Affinity Data by PubMed id=1507209

PubMed code 1507209

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM22881 (5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine \| Am...) Show SMILES Cc1nc(N)sc1CCN Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Compound is evaluated for histamine H2 receptor agonistic activity in guinea pig cerebral cortex using [3H]tiotidine as radioligand				J Med Chem 35: 3239-46 (1992) BindingDB Entry DOI: 10.7270/Q2C53N4J
Vrije Universiteit Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM7966 (2-(1H-imidazol-4-yl)ethan-1-amine \| CHEMBL544208 \|...) Show SMILES NCCc1cnc[nH]1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	6.92E+4	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Compound is evaluated for histamine H2 receptor agonistic activity in guinea pig cerebral cortex using [3H]tiotidine as radioligand				J Med Chem 35: 3239-46 (1992) BindingDB Entry DOI: 10.7270/Q2C53N4J
Vrije Universiteit Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM22883 (CHEMBL12344 \| Dimaprit \| [3-(carbamimidoylsulfanyl...) Show SMILES CN(C)CCCSC(N)=N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	2.63E+4	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Compound is evaluated for histamine H2 receptor agonistic activity in guinea pig cerebral cortex using [3H]tiotidine as radioligand				J Med Chem 35: 3239-46 (1992) BindingDB Entry DOI: 10.7270/Q2C53N4J
Vrije Universiteit Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50421967 (CHEMBL111215) Show SMILES NCCc1cnc(N)s1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	1.51E+4	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Compound is evaluated for histamine H2 receptor agonistic activity in guinea pig cerebral cortex using [3H]tiotidine as radioligand				J Med Chem 35: 3239-46 (1992) BindingDB Entry DOI: 10.7270/Q2C53N4J
Vrije Universiteit Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50421968 (CHEMBL540311) Show SMILES Cc1ncsc1CCN Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	3.55E+5	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Compound is evaluated for histamine H2 receptor agonistic activity in guinea pig cerebral cortex using [3H]tiotidine as radioligand				J Med Chem 35: 3239-46 (1992) BindingDB Entry DOI: 10.7270/Q2C53N4J
Vrije Universiteit Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50421966 (CHEMBL553981) Show SMILES Cc1nc(C)c(CCN)s1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	1.74E+5	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Compound is evaluated for histamine H2 receptor agonistic activity in guinea pig cerebral cortex using [3H]tiotidine as radioligand				J Med Chem 35: 3239-46 (1992) BindingDB Entry DOI: 10.7270/Q2C53N4J
Vrije Universiteit Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H2 receptor (Cavia porcellus (domestic guinea pig))	BDBM50421965 (CHEMBL324864) Show SMILES NCCc1csc(N)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Compound is evaluated for histamine H2 receptor agonistic activity in guinea pig cerebral cortex using [3H]tiotidine as radioligand				J Med Chem 35: 3239-46 (1992) BindingDB Entry DOI: 10.7270/Q2C53N4J
Vrije Universiteit Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%