Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50005120 (CHEMBL274491 | N-((2S,3S)-1-Benzyl-2-methyl-pyrrol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity towards DA D-2 receptor using radioligand [3H]SPI | J Med Chem 35: 2355-63 (1992) BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50132693 (4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-met...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity towards DA D-2 receptor using radioligand [3H]SPI | J Med Chem 35: 2355-63 (1992) BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50005118 ((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 9.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity towards DA D-2 receptor using radioligand [3H]SPI | J Med Chem 35: 2355-63 (1992) BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50005117 ((racemic)5'-(5-Ethanesulfonyl-2-methoxy-phenyl)-1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents | PubMed | 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity towards Dopamine receptor D2 using radioligand [3H]SPI | J Med Chem 35: 2355-63 (1992) BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM81774 (CAS_15676-16-1 | SULPIRIDE,(+) | Sulpiride-S | Sul...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | PubMed | 39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Inhibitory concentration required for displacing radioligand [3H]SPI from DA D-2 receptor | J Med Chem 35: 2355-63 (1992) BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM48320 (4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | PubMed | 104 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity towards DA D-2 receptor using radioligand [3H]SPI | J Med Chem 35: 2355-63 (1992) BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM48320 (4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | PubMed | 104 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Inhibitory concentration required for displacing radioligand [3H]SPI from DA D-2 receptor | J Med Chem 35: 2355-63 (1992) BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50005120 (CHEMBL274491 | N-((2S,3S)-1-Benzyl-2-methyl-pyrrol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.490 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Inhibitory concentration required for displacing radioligand [3H]SPI from DA D-2 receptor | J Med Chem 35: 2355-63 (1992) BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50132693 (4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-met...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Inhibitory concentration required for displacing radioligand [3H]SPI from DA D-2 receptor | J Med Chem 35: 2355-63 (1992) BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50005118 ((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity towards DA D-2 receptor using radioligand [3H]SPI | J Med Chem 35: 2355-63 (1992) BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM81774 (CAS_15676-16-1 | SULPIRIDE,(+) | Sulpiride-S | Sul...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Inhibitory concentration required for displacing radioligand [3H]SPI from DA D-2 receptor | J Med Chem 35: 2355-63 (1992) BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM81774 (CAS_15676-16-1 | SULPIRIDE,(+) | Sulpiride-S | Sul...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 233 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity towards DA D-2 receptor using radioligand [3H]SPI | J Med Chem 35: 2355-63 (1992) BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM48320 (4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 820 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Inhibitory concentration required for displacing radioligand [3H]SPI from DA D-2 receptor | J Med Chem 35: 2355-63 (1992) BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50005121 ((R)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Inhibitory concentration required for displacing radioligand [3H]SPI from Dopamine receptor D2 | J Med Chem 35: 2355-63 (1992) BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair |