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PubMed code 15163193

Compile data set for download or QSAR
Found 19 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50370343
PNG
(CHEMBL1790802)
Show SMILES CC[C@@H](C)[C@H](NC(=O)CC[C@@H]1NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC1=O)C(O)=O
Show InChI InChI=1S/C25H35N4O12P/c1-3-13(2)21(25(36)37)29-19(30)10-8-16-23(34)28-18(12-14-4-6-15(7-5-14)41-42(38,39)40)24(35)27-17(22(33)26-16)9-11-20(31)32/h4-7,13,16-18,21H,3,8-12H2,1-2H3,(H,26,33)(H,27,35)(H,28,34)(H,29,30)(H,31,32)(H,36,37)(H2,38,39,40)/t13-,16+,17+,18+,21+/m1/s1
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n/an/a 1.10E+3n/an/an/an/an/an/a



University of Rhode Island

Curated by ChEMBL


Assay Description
Concentration of compoound required for inhibiting the binding of the fluorescent probe to the c-Src tyrosine kinase SH2 domain by 50%

J Med Chem 47: 3131-41 (2004)


Article DOI: 10.1021/jm040008+
BindingDB Entry DOI: 10.7270/Q25B0370
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50370348
PNG
(CHEMBL1790811)
Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)CC[C@@H]1NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC1=O)C(O)=O
Show InChI InChI=1S/C25H35N4O12P/c1-3-13(2)21(25(36)37)29-23(34)16(9-11-20(31)32)26-19(30)10-8-17-22(33)28-18(24(35)27-17)12-14-4-6-15(7-5-14)41-42(38,39)40/h4-7,13,16-18,21H,3,8-12H2,1-2H3,(H,26,30)(H,27,35)(H,28,33)(H,29,34)(H,31,32)(H,36,37)(H2,38,39,40)/t13-,16+,17+,18+,21+/m1/s1
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n/an/a 1.20E+3n/an/an/an/an/an/a



University of Rhode Island

Curated by ChEMBL


Assay Description
Concentration of compoound required for inhibiting the binding of the fluorescent probe to the c-Src tyrosine kinase SH2 domain by 50%

J Med Chem 47: 3131-41 (2004)


Article DOI: 10.1021/jm040008+
BindingDB Entry DOI: 10.7270/Q25B0370
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50370341
PNG
(CHEMBL1790810)
Show SMILES CC[C@@H](C)[C@H](NC(=O)C[C@@H]1NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC1=O)C(O)=O
Show InChI InChI=1S/C24H33N4O12P/c1-3-12(2)20(24(35)36)28-18(29)11-17-23(34)26-16(10-13-4-6-14(7-5-13)40-41(37,38)39)22(33)25-15(21(32)27-17)8-9-19(30)31/h4-7,12,15-17,20H,3,8-11H2,1-2H3,(H,25,33)(H,26,34)(H,27,32)(H,28,29)(H,30,31)(H,35,36)(H2,37,38,39)/t12-,15+,16+,17+,20+/m1/s1
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n/an/a 1.50E+3n/an/an/an/an/an/a



University of Rhode Island

Curated by ChEMBL


Assay Description
Concentration of compoound required for inhibiting the binding of the fluorescent probe to the c-Src tyrosine kinase SH2 domain by 50%

J Med Chem 47: 3131-41 (2004)


Article DOI: 10.1021/jm040008+
BindingDB Entry DOI: 10.7270/Q25B0370
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50370351
PNG
(CHEMBL1790806)
Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H]1CCC(=O)N[C@@H](Cc2ccc(OP(O)(O)=O)cc2)C(=O)N1)C(O)=O
Show InChI InChI=1S/C25H35N4O12P/c1-3-13(2)21(25(36)37)29-23(34)17(9-11-20(31)32)27-22(33)16-8-10-19(30)26-18(24(35)28-16)12-14-4-6-15(7-5-14)41-42(38,39)40/h4-7,13,16-18,21H,3,8-12H2,1-2H3,(H,26,30)(H,27,33)(H,28,35)(H,29,34)(H,31,32)(H,36,37)(H2,38,39,40)/t13-,16+,17+,18+,21+/m1/s1
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n/an/a 3.30E+3n/an/an/an/an/an/a



University of Rhode Island

Curated by ChEMBL


Assay Description
Concentration of compoound required for inhibiting the binding of the fluorescent probe to the c-Src tyrosine kinase SH2 domain by 50%

