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PubMed code 15341948

Compile data set for download or QSAR
Found 25 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sphingosine 1-Phosphate Receptor 4


(Homo sapiens (Human))
BDBM50152539
PNG
(CHEMBL183894 | Phosphoric acid mono-[(1R,2R)-2-ami...)
Show SMILES CCCCCCCCc1ccc2nc([nH]c2c1)[C@@H](N)[C@@H](C)OP(O)(O)=O
Show InChI InChI=1S/C18H30N3O4P/c1-3-4-5-6-7-8-9-14-10-11-15-16(12-14)21-18(20-15)17(19)13(2)25-26(22,23)24/h10-13,17H,3-9,19H2,1-2H3,(H,20,21)(H2,22,23,24)/t13-,17+/m1/s1
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n/an/an/an/a 94n/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human Sphingosine 1-phosphate receptor 4 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...


Bioorg Med Chem Lett 14: 4903-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.030
BindingDB Entry DOI: 10.7270/Q26T0NCJ
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 5


(Homo sapiens (Human))
BDBM50152538
PNG
(CHEMBL185491 | Phosphoric acid mono-[(R)-2-amino-2...)
Show SMILES CCCCCCCCc1ccc2nc([nH]c2c1)[C@@H](N)COP(O)(O)=O
Show InChI InChI=1S/C17H28N3O4P/c1-2-3-4-5-6-7-8-13-9-10-15-16(11-13)20-17(19-15)14(18)12-24-25(21,22)23/h9-11,14H,2-8,12,18H2,1H3,(H,19,20)(H2,21,22,23)/t14-/m0/s1
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n/an/an/an/a 6.60n/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human Sphingosine 1-phosphate receptor 5 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...


Bioorg Med Chem Lett 14: 4903-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.030
BindingDB Entry DOI: 10.7270/Q26T0NCJ
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50152541
PNG
((R)-2-Amino-2-(6-octyl-1H-benzoimidazol-2-yl)-etha...)
Show SMILES CCCCCCCCc1ccc2nc([nH]c2c1)[C@@H](N)CO
Show InChI InChI=1S/C17H27N3O/c1-2-3-4-5-6-7-8-13-9-10-15-16(11-13)20-17(19-15)14(18)12-21/h9-11,14,21H,2-8,12,18H2,1H3,(H,19,20)/t14-/m0/s1
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n/an/an/an/a 2.10E+3n/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human Sphingosine 1-phosphate receptor 1 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...


Bioorg Med Chem Lett 14: 4903-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.030
BindingDB Entry DOI: 10.7270/Q26T0NCJ
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50152540
PNG
(CHEMBL433593 | Phosphoric acid mono-[2-amino-2-(6-...)
Show SMILES CCCCCCCCc1ccc2nc([nH]c2c1)C(C)(N)COP(O)(O)=O
Show InChI InChI=1S/C18H30N3O4P/c1-3-4-5-6-7-8-9-14-10-11-15-16(12-14)21-17(20-15)18(2,19)13-25-26(22,23)24/h10-12H,3-9,13,19H2,1-2H3,(H,20,21)(H2,22,23,24)
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n/an/an/an/a 1.00E+3n/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human Sphingosine 1-phosphate receptor 1 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...


Bioorg Med Chem Lett 14: 4903-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.030
BindingDB Entry DOI: 10.7270/Q26T0NCJ
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 4


(Homo sapiens (Human))
BDBM50152538
PNG
(CHEMBL185491 | Phosphoric acid mono-[(R)-2-amino-2...)
Show SMILES CCCCCCCCc1ccc2nc([nH]c2c1)[C@@H](N)COP(O)(O)=O
Show InChI InChI=1S/C17H28N3O4P/c1-2-3-4-5-6-7-8-13-9-10-15-16(11-13)20-17(19-15)14(18)12-24-25(21,22)23/h9-11,14H,2-8,12,18H2,1H3,(H,19,20)(H2,21,22,23)/t14-/m0/s1
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n/an/an/an/a 48n/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human Sphingosine 1-phosphate receptor 4 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...


Bioorg Med Chem Lett 14: 4903-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.030
BindingDB Entry DOI: 10.7270/Q26T0NCJ
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 5


(Homo sapiens (Human))
BDBM50152541
PNG
((R)-2-Amino-2-(6-octyl-1H-benzoimidazol-2-yl)-etha...)
Show SMILES CCCCCCCCc1ccc2nc([nH]c2c1)[C@@H](N)CO
Show InChI InChI=1S/C17H27N3O/c1-2-3-4-5-6-7-8-13-9-10-15-16(11-13)20-17(19-15)14(18)12-21/h9-11,14,21H,2-8,12,18H2,1H3,(H,19,20)/t14-/m0/s1
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n/an/an/an/a 2.40E+3n/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human Sphingosine 1-phosphate receptor 5 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...


