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PubMed code 15169829

Compile data set for download or QSAR
Found 3 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))
BDBM86174
PNG
(CAS_486-12-4 | NSC_5282443 | Triprolidine)
Show SMILES Cc1ccc(cc1)C(=CCN1CCCC1)c1ccccn1 |w:8.9|
Show InChI InChI=1S/C19H22N2/c1-16-7-9-17(10-8-16)18(19-6-2-3-12-20-19)11-15-21-13-4-5-14-21/h2-3,6-12H,4-5,13-15H2,1H3
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Article
PubMed
0.930n/an/an/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by PDSP Ki Database




J Pharmacol Exp Ther 311: 274-81 (2004)


Article DOI: 10.1124/jpet.104.070086
BindingDB Entry DOI: 10.7270/Q27S7MB9
More data for this
Ligand-Target Pair
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))
BDBM86032
PNG
(trans-H2-PAT(-) | trans-PAT)
Show SMILES CN(C)[C@H]1C[C@H](c2ccccc2)c2ccccc2C1 |r|
Show InChI InChI=1S/C18H21N/c1-19(2)16-12-15-10-6-7-11-17(15)18(13-16)14-8-4-3-5-9-14/h3-11,16,18H,12-13H2,1-2H3/t16-,18-/m1/s1
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Article
PubMed
1.15n/an/an/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by PDSP Ki Database




J Pharmacol Exp Ther 311: 274-81 (2004)


Article DOI: 10.1124/jpet.104.070086
BindingDB Entry DOI: 10.7270/Q27S7MB9
More data for this
Ligand-Target Pair
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))
BDBM7966
PNG
(2-(1H-imidazol-4-yl)ethan-1-amine | CHEMBL544208 |...)
Show SMILES NCCc1cnc[nH]1
Show InChI InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)
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MCE
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Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by PDSP Ki Database




J Pharmacol Exp Ther 311: 274-81 (2004)


Article DOI: 10.1124/jpet.104.070086
BindingDB Entry DOI: 10.7270/Q27S7MB9
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%