Affinity Data by PubMed id=14698188

PubMed code 14698188

Found 13 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50138434 (CHEMBL147044 \| N-(6-Guanidino-hexyl)-N-(1-phenethy...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Química Médica Curated by ChEMBL					Assay Description Displacement of [3H]-DAMGO (2 nM ) from opioid receptor mu 1 in human brain				Bioorg Med Chem Lett 14: 491-3 (2003) BindingDB Entry DOI: 10.7270/Q2CR5STS
Instituto de Química Médica Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50008984 (4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...) Show SMILES CCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Química Médica Curated by ChEMBL					Assay Description Displacement of [3H]-DAMGO (2 nM ) from opioid receptor mu 1 in human brain				Bioorg Med Chem Lett 14: 491-3 (2003) BindingDB Entry DOI: 10.7270/Q2CR5STS
Instituto de Química Médica Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase [flavin-containing] A/B (Homo sapiens (Human))	BDBM50138435 (CHEMBL147569 \| N-(12-Guanidino-dodecyl)-N-(1-phene...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Química Médica Curated by ChEMBL					Assay Description Displacement of [3H]-2-BFI (1 nM) from imidazoline receptor I-2 in human brain				Bioorg Med Chem Lett 14: 491-3 (2003) BindingDB Entry DOI: 10.7270/Q2CR5STS
Instituto de Química Médica Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50138433 (CHEMBL147949 \| N-(3-Guanidino-propyl)-N-(1-pheneth...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Química Médica Curated by ChEMBL					Assay Description Displacement of [3H]-DAMGO (2 nM ) from opioid receptor mu 1 in human brain				Bioorg Med Chem Lett 14: 491-3 (2003) BindingDB Entry DOI: 10.7270/Q2CR5STS
Instituto de Química Médica Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Homo sapiens (Human))	BDBM50019848 (2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1...) Show SMILES C1CN=C(N1)C1COc2ccccc2O1 \|c:2\| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Química Médica Curated by ChEMBL					Assay Description Displacement of [3H]-2-BFI (1 nM) from imidazoline receptor I-2 in human brain				Bioorg Med Chem Lett 14: 491-3 (2003) BindingDB Entry DOI: 10.7270/Q2CR5STS
Instituto de Química Médica Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50138436 (CHEMBL146997 \| N-(8-Guanidino-octyl)-N-(1-phenethy...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Química Médica Curated by ChEMBL					Assay Description Displacement of [3H]-DAMGO (2 nM ) from opioid receptor mu 1 in human brain				Bioorg Med Chem Lett 14: 491-3 (2003) BindingDB Entry DOI: 10.7270/Q2CR5STS
Instituto de Química Médica Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Homo sapiens (Human))	BDBM50138436 (CHEMBL146997 \| N-(8-Guanidino-octyl)-N-(1-phenethy...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Química Médica Curated by ChEMBL					Assay Description Displacement of [3H]-2-BFI (1 nM) from imidazoline receptor I-2 in human brain				Bioorg Med Chem Lett 14: 491-3 (2003) BindingDB Entry DOI: 10.7270/Q2CR5STS
Instituto de Química Médica Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Homo sapiens (Human))	BDBM50138434 (CHEMBL147044 \| N-(6-Guanidino-hexyl)-N-(1-phenethy...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PubMed	409	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Química Médica Curated by ChEMBL					Assay Description Displacement of [3H]-2-BFI (1 nM) from imidazoline receptor I-2 in human brain				Bioorg Med Chem Lett 14: 491-3 (2003) BindingDB Entry DOI: 10.7270/Q2CR5STS
Instituto de Química Médica Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50138432 (CHEMBL358089 \| N-(2-Guanidino-ethyl)-N-(1-phenethy...) Show SMILES CCC(=O)N(CCNC(N)=N)C1CCN(CCc2ccccc2)CC1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	433	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Química Médica Curated by ChEMBL					Assay Description Displacement of [3H]-DAMGO (2 nM ) from opioid receptor mu 1 in human brain				Bioorg Med Chem Lett 14: 491-3 (2003) BindingDB Entry DOI: 10.7270/Q2CR5STS
Instituto de Química Médica Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Homo sapiens (Human))	BDBM50138432 (CHEMBL358089 \| N-(2-Guanidino-ethyl)-N-(1-phenethy...) Show SMILES CCC(=O)N(CCNC(N)=N)C1CCN(CCc2ccccc2)CC1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	437	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Química Médica Curated by ChEMBL					Assay Description Displacement of [3H]-2-BFI (1 nM) from imidazoline receptor I-2 in human brain				Bioorg Med Chem Lett 14: 491-3 (2003) BindingDB Entry DOI: 10.7270/Q2CR5STS
Instituto de Química Médica Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50138435 (CHEMBL147569 \| N-(12-Guanidino-dodecyl)-N-(1-phene...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	477	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Química Médica Curated by ChEMBL					Assay Description Displacement of [3H]-DAMGO (2 nM ) from opioid receptor mu 1 in human brain				Bioorg Med Chem Lett 14: 491-3 (2003) BindingDB Entry DOI: 10.7270/Q2CR5STS
Instituto de Química Médica Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Homo sapiens (Human))	BDBM50138433 (CHEMBL147949 \| N-(3-Guanidino-propyl)-N-(1-pheneth...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.92E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Química Médica Curated by ChEMBL					Assay Description Displacement of [3H]-2-BFI (1 nM) from imidazoline receptor I-2 in human brain				Bioorg Med Chem Lett 14: 491-3 (2003) BindingDB Entry DOI: 10.7270/Q2CR5STS
Instituto de Química Médica Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Homo sapiens (Human))	BDBM50008984 (4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...) Show SMILES CCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	5.46E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Química Médica Curated by ChEMBL					Assay Description Displacement of [3H]2-BFI (1 nM) from imidazoline receptor I-2 in human brain				Bioorg Med Chem Lett 14: 491-3 (2003) BindingDB Entry DOI: 10.7270/Q2CR5STS
Instituto de Química Médica Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%