Found 228 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Collagenase 3
(Homo sapiens (Human)) | BDBM50152914
(1-Ethynyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-ben...)Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2CN(CCC2C(=O)NO)C#C)c2ccccc2n1 Show InChI InChI=1S/C26H27N3O5S/c1-3-29-13-12-24(26(30)28-31)20(15-29)17-35(32,33)22-10-8-21(9-11-22)34-16-19-14-18(2)27-25-7-5-4-6-23(19)25/h1,4-11,14,20,24,31H,12-13,15-17H2,2H3,(H,28,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 377 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-13 (MMP-13) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50152909
(1-Allyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-benze...)Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2CN(CC=C)CCC2C(=O)NO)c2ccccc2n1 Show InChI InChI=1S/C27H31N3O5S/c1-3-13-30-14-12-25(27(31)29-32)21(16-30)18-36(33,34)23-10-8-22(9-11-23)35-17-20-15-19(2)28-26-7-5-4-6-24(20)26/h3-11,15,21,25,32H,1,12-14,16-18H2,2H3,(H,29,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 503 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-13 (MMP-13) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50152930
(CHEMBL359569 | N-Hydroxy-2-{1-isobutyl-3-[4-(2-met...)Show SMILES CC(C)CN1CCC(CC(=O)NO)(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1 Show InChI InChI=1S/C28H35N3O5S/c1-20(2)16-31-13-12-28(18-31,15-27(32)30-33)19-37(34,35)24-10-8-23(9-11-24)36-17-22-14-21(3)29-26-7-5-4-6-25(22)26/h4-11,14,20,33H,12-13,15-19H2,1-3H3,(H,30,32) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 603 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-13 (MMP-13) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50152924
(CHEMBL184553 | N-Hydroxy-2-{1-isopropyl-3-[4-(2-me...)Show SMILES CC(C)N1CCC(CC(=O)NO)(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1 Show InChI InChI=1S/C27H33N3O5S/c1-19(2)30-13-12-27(17-30,15-26(31)29-32)18-36(33,34)23-10-8-22(9-11-23)35-16-21-14-20(3)28-25-7-5-4-6-24(21)25/h4-11,14,19,32H,12-13,15-18H2,1-3H3,(H,29,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 653 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-13 (MMP-13) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50152915
(CHEMBL185321 | N-Hydroxy-2-{2-[4-(2-methyl-quinoli...)Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2(CC(=O)NO)CCCCN2)c2ccccc2n1 Show InChI InChI=1S/C25H29N3O5S/c1-18-14-19(22-6-2-3-7-23(22)27-18)16-33-20-8-10-21(11-9-20)34(31,32)17-25(15-24(29)28-30)12-4-5-13-26-25/h2-3,6-11,14,26,30H,4-5,12-13,15-17H2,1H3,(H,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 753 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-13 (MMP-13) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50152933
(CHEMBL364875 | N-Hydroxy-2-{1-[4-(2-methyl-quinoli...)Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2(CC(=O)NO)CCC2)c2ccccc2n1 Show InChI InChI=1S/C24H26N2O5S/c1-17-13-18(21-5-2-3-6-22(21)25-17)15-31-19-7-9-20(10-8-19)32(29,30)16-24(11-4-12-24)14-23(27)26-28/h2-3,5-10,13,28H,4,11-12,14-16H2,1H3,(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 753 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-13 (MMP-13) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50152907
(2-[4-(2-Methyl-quinolin-4-ylmethoxy)-benzenesulfon...)Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2NCCCC2C(=O)NO)c2ccccc2n1 Show InChI InChI=1S/C24H27N3O5S/c1-16-13-17(20-5-2-3-7-22(20)26-16)14-32-18-8-10-19(11-9-18)33(30,31)15-23-21(24(28)27-29)6-4-12-25-23/h2-3,5,7-11,13,21,23,25,29H,4,6,12,14-15H2,1H3,(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 754 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-13 (MMP-13) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50152922
(CHEMBL184302 | N-Hydroxy-2-{1-[4-(2-methyl-quinoli...)Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2(CC(=O)NO)CCCC2)c2ccccc2n1 Show InChI InChI=1S/C25H28N2O5S/c1-18-14-19(22-6-2-3-7-23(22)26-18)16-32-20-8-10-21(11-9-20)33(30,31)17-25(12-4-5-13-25)15-24(28)27-29/h2-3,6-11,14,29H,4-5,12-13,15-17H2,1H3,(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 804 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-13 (MMP-13) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50152926
