Affinity Data by PubMed id=14978359

PubMed code 14978359

Found 25 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Solute carrier family 22 member 8 (Homo sapiens (Human))	BDBM50206509 (4-Dipropylsulfamoyl-benzoic acid \| 4-Dipropylsulfa...) Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	n/a	n/a	4.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in hOAT3-expressing S2 cells				J Pharmacol Sci 94: 197-202 (2004) BindingDB Entry DOI: 10.7270/Q27M0915
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 8 (Rattus norvegicus)	BDBM50206509 (4-Dipropylsulfamoyl-benzoic acid \| 4-Dipropylsulfa...) Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	6.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in rOAT3-expressing S2 cells				J Pharmacol Sci 94: 197-202 (2004) BindingDB Entry DOI: 10.7270/Q27M0915
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 8 (Homo sapiens (Human))	BDBM50344964 (Betamipron \| CHEMBL1231530 \| N-(phenylcarbonyl)-be...) Show SMILES OC(=O)CCNC(=O)c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	9.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in hOAT3-expressing S2 cells				J Pharmacol Sci 94: 197-202 (2004) BindingDB Entry DOI: 10.7270/Q27M0915
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 6 (Homo sapiens (Human))	BDBM50206509 (4-Dipropylsulfamoyl-benzoic acid \| 4-Dipropylsulfa...) Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB PubMed	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of PHA uptake (PHA: 5uM) in hOAT1-expressing S2 cells				J Pharmacol Sci 94: 197-202 (2004) BindingDB Entry DOI: 10.7270/Q27M0915
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Solute carrier family 22 member 8 (Homo sapiens (Human))	BDBM20688 ((3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank PubMed	n/a	n/a	1.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in hOAT3-expressing S2 cells				J Pharmacol Sci 94: 197-202 (2004) BindingDB Entry DOI: 10.7270/Q27M0915
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 8 (Rattus norvegicus)	BDBM20688 ((3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.56E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in rOAT3-expressing S2 cells				J Pharmacol Sci 94: 197-202 (2004) BindingDB Entry DOI: 10.7270/Q27M0915
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 11 (Homo sapiens (Human))	BDBM50206509 (4-Dipropylsulfamoyl-benzoic acid \| 4-Dipropylsulfa...) Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	n/a	n/a	2.54E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in hOAT4-expressing S2 cells				J Pharmacol Sci 94: 197-202 (2004) BindingDB Entry DOI: 10.7270/Q27M0915
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 6 (Homo sapiens (Human))	BDBM50344964 (Betamipron \| CHEMBL1231530 \| N-(phenylcarbonyl)-be...) Show SMILES OC(=O)CCNC(=O)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of PHA uptake (PHA: 5uM) in hOAT1-expressing S2 cells				J Pharmacol Sci 94: 197-202 (2004) BindingDB Entry DOI: 10.7270/Q27M0915
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 8 (Rattus norvegicus)	BDBM50344964 (Betamipron \| CHEMBL1231530 \| N-(phenylcarbonyl)-be...) Show SMILES OC(=O)CCNC(=O)c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	4.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in rOAT3-expressing S2 cells				J Pharmacol Sci 94: 197-202 (2004) BindingDB Entry DOI: 10.7270/Q27M0915
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 8 (Homo sapiens (Human))	BDBM22889 ((Cimetidine) N-Methyl-N''''-[2-(5-methyl-1H-imidaz...) Show SMILES CNC(NC#N)=NCCSCc1[nH]cnc1C \|w:6.6\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in hOAT3-expressing S2 cells				J Pharmacol Sci 94: 197-202 (2004) BindingDB Entry DOI: 10.7270/Q27M0915
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 8 (Rattus norvegicus)	BDBM22889 ((Cimetidine) N-Methyl-N''''-[2-(5-methyl-1H-imidaz...) Show SMILES CNC(NC#N)=NCCSCc1[nH]cnc1C \|w:6.6\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.66E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in rOAT3-expressing S2 cells				J Pharmacol Sci 94: 197-202 (2004) BindingDB Entry DOI: 10.7270/Q27M0915
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 8 (Homo sapiens (Human))	BDBM50367502 (CILASTATIN) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	DrugBank PubMed	n/a	n/a	2.49E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in hOAT3-expressing S2 cells				J Pharmacol Sci 94: 197-202 (2004) BindingDB Entry DOI: 10.7270/Q27M0915
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 7 (Homo sapiens (Human))	BDBM20688 ((3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank PubMed	n/a	n/a	3.52E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of PGF2alpha uptake (PGF2: 50nM) in hOAT2-expressing S2 cells				J Pharmacol Sci 94: 197-202 (2004) BindingDB Entry DOI: 10.7270/Q27M0915
