Affinity Data by PubMed id=14998325

PubMed code 14998325

Found 15 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone deacetylase 1 (Mus musculus (Mouse))	BDBM19130 ((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL					Assay Description Inhibition of mouse HDAC1				J Med Chem 47: 1351-9 (2004) Article DOI: 10.1021/jm031036f BindingDB Entry DOI: 10.7270/Q2X63MCK
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM19130 ((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...) Show SMILES Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL					Assay Description Inhibition of maize Histone deacetylase 2				J Med Chem 47: 1351-9 (2004) Article DOI: 10.1021/jm031036f BindingDB Entry DOI: 10.7270/Q2X63MCK
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM19130 ((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...) Show SMILES Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL					Assay Description Inhibition of maize histone deacetylase 2				J Med Chem 47: 1351-9 (2004) Article DOI: 10.1021/jm031036f BindingDB Entry DOI: 10.7270/Q2X63MCK
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM19149 (CHEMBL98 \| N-hydroxy-N'-phenyloctanediamide \| SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL					Assay Description Inhibition of maize Histone deacetylase 2				J Med Chem 47: 1351-9 (2004) Article DOI: 10.1021/jm031036f BindingDB Entry DOI: 10.7270/Q2X63MCK
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50140882 ((E)-3-(5-Benzoyl-1-methyl-1H-pyrrol-3-yl)-N-hydrox...) Show SMILES Cn1cc(\C=C\C(=O)NO)cc1C(=O)c1ccccc1 Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL					Assay Description Inhibition of maize Histone deacetylase 2				J Med Chem 47: 1351-9 (2004) Article DOI: 10.1021/jm031036f BindingDB Entry DOI: 10.7270/Q2X63MCK
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50140882 ((E)-3-(5-Benzoyl-1-methyl-1H-pyrrol-3-yl)-N-hydrox...) Show SMILES Cn1cc(\C=C\C(=O)NO)cc1C(=O)c1ccccc1 Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL					Assay Description Inhibition of maize histone deacetylase 2				J Med Chem 47: 1351-9 (2004) Article DOI: 10.1021/jm031036f BindingDB Entry DOI: 10.7270/Q2X63MCK
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM19149 (CHEMBL98 \| N-hydroxy-N'-phenyloctanediamide \| SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL					Assay Description Inhibition of maize histone deacetylase 2				J Med Chem 47: 1351-9 (2004) Article DOI: 10.1021/jm031036f BindingDB Entry DOI: 10.7270/Q2X63MCK
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Mus musculus (Mouse))	BDBM19149 (CHEMBL98 \| N-hydroxy-N'-phenyloctanediamide \| SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL					Assay Description Inhibition of mouse HDAC1				J Med Chem 47: 1351-9 (2004) Article DOI: 10.1021/jm031036f BindingDB Entry DOI: 10.7270/Q2X63MCK
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 1 (Mus musculus (Mouse))	BDBM50140883 ((E)-3-(5-Benzoyl-1-methyl-1H-pyrrol-2-yl)-N-hydrox...) Show SMILES Cn1c(\C=C\C(=O)NO)ccc1C(=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	229	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL					Assay Description Inhibition of mouse HDAC1				J Med Chem 47: 1351-9 (2004) Article DOI: 10.1021/jm031036f BindingDB Entry DOI: 10.7270/Q2X63MCK
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50140883 ((E)-3-(5-Benzoyl-1-methyl-1H-pyrrol-2-yl)-N-hydrox...) Show SMILES Cn1c(\C=C\C(=O)NO)ccc1C(=O)c1ccccc1 Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL					Assay Description Inhibition of maize Histone deacetylase 2				J Med Chem 47: 1351-9 (2004) Article DOI: 10.1021/jm031036f BindingDB Entry DOI: 10.7270/Q2X63MCK
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50140883 ((E)-3-(5-Benzoyl-1-methyl-1H-pyrrol-2-yl)-N-hydrox...) Show SMILES Cn1c(\C=C\C(=O)NO)ccc1C(=O)c1ccccc1 Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL					Assay Description Inhibition of maize histone deacetylase 2				J Med Chem 47: 1351-9 (2004) Article DOI: 10.1021/jm031036f BindingDB Entry DOI: 10.7270/Q2X63MCK
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Mus musculus (Mouse))	BDBM50140882 ((E)-3-(5-Benzoyl-1-methyl-1H-pyrrol-3-yl)-N-hydrox...) Show SMILES Cn1cc(\C=C\C(=O)NO)cc1C(=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	776	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL					Assay Description Inhibition of mouse HDAC1				J Med Chem 47: 1351-9 (2004) Article DOI: 10.1021/jm031036f BindingDB Entry DOI: 10.7270/Q2X63MCK
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50140881 ((E)-3-(4-Benzoyl-1-methyl-1H-pyrrol-3-yl)-N-hydrox...) Show SMILES Cn1cc(\C=C\C(=O)NO)c(c1)C(=O)c1ccccc1 Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL					Assay Description Inhibition of maize histone deacetylase 2				J Med Chem 47: 1351-9 (2004) Article DOI: 10.1021/jm031036f BindingDB Entry DOI: 10.7270/Q2X63MCK
					More data for this Ligand-Target Pair
Histone deacetylase 2b (Zea mays)	BDBM50140881 ((E)-3-(4-Benzoyl-1-methyl-1H-pyrrol-3-yl)-N-hydrox...) Show SMILES Cn1cc(\C=C\C(=O)NO)c(c1)C(=O)c1ccccc1 Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL					Assay Description Inhibition of maize Histone deacetylase 2				J Med Chem 47: 1351-9 (2004) Article DOI: 10.1021/jm031036f BindingDB Entry DOI: 10.7270/Q2X63MCK
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Mus musculus (Mouse))	BDBM50140881 ((E)-3-(4-Benzoyl-1-methyl-1H-pyrrol-3-yl)-N-hydrox...) Show SMILES Cn1cc(\C=C\C(=O)NO)c(c1)C(=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma "La Sapienza" Curated by ChEMBL					Assay Description Inhibition of mouse HDAC1				J Med Chem 47: 1351-9 (2004) Article DOI: 10.1021/jm031036f BindingDB Entry DOI: 10.7270/Q2X63MCK
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%