h5-6,8-9,11-12,14-15,24H,1-4,7,10,13H2,(H,20,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 6 (HDAC6) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase
(Homo sapiens (Human)) | BDBM50138412
(2-[5-(Formyl-hydroxy-amino)-pentyl]-N,N'-di-quinol...)Show SMILES ON(CCCCCC(C(=O)Nc1cnc2ccccc2c1)C(=O)Nc1cnc2ccccc2c1)C=O Show InChI InChI=1S/C27H27N5O4/c33-18-32(36)13-7-1-2-10-23(26(34)30-21-14-19-8-3-5-11-24(19)28-16-21)27(35)31-22-15-20-9-4-6-12-25(20)29-17-22/h3-6,8-9,11-12,14-18,23,36H,1-2,7,10,13H2,(H,30,34)(H,31,35) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 970 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase (HDAC)of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50138415
(CHEMBL343717 | Naphthalene-2-carboxylic acid [5-(f...)Show InChI InChI=1S/C17H20N2O3/c20-13-19(22)11-5-1-4-10-18-17(21)16-9-8-14-6-2-3-7-15(14)12-16/h2-3,6-9,12-13,22H,1,4-5,10-11H2,(H,18,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 1 (HDAC1) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50138415
(CHEMBL343717 | Naphthalene-2-carboxylic acid [5-(f...)Show InChI InChI=1S/C17H20N2O3/c20-13-19(22)11-5-1-4-10-18-17(21)16-9-8-14-6-2-3-7-15(14)12-16/h2-3,6-9,12-13,22H,1,4-5,10-11H2,(H,18,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 2 (HDAC2) activity of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50138423
(6-(Formyl-hydroxy-amino)-hexanoic acid phenylamide...)Show InChI InChI=1S/C13H18N2O3/c16-11-15(18)10-6-2-5-9-13(17)14-12-7-3-1-4-8-12/h1,3-4,7-8,11,18H,2,5-6,9-10H2,(H,14,17) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 6 (HDAC6) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50138420
(8-(Formyl-hydroxy-amino)-octanoic acid phenylamide...)Show InChI InChI=1S/C15H22N2O3/c18-13-17(20)12-8-3-1-2-7-11-15(19)16-14-9-5-4-6-10-14/h4-6,9-10,13,20H,1-3,7-8,11-12H2,(H,16,19) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 8 (HDAC8) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair |
3D Structure (docked) |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50138419
(8-(Formyl-hydroxy-amino)-octanoic acid naphthalen-...)Show InChI InChI=1S/C19H24N2O3/c22-15-21(24)14-7-3-1-2-4-13-19(23)20-18-12-8-10-16-9-5-6-11-17(16)18/h5-6,8-12,15,24H,1-4,7,13-14H2,(H,20,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 6 (HDAC6) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase
(Homo sapiens (Human)) | BDBM50138422
(8-(Formyl-hydroxy-amino)-octanoic acid naphthalen-...)Show InChI InChI=1S/C19H24N2O3/c22-15-21(24)13-7-3-1-2-4-10-19(23)20-18-12-11-16-8-5-6-9-17(16)14-18/h5-6,8-9,11-12,14-15,24H,1-4,7,10,13H2,(H,20,23) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase (HDAC)of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50138421
(7-(Formyl-hydroxy-amino)-heptanoic acid phenylamid...)Show InChI InChI=1S/C14H20N2O3/c17-12-16(19)11-7-2-1-6-10-14(18)15-13-8-4-3-5-9-13/h3-5,8-9,12,19H,1-2,6-7,10-11H2,(H,15,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 8 (HDAC8) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50138414
(CHEMBL337584 | N-[5-(Formyl-hydroxy-amino)-pentyl]...)Show InChI InChI=1S/C13H18N2O3/c16-11-15(18)10-6-2-5-9-14-13(17)12-7-3-1-4-8-12/h1,3-4,7-8,11,18H,2,5-6,9-10H2,(H,14,17) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 6 (HDAC6) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase
