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PubMed code 15026035

Compile data set for download or QSAR
Found 1 hit of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated potassium channel subunit Kv7.2


(Mus musculus)
BDBM50142346
PNG
(CHEMBL41078 | N-[4-(5-Chloro-2-hydroxy-benzyl)-2-o...)
Show SMILES Oc1ccc(Cl)cc1Cc1c(NS(=O)(=O)C(F)(F)F)c(=O)[nH]c2ccc(cc12)C(F)(F)F
Show InChI InChI=1S/C18H11ClF6N2O4S/c19-10-2-4-14(28)8(5-10)6-12-11-7-9(17(20,21)22)1-3-13(11)26-16(29)15(12)27-32(30,31)18(23,24)25/h1-5,7,27-28H,6H2,(H,26,29)
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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 663n/an/an/an/a



The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Increased outward current at -40 mV mediated by mouse KCNQ2 channel expressed in Xenopus laevis oocytes


Bioorg Med Chem Lett 14: 1615-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.073
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%