Affinity Data by PubMed id=15341479

PubMed code 15341479

Found 36 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50151910 (3-Fluoro-5-(5-pyridin-2-yl-tetrazol-2-yl)-benzonit...) Show SMILES Fc1cc(cc(c1)-n1nnc(n1)-c1ccccn1)C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from glutamate 5 receptor of rat cortical membranes				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50151907 (3-(5-Pyridin-2-yl-tetrazol-2-yl)-benzonitrile \| CH...) Show SMILES N#Cc1cccc(c1)-n1nnc(n1)-c1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from glutamate 5 receptor of rat cortical membranes				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50151904 (3-(2-Pyridin-2-yl-2H-[1,2,3]triazol-4-yl)-benzonit...) Show SMILES N#Cc1cccc(c1)-c1cnn(n1)-c1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from glutamate 5 receptor of rat cortical membranes				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50151901 (3-(4-Pyridin-2-yl-pyrazol-1-yl)-benzonitrile \| CHE...) Show SMILES N#Cc1cccc(c1)-n1cc(cn1)-c1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from glutamate 5 receptor of rat cortical membranes				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50151905 (3-(4-Pyridin-2-yl-[1,2,3]triazol-2-yl)-benzonitril...) Show SMILES N#Cc1cccc(c1)-n1ncc(n1)-c1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from glutamate 5 receptor of rat cortical membranes				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50151906 (3-(2-Pyridin-2-yl-2H-tetrazol-5-yl)-benzonitrile \|...) Show SMILES N#Cc1cccc(c1)-c1nnn(n1)-c1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from glutamate 5 receptor of rat cortical membranes				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50151909 (3-(3-Pyridin-2-yl-[1,2,4]oxadiazol-5-yl)-benzonitr...) Show SMILES N#Cc1cccc(c1)-c1nc(no1)-c1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from glutamate 5 receptor of rat cortical membranes				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50151895 (3-(3-Pyridin-2-yl-pyrazol-1-yl)-benzonitrile \| CHE...) Show SMILES N#Cc1cccc(c1)-n1ccc(n1)-c1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from glutamate 5 receptor of rat cortical membranes				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50151899 (3-(1-Pyridin-2-yl-1H-pyrrol-3-yl)-benzonitrile \| C...) Show SMILES N#Cc1cccc(c1)-c1ccn(c1)-c1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from glutamate 5 receptor of rat cortical membranes				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50151900 (3-(4-Pyridin-2-yl-imidazol-1-yl)-benzonitrile \| CH...) Show SMILES N#Cc1cccc(c1)-n1cnc(c1)-c1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	>600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from glutamate 5 receptor of rat cortical membranes				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50151896 (3-(1-Pyridin-2-yl-1H-[1,2,4]triazol-3-yl)-benzonit...) Show SMILES N#Cc1cccc(c1)-c1ncn(n1)-c1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from glutamate 5 receptor of rat cortical membranes				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50151902 (3-(1-Pyridin-2-yl-1H-pyrazol-3-yl)-benzonitrile \| ...) Show SMILES N#Cc1cccc(c1)-c1ccn(n1)-c1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	>600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from glutamate 5 receptor of rat cortical membranes				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50151898 (3-(3-Pyridin-2-yl-[1,2,4]triazol-1-yl)-benzonitril...) Show SMILES N#Cc1cccc(c1)-n1cnc(n1)-c1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from glutamate 5 receptor of rat cortical membranes				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50151903 (3-(4-Pyridin-2-yl-[1,2,3]triazol-1-yl)-benzonitril...) Show SMILES N#Cc1cccc(c1)-n1cc(nn1)-c1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from glutamate 5 receptor of rat cortical membranes				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50151897 (3-(3-Pyridin-2-yl-pyrrol-1-yl)-benzonitrile \| CHEM...) Show SMILES N#Cc1cccc(c1)-n1ccc(c1)-c1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from glutamate 5 receptor of rat cortical membranes				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50151908 (3-(1-Pyridin-2-yl-1H-imidazol-4-yl)-benzonitrile \|...) Show SMILES N#Cc1cccc(c1)-c1cn(cn1)-c1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	>600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from glutamate 5 receptor of rat cortical membranes				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50151911 (3-(1-Pyridin-2-yl-1H-[1,2,3]triazol-4-yl)-benzonit...) Show SMILES N#Cc1cccc(c1)-c1cn(nn1)-c1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from glutamate 5 receptor of rat cortical membranes				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50151912 (3-(1-Pyridin-2-yl-1H-pyrazol-4-yl)-benzonitrile \| ...) Show SMILES N#Cc1cccc(c1)-c1cnn(c1)-c1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from glutamate 5 receptor of rat cortical membranes				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50151910 (3-Fluoro-5-(5-pyridin-2-yl-tetrazol-2-yl)-benzonit...) Show