(Homo sapiens (Human)) | BDBM50138415
(CHEMBL343717 | Naphthalene-2-carboxylic acid [5-(f...)Show InChI InChI=1S/C17H20N2O3/c20-13-19(22)11-5-1-4-10-18-17(21)16-9-8-14-6-2-3-7-15(14)12-16/h2-3,6-9,12-13,22H,1,4-5,10-11H2,(H,18,21) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase (HDAC)of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50138420
(8-(Formyl-hydroxy-amino)-octanoic acid phenylamide...)Show InChI InChI=1S/C15H22N2O3/c18-13-17(20)12-8-3-1-2-7-11-15(19)16-14-9-5-4-6-10-14/h4-6,9-10,13,20H,1-3,7-8,11-12H2,(H,16,19) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 6 (HDAC6) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50138419
(8-(Formyl-hydroxy-amino)-octanoic acid naphthalen-...)Show InChI InChI=1S/C19H24N2O3/c22-15-21(24)14-7-3-1-2-4-13-19(23)20-18-12-8-10-16-9-5-6-11-17(16)18/h5-6,8-12,15,24H,1-4,7,13-14H2,(H,20,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 5.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 1 (HDAC1) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50138419
(8-(Formyl-hydroxy-amino)-octanoic acid naphthalen-...)Show InChI InChI=1S/C19H24N2O3/c22-15-21(24)14-7-3-1-2-4-13-19(23)20-18-12-8-10-16-9-5-6-11-17(16)18/h5-6,8-12,15,24H,1-4,7,13-14H2,(H,20,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 2 (HDAC2) activity of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50138423
(6-(Formyl-hydroxy-amino)-hexanoic acid phenylamide...)Show InChI InChI=1S/C13H18N2O3/c16-11-15(18)10-6-2-5-9-13(17)14-12-7-3-1-4-8-12/h1,3-4,7-8,11,18H,2,5-6,9-10H2,(H,14,17) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 6.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 8 (HDAC8) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50138415
(CHEMBL343717 | Naphthalene-2-carboxylic acid [5-(f...)Show InChI InChI=1S/C17H20N2O3/c20-13-19(22)11-5-1-4-10-18-17(21)16-9-8-14-6-2-3-7-15(14)12-16/h2-3,6-9,12-13,22H,1,4-5,10-11H2,(H,18,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 8 (HDAC8) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50138420
(8-(Formyl-hydroxy-amino)-octanoic acid phenylamide...)Show InChI InChI=1S/C15H22N2O3/c18-13-17(20)12-8-3-1-2-7-11-15(19)16-14-9-5-4-6-10-14/h4-6,9-10,13,20H,1-3,7-8,11-12H2,(H,16,19) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 7.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 2 (HDAC2) activity of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50138413
(CHEMBL141885 | N-[5-(Formyl-hydroxy-amino)-pentyl]...)Show InChI InChI=1S/C15H22N2O3/c18-13-17(20)12-6-2-5-11-16-15(19)10-9-14-7-3-1-4-8-14/h1,3-4,7-8,13,20H,2,5-6,9-12H2,(H,16,19) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 9.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 8 (HDAC8) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50138421
(7-(Formyl-hydroxy-amino)-heptanoic acid phenylamid...)Show InChI InChI=1S/C14H20N2O3/c17-12-16(19)11-7-2-1-6-10-14(18)15-13-8-4-3-5-9-13/h3-5,8-9,12,19H,1-2,6-7,10-11H2,(H,15,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 2 (HDAC2) activity of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50138423
