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PubMed code 15225709

Compile data set for download or QSAR
Found 37 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9835
PNG
(1-[(5S)-5-[(4-aminobenzene)(3-methylbutyl)sulfonam...)
Show SMILES CC(C)CCN([C@H](CO)CCCCNC(=O)N(Cc1cccs1)Cc1ccc2OCOc2c1)S(=O)(=O)c1ccc(N)cc1 |r|
Show InChI InChI=1S/C31H42N4O6S2/c1-23(2)14-16-35(43(38,39)28-11-9-25(32)10-12-28)26(21-36)6-3-4-15-33-31(37)34(20-27-7-5-17-42-27)19-24-8-13-29-30(18-24)41-22-40-29/h5,7-13,17-18,23,26,36H,3-4,6,14-16,19-22,32H2,1-2H3,(H,33,37)/t26-/m0/s1
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 1.40n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9831
PNG
(1-[(5S)-5-[(4-aminobenzene)(2-methylpropyl)sulfona...)
Show SMILES CC(C)CN([C@H](CO)CCCCNC(=O)N(Cc1ccc2OCOc2c1)Cc1ccc2OCOc2c1)S(=O)(=O)c1ccc(N)cc1 |r|
Show InChI InChI=1S/C33H42N4O8S/c1-23(2)17-37(46(40,41)28-10-8-26(34)9-11-28)27(20-38)5-3-4-14-35-33(39)36(18-24-6-12-29-31(15-24)44-21-42-29)19-25-7-13-30-32(16-25)45-22-43-30/h6-13,15-16,23,27,38H,3-5,14,17-22,34H2,1-2H3,(H,35,39)/t27-/m0/s1
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 1.70n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9827
PNG
(3-[(5S)-5-[(4-aminobenzene)(2-methylpropyl)sulfona...)
Show SMILES CC(C)CN([C@H](CO)CCCCNC(=O)N(Cc1ccc(cc1)N(=O)=O)Cc1ccc2OCOc2c1)S(=O)(=O)c1ccc(N)cc1 |r|
Show InChI InChI=1S/C32H41N5O8S/c1-23(2)18-36(46(42,43)29-13-9-26(33)10-14-29)28(21-38)5-3-4-16-34-32(39)35(19-24-6-11-27(12-7-24)37(40)41)20-25-8-15-30-31(17-25)45-22-44-30/h6-15,17,23,28,38H,3-5,16,18-22,33H2,1-2H3,(H,34,39)/t28-/m0/s1
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 2n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9825
PNG
(1-[(5S)-5-[(4-aminobenzene)(2-methylpropyl)sulfona...)
Show SMILES CC(C)CN([C@H](CO)CCCCNC(=O)N(Cc1cccs1)Cc1ccc2OCOc2c1)S(=O)(=O)c1ccc(N)cc1 |r|
Show InChI InChI=1S/C30H40N4O6S2/c1-22(2)17-34(42(37,38)27-11-9-24(31)10-12-27)25(20-35)6-3-4-14-32-30(36)33(19-26-7-5-15-41-26)18-23-8-13-28-29(16-23)40-21-39-28/h5,7-13,15-16,22,25,35H,3-4,6,14,17-21,31H2,1-2H3,(H,32,36)/t25-/m0/s1
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 2n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9828
PNG
(3-[(5S)-5-[(4-aminobenzene)(2-methylpropyl)sulfona...)
Show SMILES CC(C)CN([C@H](CO)CCCCNC(=O)N(Cc1ccc(F)cc1)Cc1ccc2OCOc2c1)S(=O)(=O)c1ccc(N)cc1 |r|
Show InChI InChI=1S/C32H41FN4O6S/c1-23(2)18-37(44(40,41)29-13-11-27(34)12-14-29)28(21-38)5-3-4-16-35-32(39)36(19-24-6-9-26(33)10-7-24)20-25-8-15-30-31(17-25)43-22-42-30/h6-15,17,23,28,38H,3-5,16,18-22,34H2,1-2H3,(H,35,39)/t28-/m0/s1
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 2n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9830
PNG
(3-[(5S)-5-[(4-aminobenzene)(2-methylpropyl)sulfona...)
Show SMILES COc1ccc(CN(Cc2ccc3OCOc3c2)C(=O)NCCCC[C@@H](CO)N(CC(C)C)S(=O)(=O)c2ccc(N)cc2)cc1 |r|
Show InChI InChI=1S/C33H44N4O7S/c1-24(2)19-37(45(40,41)30-14-10-27(34)11-15-30)28(22-38)6-4-5-17-35-33(39)36(20-25-7-12-29(42-3)13-8-25)21-26-9-16-31-32(18-26)44-23-43-31/h7-16,18,24,28,38H,4-6,17,19-23,34H2,1-3H3,(H,35,39)/t28-/m0/s1
