Affinity Data by PubMed id=15084121

PubMed code 15084121

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Translocator protein (Rattus norvegicus (rat))	BDBM50122294 (CHEMBL292092 \| N-(5-fluoro-2-phenoxyphenyl)-N-(2-(...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0780	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Radiological Sciences Curated by ChEMBL					Assay Description In vitro inhibition of [11C]2 binding to Peripheral benzodiazepine receptor (PBR) in rat brain				J Med Chem 47: 2228-35 (2004) Article DOI: 10.1021/jm0304919 BindingDB Entry DOI: 10.7270/Q20G3KXQ
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50122293 (CHEMBL401000 \| CHEMBL63064 \| N-(2,5-Dimethoxy-benz...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Radiological Sciences Curated by ChEMBL					Assay Description In vitro inhibition of [11C]2 binding to Peripheral benzodiazepine receptor (PBR) in rat brain				J Med Chem 47: 2228-35 (2004) Article DOI: 10.1021/jm0304919 BindingDB Entry DOI: 10.7270/Q20G3KXQ
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50122295 (CHEMBL63065 \| N-(2-Fluoromethoxy-5-methoxy-benzyl)...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Radiological Sciences Curated by ChEMBL					Assay Description In vitro inhibition of [11C]2 binding to Peripheral benzodiazepine receptor (PBR) in rat brain				J Med Chem 47: 2228-35 (2004) Article DOI: 10.1021/jm0304919 BindingDB Entry DOI: 10.7270/Q20G3KXQ
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM22032 (1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)isoq...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	0.830	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Radiological Sciences Curated by ChEMBL					Assay Description In vitro inhibition of [11C]2 binding to Peripheral benzodiazepine receptor (PBR) in rat brain				J Med Chem 47: 2228-35 (2004) Article DOI: 10.1021/jm0304919 BindingDB Entry DOI: 10.7270/Q20G3KXQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Translocator protein (Rattus norvegicus (rat))	BDBM50144889 (CHEMBL72521 \| N-(5-Fluoro-2-phenoxy-phenyl)-N-(2-i...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Radiological Sciences Curated by ChEMBL					Assay Description In vitro inhibition of [11C]2 binding to Peripheral benzodiazepine receptor (PBR) in rat brain				J Med Chem 47: 2228-35 (2004) Article DOI: 10.1021/jm0304919 BindingDB Entry DOI: 10.7270/Q20G3KXQ
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50144887 (CHEMBL443526 \| Toluene-4-sulfonic acid 2-(2-{[acet...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	18.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Radiological Sciences Curated by ChEMBL					Assay Description In vitro inhibition of [11C]2 binding to Peripheral benzodiazepine receptor (PBR) in rat brain				J Med Chem 47: 2228-35 (2004) Article DOI: 10.1021/jm0304919 BindingDB Entry DOI: 10.7270/Q20G3KXQ
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%