J Med Chem 47: 3131-41 (2004)


Article DOI: 10.1021/jm040008+
BindingDB Entry DOI: 10.7270/Q25B0370
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50370352
PNG
(CHEMBL1790807)
Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@@H]1CCC(=O)N[C@@H](Cc2ccc(OP(O)(O)=O)cc2)C(=O)N[C@@H](CCC(O)=O)C(=O)N1)C(O)=O
Show InChI InChI=1S/C25H35N4O12P/c1-3-13(2)21(25(36)37)29-23(34)16-8-10-19(30)26-18(12-14-4-6-15(7-5-14)41-42(38,39)40)24(35)28-17(22(33)27-16)9-11-20(31)32/h4-7,13,16-18,21H,3,8-12H2,1-2H3,(H,26,30)(H,27,33)(H,28,35)(H,29,34)(H,31,32)(H,36,37)(H2,38,39,40)/t13-,16+,17+,18+,21+/m1/s1
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n/an/a 5.90E+3n/an/an/an/an/an/a



University of Rhode Island

Curated by ChEMBL


Assay Description
Concentration of compoound required for inhibiting the binding of the fluorescent probe to the c-Src tyrosine kinase SH2 domain by 50%

J Med Chem 47: 3131-41 (2004)


Article DOI: 10.1021/jm040008+
BindingDB Entry DOI: 10.7270/Q25B0370
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50074242
PNG
((2S,3S)-2-((S)-2-{(S)-2-[(S)-2-Acetylamino-3-(4-ph...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(O)=O
Show InChI InChI=1S/C27H39N4O14P/c1-4-14(2)23(27(40)41)31-25(38)19(10-12-22(35)36)29-24(37)18(9-11-21(33)34)30-26(39)20(28-15(3)32)13-16-5-7-17(8-6-16)45-46(42,43)44/h5-8,14,18-20,23H,4,9-13H2,1-3H3,(H,28,32)(H,29,37)(H,30,39)(H,31,38)(H,33,34)(H,35,36)(H,40,41)(H2,42,43,44)/t14-,18-,19-,20-,23-/m0/s1
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n/an/a 6.50E+3n/an/an/an/an/an/a



University of Rhode Island

Curated by ChEMBL


Assay Description
Concentration of compoound required for inhibiting the binding of the fluorescent probe to the c-Src tyrosine kinase SH2 domain by 50%

J Med Chem 47: 3131-41 (2004)


Article DOI: 10.1021/jm040008+
BindingDB Entry DOI: 10.7270/Q25B0370
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50370347
PNG
(CHEMBL1790814)
Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)C[C@@H]1NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC1=O)C(O)=O
Show InChI InChI=1S/C24H33N4O12P/c1-3-12(2)20(24(35)36)28-21(32)15(8-9-19(30)31)25-18(29)11-17-23(34)26-16(22(33)27-17)10-13-4-6-14(7-5-13)40-41(37,38)39/h4-7,12,15-17,20H,3,8-11H2,1-2H3,(H,25,29)(H,26,34)(H,27,33)(H,28,32)(H,30,31)(H,35,36)(H2,37,38,39)/t12-,15+,16+,17+,20+/m1/s1
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n/an/a 1.21E+4n/an/an/an/an/an/a



University of Rhode Island

Curated by ChEMBL


Assay Description
Concentration of compoound required for inhibiting the binding of the fluorescent probe to the c-Src tyrosine kinase SH2 domain by 50%

J Med Chem 47: 3131-41 (2004)


Article DOI: 10.1021/jm040008+
BindingDB Entry DOI: 10.7270/Q25B0370
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50148012
PNG
((S)-2-(3-{(S)-2-[2-((S)-Acetylamino)-3-(4-phosphon...)
Show SMILES CC(C)[C@H](NC(=O)C[C@@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(O)=O
Show InChI InChI=1S/C26H37N4O14P/c1-13(2)23(26(39)40)30-20(32)11-16(12-22(35)36)28-24(37)18(8-9-21(33)34)29-25(38)19(27-14(3)31)10-15-4-6-17(7-5-15)44-45(41,42)43/h4-7,13,16,18-19,23H,8-12H2,1-3H3,(H,27,31)(H,28,37)(H,29,38)(H,30,32)(H,33,34)(H,35,36)(H,39,40)(H2,41,42,43)/t16-,18-,19-,23-/m0/s1
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n/an/a 2.57E+4n/an/an/an/an/an/a



University of Rhode Island

Curated by ChEMBL


Assay Description
Concentration of compoound required for inhibiting the binding of the fluorescent probe to the c-Src tyrosine kinase SH2 domain by 50%

J Med Chem 47: 3131-41 (2004)


Article DOI: 10.1021/jm040008+
BindingDB Entry DOI: 10.7270/Q25B0370
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50148022
PNG
(4-{(S)-2-[2-((R)-Acetylamino)-3-(4-phosphonooxy-ph...)
Show SMILES CC(C)[C@H](NC(=O)C[C@@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(O)=O)C(O)=O
Show InChI InChI=1S/C25H35N4O14P/c1-12(2)20(24(36)37)28-18(31)11-15(6-9-19(32)33)27-23(35)21(25(38)39)29-22(34)17(26-13(3)30)10-14-4-7-16(8-5-14)43-44(40,41)42/h4-5,7-8,12,15,17,20-21H,6,9-11H2,1-3H3,(H,26,30)(H,27,35)(H,28,31)(H,29,34)(H,32,33)(H,36,37)(H,38,39)(H2,40,41,42)/t15-,17+,20+,21-/m1/s1
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n/an/a 3.46E+4n/an/an/an/an/an/a



University of Rhode Island

Curated by ChEMBL


Assay Description
Concentration of compoound required for inhibiting the binding of the fluorescent probe to the c-Src tyrosine kinase SH2 domain by 50%

J Med Chem 47: 3131-41 (2004)


Article DOI: 10.1021/jm040008+
BindingDB Entry DOI: 10.7270/Q25B0370
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50370354
PNG
(CHEMBL1790805)
Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)CC[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(O)=O)C(O)=O
Show InChI InChI=1S/C27H39N4O14P/c1-4-14(2)23(27(40)41)31-24(36)18(10-12-22(34)35)29-21(33)11-9-19(26(38)39)30-25(37)20(28-15(3)32)13-16-5-7-17(8-6-16)45-46(42,43)44/h5-8,14,18-20,23H,4,9-13H2,1-3H3,(H,28,32)(H,29,33)(H,30,37)(H,31,36)(H,34,35)(H,38,39)(H,40,41)(H2,42,43,44)/t14-,18+,19+,20+,23+/m1/s1
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n/an/a 6.95E+4n/an/an/an/an/an/a



University of Rhode Island

Curated by ChEMBL


Assay Description
Concentration of compoound required for inhibiting the binding of the fluorescent probe to the c-Src tyrosine kinase SH2 domain by 50%

J Med Chem 47: 3131-41 (2004)


Article DOI: 10.1021/jm040008+
BindingDB Entry DOI: 10.7270/Q25B0370
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50370353
PNG
(CHEMBL1790809)
Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)C[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(O)=O)C(O)=O
Show InChI InChI=1S/C26H37N4O14P/c1-4-13(2)22(26(39)40)30-23(35)17(9-10-21(33)34)28-20(32)12-19(25(37)38)29-24(36)18(27-14(3)31)11-15-5-7-16(8-6-15)44-45(41,42)43/h5-8,13,17-19,22H,4,9-12H2,1-3H3,(H,27,31)(H,28,32)(H,29,36)(H,30,35)(H,33,34)(H,37,38)(H,39,40)(H2,41,42,43)/t13-,17+,18+,19+,22+/m1/s1
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n/an/a 7.54E+4n/an/an/an/an/an/a



University of Rhode Island

Curated by ChEMBL


Assay Description
Concentration of compoound required for inhibiting the binding of the fluorescent probe to the c-Src tyrosine kinase SH2 domain by 50%

J Med Chem 47: 3131-41 (2004)


Article DOI: 10.1021/jm040008+
BindingDB Entry DOI: 10.7270/Q25B0370
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50148024
PNG
((S)-2-((S)-3-{(S)-2-[2-Amino-3-(4-phosphonooxy-phe...)
Show SMILES CC(C)[C@H](NC(=O)C[C@@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)Cc1ccc(OP(O)(O)=O)cc1)C(O)=O
Show InChI InChI=1S/C24H35N4O13P/c1-12(2)21(24(36)37)28-18(29)10-14(11-20(32)33)26-23(35)17(7-8-19(30)31)27-22(34)16(25)9-13-3-5-15(6-4-13)41-42(38,39)40/h3-6,12,14,16-17,21H,7-11,25H2,1-2H3,(H,26,35)(H,27,34)(H,28,29)(H,30,31)(H,32,33)(H,36,37)(H2,38,39,40)/t14-,16-,17-,21-/m0/s1
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n/an/a 7.63E+4n/an/an/an/an/an/a