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 2.20n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9836
PNG
(3-[(5S)-5-[(4-aminobenzene)(3-methylbutyl)sulfonam...)
Show SMILES CC(C)CCN([C@H](CO)CCCCNC(=O)N(Cc1ccc(cc1)N(=O)=O)Cc1ccc2OCOc2c1)S(=O)(=O)c1ccc(N)cc1 |r|
Show InChI InChI=1S/C33H43N5O8S/c1-24(2)16-18-37(47(43,44)30-13-9-27(34)10-14-30)29(22-39)5-3-4-17-35-33(40)36(20-25-6-11-28(12-7-25)38(41)42)21-26-8-15-31-32(19-26)46-23-45-31/h6-15,19,24,29,39H,3-5,16-18,20-23,34H2,1-2H3,(H,35,40)/t29-/m0/s1
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 2.20n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9840
PNG
(3-[(5S)-5-[(4-aminobenzene)(3-methylbutyl)sulfonam...)
Show SMILES COc1cccc(CN(Cc2ccc3OCOc3c2)C(=O)NCCCC[C@@H](CO)N(CCC(C)C)S(=O)(=O)c2ccc(N)cc2)c1 |r|
Show InChI InChI=1S/C34H46N4O7S/c1-25(2)16-18-38(46(41,42)31-13-11-28(35)12-14-31)29(23-39)8-4-5-17-36-34(40)37(21-26-7-6-9-30(19-26)43-3)22-27-10-15-32-33(20-27)45-24-44-32/h6-7,9-15,19-20,25,29,39H,4-5,8,16-18,21-24,35H2,1-3H3,(H,36,40)/t29-/m0/s1
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 2.20n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9829
PNG
(3-[(5S)-5-[(4-aminobenzene)(2-methylpropyl)sulfona...)
Show SMILES CC(C)CN([C@H](CO)CCCCNC(=O)N(Cc1ccc(cc1)C(F)(F)F)Cc1ccc2OCOc2c1)S(=O)(=O)c1ccc(N)cc1 |r|
Show InChI InChI=1S/C33H41F3N4O6S/c1-23(2)18-40(47(43,44)29-13-11-27(37)12-14-29)28(21-41)5-3-4-16-38-32(42)39(19-24-6-9-26(10-7-24)33(34,35)36)20-25-8-15-30-31(17-25)46-22-45-30/h6-15,17,23,28,41H,3-5,16,18-22,37H2,1-2H3,(H,38,42)/t28-/m0/s1
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 2.5n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9841
PNG
(3-[(5S)-5-[(4-aminobenzene)(3-methylbutyl)sulfonam...)
Show SMILES COc1cccc(CN(Cc2ccc3OCOc3c2)C(=S)NCCCC[C@@H](CO)N(CCC(C)C)S(=O)(=O)c2ccc(N)cc2)c1 |r|
Show InChI InChI=1S/C34H46N4O6S2/c1-25(2)16-18-38(46(40,41)31-13-11-28(35)12-14-31)29(23-39)8-4-5-17-36-34(45)37(21-26-7-6-9-30(19-26)42-3)22-27-10-15-32-33(20-27)44-24-43-32/h6-7,9-15,19-20,25,29,39H,4-5,8,16-18,21-24,35H2,1-3H3,(H,36,45)/t29-/m0/s1
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 2.60n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9824
PNG
(3-[(5S)-5-[(4-aminobenzene)(2-methylpropyl)sulfona...)
Show SMILES CC(C)CN([C@H](CO)CCCCNC(=O)N(Cc1ccccc1)Cc1ccc2OCOc2c1)S(=O)(=O)c1ccc(N)cc1 |r|
Show InChI InChI=1S/C32H42N4O6S/c1-24(2)19-36(43(39,40)29-14-12-27(33)13-15-29)28(22-37)10-6-7-17-34-32(38)35(20-25-8-4-3-5-9-25)21-26-11-16-30-31(18-26)42-23-41-30/h3-5,8-9,11-16,18,24,28,37H,6-7,10,17,19-23,33H2,1-2H3,(H,34,38)/t28-/m0/s1
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 2.60n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9839
PNG
(3-[(5S)-5-[(4-aminobenzene)(3-methylbutyl)sulfonam...)
Show SMILES COc1ccc(CN(Cc2ccc3OCOc3c2)C(=O)NCCCC[C@@H](CO)N(CCC(C)C)S(=O)(=O)c2ccc(N)cc2)cc1 |r|
Show InChI InChI=1S/C34H46N4O7S/c1-25(2)17-19-38(46(41,42)31-14-10-28(35)11-15-31)29(23-39)6-4-5-18-36-34(40)37(21-26-7-12-30(43-3)13-8-26)22-27-9-16-32-33(20-27)45-24-44-32/h7-16,20,25,29,39H,4-6,17-19,21-24,35H2,1-3H3,(H,36,40)/t29-/m0/s1