Bioorg Med Chem Lett 14: 4903-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.030
BindingDB Entry DOI: 10.7270/Q26T0NCJ
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 4


(Homo sapiens (Human))
BDBM50152542
PNG
((1R,2R)-1-Amino-1-(6-octyl-1H-benzoimidazol-2-yl)-...)
Show SMILES CCCCCCCCc1ccc2nc([nH]c2c1)[C@@H](N)[C@@H](C)O
Show InChI InChI=1S/C18H29N3O/c1-3-4-5-6-7-8-9-14-10-11-15-16(12-14)21-18(20-15)17(19)13(2)22/h10-13,17,22H,3-9,19H2,1-2H3,(H,20,21)/t13-,17+/m1/s1
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n/an/an/an/a 3.30E+4n/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human Sphingosine 1-phosphate receptor 4 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...


Bioorg Med Chem Lett 14: 4903-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.030
BindingDB Entry DOI: 10.7270/Q26T0NCJ
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50152542
PNG
((1R,2R)-1-Amino-1-(6-octyl-1H-benzoimidazol-2-yl)-...)
Show SMILES CCCCCCCCc1ccc2nc([nH]c2c1)[C@@H](N)[C@@H](C)O
Show InChI InChI=1S/C18H29N3O/c1-3-4-5-6-7-8-9-14-10-11-15-16(12-14)21-18(20-15)17(19)13(2)22/h10-13,17,22H,3-9,19H2,1-2H3,(H,20,21)/t13-,17+/m1/s1
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n/an/an/an/a 2.90E+3n/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human Sphingosine 1-phosphate receptor 1 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...


Bioorg Med Chem Lett 14: 4903-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.030
BindingDB Entry DOI: 10.7270/Q26T0NCJ
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 4


(Homo sapiens (Human))
BDBM50152536
PNG
((S)-2-Amino-2-(6-octyl-1H-benzoimidazol-2-yl)-etha...)
Show SMILES CCCCCCCCc1ccc2nc([nH]c2c1)[C@H](N)CO
Show InChI InChI=1S/C17H27N3O/c1-2-3-4-5-6-7-8-13-9-10-15-16(11-13)20-17(19-15)14(18)12-21/h9-11,14,21H,2-8,12,18H2,1H3,(H,19,20)/t14-/m1/s1
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n/an/an/an/a 1.60E+3n/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human Sphingosine 1-phosphate receptor 4 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...


Bioorg Med Chem Lett 14: 4903-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.030
BindingDB Entry DOI: 10.7270/Q26T0NCJ
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50152539
PNG
(CHEMBL183894 | Phosphoric acid mono-[(1R,2R)-2-ami...)
Show SMILES CCCCCCCCc1ccc2nc([nH]c2c1)[C@@H](N)[C@@H](C)OP(O)(O)=O
Show InChI InChI=1S/C18H30N3O4P/c1-3-4-5-6-7-8-9-14-10-11-15-16(12-14)21-18(20-15)17(19)13(2)25-26(22,23)24/h10-13,17H,3-9,19H2,1-2H3,(H,20,21)(H2,22,23,24)/t13-,17+/m1/s1
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n/an/an/an/a 240n/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human Sphingosine 1-phosphate receptor 1 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...


Bioorg Med Chem Lett 14: 4903-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.030
BindingDB Entry DOI: 10.7270/Q26T0NCJ
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 5


(Homo sapiens (Human))
BDBM50158348
PNG
((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Show SMILES CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](N)COP(O)(O)=O |r|
Show InChI InChI=1S/C18H38NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24-25(21,22)23/h14-15,17-18,20H,2-13,16,19H2,1H3,(H2,21,22,23)/b15-14+/t17-,18+/m0/s1
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n/an/an/an/a 1.70n/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human Sphingosine 1-phosphate receptor 5 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...


Bioorg Med Chem Lett 14: 4903-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.030
BindingDB Entry DOI: 10.7270/Q26T0NCJ
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 5


(Homo sapiens (Human))
BDBM50152536
PNG
((S)-2-Amino-2-(6-octyl-1H-benzoimidazol-2-yl)-etha...)
Show SMILES CCCCCCCCc1ccc2nc([nH]c2c1)[C@H](N)CO
Show InChI InChI=1S/C17H27N3O/c1-2-3-4-5-6-7-8-13-9-10-15-16(11-13)20-17(19-15)14(18)12-21/h9-11,14,21H,2-8,12,18H2,1H3,(H,19,20)/t14-/m1/s1
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n/an/an/an/a 390n/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human Sphingosine 1-phosphate receptor 5 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...


