Affinity Data by PubMed id=1501230

PubMed code 1501230

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50004551 (5-Morpholin-4-ylmethyl-thieno[2,3-b]furan-2-sulfon...) Show SMILES NS(=O)(=O)c1cc2cc(CN3CCOCC3)sc2o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of dansylamide at human carbonic anhydrase II				J Med Chem 35: 3027-33 (1992) BindingDB Entry DOI: 10.7270/Q2GX49H7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50004553 (5-{[Bis-(2-methoxy-ethyl)-amino]-methyl}-thieno[2,...) Show SMILES COCCN(CCOC)Cc1cc2cc(oc2s1)S(N)(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of dansylamide at human carbonic anhydrase II				J Med Chem 35: 3027-33 (1992) BindingDB Entry DOI: 10.7270/Q2GX49H7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50004556 (5-[(2-Fluoro-ethylamino)-methyl]-thieno[2,3-b]fura...) Show SMILES NS(=O)(=O)c1cc2cc(CNCCF)sc2o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of dansylamide at human carbonic anhydrase II				J Med Chem 35: 3027-33 (1992) BindingDB Entry DOI: 10.7270/Q2GX49H7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50004554 (5-{[[2-(2-Methoxy-ethoxy)-ethyl]-(2-methoxy-ethyl)...) Show SMILES COCCOCCN(CCOC)Cc1cc2cc(oc2s1)S(N)(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of dansylamide at human carbonic anhydrase II				J Med Chem 35: 3027-33 (1992) BindingDB Entry DOI: 10.7270/Q2GX49H7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50004552 (5-(Isobutylamino-methyl)-thieno[2,3-b]furan-2-sulf...) Show SMILES CC(C)CNCc1cc2cc(oc2s1)S(N)(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	7.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of dansylamide at human carbonic anhydrase II				J Med Chem 35: 3027-33 (1992) BindingDB Entry DOI: 10.7270/Q2GX49H7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50004555 (5-{[(Pyridin-2-ylmethyl)-amino]-methyl}-thieno[2,3...) Show SMILES NS(=O)(=O)c1cc2cc(CNCc3ccccn3)sc2o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of dansylamide at human carbonic anhydrase II				J Med Chem 35: 3027-33 (1992) BindingDB Entry DOI: 10.7270/Q2GX49H7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50004550 (5-Ethylaminomethyl-thieno[2,3-b]furan-2-sulfonic a...) Show SMILES CCNCc1cc2cc(oc2s1)S(N)(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of dansylamide at human carbonic anhydrase II				J Med Chem 35: 3027-33 (1992) BindingDB Entry DOI: 10.7270/Q2GX49H7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50004557 (5-Methylaminomethyl-thieno[2,3-b]furan-2-sulfonic ...) Show SMILES CNCc1cc2cc(oc2s1)S(N)(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of dansylamide at human carbonic anhydrase II				J Med Chem 35: 3027-33 (1992) BindingDB Entry DOI: 10.7270/Q2GX49H7
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%