Found 30 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145391
((1S,3R,8AS)-8-(2-{(4S,6S)-3-(4-HYDROXY-3-METHOXYBE...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)NC)N(Cc4ccc(O)c(OC)c4)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C34H48N2O7/c1-7-21(3)33(39)43-30-15-20(2)14-24-10-8-22(4)27(32(24)30)12-11-26-17-25(18-31(38)35-5)36(34(40)42-26)19-23-9-13-28(37)29(16-23)41-6/h8-10,13-14,16,20-22,25-27,30,32,37H,7,11-12,15,17-19H2,1-6H3,(H,35,38)/t20-,21-,22-,25+,26+,27-,30-,32-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
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| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assay |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145392
((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)OC)N(Cc4ccc(O)c(OC)c4)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C34H47NO8/c1-7-21(3)33(38)43-30-15-20(2)14-24-10-8-22(4)27(32(24)30)12-11-26-17-25(18-31(37)41-6)35(34(39)42-26)19-23-9-13-28(36)29(16-23)40-5/h8-10,13-14,16,20-22,25-27,30,32,36H,7,11-12,15,17-19H2,1-6H3/t20-,21-,22-,25+,26+,27-,30-,32-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
Inhibition of HUT78 cell adhesion to immobilized ICAM-1 protein |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145392
((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)OC)N(Cc4ccc(O)c(OC)c4)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C34H47NO8/c1-7-21(3)33(38)43-30-15-20(2)14-24-10-8-22(4)27(32(24)30)12-11-26-17-25(18-31(37)41-6)35(34(39)42-26)19-23-9-13-28(36)29(16-23)40-5/h8-10,13-14,16,20-22,25-27,30,32,36H,7,11-12,15,17-19H2,1-6H3/t20-,21-,22-,25+,26+,27-,30-,32-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assay |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145394
((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)NC)N(Cc4ccc5OCOc5c4)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C34H46N2O7/c1-6-21(3)33(38)43-30-14-20(2)13-24-9-7-22(4)27(32(24)30)11-10-26-16-25(17-31(37)35-5)36(34(39)42-26)18-23-8-12-28-29(15-23)41-19-40-28/h7-9,12-13,15,20-22,25-27,30,32H,6,10-11,14,16-19H2,1-5H3,(H,35,37)/t20-,21-,22-,25+,26+,27-,30-,32-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
Inhibition of HUT78 cell adhesion to immobilized ICAM-1 protein |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145391
((1S,3R,8AS)-8-(2-{(4S,6S)-3-(4-HYDROXY-3-METHOXYBE...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)NC)N(Cc4ccc(O)c(OC)c4)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C34H48N2O7/c1-7-21(3)33(39)43-30-15-20(2)14-24-10-8-22(4)27(32(24)30)12-11-26-17-25(18-31(38)35-5)36(34(40)42-26)19-23-9-13-28(37)29(16-23)41-6/h8-10,13-14,16,20-22,25-27,30,32,37H,7,11-12,15,17-19H2,1-6H3,(H,35,38)/t20-,21-,22-,25+,26+,27-,30-,32-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assay |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145395
((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)NC)N(Cc4cccc(OC)c4)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C34H48N2O6/c1-7-22(3)33(38)42-30-16-21(2)15-25-12-11-23(4)29(32(25)30)14-13-28-18-26(19-31(37)35-5)36(34(39)41-28)20-24-9-8-10-27(17-24)40-6/h8-12,15,17,21-23,26,28-30,32H,7,13-14,16,18-20H2,1-6H3,(H,35,37)/t21-,22-,23-,26+,28+,29-,30-,32-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
Inhibition of HUT78 cell adhesion to immobilized ICAM-1 protein |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145396
((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-3,7-di...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)NC)N(Cc4ccc(cc4)C(=O)NC)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C35H49N3O6/c1-7-22(3)34(41)44-30-17-21(2)16-26-11-8-23(4)29(32(26)30)15-14-28-18-27(19-31(39)36-5)38(35(42)43-28)20-24-9-12-25(13-10-24)33(40)37-6/h8-13,16,21-23,27-30,32H,7,14-15,17-20H2,1-6H3,(H,36,39)(H,37,40)/t21-,22-,23-,27+,28+,29-,30-,32-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 620 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assay |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145390
((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)OC)N(CCc4ccc(O)c(OC)c4)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C35H49NO8/c1-7-22(3)34(39)44-31-17-21(2)16-25-10-8-23(4)28(33(25)31)12-11-27-19-26(20-32(38)42-6)36(35(40)43-27)15-14-24-9-13-29(37)30(18-24)41-5/h8-10,13,16,18,21-23,26-28,31,33,37H,7,11-12,14-15,17,19-20H2,1-6H3/t21-,22-,23-,26+,27+,28-,31-,33-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 640 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
Inhibition of HUT78 cell adhesion to immobilized ICAM-1 protein |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145388