(2-[4-(2-Methyl-quinolin-4-ylmethoxy)-benzenesulfon...)Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2NCCC2C(=O)NO)c2ccccc2n1 Show InChI InChI=1S/C23H25N3O5S/c1-15-12-16(19-4-2-3-5-21(19)25-15)13-31-17-6-8-18(9-7-17)32(29,30)14-22-20(10-11-24-22)23(27)26-28/h2-9,12,20,22,24,28H,10-11,13-14H2,1H3,(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 955 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-13 (MMP-13) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50152928
(CHEMBL365905 | N-Hydroxy-2-{1-[4-(2-methyl-quinoli...)Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2(CC(=O)NO)CCCCC2)c2ccccc2n1 Show InChI InChI=1S/C26H30N2O5S/c1-19-15-20(23-7-3-4-8-24(23)27-19)17-33-21-9-11-22(12-10-21)34(31,32)18-26(16-25(29)28-30)13-5-2-6-14-26/h3-4,7-12,15,30H,2,5-6,13-14,16-18H2,1H3,(H,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-13 (MMP-13) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50152903
(CHEMBL184889 | N-Hydroxy-2-{1-isobutyl-2-[4-(2-met...)Show SMILES CC(C)CN1CCCC1(CC(=O)NO)CS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 Show InChI InChI=1S/C28H35N3O5S/c1-20(2)17-31-14-6-13-28(31,16-27(32)30-33)19-37(34,35)24-11-9-23(10-12-24)36-18-22-15-21(3)29-26-8-5-4-7-25(22)26/h4-5,7-12,15,20,33H,6,13-14,16-19H2,1-3H3,(H,30,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
inhibition of Matrix metalloprotease-2 (MMP-2) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50152924
(CHEMBL184553 | N-Hydroxy-2-{1-isopropyl-3-[4-(2-me...)Show SMILES CC(C)N1CCC(CC(=O)NO)(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1 Show InChI InChI=1S/C27H33N3O5S/c1-19(2)30-13-12-27(17-30,15-26(31)29-32)18-36(33,34)23-10-8-22(9-11-23)35-16-21-14-20(3)28-25-7-5-4-6-24(21)25/h4-11,14,19,32H,12-13,15-18H2,1-3H3,(H,29,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
inhibition of Matrix metalloprotease-2 (MMP-2) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50152928
(CHEMBL365905 | N-Hydroxy-2-{1-[4-(2-methyl-quinoli...)Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2(CC(=O)NO)CCCCC2)c2ccccc2n1 Show InChI InChI=1S/C26H30N2O5S/c1-19-15-20(23-7-3-4-8-24(23)27-19)17-33-21-9-11-22(12-10-21)34(31,32)18-26(16-25(29)28-30)13-5-2-6-14-26/h3-4,7-12,15,30H,2,5-6,13-14,16-18H2,1H3,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
inhibition of Matrix metalloprotease-2 (MMP-2) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152922
(CHEMBL184302 | N-Hydroxy-2-{1-[4-(2-methyl-quinoli...)Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2(CC(=O)NO)CCCC2)c2ccccc2n1 Show InChI InChI=1S/C25H28N2O5S/c1-18-14-19(22-6-2-3-7-23(22)26-18)16-32-20-8-10-21(11-9-20)33(30,31)17-25(12-4-5-13-25)15-24(28)27-29/h2-3,6-11,14,29H,4-5,12-13,15-17H2,1H3,(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50152922
(CHEMBL184302 | N-Hydroxy-2-{1-[4-(2-methyl-quinoli...)Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2(CC(=O)NO)CCCC2)c2ccccc2n1 Show InChI InChI=1S/C25H28N2O5S/c1-18-14-19(22-6-2-3-7-23(22)26-18)16-32-20-8-10-21(11-9-20)33(30,31)17-25(12-4-5-13-25)15-24(28)27-29/h2-3,6-11,14,29H,4-5,12-13,15-17H2,1H3,(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
inhibition of Matrix metalloprotease-2 (MMP-2) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50152901
(1-Methyl-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benz...)Show SMILES CN1CCC(C1CS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO Show InChI InChI=1S/C24H27N3O5S/c1-16-13-17(20-5-3-4-6-22(20)25-16)14-32-18-7-9-19(10-8-18)33(30,31)15-23-21(24(28)26-29)11-12-27(23)2/h3-10,13,21,23,29H,11-12,14-15H2,1-2H3,(H,26,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.71E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-13 (MMP-13) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50152936
(CHEMBL363732 | N-Hydroxy-2-{3-[4-(2-methyl-quinoli...)Show SMILES CCCCCN1CCC(CC(=O)NO)(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1 Show InChI InChI=1S/C29H37N3O5S/c1-3-4-7-15-32-16-14-29(20-32,18-28(33)31-34)21-38(35,36)25-12-10-24(11-13-25)37-19-23-17-22(2)30-27-9-6-5-8-26(23)27/h5-6,8-13,17,34H,3-4,7,14-16,18-21H2,1-2H3,(H,31,33) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-13 (MMP-13) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152905