(6-(Formyl-hydroxy-amino)-hexanoic acid phenylamide...)Show InChI InChI=1S/C13H18N2O3/c16-11-15(18)10-6-2-5-9-13(17)14-12-7-3-1-4-8-12/h1,3-4,7-8,11,18H,2,5-6,9-10H2,(H,14,17) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 2 (HDAC2) activity of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50138414
(CHEMBL337584 | N-[5-(Formyl-hydroxy-amino)-pentyl]...)Show InChI InChI=1S/C13H18N2O3/c16-11-15(18)10-6-2-5-9-14-13(17)12-7-3-1-4-8-12/h1,3-4,7-8,11,18H,2,5-6,9-10H2,(H,14,17) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 8 (HDAC8) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50138414
(CHEMBL337584 | N-[5-(Formyl-hydroxy-amino)-pentyl]...)Show InChI InChI=1S/C13H18N2O3/c16-11-15(18)10-6-2-5-9-14-13(17)12-7-3-1-4-8-12/h1,3-4,7-8,11,18H,2,5-6,9-10H2,(H,14,17) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 2 (HDAC2) activity of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50138413
(CHEMBL141885 | N-[5-(Formyl-hydroxy-amino)-pentyl]...)Show InChI InChI=1S/C15H22N2O3/c18-13-17(20)12-6-2-5-11-16-15(19)10-9-14-7-3-1-4-8-14/h1,3-4,7-8,13,20H,2,5-6,9-12H2,(H,16,19) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 6 (HDAC6) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50138414
(CHEMBL337584 | N-[5-(Formyl-hydroxy-amino)-pentyl]...)Show InChI InChI=1S/C13H18N2O3/c16-11-15(18)10-6-2-5-9-14-13(17)12-7-3-1-4-8-12/h1,3-4,7-8,11,18H,2,5-6,9-10H2,(H,14,17) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 1 (HDAC1) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50138413
(CHEMBL141885 | N-[5-(Formyl-hydroxy-amino)-pentyl]...)Show InChI InChI=1S/C15H22N2O3/c18-13-17(20)12-6-2-5-11-16-15(19)10-9-14-7-3-1-4-8-14/h1,3-4,7-8,13,20H,2,5-6,9-12H2,(H,16,19) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 2 (HDAC2) activity of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50138413
(CHEMBL141885 | N-[5-(Formyl-hydroxy-amino)-pentyl]...)Show InChI InChI=1S/C15H22N2O3/c18-13-17(20)12-6-2-5-11-16-15(19)10-9-14-7-3-1-4-8-14/h1,3-4,7-8,13,20H,2,5-6,9-12H2,(H,16,19) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 1 (HDAC1) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase
(Homo sapiens (Human)) | BDBM50138419
(8-(Formyl-hydroxy-amino)-octanoic acid naphthalen-...)Show InChI InChI=1S/C19H24N2O3/c22-15-21(24)14-7-3-1-2-4-13-19(23)20-18-12-8-10-16-9-5-6-11-17(16)18/h5-6,8-12,15,24H,1-4,7,13-14H2,(H,20,23) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase (HDAC)of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50138411
(CHEMBL138090 | methyl 7-anilino-7-oxoheptyl(hydrox...)Show InChI InChI=1S/C15H22N2O4/c1-21-15(19)17(20)12-8-3-2-7-11-14(18)16-13-9-5-4-6-10-13/h4-6,9-10,20H,2-3,7-8,11-12H2,1H3,(H,16,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 2 (HDAC2) activity of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase
(Homo sapiens (Human)) | BDBM50138413
(CHEMBL141885 | N-[5-(Formyl-hydroxy-amino)-pentyl]...)Show InChI InChI=1S/C15H22N2O3/c18-13-17(20)12-6-2-5-11-16-15(19)10-9-14-7-3-1-4-8-14/h1,3-4,7-8,13,20H,2,5-6,9-12H2,(H,16,19) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase (HDAC)of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50138417
