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PubMed code 15189042

Compile data set for download or QSAR
Found 24 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Amine oxidase [flavin-containing] B


(Rattus norvegicus (rat))		BDBM50148822
PNG
(5-Ethyl-4-p-tolyl-5H-pyridazino[4,3-b]indol-3-ylam...)
Show SMILES CCn1c2ccccc2c2nnc(N)c(-c3ccc(C)cc3)c12
Show InChI InChI=1S/C19H18N4/c1-3-23-15-7-5-4-6-14(15)17-18(23)16(19(20)22-21-17)13-10-8-12(2)9-11-13/h4-11H,3H2,1-2H3,(H2,20,22)
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n/an/a 1.10E+4n/an/an/an/an/an/a



Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Monoamine oxidase B from rat liver mitochondria

J Med Chem 47: 3455-61 (2004)


Article DOI: 10.1021/jm030479g
BindingDB Entry DOI: 10.7270/Q26H4GWM
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50148810
PNG
(4-(4-Isopropyl-phenyl)-5-methyl-5H-pyridazino[4,3-...)
Show SMILES CC(C)c1ccc(cc1)-c1c(N)nnc2c3ccccc3n(C)c12
Show InChI InChI=1S/C20H20N4/c1-12(2)13-8-10-14(11-9-13)17-19-18(22-23-20(17)21)15-6-4-5-7-16(15)24(19)3/h4-12H,1-3H3,(H2,21,23)
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n/an/a 1.41E+4n/an/an/an/an/an/a



Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Monoamine oxidase A from rat liver mitochondria

J Med Chem 47: 3455-61 (2004)


Article DOI: 10.1021/jm030479g
BindingDB Entry DOI: 10.7270/Q26H4GWM
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Rattus norvegicus (rat))		BDBM50148821
PNG
(5-Ethyl-4-(4-isopropyl-phenyl)-5H-pyridazino[4,3-b...)
Show SMILES CCn1c2ccccc2c2nnc(N)c(-c3ccc(cc3)C(C)C)c12
Show InChI InChI=1S/C21H22N4/c1-4-25-17-8-6-5-7-16(17)19-20(25)18(21(22)24-23-19)15-11-9-14(10-12-15)13(2)3/h5-13H,4H2,1-3H3,(H2,22,24)
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n/an/a 1.58E+4n/an/an/an/an/an/a



Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Monoamine oxidase B from rat liver mitochondria

J Med Chem 47: 3455-61 (2004)


Article DOI: 10.1021/jm030479g
BindingDB Entry DOI: 10.7270/Q26H4GWM
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50148817
PNG
(5-Benzyl-4-(2-chloro-phenyl)-5H-pyridazino[4,3-b]i...)
Show SMILES Nc1nnc2c3ccccc3n(Cc3ccccc3)c2c1-c1ccccc1Cl |(8.52,2.84,;6.99,2.81,;6.14,4.12,;4.61,4.04,;3.89,2.67,;2.42,2.27,;1.12,3.11,;-.25,2.41,;-.33,.9,;.96,.05,;2.33,.74,;3.77,.2,;4.17,-1.29,;3.08,-2.37,;1.61,-1.98,;.52,-3.06,;.92,-4.54,;2.4,-4.94,;3.49,-3.85,;4.73,1.37,;6.27,1.44,;7.1,.14,;6.38,-1.21,;7.19,-2.52,;8.73,-2.45,;9.45,-1.1,;8.64,.2,;9.97,.98,)|
Show InChI InChI=1S/C23H17ClN4/c24-18-12-6-4-10-16(18)20-22-21(26-27-23(20)25)17-11-5-7-13-19(17)28(22)14-15-8-2-1-3-9-15/h1-13H,14H2,(H2,25,27)
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n/an/a 1.78E+4n/an/an/an/an/an/a



Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Monoamine oxidase A from rat liver mitochondria

J Med Chem 47: 3455-61 (2004)


Article DOI: 10.1021/jm030479g
BindingDB Entry DOI: 10.7270/Q26H4GWM
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Rattus norvegicus (rat))		BDBM50148814
PNG
(8-Bromo-4-phenyl-5H-pyridazino[4,3-b]indol-3-ylami...)
Show SMILES Nc1nnc2c3cc(Br)ccc3[nH]c2c1-c1ccccc1
Show InChI InChI=1S/C16H11BrN4/c17-10-6-7-12-11(8-10)14-15(19-12)13(16(18)21-20-14)9-4-2-1-3-5-9/h1-8,19H,(H2,18,21)
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n/an/a 2.51E+4n/an/an/an/an/an/a



Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Monoamine oxidase B from rat liver mitochondria

J Med Chem 47: 3455-61 (2004)


Article DOI: 10.1021/jm030479g
BindingDB Entry DOI: 10.7270/Q26H4GWM
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50148819
PNG
(5-Methyl-4-phenyl-5H-pyridazino[4,3-b]indol-3-ylam...)
Show SMILES Cn1c2ccccc2c2nnc(N)c(-c3ccccc3)c12
Show InChI InChI=1S/C17H14N4/c1-21-13-10-6-5-9-12(13)15-16(21)14(17(18)20-19-15)11-7-3-2-4-8-11/h2-10H,1H3,(H2,18,20)
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n/an/a 2.82E+4n/an/an/an/an/an/a



Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Monoamine oxidase A from rat liver mitochondria

J Med Chem 47: 3455-61 (2004)


Article DOI: 10.1021/jm030479g
BindingDB Entry DOI: 10.7270/Q26H4GWM
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50148811
PNG
(4-p-Tolyl-5H-pyridazino[4,3-b]indol-3-ylamine | CH...)
Show SMILES Cc1ccc(cc1)-c1c(N)nnc2c3ccccc3[nH]c12
Show InChI InChI=1S/C17H14N4/c1-10-6-8-11(9-7-10)14-16-15(20-21-17(14)18)12-4-2-3-5-13(12)19-16/h2-9,19H,1H3,(H2,18,21)
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n/an/a 3.16E+4n/an/an/an/an/an/a



Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Monoamine oxidase A from rat liver mitochondria

J Med Chem 47: 3455-61 (2004)


Article DOI: 10.1021/jm030479g
BindingDB Entry DOI: 10.7270/Q26H4GWM
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Rattus norvegicus (rat))		BDBM50148817
PNG
(5-Benzyl-4-(2-chloro-phenyl)-5H-pyridazino[4,3-b]i...)
Show SMILES Nc1nnc2c3ccccc3n(Cc3ccccc3)c2c1-c1ccccc1Cl |(8.52,2.84,;6.99,2.81,;6.14,4.12,;4.61,4.04,;3.89,2.67,;2.42,2.27,;1.12,3.11,;-.25,2.41,;-.33,.9,;.96,.05,;2.33,.74,;3.77,.2,;4.17,-1.29,;3.08,-2.37,;1.61,-1.98,;.52,-3.06,;.92,-4.54,;2.4,-4.94,;3.49,-3.85,;4.73,1.37,;6.27,1.44,;7.1,.14,;6.38,-1.21,;7.19,-2.52,;8.73,-2.45,;9.45,-1.1,;8.64,.2,;9.97,.98,)|
Show InChI InChI=1S/C23H17ClN4/c24-18-12-6-4-10-16(18)20-22-21(26-27-23(20)25)17-11-5-7-13-19(17)28(22)14-15-8-2-1-3-9-15/h1-13H,14H2,(H2,25,27)
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n/an/a 3.54E+4n/an/an/an/an/an/a



Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Monoamine oxidase B from rat liver mitochondria

J Med Chem 47: 3455-61 (2004)


Article DOI: 10.1021/jm030479g
BindingDB Entry DOI: 10.7270/Q26H4GWM
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Rattus norvegicus (rat))		BDBM50148815
PNG
(4-(2-Fluoro-phenyl)-5-methyl-5H-pyridazino[4,3-b]i...)
Show SMILES Cn1c2ccccc2c2nnc(N)c(-c3ccccc3F)c12 |(4.17,-1.29,;3.77,.2,;2.33,.74,;.96,.05,;-.33,.9,;-.25,2.41,;1.12,3.11,;2.42,2.27,;3.89,2.67,;4.61,4.04,;6.14,4.12,;6.99,2.81,;8.52,2.84,;6.27,1.44,;7.1,.14,;6.38,-1.21,;7.19,-2.52,;8.73,-2.45,;9.45,-1.1,;8.64,.2,;9.97,.98,;4.73,1.37,)|
Show InChI InChI=1S/C17H13FN4/c1-22-13-9-5-3-7-11(13)15-16(22)14(17(19)21-20-15)10-6-2-4-8-12(10)18/h2-9H,1H3,(H2,19,21)
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n/an/a 4.16E+4n/an/an/an/an/an/a



Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Monoamine oxidase B from rat liver mitochondria

J Med Chem 47: 3455-61 (2004)


Article DOI: 10.1021/jm030479g
BindingDB Entry DOI: 10.7270/Q26H4GWM
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50148813
PNG
(8-Bromo-4-(4-isopropyl-phenyl)-5H-pyridazino[4,3-b...)
Show SMILES CC(C)c1ccc(cc1)-c1c(N)nnc2c3cc(Br)ccc3[nH]c12
Show InChI InChI=1S/C19H17BrN4/c1-10(2)11-3-5-12(6-4-11)16-18-17(23-24-19(16)21)14-9-13(20)7-8-15(14)22-18/h3-10,22H,1-2H3,(H2,21,24)
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n/an/a 6.30E+4n/an/an/an/an/an/a



Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Monoamine oxidase A from rat liver mitochondria

J Med Chem 47: 3455-61 (2004)


Article DOI: 10.1021/jm030479g
BindingDB Entry DOI: 10.7270/Q26H4GWM
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50148808
PNG
(4-(3-Bromo-phenyl)-5-methyl-5H-pyridazino[4,3-b]in...)
Show SMILES Cn1c2ccccc2c2nnc(N)c(-c3cccc(Br)c3)c12
Show InChI InChI=1S/C17H13BrN4/c1-22-13-8-3-2-7-12(13)15-16(22)14(17(19)21-20-15)10-5-4-6-11(18)9-10/h2-9H,1H3,(H2,19,21)
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n/an/a 6.31E+4n/an/an/an/an/an/a



Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Monoamine oxidase A from rat liver mitochondria

J Med Chem 47: 3455-61 (2004)


Article DOI: 10.1021/jm030479g
BindingDB Entry DOI: 10.7270/Q26H4GWM
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50148814
PNG
(8-Bromo-4-phenyl-5H-pyridazino[4,3-b]indol-3-ylami...)
Show SMILES Nc1nnc2c3cc(Br)ccc3[nH]c2c1-c1ccccc1
Show InChI InChI=1S/C16H11BrN4/c17-10-6-7-12-11(8-10)14-15(19-12)13(16(18)21-20-14)9-4-2-1-3-5-9/h1-8,19H,(H2,18,21)
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n/an/a 6.31E+4n/an/an/an/an/an/a



Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Monoamine oxidase A from rat liver mitochondria

J Med Chem 47: 3455-61 (2004)


Article DOI: 10.1021/jm030479g
BindingDB Entry DOI: 10.7270/Q26H4GWM
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Rattus norvegicus (rat))		BDBM50148820
PNG
(5-Ethyl-4-phenyl-5H-pyridazino[4,3-b]indol-3-ylami...)
Show SMILES CCn1c2ccccc2c2nnc(N)c(-c3ccccc3)c12
Show InChI InChI=1S/C18H16N4/c1-2-22-14-11-7-6-10-13(14)16-17(22)15(18(19)21-20-16)12-8-4-3-5-9-12/h3-11H,2H2,1H3,(H2,19,21)
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n/an/a 7.20E+4n/an/an/an/an/an/a



Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Monoamine oxidase B from rat liver mitochondria

J Med Chem 47: 3455-61 (2004)


Article DOI: 10.1021/jm030479g
BindingDB Entry DOI: 10.7270/Q26H4GWM
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Rattus norvegicus (rat))		BDBM50148813
PNG
(8-Bromo-4-(4-isopropyl-phenyl)-5H-pyridazino[4,3-b...)
Show SMILES CC(C)c1ccc(cc1)-c1c(N)nnc2c3cc(Br)ccc3[nH]c12
Show InChI InChI=1S/C19H17BrN4/c1-10(2)11-3-5-12(6-4-11)16-18-17(23-24-19(16)21)14-9-13(20)7-8-15(14)22-18/h3-10,22H,1-2H3,(H2,21,24)
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n/an/a 7.90E+4n/an/an/an/an/an/a



Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Monoamine oxidase B from rat liver mitochondria

J Med Chem 47: 3455-61 (2004)