((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)OC)N(Cc4cccc(OC)c4)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C34H47NO7/c1-7-22(3)33(37)42-30-16-21(2)15-25-12-11-23(4)29(32(25)30)14-13-28-18-26(19-31(36)40-6)35(34(38)41-28)20-24-9-8-10-27(17-24)39-5/h8-12,15,17,21-23,26,28-30,32H,7,13-14,16,18-20H2,1-6H3/t21-,22-,23-,26+,28+,29-,30-,32-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
Inhibition of HUT78 cell adhesion to immobilized ICAM-1 protein |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145398
((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)NC)N(CCc4ccc(O)c(OC)c4)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C35H50N2O7/c1-7-22(3)34(40)44-31-17-21(2)16-25-10-8-23(4)28(33(25)31)12-11-27-19-26(20-32(39)36-5)37(35(41)43-27)15-14-24-9-13-29(38)30(18-24)42-6/h8-10,13,16,18,21-23,26-28,31,33,38H,7,11-12,14-15,17,19-20H2,1-6H3,(H,36,39)/t21-,22-,23-,26+,27+,28-,31-,33-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assay |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145385
(4-((1R,5R)-6-{2-[(1S,2S,6R,8S,8aR)-2,6-Dimethyl-8-...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)NC)N(Cc4ccc(cc4)C(O)=O)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C34H46N2O7/c1-6-21(3)33(40)43-29-16-20(2)15-25-10-7-22(4)28(31(25)29)14-13-27-17-26(18-30(37)35-5)36(34(41)42-27)19-23-8-11-24(12-9-23)32(38)39/h7-12,15,20-22,26-29,31H,6,13-14,16-19H2,1-5H3,(H,35,37)(H,38,39)/t20-,21-,22-,26+,27+,28-,29-,31-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 870 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
Inhibition of HUT78 cell adhesion to immobilized ICAM-1 protein |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145397
((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)OC)N(Cc4ccc5OCOc5c4)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C34H45NO8/c1-6-21(3)33(37)43-30-14-20(2)13-24-9-7-22(4)27(32(24)30)11-10-26-16-25(17-31(36)39-5)35(34(38)42-26)18-23-8-12-28-29(15-23)41-19-40-28/h7-9,12-13,15,20-22,25-27,30,32H,6,10-11,14,16-19H2,1-5H3/t20-,21-,22-,25+,26+,27-,30-,32-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assay |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145386
((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)NC)N(Cc4ccc5OC(F)(F)Oc5c4)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C34H44F2N2O7/c1-6-20(3)32(40)43-29-14-19(2)13-23-9-7-21(4)26(31(23)29)11-10-25-16-24(17-30(39)37-5)38(33(41)42-25)18-22-8-12-27-28(15-22)45-34(35,36)44-27/h7-9,12-13,15,19-21,24-26,29,31H,6,10-11,14,16-18H2,1-5H3,(H,37,39)/t19-,20-,21-,24+,25+,26-,29-,31-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
Inhibition of HUT78 cell adhesion to immobilized ICAM-1 protein |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145393
((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)OC)N(Cc4ccc(cc4)C(=O)NC)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C35H48N2O7/c1-7-22(3)34(40)44-30-17-21(2)16-26-11-8-23(4)29(32(26)30)15-14-28-18-27(19-31(38)42-6)37(35(41)43-28)20-24-9-12-25(13-10-24)33(39)36-5/h8-13,16,21-23,27-30,32H,7,14-15,17-20H2,1-6H3,(H,36,39)/t21-,22-,23-,27+,28+,29-,30-,32-/m0/s1 | PDB
UniProtKB/SwissProt
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| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assay |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145399
((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)NC)N(Cc4ccc(cc4)C(C)(C)O)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C36H52N2O6/c1-8-23(3)34(40)44-31-18-22(2)17-26-12-9-24(4)30(33(26)31)16-15-29-19-28(20-32(39)37-7)38(35(41)43-29)21-25-10-13-27(14-11-25)36(5,6)42/h9-14,17,22-24,28-31,33,42H,8,15-16,18-21H2,1-7H3,(H,37,39)/t22-,23-,24-,28+,29+,30-,31-,33-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
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PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assay |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145397
((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)OC)N(Cc4ccc5OCOc5c4)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C34H45NO8/c1-6-21(3)33(37)43-30-14-20(2)13-24-9-7-22(4)27(32(24)30)11-10-26-16-25(17-31(36)39-5)35(34(38)42-26)18-23-8-12-28-29(15-23)41-19-40-28/h7-9,12-13,15,20-22,25-27,30,32H,6,10-11,14,16-19H2,1-5H3/t20-,21-,22-,25+,26+,27-,30-,32-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
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Similars
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PubMed