University of Rhode Island

Curated by ChEMBL


Assay Description
Concentration of compoound required for inhibiting the binding of the fluorescent probe to the c-Src tyrosine kinase SH2 domain by 50%

J Med Chem 47: 3131-41 (2004)


Article DOI: 10.1021/jm040008+
BindingDB Entry DOI: 10.7270/Q25B0370
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50370349
PNG
(CHEMBL1790804)
Show SMILES CC[C@@H](C)[C@H](NC(=O)CC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(O)=O)C(O)=O
Show InChI InChI=1S/C27H39N4O14P/c1-4-14(2)23(27(40)41)31-21(33)11-9-19(26(38)39)30-24(36)18(10-12-22(34)35)29-25(37)20(28-15(3)32)13-16-5-7-17(8-6-16)45-46(42,43)44/h5-8,14,18-20,23H,4,9-13H2,1-3H3,(H,28,32)(H,29,37)(H,30,36)(H,31,33)(H,34,35)(H,38,39)(H,40,41)(H2,42,43,44)/t14-,18+,19+,20+,23+/m1/s1
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n/an/a 8.07E+4n/an/an/an/an/an/a



University of Rhode Island

Curated by ChEMBL


Assay Description
Concentration of compoound required for inhibiting the binding of the fluorescent probe to the c-Src tyrosine kinase SH2 domain by 50%

J Med Chem 47: 3131-41 (2004)


Article DOI: 10.1021/jm040008+
BindingDB Entry DOI: 10.7270/Q25B0370
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50148020
PNG
((R)-4-{(S)-2-[2-Amino-3-(4-phosphonooxy-phenyl)-pr...)
Show SMILES CC(C)[C@H](NC(=O)C[C@@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccc(OP(O)(O)=O)cc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C23H33N4O13P/c1-11(2)18(22(33)34)26-16(28)10-13(5-8-17(29)30)25-21(32)19(23(35)36)27-20(31)15(24)9-12-3-6-14(7-4-12)40-41(37,38)39/h3-4,6-7,11,13,15,18-19H,5,8-10,24H2,1-2H3,(H,25,32)(H,26,28)(H,27,31)(H,29,30)(H,33,34)(H,35,36)(H2,37,38,39)/t13-,15+,18+,19-/m1/s1
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n/an/a 8.32E+4n/an/an/an/an/an/a



University of Rhode Island

Curated by ChEMBL


Assay Description
Concentration of compoound required for inhibiting the binding of the fluorescent probe to the c-Src tyrosine kinase SH2 domain by 50%

J Med Chem 47: 3131-41 (2004)


Article DOI: 10.1021/jm040008+
BindingDB Entry DOI: 10.7270/Q25B0370
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50370344
PNG
(CHEMBL1790815)
Show SMILES CC[C@@H](C)[C@H](NC(=O)C[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(O)=O)C(O)=O
Show InChI InChI=1S/C26H37N4O14P/c1-4-13(2)22(26(39)40)30-20(32)12-19(25(37)38)29-23(35)17(9-10-21(33)34)28-24(36)18(27-14(3)31)11-15-5-7-16(8-6-15)44-45(41,42)43/h5-8,13,17-19,22H,4,9-12H2,1-3H3,(H,27,31)(H,28,36)(H,29,35)(H,30,32)(H,33,34)(H,37,38)(H,39,40)(H2,41,42,43)/t13-,17+,18+,19+,22+/m1/s1
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n/an/a 9.07E+4n/an/an/an/an/an/a



University of Rhode Island

Curated by ChEMBL


Assay Description
Concentration of compoound required for inhibiting the binding of the fluorescent probe to the c-Src tyrosine kinase SH2 domain by 50%

J Med Chem 47: 3131-41 (2004)


