Search and Browse
Download
Enter Data
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31225 (2-phenoxybenzoyltryptophan derivative, R5C3) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | Purchase PC cid PC sid UniChem Similars | Article PubMed | 100 | -39.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Schering-Plough Research Institute | Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1... | Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31224 (2-phenoxybenzoyltryptophan derivative, R5C2) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 200 | -38.0 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Schering-Plough Research Institute | Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1... | Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31216 (2-phenoxybenzoyltryptophan derivative, R3C2) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 400 | -36.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Schering-Plough Research Institute | Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1... | Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31209 (2-phenoxybenzoyltryptophan derivative, R1C3) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 500 | -35.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Schering-Plough Research Institute | Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1... | Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31220 (2-phenoxybenzoyltryptophan derivative, R4C2) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 600 | -35.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Schering-Plough Research Institute | Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1... | Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31221 (2-phenoxybenzoyltryptophan derivative, R4C3) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 600 | -35.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Schering-Plough Research Institute | Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1... | Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31226 (2-phenoxybenzoyltryptophan derivative, R5C4) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 600 | -35.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Schering-Plough Research Institute | Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1... | Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31213 (2-phenoxybenzoyltryptophan derivative, R2C3) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 600 | -35.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Schering-Plough Research Institute | Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1... | Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31210 (2-phenoxybenzoyltryptophan derivative, R1C4) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 600 | -35.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Schering-Plough Research Institute | Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1... | Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31212 (2-phenoxybenzoyltryptophan derivative, R2C2) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 800 | -34.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Schering-Plough Research Institute | Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1... | Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31217 (2-phenoxybenzoyltryptophan derivative, R3C3) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 800 | -34.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Schering-Plough Research Institute | Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1... | Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31208 (2-phenoxybenzoyltryptophan derivative, R1C2) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 800 | -34.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Schering-Plough Research Institute | Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1... | Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31214 (2-phenoxybenzoyltryptophan derivative, R2C4) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.00E+3 | -34.0 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Schering-Plough Research Institute | Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1... | Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31222 (2-phenoxybenzoyltryptophan derivative, R4C4) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.00E+3 | -34.0 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Schering-Plough Research Institute | Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1... | Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31218 (2-phenoxybenzoyltryptophan derivative, R3C4) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 2.00E+3 | -32.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Schering-Plough Research Institute | Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1... | Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31207 (2-phenoxybenzoyltryptophan derivative, R1C1) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 3.00E+3 | -31.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Schering-Plough Research Institute | Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1... | Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31211 (2-phenoxybenzoyltryptophan derivative, R2C1) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 6.00E+3 | -29.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Schering-Plough Research Institute | Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1... | Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31219 (2-phenoxybenzoyltryptophan derivative, R4C1) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.00E+4 | -28.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Schering-Plough Research Institute | Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1... | Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31223 (2-phenoxybenzoyltryptophan derivative, R5C1) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.00E+4 | -28.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Schering-Plough Research Institute | Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1... | Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM31215 (2-phenoxybenzoyltryptophan derivative, R3C1) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 2.00E+4 | -26.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Schering-Plough Research Institute | Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1... | Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