| n/a | n/a | 2.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assay |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145387
((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)OC)N(Cc4ccc(cc4)C(C)(C)O)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C36H51NO7/c1-8-23(3)34(39)44-31-18-22(2)17-26-12-9-24(4)30(33(26)31)16-15-29-19-28(20-32(38)42-7)37(35(40)43-29)21-25-10-13-27(14-11-25)36(5,6)41/h9-14,17,22-24,28-31,33,41H,8,15-16,18-21H2,1-7H3/t22-,23-,24-,28+,29+,30-,31-,33-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
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PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assay |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50004774
((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19?,20-,21-,23-/m0/s1 | PDB
UniProtKB/SwissProt
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MCE
MMDB
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Patents
Similars
| Article
PubMed
| n/a | n/a | 3.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
Inhibition of HUT78 cell adhesion to immobilized ICAM-1 protein |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145388
((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)OC)N(Cc4cccc(OC)c4)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C34H47NO7/c1-7-22(3)33(37)42-30-16-21(2)15-25-12-11-23(4)29(32(25)30)14-13-28-18-26(19-31(36)40-6)35(34(38)41-28)20-24-9-8-10-27(17-24)39-5/h8-12,15,17,21-23,26,28-30,32H,7,13-14,16,18-20H2,1-6H3/t21-,22-,23-,26+,28+,29-,30-,32-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
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antibodypedia
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| Article
PubMed
| n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
Inhibition of HUT78 cell adhesion to immobilized ICAM-1 protein |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145386
((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)NC)N(Cc4ccc5OC(F)(F)Oc5c4)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C34H44F2N2O7/c1-6-20(3)32(40)43-29-14-19(2)13-23-9-7-21(4)26(31(23)29)11-10-25-16-24(17-30(39)37-5)38(33(41)42-25)18-22-8-12-27-28(15-22)45-34(35,36)44-27/h7-9,12-13,15,19-21,24-26,29,31H,6,10-11,14,16-18H2,1-5H3,(H,37,39)/t19-,20-,21-,24+,25+,26-,29-,31-/m0/s1 | PDB
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| n/a | n/a | 5.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
Inhibition of HUT78 cell adhesion to immobilized ICAM-1 protein |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145394
((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)NC)N(Cc4ccc5OCOc5c4)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C34H46N2O7/c1-6-21(3)33(38)43-30-14-20(2)13-24-9-7-22(4)27(32(24)30)11-10-26-16-25(17-31(37)35-5)36(34(39)42-26)18-23-8-12-28-29(15-23)41-19-40-28/h7-9,12-13,15,20-22,25-27,30,32H,6,10-11,14,16-19H2,1-5H3,(H,35,37)/t20-,21-,22-,25+,26+,27-,30-,32-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
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Similars
| Article
PubMed
| n/a | n/a | 6.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assay |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145395
((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)NC)N(Cc4cccc(OC)c4)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C34H48N2O6/c1-7-22(3)33(38)42-30-16-21(2)15-25-12-11-23(4)29(32(25)30)14-13-28-18-26(19-31(37)35-5)36(34(39)41-28)20-24-9-8-10-27(17-24)40-6/h8-12,15,17,21-23,26,28-30,32H,7,13-14,16,18-20H2,1-6H3,(H,35,37)/t21-,22-,23-,26+,28+,29-,30-,32-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
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antibodypedia
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PubMed
| n/a | n/a | 6.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
Inhibition of HUT78 cell adhesion to immobilized ICAM-1 protein |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145387
((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)OC)N(Cc4ccc(cc4)C(C)(C)O)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C36H51NO7/c1-8-23(3)34(39)44-31-18-22(2)17-26-12-9-24(4)30(33(26)31)16-15-29-19-28(20-32(38)42-7)37(35(40)43-29)21-25-10-13-27(14-11-25)36(5,6)41/h9-14,17,22-24,28-31,33,41H,8,15-16,18-21H2,1-7H3/t22-,23-,24-,28+,29+,30-,31-,33-/m0/s1 | PDB
UniProtKB/SwissProt
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Similars
| Article
PubMed
| n/a | n/a | 7.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assay |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145398