(6-(Acetyl-hydroxy-amino)-hexanoic acid phenylamide...)Show InChI InChI=1S/C14H20N2O3/c1-12(17)16(19)11-7-3-6-10-14(18)15-13-8-4-2-5-9-13/h2,4-5,8-9,19H,3,6-7,10-11H2,1H3,(H,15,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 8 (HDAC8) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50138411
(CHEMBL138090 | methyl 7-anilino-7-oxoheptyl(hydrox...)Show InChI InChI=1S/C15H22N2O4/c1-21-15(19)17(20)12-8-3-2-7-11-14(18)16-13-9-5-4-6-10-13/h4-6,9-10,20H,2-3,7-8,11-12H2,1H3,(H,16,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 6 (HDAC6) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50138418
(8-(Acetyl-hydroxy-amino)-octanoic acid phenylamide...)Show InChI InChI=1S/C16H24N2O3/c1-14(19)18(21)13-9-4-2-3-8-12-16(20)17-15-10-6-5-7-11-15/h5-7,10-11,21H,2-4,8-9,12-13H2,1H3,(H,17,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 2 (HDAC2) activity of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50138418
(8-(Acetyl-hydroxy-amino)-octanoic acid phenylamide...)Show InChI InChI=1S/C16H24N2O3/c1-14(19)18(21)13-9-4-2-3-8-12-16(20)17-15-10-6-5-7-11-15/h5-7,10-11,21H,2-4,8-9,12-13H2,1H3,(H,17,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 8 (HDAC8) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase
(Homo sapiens (Human)) | BDBM50138417
(6-(Acetyl-hydroxy-amino)-hexanoic acid phenylamide...)Show InChI InChI=1S/C14H20N2O3/c1-12(17)16(19)11-7-3-6-10-14(18)15-13-8-4-2-5-9-13/h2,4-5,8-9,19H,3,6-7,10-11H2,1H3,(H,15,18) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase (HDAC)of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50138417
(6-(Acetyl-hydroxy-amino)-hexanoic acid phenylamide...)Show InChI InChI=1S/C14H20N2O3/c1-12(17)16(19)11-7-3-6-10-14(18)15-13-8-4-2-5-9-13/h2,4-5,8-9,19H,3,6-7,10-11H2,1H3,(H,15,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 2 (HDAC2) activity of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase
(Homo sapiens (Human)) | BDBM50138414
(CHEMBL337584 | N-[5-(Formyl-hydroxy-amino)-pentyl]...)Show InChI InChI=1S/C13H18N2O3/c16-11-15(18)10-6-2-5-9-14-13(17)12-7-3-1-4-8-12/h1,3-4,7-8,11,18H,2,5-6,9-10H2,(H,14,17) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase (HDAC)of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50138417
(6-(Acetyl-hydroxy-amino)-hexanoic acid phenylamide...)Show InChI InChI=1S/C14H20N2O3/c1-12(17)16(19)11-7-3-6-10-14(18)15-13-8-4-2-5-9-13/h2,4-5,8-9,19H,3,6-7,10-11H2,1H3,(H,15,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 6 (HDAC6) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50138418
(8-(Acetyl-hydroxy-amino)-octanoic acid phenylamide...)Show InChI InChI=1S/C16H24N2O3/c1-14(19)18(21)13-9-4-2-3-8-12-16(20)17-15-10-6-5-7-11-15/h5-7,10-11,21H,2-4,8-9,12-13H2,1H3,(H,17,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 6 (HDAC6) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50138411
(CHEMBL138090 | methyl 7-anilino-7-oxoheptyl(hydrox...)Show InChI InChI=1S/C15H22N2O4/c1-21-15(19)17(20)12-8-3-2-7-11-14(18)16-13-9-5-4-6-10-13/h4-6,9-10,20H,2-3,7-8,11-12H2,1H3,(H,16,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Histone deacetylase 8 (HDAC8) of HeLa nuclear extracts |
Bioorg Med Chem Lett 14: 449-53 (2003)
BindingDB Entry DOI: 10.7270/Q2HH6JH2 |
More data for this
Ligand-Target Pair |
3D Structure (docked) |
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