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 2.90n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9845
PNG
(3-[(5S)-5-[(4-aminobenzene)(3-methylbutyl)sulfonam...)
Show SMILES COc1ccc(CN(Cc2ccc3OCOc3c2)C(=S)NCCCC[C@@H](CO)N(CCC(C)C)S(=O)(=O)c2ccc(N)cc2)cc1OC |r|
Show InChI InChI=1S/C35H48N4O7S2/c1-25(2)16-18-39(48(41,42)30-12-10-28(36)11-13-30)29(23-40)7-5-6-17-37-35(47)38(21-26-8-14-31(43-3)33(19-26)44-4)22-27-9-15-32-34(20-27)46-24-45-32/h8-15,19-20,25,29,40H,5-7,16-18,21-24,36H2,1-4H3,(H,37,47)/t29-/m0/s1
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 2.90n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9838
PNG
(3-[(5S)-5-[(4-aminobenzene)(3-methylbutyl)sulfonam...)
Show SMILES CC(C)CCN([C@H](CO)CCCCNC(=O)N(Cc1ccc(cc1)C(F)(F)F)Cc1ccc2OCOc2c1)S(=O)(=O)c1ccc(N)cc1 |r|
Show InChI InChI=1S/C34H43F3N4O6S/c1-24(2)16-18-41(48(44,45)30-13-11-28(38)12-14-30)29(22-42)5-3-4-17-39-33(43)40(20-25-6-9-27(10-7-25)34(35,36)37)21-26-8-15-31-32(19-26)47-23-46-31/h6-15,19,24,29,42H,3-5,16-18,20-23,38H2,1-2H3,(H,39,43)/t29-/m0/s1
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 3n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9844
PNG
(3-[(5S)-5-[(4-aminobenzene)(3-methylbutyl)sulfonam...)
Show SMILES COc1ccc(CN(Cc2ccc3OCOc3c2)C(=O)NCCCC[C@@H](CO)N(CCC(C)C)S(=O)(=O)c2ccc(N)cc2)cc1OC |r|
Show InChI InChI=1S/C35H48N4O8S/c1-25(2)16-18-39(48(42,43)30-12-10-28(36)11-13-30)29(23-40)7-5-6-17-37-35(41)38(21-26-8-14-31(44-3)33(19-26)45-4)22-27-9-15-32-34(20-27)47-24-46-32/h8-15,19-20,25,29,40H,5-7,16-18,21-24,36H2,1-4H3,(H,37,41)/t29-/m0/s1
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 3n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9823
PNG
(3-[(5S)-5-[(4-aminobenzene)(2-methylpropyl)sulfona...)
Show SMILES CC(C)CN([C@H](CO)CCCCNC(=O)N(Cc1ccccc1)Cc1ccc(F)cc1)S(=O)(=O)c1ccc(N)cc1 |r|
Show InChI InChI=1S/C31H41FN4O4S/c1-24(2)20-36(41(39,40)30-17-15-28(33)16-18-30)29(23-37)10-6-7-19-34-31(38)35(21-25-8-4-3-5-9-25)22-26-11-13-27(32)14-12-26/h3-5,8-9,11-18,24,29,37H,6-7,10,19-23,33H2,1-2H3,(H,34,38)/t29-/m0/s1
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 3.30n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9843
PNG
(3-[(5S)-5-[(4-aminobenzene)(3-methylbutyl)sulfonam...)
Show SMILES COc1ccc(CN(Cc2ccc3OCOc3c2)C(=S)NCCCC[C@@H](CO)N(CCC(C)C)S(=O)(=O)c2ccc(N)cc2)cc1 |r|
Show InChI InChI=1S/C34H46N4O6S2/c1-25(2)17-19-38(46(40,41)31-14-10-28(35)11-15-31)29(23-39)6-4-5-18-36-34(45)37(21-26-7-12-30(42-3)13-8-26)22-27-9-16-32-33(20-27)44-24-43-32/h7-16,20,25,29,39H,4-6,17-19,21-24,35H2,1-3H3,(H,36,45)/t29-/m0/s1
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 3.60n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9814
PNG
((2S)-6-{[benzyl(pyridin-4-ylmethyl)carbamoyl]amino...)
Show SMILES CC(C)CN([C@@H](CCCCNC(=O)N(Cc1ccccc1)Cc1ccncc1)C(O)=O)S(=O)(=O)c1ccc(C)cc1 |r|
Show InChI InChI=1S/C31H40N4O5S/c1-24(2)21-35(41(39,40)28-14-12-25(3)13-15-28)29(30(36)37)11-7-8-18-33-31(38)34(22-26-9-5-4-6-10-26)23-27-16-19-32-20-17-27/h4-6,9-10,12-17,19-20,24,29H,7-8,11,18,21-23H2,1-3H3,(H,33,38)(H,36,37)/t29-/m0/s1
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 3.70 -48.9n/an/an/an/an/a4.730