SMILES Fc1cc(cc(c1)-n1nnc(n1)-c1ccccn1)C#N Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration towards human glutamate receptor 5 in calcium flux assay				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50151907 (3-(5-Pyridin-2-yl-tetrazol-2-yl)-benzonitrile \| CH...) Show SMILES N#Cc1cccc(c1)-n1nnc(n1)-c1ccccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration towards human glutamate receptor 5 in calcium flux assay				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50151905 (3-(4-Pyridin-2-yl-[1,2,3]triazol-2-yl)-benzonitril...) Show SMILES N#Cc1cccc(c1)-n1ncc(n1)-c1ccccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration towards human glutamate receptor 5 in calcium flux assay				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50151909 (3-(3-Pyridin-2-yl-[1,2,4]oxadiazol-5-yl)-benzonitr...) Show SMILES N#Cc1cccc(c1)-c1nc(no1)-c1ccccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration towards human glutamate receptor 5 in calcium flux assay				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50151901 (3-(4-Pyridin-2-yl-pyrazol-1-yl)-benzonitrile \| CHE...) Show SMILES N#Cc1cccc(c1)-n1cc(cn1)-c1ccccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration towards human glutamate receptor 5 in calcium flux assay				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50151897 (3-(3-Pyridin-2-yl-pyrrol-1-yl)-benzonitrile \| CHEM...) Show SMILES N#Cc1cccc(c1)-n1ccc(c1)-c1ccccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration towards human glutamate receptor 5 in calcium flux assay				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50151904 (3-(2-Pyridin-2-yl-2H-[1,2,3]triazol-4-yl)-benzonit...) Show SMILES N#Cc1cccc(c1)-c1cnn(n1)-c1ccccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration towards human glutamate receptor 5 in calcium flux assay				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50151906 (3-(2-Pyridin-2-yl-2H-tetrazol-5-yl)-benzonitrile \|...) Show SMILES N#Cc1cccc(c1)-c1nnn(n1)-c1ccccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration towards human glutamate receptor 5 in calcium flux assay				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50151895 (3-(3-Pyridin-2-yl-pyrazol-1-yl)-benzonitrile \| CHE...) Show SMILES N#Cc1cccc(c1)-n1ccc(n1)-c1ccccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration towards human glutamate receptor 5 in calcium flux assay				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50151898 (3-(3-Pyridin-2-yl-[1,2,4]triazol-1-yl)-benzonitril...) Show SMILES N#Cc1cccc(c1)-n1cnc(n1)-c1ccccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration towards human glutamate receptor 5 in calcium flux assay				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50151912 (3-(1-Pyridin-2-yl-1H-pyrazol-4-yl)-benzonitrile \| ...) Show SMILES N#Cc1cccc(c1)-c1cnn(c1)-c1ccccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration towards human glutamate receptor 5 in calcium flux assay				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50151903 (3-(4-Pyridin-2-yl-[1,2,3]triazol-1-yl)-benzonitril...) Show SMILES N#Cc1cccc(c1)-n1cc(nn1)-c1ccccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration towards human glutamate receptor 5 in calcium flux assay				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50151900 (3-(4-Pyridin-2-yl-imidazol-1-yl)-benzonitrile \| CH...) Show SMILES N#Cc1cccc(c1)-n1cnc(c1)-c1ccccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration towards human glutamate receptor 5 in calcium flux assay				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50151902 (3-(1-Pyridin-2-yl-1H-pyrazol-3-yl)-benzonitrile \| ...) Show SMILES N#Cc1cccc(c1)-c1ccn(n1)-c1ccccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration towards human glutamate receptor 5 in calcium flux assay				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50151899 (3-(1-Pyridin-2-yl-1H-pyrrol-3-yl)-benzonitrile \| C...) Show SMILES N#Cc1cccc(c1)-c1ccn(c1)-c1ccccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration towards human glutamate receptor 5 in calcium flux assay				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50151896 (3-(1-Pyridin-2-yl-1H-[1,2,4]triazol-3-yl)-benzonit...) Show SMILES N#Cc1cccc(c1)-c1ncn(n1)-c1ccccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration towards human glutamate receptor 5 in calcium flux assay				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50151908 (3-(1-Pyridin-2-yl-1H-imidazol-4-yl)-benzonitrile \|...) Show SMILES N#Cc1cccc(c1)-c1cn(cn1)-c1ccccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration towards human glutamate receptor 5 in calcium flux assay				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50151911 (3-(1-Pyridin-2-yl-1H-[1,2,3]triazol-4-yl)-benzonit...) Show SMILES N#Cc1cccc(c1)-c1cn(nn1)-c1ccccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration towards human glutamate receptor 5 in calcium flux assay				J Med Chem 47: 4645-8 (2004) Article DOI: 10.1021/jm049828c BindingDB Entry DOI: 10.7270/Q2DJ5F3G
TBA Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%