Article DOI: 10.1021/jm040008+
BindingDB Entry DOI: 10.7270/Q25B0370
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50370342
PNG
(CHEMBL1790817)
Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)C[C@H](NC(=O)[C@@H](N)Cc1ccc(OP(O)(O)=O)cc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C24H35N4O13P/c1-3-12(2)20(24(36)37)28-22(33)16(8-9-19(30)31)26-18(29)11-17(23(34)35)27-21(32)15(25)10-13-4-6-14(7-5-13)41-42(38,39)40/h4-7,12,15-17,20H,3,8-11,25H2,1-2H3,(H,26,29)(H,27,32)(H,28,33)(H,30,31)(H,34,35)(H,36,37)(H2,38,39,40)/t12-,15+,16+,17+,20+/m1/s1
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UniProtKB/SwissProt

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n/an/a>1.00E+5n/an/an/an/an/an/a



University of Rhode Island

Curated by ChEMBL


Assay Description
Concentration of compoound required for inhibiting the binding of the fluorescent probe to the c-Src tyrosine kinase SH2 domain by 50%

J Med Chem 47: 3131-41 (2004)


Article DOI: 10.1021/jm040008+
BindingDB Entry DOI: 10.7270/Q25B0370
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50370346
PNG
(CHEMBL1790812)
Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)CC[C@H](NC(=O)[C@@H](N)Cc1ccc(OP(O)(O)=O)cc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C25H37N4O13P/c1-3-13(2)21(25(37)38)29-23(34)17(9-11-20(31)32)27-19(30)10-8-18(24(35)36)28-22(33)16(26)12-14-4-6-15(7-5-14)42-43(39,40)41/h4-7,13,16-18,21H,3,8-12,26H2,1-2H3,(H,27,30)(H,28,33)(H,29,34)(H,31,32)(H,35,36)(H,37,38)(H2,39,40,41)/t13-,16+,17+,18+,21+/m1/s1
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UniProtKB/SwissProt

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UniChem

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n/an/a>1.00E+5n/an/an/an/an/an/a



University of Rhode Island

Curated by ChEMBL


Assay Description
Concentration of compoound required for inhibiting the binding of the fluorescent probe to the c-Src tyrosine kinase SH2 domain by 50%

J Med Chem 47: 3131-41 (2004)


Article DOI: 10.1021/jm040008+
BindingDB Entry DOI: 10.7270/Q25B0370
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50370345
PNG
(CHEMBL1790813)
Show SMILES CC[C@@H](C)[C@H](NC(=O)CC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)Cc1ccc(OP(O)(O)=O)cc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C25H37N4O13P/c1-3-13(2)21(25(37)38)29-19(30)10-8-18(24(35)36)28-23(34)17(9-11-20(31)32)27-22(33)16(26)12-14-4-6-15(7-5-14)42-43(39,40)41/h4-7,13,16-18,21H,3,8-12,26H2,1-2H3,(H,27,33)(H,28,34)(H,29,30)(H,31,32)(H,35,36)(H,37,38)(H2,39,40,41)/t13-,16+,17+,18+,21+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

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DrugBank
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UniChem

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PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Rhode Island

Curated by ChEMBL


Assay Description
Concentration of compoound required for inhibiting the binding of the fluorescent probe to the c-Src tyrosine kinase SH2 domain by 50%

J Med Chem 47: 3131-41 (2004)


Article DOI: 10.1021/jm040008+
BindingDB Entry DOI: 10.7270/Q25B0370
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50370350
PNG
(CHEMBL1790816)
Show SMILES CC[C@@H](C)[C@H](NC(=O)C[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)Cc1ccc(OP(O)(O)=O)cc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C24H35N4O13P/c1-3-12(2)20(24(36)37)28-18(29)11-17(23(34)35)27-22(33)16(8-9-19(30)31)26-21(32)15(25)10-13-4-6-14(7-5-13)41-42(38,39)40/h4-7,12,15-17,20H,3,8-11,25H2,1-2H3,(H,26,32)(H,27,33)(H,28,29)(H,30,31)(H,34,35)(H,36,37)(H2,38,39,40)/t12-,15+,16+,17+,20+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Rhode Island

Curated by ChEMBL


Assay Description
Concentration of compoound required for inhibiting the binding of the fluorescent probe to the c-Src tyrosine kinase SH2 domain by 50%

J Med Chem 47: 3131-41 (2004)


Article DOI: 10.1021/jm040008+
BindingDB Entry DOI: 10.7270/Q25B0370
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%