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9833
PNG
(3-[(5S)-5-[(4-aminobenzene)(3-methylbutyl)sulfonam...)
Show SMILES CC(C)CCN([C@H](CO)CCCCNC(=O)N(Cc1ccccc1)Cc1cccc2OCOc12)S(=O)(=O)c1ccc(N)cc1 |r|
Show InChI InChI=1S/C33H44N4O6S/c1-25(2)18-20-37(44(40,41)30-16-14-28(34)15-17-30)29(23-38)12-6-7-19-35-33(39)36(21-26-9-4-3-5-10-26)22-27-11-8-13-31-32(27)43-24-42-31/h3-5,8-11,13-17,25,29,38H,6-7,12,18-24,34H2,1-2H3,(H,35,39)/t29-/m0/s1
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 4n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9834
PNG
(3-[(5S)-5-[(4-aminobenzene)(3-methylbutyl)sulfonam...)
Show SMILES CC(C)CCN([C@H](CO)CCCCNC(=O)N(Cc1ccccc1)Cc1ccc2OCOc2c1)S(=O)(=O)c1ccc(N)cc1 |r|
Show InChI InChI=1S/C33H44N4O6S/c1-25(2)17-19-37(44(40,41)30-14-12-28(34)13-15-30)29(23-38)10-6-7-18-35-33(39)36(21-26-8-4-3-5-9-26)22-27-11-16-31-32(20-27)43-24-42-31/h3-5,8-9,11-16,20,25,29,38H,6-7,10,17-19,21-24,34H2,1-2H3,(H,35,39)/t29-/m0/s1
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 4.10n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9837
PNG
(3-[(5S)-5-[(4-aminobenzene)(3-methylbutyl)sulfonam...)
Show SMILES CC(C)CCN([C@H](CO)CCCCNC(=O)N(Cc1ccc(F)cc1)Cc1ccc2OCOc2c1)S(=O)(=O)c1ccc(N)cc1 |r|
Show InChI InChI=1S/C33H43FN4O6S/c1-24(2)16-18-38(45(41,42)30-13-11-28(35)12-14-30)29(22-39)5-3-4-17-36-33(40)37(20-25-6-9-27(34)10-7-25)21-26-8-15-31-32(19-26)44-23-43-31/h6-15,19,24,29,39H,3-5,16-18,20-23,35H2,1-2H3,(H,36,40)/t29-/m0/s1
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 4.90n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9846
PNG
(3-[(5S)-5-[(4-aminobenzene)(3-methylbutyl)sulfonam...)
Show SMILES CC(C)CCN([C@H](CO)CCCCNC(=O)N(Cc1ccc(F)cc1)Cc1ccc2OCCOc2c1)S(=O)(=O)c1ccc(N)cc1 |r|
Show InChI InChI=1S/C34H45FN4O6S/c1-25(2)16-18-39(46(42,43)31-13-11-29(36)12-14-31)30(24-40)5-3-4-17-37-34(41)38(22-26-6-9-28(35)10-7-26)23-27-8-15-32-33(21-27)45-20-19-44-32/h6-15,21,25,30,40H,3-5,16-20,22-24,36H2,1-2H3,(H,37,41)/t30-/m0/s1
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 5.40n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9821
PNG
(3-[(5S)-5-[(4-aminobenzene)(2-methylpropyl)sulfona...)
Show SMILES CC(C)CN([C@H](CO)CCCCNC(=O)N(Cc1ccccc1)Cc1cccc2OCOc12)S(=O)(=O)c1ccc(N)cc1 |r|
Show InChI InChI=1S/C32H42N4O6S/c1-24(2)19-36(43(39,40)29-16-14-27(33)15-17-29)28(22-37)12-6-7-18-34-32(38)35(20-25-9-4-3-5-10-25)21-26-11-8-13-30-31(26)42-23-41-30/h3-5,8-11,13-17,24,28,37H,6-7,12,18-23,33H2,1-2H3,(H,34,38)/t28-/m0/s1
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 5.40n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9832
PNG
(3-[(5S)-5-[(4-aminobenzene)(3-methylbutyl)sulfonam...)
Show SMILES CC(C)CCN([C@H](CO)CCCCNC(=O)N(Cc1ccccc1)Cc1ccccc1)S(=O)(=O)c1ccc(N)cc1 |r|
Show InChI InChI=1S/C32H44N4O4S/c1-26(2)20-22-36(41(39,40)31-18-16-29(33)17-19-31)30(25-37)15-9-10-21-34-32(38)35(23-27-11-5-3-6-12-27)24-28-13-7-4-8-14-28/h3-8,11-14,16-19,26,30,37H,9-10,15,20-25,33H2,1-2H3,(H,34,38)/t30-/m0/s1
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 5.80n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9826
PNG
(1-[(5S)-5-[(4-aminobenzene)(2-methylpropyl)sulfona...)
Show SMILES CC(C)CN([C@H](CO)CCCCNC(=O)N(Cc1ccsc1)Cc1ccc2OCOc2c1)S(=O)(=O)c1ccc(N)cc1 |r|
Show InChI InChI=1S/C30H40N4O6S2/c1-22(2)16-34(42(37,38)27-9-7-25(31)8-10-27)26(19-35)5-3-4-13-32-30(36)33(18-24-12-14-41-20-24)17-23-6-11-28-29(15-23)40-21-39-28/h6-12,14-15,20,22,26,35H,3-5,13,16-19,21,31H2,1-2H3,(H,32,36)/t26-/m0/s1
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 6.30n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9847
PNG
(3-[(5S)-5-[(4-aminobenzene)(3-methylbutyl)sulfonam...)
Show SMILES CC(C)CCN([C@H](CO)CCCCNC(=S)N(Cc1ccc(F)cc1)Cc1ccc2OCCOc2c1)S(=O)(=O)c1ccc(N)cc1 |r|
Show InChI InChI=1S/C34H45FN4O5S2/c1-25(2)16-18-39(46(41,42)31-13-11-29(36)12-14-31)30(24-40)5-3-4-17-37-34(45)38(22-26-6-9-28(35)10-7-26)23-27-8-15-32-33(21-27)44-20-19-43-32/h6-15,21,25,30,40H,3-5,16-20,22-24,36H2,1-2H3,(H,37,45)/t30-/m0/s1
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 9.90n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9820
PNG
(3-[(5S)-5-[(4-aminobenzene)(2-methylpropyl)sulfona...)
Show SMILES CC(C)CN([C@H](CO)CCCCNC(=O)N(Cc1cccs1)Cc1ccccc1)S(=O)(=O)c1ccc(N)cc1 |r|
Show InChI InChI=1S/C29H40N4O4S2/c1-23(2)19-33(39(36,37)28-15-13-25(30)14-16-28)26(22-34)11-6-7-17-31-29(35)32(21-27-12-8-18-38-27)20-24-9-4-3-5-10-24/h3-5,8-10,12-16,18,23,26,34H,6-7,11,17,19-22,30H2,1-2H3,(H,31,35)/t26-/m0/s1
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 11 -46.2n/an/an/an/an/a4.730