((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)NC)N(CCc4ccc(O)c(OC)c4)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C35H50N2O7/c1-7-22(3)34(40)44-31-17-21(2)16-25-10-8-23(4)28(33(25)31)12-11-27-19-26(20-32(39)36-5)37(35(41)43-27)15-14-24-9-13-29(38)30(18-24)42-6/h8-10,13,16,18,21-23,26-28,31,33,38H,7,11-12,14-15,17,19-20H2,1-6H3,(H,36,39)/t21-,22-,23-,26+,27+,28-,31-,33-/m0/s1 | PDB
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Similars
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PubMed
| n/a | n/a | 9.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assay |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145390
((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-(2-{...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)OC)N(CCc4ccc(O)c(OC)c4)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C35H49NO8/c1-7-22(3)34(39)44-31-17-21(2)16-25-10-8-23(4)28(33(25)31)12-11-27-19-26(20-32(38)42-6)36(35(40)43-27)15-14-24-9-13-29(37)30(18-24)41-5/h8-10,13,16,18,21-23,26-28,31,33,37H,7,11-12,14-15,17,19-20H2,1-6H3/t21-,22-,23-,26+,27+,28-,31-,33-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
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antibodypedia
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Similars
| Article
PubMed
| n/a | n/a | 2.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assay |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145396
((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-3,7-di...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)NC)N(Cc4ccc(cc4)C(=O)NC)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C35H49N3O6/c1-7-22(3)34(41)44-30-17-21(2)16-26-11-8-23(4)29(32(26)30)15-14-28-18-27(19-31(39)36-5)38(35(42)43-28)20-24-9-12-25(13-10-24)33(40)37-6/h8-13,16,21-23,27-30,32H,7,14-15,17-20H2,1-6H3,(H,36,39)(H,37,40)/t21-,22-,23-,27+,28+,29-,30-,32-/m0/s1 | PDB
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PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assay |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145385
(4-((1R,5R)-6-{2-[(1S,2S,6R,8S,8aR)-2,6-Dimethyl-8-...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)NC)N(Cc4ccc(cc4)C(O)=O)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C34H46N2O7/c1-6-21(3)33(40)43-29-16-20(2)15-25-10-7-22(4)28(31(25)29)14-13-27-17-26(18-30(37)35-5)36(34(41)42-27)19-23-8-11-24(12-9-23)32(38)39/h7-12,15,20-22,26-29,31H,6,13-14,16-19H2,1-5H3,(H,35,37)(H,38,39)/t20-,21-,22-,26+,27+,28-,29-,31-/m0/s1 | PDB
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| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
Inhibition of HUT78 cell adhesion to immobilized ICAM-1 protein |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145389
((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)OC)N(Cc4ccc5OC(F)(F)Oc5c4)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C34H43F2NO8/c1-6-20(3)32(39)43-29-14-19(2)13-23-9-7-21(4)26(31(23)29)11-10-25-16-24(17-30(38)41-5)37(33(40)42-25)18-22-8-12-27-28(15-22)45-34(35,36)44-27/h7-9,12-13,15,19-21,24-26,29,31H,6,10-11,14,16-18H2,1-5H3/t19-,20-,21-,24+,25+,26-,29-,31-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
Inhibition of HUT78 cell adhesion to immobilized ICAM-1 protein |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145393
((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)OC)N(Cc4ccc(cc4)C(=O)NC)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C35H48N2O7/c1-7-22(3)34(40)44-30-17-21(2)16-26-11-8-23(4)29(32(26)30)15-14-28-18-27(19-31(38)42-6)37(35(41)43-28)20-24-9-12-25(13-10-24)33(39)36-5/h8-13,16,21-23,27-30,32H,7,14-15,17-20H2,1-6H3,(H,36,39)/t21-,22-,23-,27+,28+,29-,30-,32-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
Inhibition of HUT78 cell adhesion to immobilized ICAM-1 protein |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human)) | BDBM50145389
((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-{2-[...)Show SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)OC)N(Cc4ccc5OC(F)(F)Oc5c4)C(=O)O3)[C@@H]12 |c:13,t:11| Show InChI InChI=1S/C34H43F2NO8/c1-6-20(3)32(39)43-29-14-19(2)13-23-9-7-21(4)26(31(23)29)11-10-25-16-24(17-30(38)41-5)37(33(40)42-25)18-22-8-12-27-28(15-22)45-34(35,36)44-27/h7-9,12-13,15,19-21,24-26,29,31H,6,10-11,14,16-18H2,1-5H3/t19-,20-,21-,24+,25+,26-,29-,31-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
In vitro inhibition of recombinant ICAM-1 binding to purified immobilized LFA-1 using cell-free assay |
Bioorg Med Chem Lett 14: 2483-7 (2004)
Article DOI: 10.1016/j.bmcl.2004.03.006
BindingDB Entry DOI: 10.7270/Q2N58KT2 |
More data for this
Ligand-Target Pair | |
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