Bioorg Med Chem Lett 14: 4903-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.030
BindingDB Entry DOI: 10.7270/Q26T0NCJ
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50152537
PNG
(CHEMBL361915 | Phosphoric acid mono-[(S)-2-amino-2...)
Show SMILES CCCCCCCCc1ccc2nc([nH]c2c1)[C@H](N)COP(O)(O)=O
Show InChI InChI=1S/C17H28N3O4P/c1-2-3-4-5-6-7-8-13-9-10-15-16(11-13)20-17(19-15)14(18)12-24-25(21,22)23/h9-11,14H,2-8,12,18H2,1H3,(H,19,20)(H2,21,22,23)/t14-/m1/s1
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n/an/an/an/a 21n/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human Sphingosine 1-phosphate receptor 1 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...


Bioorg Med Chem Lett 14: 4903-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.030
BindingDB Entry DOI: 10.7270/Q26T0NCJ
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 5


(Homo sapiens (Human))
BDBM50152540
PNG
(CHEMBL433593 | Phosphoric acid mono-[2-amino-2-(6-...)
Show SMILES CCCCCCCCc1ccc2nc([nH]c2c1)C(C)(N)COP(O)(O)=O
Show InChI InChI=1S/C18H30N3O4P/c1-3-4-5-6-7-8-9-14-10-11-15-16(12-14)21-17(20-15)18(2,19)13-25-26(22,23)24/h10-12H,3-9,13,19H2,1-2H3,(H,20,21)(H2,22,23,24)
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n/an/an/an/a 370n/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human Sphingosine 1-phosphate receptor 5 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...


Bioorg Med Chem Lett 14: 4903-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.030
BindingDB Entry DOI: 10.7270/Q26T0NCJ
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 4


(Homo sapiens (Human))
BDBM50152540
PNG
(CHEMBL433593 | Phosphoric acid mono-[2-amino-2-(6-...)
Show SMILES CCCCCCCCc1ccc2nc([nH]c2c1)C(C)(N)COP(O)(O)=O
Show InChI InChI=1S/C18H30N3O4P/c1-3-4-5-6-7-8-9-14-10-11-15-16(12-14)21-17(20-15)18(2,19)13-25-26(22,23)24/h10-12H,3-9,13,19H2,1-2H3,(H,20,21)(H2,22,23,24)
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n/an/an/an/a 1.20E+3n/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human Sphingosine 1-phosphate receptor 4 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...


Bioorg Med Chem Lett 14: 4903-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.030
BindingDB Entry DOI: 10.7270/Q26T0NCJ
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50158348
PNG
((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Show SMILES CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](N)COP(O)(O)=O |r|
Show InChI InChI=1S/C18H38NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24-25(21,22)23/h14-15,17-18,20H,2-13,16,19H2,1H3,(H2,21,22,23)/b15-14+/t17-,18+/m0/s1
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n/an/an/an/a 20n/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human Sphingosine 1-phosphate receptor 1 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...


Bioorg Med Chem Lett 14: 4903-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.030
BindingDB Entry DOI: 10.7270/Q26T0NCJ
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 2


(Homo sapiens (Human))
BDBM50158348
PNG
((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Show SMILES CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](N)COP(O)(O)=O |r|
Show InChI InChI=1S/C18H38NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24-25(21,22)23/h14-15,17-18,20H,2-13,16,19H2,1H3,(H2,21,22,23)/b15-14+/t17-,18+/m0/s1
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n/an/an/an/a 2.20n/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human Sphingosine 1-phosphate receptor 2 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...


Bioorg Med Chem Lett 14: 4903-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.030
BindingDB Entry DOI: 10.7270/Q26T0NCJ
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50152538
PNG
(CHEMBL185491 | Phosphoric acid mono-[(R)-2-amino-2...)
Show SMILES CCCCCCCCc1ccc2nc([nH]c2c1)[C@@H](N)COP(O)(O)=O
Show InChI InChI=1S/C17H28N3O4P/c1-2-3-4-5-6-7-8-13-9-10-15-16(11-13)20-17(19-15)14(18)12-24-25(21,22)23/h9-11,14H,2-8,12,18H2,1H3,(H,19,20)(H2,21,22,23)/t14-/m0/s1
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n/an/an/an/a 37n/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human Sphingosine 1-phosphate receptor 1 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...


Bioorg Med Chem Lett 14: 4903-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.030
BindingDB Entry DOI: 10.7270/Q26T0NCJ
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 5


(Homo sapiens (Human))
BDBM50152537
PNG
(CHEMBL361915 | Phosphoric acid mono-[(S)-2-amino-2...)
Show SMILES CCCCCCCCc1ccc2nc([nH]c2c1)[C@H](N)COP(O)(O)=O
Show InChI InChI=1S/C17H28N3O4P/c1-2-3-4-5-6-7-8-13-9-10-15-16(11-13)20-17(19-15)14(18)12-24-25(21,22)23/h9-11,14H,2-8,12,18H2,1H3,(H,19,20)(H2,21,22,23)/t14-/m1/s1
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n/an/an/an/a 8.20n/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human Sphingosine 1-phosphate receptor 5 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...