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9817
PNG
(3-[(5S)-5-[(4-aminobenzene)(2-methylpropyl)sulfona...)
Show SMILES CC(C)CN([C@H](CO)CCCCNC(=O)N(Cc1ccccc1)Cc1ccccc1)S(=O)(=O)c1ccc(N)cc1 |r|
Show InChI InChI=1S/C31H42N4O4S/c1-25(2)21-35(40(38,39)30-18-16-28(32)17-19-30)29(24-36)15-9-10-20-33-31(37)34(22-26-11-5-3-6-12-26)23-27-13-7-4-8-14-27/h3-8,11-14,16-19,25,29,36H,9-10,15,20-24,32H2,1-2H3,(H,33,37)/t29-/m0/s1
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 12 -46.0n/an/an/an/an/a4.730



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9822
PNG
(3-[(5S)-5-[(4-aminobenzene)(2-methylpropyl)sulfona...)
Show SMILES CC(C)CN([C@H](CO)CCCCNC(=O)N(Cc1ccccc1)Cc1ccc(F)cc1F)S(=O)(=O)c1ccc(N)cc1 |r|
Show InChI InChI=1S/C31H40F2N4O4S/c1-23(2)19-37(42(40,41)29-15-13-27(34)14-16-29)28(22-38)10-6-7-17-35-31(39)36(20-24-8-4-3-5-9-24)21-25-11-12-26(32)18-30(25)33/h3-5,8-9,11-16,18,23,28,38H,6-7,10,17,19-22,34H2,1-2H3,(H,35,39)/t28-/m0/s1
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 12n/an/an/an/an/an/an/an/a