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 6 (Homo sapiens (Human))	BDBM20688 ((3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank PubMed	n/a	n/a	4.08E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of PHA uptake (PHA: 5uM) in hOAT1-expressing S2 cells				J Pharmacol Sci 94: 197-202 (2004) BindingDB Entry DOI: 10.7270/Q27M0915
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 7 (Rattus norvegicus)	BDBM20688 ((3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.49E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of PGF2alpha uptake (PGF2: 50nM) in rOAT2-expressing S2 cells				J Pharmacol Sci 94: 197-202 (2004) BindingDB Entry DOI: 10.7270/Q27M0915
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 11 (Homo sapiens (Human))	BDBM50344964 (Betamipron \| CHEMBL1231530 \| N-(phenylcarbonyl)-be...) Show SMILES OC(=O)CCNC(=O)c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	4.83E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in hOAT4-expressing S2 cells				J Pharmacol Sci 94: 197-202 (2004) BindingDB Entry DOI: 10.7270/Q27M0915
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 6 (Homo sapiens (Human))	BDBM22889 ((Cimetidine) N-Methyl-N''''-[2-(5-methyl-1H-imidaz...) Show SMILES CNC(NC#N)=NCCSCc1[nH]cnc1C \|w:6.6\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.92E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of PHA uptake (PHA: 5uM) in hOAT1-expressing S2 cells				J Pharmacol Sci 94: 197-202 (2004) BindingDB Entry DOI: 10.7270/Q27M0915
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 11 (Homo sapiens (Human))	BDBM20688 ((3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank PubMed	n/a	n/a	5.91E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in hOAT4-expressing S2 cells				J Pharmacol Sci 94: 197-202 (2004) BindingDB Entry DOI: 10.7270/Q27M0915
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 7 (Homo sapiens (Human))	BDBM50206509 (4-Dipropylsulfamoyl-benzoic acid \| 4-Dipropylsulfa...) Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	n/a	n/a	6.68E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of PGF2alpha uptake (PGF2: 50nM) in hOAT2-expressing S2 cells				J Pharmacol Sci 94: 197-202 (2004) BindingDB Entry DOI: 10.7270/Q27M0915
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 8 (Rattus norvegicus)	BDBM50367502 (CILASTATIN) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.42E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in rOAT3-expressing S2 cells				J Pharmacol Sci 94: 197-202 (2004) BindingDB Entry DOI: 10.7270/Q27M0915
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 7 (Rattus norvegicus)	BDBM50206509 (4-Dipropylsulfamoyl-benzoic acid \| 4-Dipropylsulfa...) Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	9.77E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of PGF2alpha uptake (PGF2: 50nM) in rOAT2-expressing S2 cells				J Pharmacol Sci 94: 197-202 (2004) BindingDB Entry DOI: 10.7270/Q27M0915
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 6 (Rattus norvegicus)	BDBM22889 ((Cimetidine) N-Methyl-N''''-[2-(5-methyl-1H-imidaz...) Show SMILES CNC(NC#N)=NCCSCc1[nH]cnc1C \|w:6.6\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of PHA uptake (PHA: 5uM) in rOAT1-expressing S2 cells				J Pharmacol Sci 94: 197-202 (2004) BindingDB Entry DOI: 10.7270/Q27M0915
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 11 (Homo sapiens (Human))	BDBM22889 ((Cimetidine) N-Methyl-N''''-[2-(5-methyl-1H-imidaz...) Show SMILES CNC(NC#N)=NCCSCc1[nH]cnc1C \|w:6.6\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of ES uptake (ES: 50nM) in hOAT4-expressing S2 cells				J Pharmacol Sci 94: 197-202 (2004) BindingDB Entry DOI: 10.7270/Q27M0915
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 6 (Rattus norvegicus)	BDBM50367502 (CILASTATIN) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.39E+6	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of PHA uptake (PHA: 5uM) in rOAT1-expressing S2 cells				J Pharmacol Sci 94: 197-202 (2004) BindingDB Entry DOI: 10.7270/Q27M0915
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier family 22 member 6 (Homo sapiens (Human))	BDBM50367502 (CILASTATIN) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	DrugBank PubMed	n/a	n/a	2.55E+6	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of PHA uptake (PHA: 5uM) in hOAT1-expressing S2 cells				J Pharmacol Sci 94: 197-202 (2004) BindingDB Entry DOI: 10.7270/Q27M0915
Kyorin University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%