Bioorg Med Chem Lett 14: 4903-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.030
BindingDB Entry DOI: 10.7270/Q26T0NCJ
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 4


(Homo sapiens (Human))
BDBM50158348
PNG
((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Show SMILES CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](N)COP(O)(O)=O |r|
Show InChI InChI=1S/C18H38NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24-25(21,22)23/h14-15,17-18,20H,2-13,16,19H2,1H3,(H2,21,22,23)/b15-14+/t17-,18+/m0/s1
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n/an/an/an/a 37n/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human Sphingosine 1-phosphate receptor 4 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...


Bioorg Med Chem Lett 14: 4903-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.030
BindingDB Entry DOI: 10.7270/Q26T0NCJ
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 3


(Homo sapiens (Human))
BDBM50158348
PNG
((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Show SMILES CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](N)COP(O)(O)=O |r|
Show InChI InChI=1S/C18H38NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24-25(21,22)23/h14-15,17-18,20H,2-13,16,19H2,1H3,(H2,21,22,23)/b15-14+/t17-,18+/m0/s1
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n/an/an/an/a 1.20n/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human Sphingosine 1-phosphate receptor 3 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...


Bioorg Med Chem Lett 14: 4903-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.030
BindingDB Entry DOI: 10.7270/Q26T0NCJ
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 4


(Homo sapiens (Human))
BDBM50152541
PNG
((R)-2-Amino-2-(6-octyl-1H-benzoimidazol-2-yl)-etha...)
Show SMILES CCCCCCCCc1ccc2nc([nH]c2c1)[C@@H](N)CO
Show InChI InChI=1S/C17H27N3O/c1-2-3-4-5-6-7-8-13-9-10-15-16(11-13)20-17(19-15)14(18)12-21/h9-11,14,21H,2-8,12,18H2,1H3,(H,19,20)/t14-/m0/s1
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n/an/an/an/a 4.20E+3n/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human Sphingosine 1-phosphate receptor 4 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...


Bioorg Med Chem Lett 14: 4903-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.030
BindingDB Entry DOI: 10.7270/Q26T0NCJ
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 4


(Homo sapiens (Human))
BDBM50152537
PNG
(CHEMBL361915 | Phosphoric acid mono-[(S)-2-amino-2...)
Show SMILES CCCCCCCCc1ccc2nc([nH]c2c1)[C@H](N)COP(O)(O)=O
Show InChI InChI=1S/C17H28N3O4P/c1-2-3-4-5-6-7-8-13-9-10-15-16(11-13)20-17(19-15)14(18)12-24-25(21,22)23/h9-11,14H,2-8,12,18H2,1H3,(H,19,20)(H2,21,22,23)/t14-/m1/s1
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n/an/an/an/a 36n/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human Sphingosine 1-phosphate receptor 4 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...


Bioorg Med Chem Lett 14: 4903-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.030
BindingDB Entry DOI: 10.7270/Q26T0NCJ
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50152536
PNG
((S)-2-Amino-2-(6-octyl-1H-benzoimidazol-2-yl)-etha...)
Show SMILES CCCCCCCCc1ccc2nc([nH]c2c1)[C@H](N)CO
Show InChI InChI=1S/C17H27N3O/c1-2-3-4-5-6-7-8-13-9-10-15-16(11-13)20-17(19-15)14(18)12-21/h9-11,14,21H,2-8,12,18H2,1H3,(H,19,20)/t14-/m1/s1
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n/an/an/an/a 330n/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human Sphingosine 1-phosphate receptor 1 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...


Bioorg Med Chem Lett 14: 4903-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.030
BindingDB Entry DOI: 10.7270/Q26T0NCJ
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 5


(Homo sapiens (Human))
BDBM50152539
PNG
(CHEMBL183894 | Phosphoric acid mono-[(1R,2R)-2-ami...)
Show SMILES CCCCCCCCc1ccc2nc([nH]c2c1)[C@@H](N)[C@@H](C)OP(O)(O)=O
Show InChI InChI=1S/C18H30N3O4P/c1-3-4-5-6-7-8-9-14-10-11-15-16(12-14)21-18(20-15)17(19)13(2)25-26(22,23)24/h10-13,17H,3-9,19H2,1-2H3,(H,20,21)(H2,22,23,24)/t13-,17+/m1/s1
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n/an/an/an/a 77n/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human Sphingosine 1-phosphate receptor 5 expressed in HEK293T cells was determined using [gamma-35S]-GTP as radioli...


Bioorg Med Chem Lett 14: 4903-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.030
BindingDB Entry DOI: 10.7270/Q26T0NCJ
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%