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9816
PNG
(1,1-dibenzyl-3-[(5S)-6-hydroxy-5-[(4-methylbenzene...)
Show SMILES CC(C)CN([C@H](CO)CCCCNC(=O)N(Cc1ccccc1)Cc1ccccc1)S(=O)(=O)c1ccc(C)cc1 |r|
Show InChI InChI=1S/C32H43N3O4S/c1-26(2)22-35(40(38,39)31-19-17-27(3)18-20-31)30(25-36)16-10-11-21-33-32(37)34(23-28-12-6-4-7-13-28)24-29-14-8-5-9-15-29/h4-9,12-15,17-20,26,30,36H,10-11,16,21-25H2,1-3H3,(H,33,37)/t30-/m0/s1
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 15 -45.4n/an/an/an/an/a4.730



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9813
PNG
((2S)-6-{[benzyl(propan-2-yl)carbamoyl]amino}-2-[(4...)
Show SMILES CC(C)CN([C@@H](CCCCNC(=O)N(Cc1ccccc1)C(C)C)C(O)=O)S(=O)(=O)c1ccc(C)cc1 |r|
Show InChI InChI=1S/C28H41N3O5S/c1-21(2)19-31(37(35,36)25-16-14-23(5)15-17-25)26(27(32)33)13-9-10-18-29-28(34)30(22(3)4)20-24-11-7-6-8-12-24/h6-8,11-12,14-17,21-22,26H,9-10,13,18-20H2,1-5H3,(H,29,34)(H,32,33)/t26-/m0/s1
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 19 -44.8n/an/an/an/an/a4.730



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9818
PNG
(3-[(5S)-5-[(4-aminobenzene)(2-methylpropyl)sulfona...)
Show SMILES CC(C)CN([C@H](CO)CCCCNC(=O)N(Cc1ccccc1)Cc1cccnc1)S(=O)(=O)c1ccc(N)cc1 |r|
Show InChI InChI=1S/C30H41N5O4S/c1-24(2)20-35(40(38,39)29-15-13-27(31)14-16-29)28(23-36)12-6-7-18-33-30(37)34(21-25-9-4-3-5-10-25)22-26-11-8-17-32-19-26/h3-5,8-11,13-17,19,24,28,36H,6-7,12,18,20-23,31H2,1-2H3,(H,33,37)/t28-/m0/s1
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 34 -43.3n/an/an/an/an/a4.730