Article DOI: 10.1021/jm030479g
BindingDB Entry DOI: 10.7270/Q26H4GWM
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50148812
PNG
(4-(4-Dimethylamino-phenyl)-5H-pyridazino[4,3-b]ind...)
Show SMILES CN(C)c1ccc(cc1)-c1c(N)nnc2c3ccccc3[nH]c12
Show InChI InChI=1S/C18H17N5/c1-23(2)12-9-7-11(8-10-12)15-17-16(21-22-18(15)19)13-5-3-4-6-14(13)20-17/h3-10,20H,1-2H3,(H2,19,22)
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n/an/a 7.94E+4n/an/an/an/an/an/a



Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Monoamine oxidase A from rat liver mitochondria

J Med Chem 47: 3455-61 (2004)


Article DOI: 10.1021/jm030479g
BindingDB Entry DOI: 10.7270/Q26H4GWM
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50148821
PNG
(5-Ethyl-4-(4-isopropyl-phenyl)-5H-pyridazino[4,3-b...)
Show SMILES CCn1c2ccccc2c2nnc(N)c(-c3ccc(cc3)C(C)C)c12
Show InChI InChI=1S/C21H22N4/c1-4-25-17-8-6-5-7-16(17)19-20(25)18(21(22)24-23-19)15-11-9-14(10-12-15)13(2)3/h5-13H,4H2,1-3H3,(H2,22,24)
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n/an/a 1.00E+5n/an/an/an/an/an/a



Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Monoamine oxidase A from rat liver mitochondria

J Med Chem 47: 3455-61 (2004)


Article DOI: 10.1021/jm030479g
BindingDB Entry DOI: 10.7270/Q26H4GWM
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Rattus norvegicus (rat))		BDBM50148808
PNG
(4-(3-Bromo-phenyl)-5-methyl-5H-pyridazino[4,3-b]in...)
Show SMILES Cn1c2ccccc2c2nnc(N)c(-c3cccc(Br)c3)c12
Show InChI InChI=1S/C17H13BrN4/c1-22-13-8-3-2-7-12(13)15-16(22)14(17(19)21-20-15)10-5-4-6-11(18)9-10/h2-9H,1H3,(H2,19,21)
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n/an/a 1.00E+5n/an/an/an/an/an/a



Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Monoamine oxidase B from rat liver mitochondria

J Med Chem 47: 3455-61 (2004)


Article DOI: 10.1021/jm030479g
BindingDB Entry DOI: 10.7270/Q26H4GWM
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Rattus norvegicus (rat))		BDBM50148811
PNG
(4-p-Tolyl-5H-pyridazino[4,3-b]indol-3-ylamine | CH...)
Show SMILES Cc1ccc(cc1)-c1c(N)nnc2c3ccccc3[nH]c12
Show InChI InChI=1S/C17H14N4/c1-10-6-8-11(9-7-10)14-16-15(20-21-17(14)18)12-4-2-3-5-13(12)19-16/h2-9,19H,1H3,(H2,18,21)
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n/an/a 1.58E+5n/an/an/an/an/an/a



Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Monoamine oxidase B from rat liver mitochondria

J Med Chem 47: 3455-61 (2004)


Article DOI: 10.1021/jm030479g
BindingDB Entry DOI: 10.7270/Q26H4GWM
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Rattus norvegicus (rat))		BDBM50148810
PNG
(4-(4-Isopropyl-phenyl)-5-methyl-5H-pyridazino[4,3-...)
Show SMILES CC(C)c1ccc(cc1)-c1c(N)nnc2c3ccccc3n(C)c12
Show InChI InChI=1S/C20H20N4/c1-12(2)13-8-10-14(11-9-13)17-19-18(22-23-20(17)21)15-6-4-5-7-16(15)24(19)3/h4-12H,1-3H3,(H2,21,23)
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n/an/a 3.16E+5n/an/an/an/an/an/a



Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Monoamine oxidase B from rat liver mitochondria

J Med Chem 47: 3455-61 (2004)


Article DOI: 10.1021/jm030479g
BindingDB Entry DOI: 10.7270/Q26H4GWM
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50148809
PNG
(4-(2-Chloro-phenyl)-5H-pyridazino[4,3-b]indol-3-yl...)
Show SMILES Nc1nnc2c3ccccc3[nH]c2c1-c1ccccc1Cl |(8.52,2.84,;6.99,2.81,;6.14,4.12,;4.61,4.04,;3.89,2.67,;2.42,2.27,;1.12,3.11,;-.25,2.41,;-.33,.9,;.96,.05,;2.33,.74,;3.77,.2,;4.73,1.37,;6.27,1.44,;7.1,.14,;8.64,.2,;9.45,-1.1,;8.73,-2.45,;7.19,-2.52,;6.38,-1.21,;4.84,-1.26,)|
Show InChI InChI=1S/C16H11ClN4/c17-11-7-3-1-5-9(11)13-15-14(20-21-16(13)18)10-6-2-4-8-12(10)19-15/h1-8,19H,(H2,18,21)
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PubMed
n/an/a 3.16E+5n/an/an/an/an/an/a



Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Monoamine oxidase A from rat liver mitochondria

J Med Chem 47: 3455-61 (2004)


Article DOI: 10.1021/jm030479g
BindingDB Entry DOI: 10.7270/Q26H4GWM
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50148816
PNG
(4-(2-Fluoro-phenyl)-5H-pyridazino[4,3-b]indol-3-yl...)
Show SMILES Nc1nnc2c3ccccc3[nH]c2c1-c1ccccc1F |(8.52,2.84,;6.99,2.81,;6.14,4.12,;4.61,4.04,;3.89,2.67,;2.42,2.27,;1.12,3.11,;-.25,2.41,;-.33,.9,;.96,.05,;2.33,.74,;3.77,.2,;4.73,1.37,;6.27,1.44,;7.1,.14,;8.64,.2,;9.45,-1.1,;8.73,-2.45,;7.19,-2.52,;6.38,-1.21,;4.84,-1.26,)|
Show InChI InChI=1S/C16H11FN4/c17-11-7-3-1-5-9(11)13-15-14(20-21-16(13)18)10-6-2-4-8-12(10)19-15/h1-8,19H,(H2,18,21)
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PubMed
n/an/a 6.31E+5n/an/an/an/an/an/a



Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Monoamine oxidase A from rat liver mitochondria

J Med Chem 47: 3455-61 (2004)


Article DOI: 10.1021/jm030479g
BindingDB Entry DOI: 10.7270/Q26H4GWM
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Rattus norvegicus (rat))		BDBM50148818
PNG
(4-(4-Isopropyl-phenyl)-5H-pyridazino[4,3-b]indol-3...)
Show SMILES CC(C)c1ccc(cc1)-c1c(N)nnc2c3ccccc3[nH]c12
Show InChI InChI=1S/C19H18N4/c1-11(2)12-7-9-13(10-8-12)16-18-17(22-23-19(16)20)14-5-3-4-6-15(14)21-18/h3-11,21H,1-2H3,(H2,20,23)
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n/an/a>1.00E+6n/an/an/an/an/an/a



Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Monoamine oxidase B from rat liver mitochondria

J Med Chem 47: 3455-61 (2004)


Article DOI: 10.1021/jm030479g
BindingDB Entry DOI: 10.7270/Q26H4GWM
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50148818
PNG
(4-(4-Isopropyl-phenyl)-5H-pyridazino[4,3-b]indol-3...)
Show SMILES CC(C)c1ccc(cc1)-c1c(N)nnc2c3ccccc3[nH]c12
Show InChI InChI=1S/C19H18N4/c1-11(2)12-7-9-13(10-8-12)16-18-17(22-23-19(16)20)14-5-3-4-6-15(14)21-18/h3-11,21H,1-2H3,(H2,20,23)
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PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Monoamine oxidase A from rat liver mitochondria

J Med Chem 47: 3455-61 (2004)


Article DOI: 10.1021/jm030479g
BindingDB Entry DOI: 10.7270/Q26H4GWM
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Rattus norvegicus (rat))		BDBM50148823
PNG
(5-(2-Dimethylamino-ethyl)-4-(4-isopropyl-phenyl)-5...)
Show SMILES CC(C)c1ccc(cc1)-c1c(N)nnc2c3ccccc3n(CCN(C)C)c12
Show InChI InChI=1S/C23H27N5/c1-15(2)16-9-11-17(12-10-16)20-22-21(25-26-23(20)24)18-7-5-6-8-19(18)28(22)14-13-27(3)4/h5-12,15H,13-14H2,1-4H3,(H2,24,26)
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PubMed
n/an/a 1.00E+6n/an/an/an/an/an/a



Russian Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Monoamine oxidase A from rat liver mitochondria

J Med Chem 47: 3455-61 (2004)


Article DOI: 10.1021/jm030479g
BindingDB Entry DOI: 10.7270/Q26H4GWM
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%