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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Histamine H4 receptor (Rattus norvegicus (rat)) | BDBM22566 (5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet  | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 2.60 | -49.0 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Johnson & Johnson Pharmaceutical | Assay Description The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff. | J Pharmacol Exp Ther 309: 404-13 (2004) Article DOI: 10.1124/jpet.103.061754 BindingDB Entry DOI: 10.7270/Q2VX0DTD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histamine H4 receptor (Homo sapiens (Human)) | BDBM22566 (5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 4.10 | -47.9 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Johnson & Johnson Pharmaceutical | Assay Description The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff. | J Pharmacol Exp Ther 309: 404-13 (2004) Article DOI: 10.1124/jpet.103.061754 BindingDB Entry DOI: 10.7270/Q2VX0DTD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histamine H4 receptor (Mus musculus (mouse)) | BDBM22566 (5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 4.60 | -47.6 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Johnson & Johnson Pharmaceutical | Assay Description The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff. | J Pharmacol Exp Ther 309: 404-13 (2004) Article DOI: 10.1124/jpet.103.061754 BindingDB Entry DOI: 10.7270/Q2VX0DTD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histamine H1 receptor (Cavia porcellus (domestic guinea pig)) | BDBM22566 (5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+3 | >-34.2 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Johnson & Johnson Pharmaceutical | Assay Description The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff. | J Pharmacol Exp Ther 309: 404-13 (2004) Article DOI: 10.1124/jpet.103.061754 BindingDB Entry DOI: 10.7270/Q2VX0DTD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histamine H2 receptor (Cavia porcellus (domestic guinea pig)) | BDBM22566 (5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+3 | >-34.2 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Johnson & Johnson Pharmaceutical | Assay Description The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff. | J Pharmacol Exp Ther 309: 404-13 (2004) Article DOI: 10.1124/jpet.103.061754 BindingDB Entry DOI: 10.7270/Q2VX0DTD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histamine H3 receptor (Rattus norvegicus (rat)) | BDBM22566 (5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 4.70E+3 | -30.4 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Johnson & Johnson Pharmaceutical | Assay Description The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff. | J Pharmacol Exp Ther 309: 404-13 (2004) Article DOI: 10.1124/jpet.103.061754 BindingDB Entry DOI: 10.7270/Q2VX0DTD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histamine H3 receptor (Homo sapiens (Human)) | BDBM22566 (5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 5.13E+3 | -30.2 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Johnson & Johnson Pharmaceutical | Assay Description The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff. | J Pharmacol Exp Ther 309: 404-13 (2004) Article DOI: 10.1124/jpet.103.061754 BindingDB Entry DOI: 10.7270/Q2VX0DTD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histamine H1 receptor (Homo sapiens (Human)) | BDBM22566 (5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | >-28.5 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Johnson & Johnson Pharmaceutical | Assay Description The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff. | J Pharmacol Exp Ther 309: 404-13 (2004) Article DOI: 10.1124/jpet.103.061754 BindingDB Entry DOI: 10.7270/Q2VX0DTD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histamine H1 receptor (Mus musculus (mouse)) | BDBM22566 (5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | >-28.5 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Johnson & Johnson Pharmaceutical | Assay Description The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff. | J Pharmacol Exp Ther 309: 404-13 (2004) Article DOI: 10.1124/jpet.103.061754 BindingDB Entry DOI: 10.7270/Q2VX0DTD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