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9819
PNG
(3-[(5S)-5-[(4-aminobenzene)(2-methylpropyl)sulfona...)
Show SMILES CC(C)CN([C@H](CO)CCCCNC(=O)N(Cc1ccccc1)Cc1ccncc1)S(=O)(=O)c1ccc(N)cc1 |r|
Show InChI InChI=1S/C30H41N5O4S/c1-24(2)20-35(40(38,39)29-13-11-27(31)12-14-29)28(23-36)10-6-7-17-33-30(37)34(21-25-8-4-3-5-9-25)22-26-15-18-32-19-16-26/h3-5,8-9,11-16,18-19,24,28,36H,6-7,10,17,20-23,31H2,1-2H3,(H,33,37)/t28-/m0/s1
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 90 -40.9n/an/an/an/an/a4.730



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9808
PNG
((2S)-2-[(4-methylbenzene)(2-methylpropyl)sulfonami...)
Show SMILES CC(C)CN([C@@H](CCCCNC(=O)NCCc1ccccc1)C(O)=O)S(=O)(=O)c1ccc(C)cc1 |r|
Show InChI InChI=1S/C26H37N3O5S/c1-20(2)19-29(35(33,34)23-14-12-21(3)13-15-23)24(25(30)31)11-7-8-17-27-26(32)28-18-16-22-9-5-4-6-10-22/h4-6,9-10,12-15,20,24H,7-8,11,16-19H2,1-3H3,(H,30,31)(H2,27,28,32)/t24-/m0/s1
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 204 -38.8n/an/an/an/an/a4.730



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9815
PNG
((2S)-6-{[bis(propan-2-yl)carbamoyl]amino}-2-[(4-me...)
Show SMILES CC(C)CN([C@@H](CCCCNC(=O)N(C(C)C)C(C)C)C(O)=O)S(=O)(=O)c1ccc(C)cc1 |r|
Show InChI InChI=1S/C24H41N3O5S/c1-17(2)16-26(33(31,32)21-13-11-20(7)12-14-21)22(23(28)29)10-8-9-15-25-24(30)27(18(3)4)19(5)6/h11-14,17-19,22H,8-10,15-16H2,1-7H3,(H,25,30)(H,28,29)/t22-/m0/s1
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 300 -37.9n/an/an/an/an/a4.730



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9811
PNG
((2S)-6-{[benzyl(2-phenylethyl)carbamoyl]amino}-2-[...)
Show SMILES CC(C)CN([C@@H](CCCCNC(=O)N(CCc1ccccc1)Cc1ccccc1)C(O)=O)S(=O)(=O)c1ccc(C)cc1 |r|
Show InChI InChI=1S/C33H43N3O5S/c1-26(2)24-36(42(40,41)30-19-17-27(3)18-20-30)31(32(37)38)16-10-11-22-34-33(39)35(25-29-14-8-5-9-15-29)23-21-28-12-6-4-7-13-28/h4-9,12-15,17-20,26,31H,10-11,16,21-25H2,1-3H3,(H,34,39)(H,37,38)/t31-/m0/s1
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>300>-37.9n/an/an/an/an/a4.730



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599]


(Human immunodeficiency virus type 1)		BDBM9809
PNG
((2S)-2-[(4-methylbenzene)(2-methylpropyl)sulfonami...)
Show SMILES CC(C)CN([C@@H](CCCCNC(=O)NCc1ccccn1)C(O)=O)S(=O)(=O)c1ccc(C)cc1 |r|
Show InChI InChI=1S/C24H34N4O5S/c1-18(2)17-28(34(32,33)21-12-10-19(3)11-13-21)22(23(29)30)9-5-7-15-26-24(31)27-16-20-8-4-6-14-25-20/h4,6,8,10-14,18,22H,5,7,9,15-17H2,1-3H3,(H,29,30)(H2,26,27,31)/t22-/m0/s1
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>300>-37.9n/an/an/an/an/a4.730



Procyon Biopharma Inc.



Assay Description
HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...

Bioorg Med Chem Lett 14: 3971-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.049
BindingDB Entry DOI: 10.7270/Q22V2DB2
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%