(CHEMBL184782 | N-Hydroxy-2-{3-[4-(2-methyl-quinoli...)Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2(CC(=O)NO)CCNC2)c2ccccc2n1 Show InChI InChI=1S/C24H27N3O5S/c1-17-12-18(21-4-2-3-5-22(21)26-17)14-32-19-6-8-20(9-7-19)33(30,31)16-24(10-11-25-15-24)13-23(28)27-29/h2-9,12,25,29H,10-11,13-16H2,1H3,(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152930
(CHEMBL359569 | N-Hydroxy-2-{1-isobutyl-3-[4-(2-met...)Show SMILES CC(C)CN1CCC(CC(=O)NO)(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1 Show InChI InChI=1S/C28H35N3O5S/c1-20(2)16-31-13-12-28(18-31,15-27(32)30-33)19-37(34,35)24-10-8-23(9-11-24)36-17-22-14-21(3)29-26-7-5-4-6-25(22)26/h4-11,14,20,33H,12-13,15-19H2,1-3H3,(H,30,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152904
(CHEMBL184975 | N-Hydroxy-2-{3-[4-(2-methyl-quinoli...)Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2(CC(=O)NO)CCCNC2)c2ccccc2n1 Show InChI InChI=1S/C25H29N3O5S/c1-18-13-19(22-5-2-3-6-23(22)27-18)15-33-20-7-9-21(10-8-20)34(31,32)17-25(14-24(29)28-30)11-4-12-26-16-25/h2-3,5-10,13,26,30H,4,11-12,14-17H2,1H3,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152937
(1-Isopropyl-4-[4-(2-methyl-quinolin-4-ylmethoxy)-b...)Show SMILES CC(C)N1CCC(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C(C1)C(=O)NO Show InChI InChI=1S/C27H33N3O5S/c1-18(2)30-13-12-20(25(15-30)27(31)29-32)17-36(33,34)23-10-8-22(9-11-23)35-16-21-14-19(3)28-26-7-5-4-6-24(21)26/h4-11,14,18,20,25,32H,12-13,15-17H2,1-3H3,(H,29,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152931
(CHEMBL185587 | N-Hydroxy-2-{1-methyl-4-[4-(2-methy...)Show SMILES CN1CCC(CC(=O)NO)(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)CC1 Show InChI InChI=1S/C26H31N3O5S/c1-19-15-20(23-5-3-4-6-24(23)27-19)17-34-21-7-9-22(10-8-21)35(32,33)18-26(16-25(30)28-31)11-13-29(2)14-12-26/h3-10,15,31H,11-14,16-18H2,1-2H3,(H,28,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152909
(1-Allyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-benze...)Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2CN(CC=C)CCC2C(=O)NO)c2ccccc2n1 Show InChI InChI=1S/C27H31N3O5S/c1-3-13-30-14-12-25(27(31)29-32)21(16-30)18-36(33,34)23-10-8-22(9-11-23)35-17-20-15-19(2)28-26-7-5-4-6-24(20)26/h3-11,15,21,25,32H,1,12-14,16-18H2,2H3,(H,29,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152915
(CHEMBL185321 | N-Hydroxy-2-{2-[4-(2-methyl-quinoli...)Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2(CC(=O)NO)CCCCN2)c2ccccc2n1 Show InChI InChI=1S/C25H29N3O5S/c1-18-14-19(22-6-2-3-7-23(22)27-18)16-33-20-8-10-21(11-9-20)34(31,32)17-25(15-24(29)28-30)12-4-5-13-26-25/h2-3,6-11,14,26,30H,4-5,12-13,15-17H2,1H3,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152933
(CHEMBL364875 | N-Hydroxy-2-{1-[4-(2-methyl-quinoli...)Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2(CC(=O)NO)CCC2)c2ccccc2n1 Show InChI InChI=1S/C24H26N2O5S/c1-17-13-18(21-5-2-3-6-22(21)25-17)15-31-19-7-9-20(10-8-19)32(29,30)16-24(11-4-12-24)14-23(27)26-28/h2-3,5-10,13,28H,4,11-12,14-16H2,1H3,(H,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152907
(2-[4-(2-Methyl-quinolin-4-ylmethoxy)-benzenesulfon...)Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2NCCCC2C(=O)NO)c2ccccc2n1 Show InChI InChI=1S/C24H27N3O5S/c1-16-13-17(20-5-2-3-7-22(20)26-16)14-32-18-8-10-19(11-9-18)33(30,31)15-23-21(24(28)27-29)6-4-12-25-23/h2-3,5,7-11,13,21,23,25,29H,4,6,12,14-15H2,1H3,(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152926
(2-[4-(2-Methyl-quinolin-4-ylmethoxy)-benzenesulfon...)Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2NCCC2C(=O)NO)c2ccccc2n1 Show InChI InChI=1S/C23H25N3O5S/c1-15-12-16(19-4-2-3-5-21(19)25-15)13-31-17-6-8-18(9-7-17)32(29,30)14-22-20(10-11-24-22)23(27)26-28/h2-9,12,20,22,24,28H,10-11,13-14H2,1H3,(H,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152910
(1-Butyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-benze...)Show SMILES CCCCN1CCC(C(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1)C(=O)NO Show InChI InChI=1S/C28H35N3O5S/c1-3-4-14-31-15-13-26(28(32)30-33)22(17-31)19-37(34,35)24-11-9-23(10-12-24)36-18-21-16-20(2)29-27-8-6-5-7-25(21)27/h5-12,16,22,26,33H,3-4,13-15,17-19H2,1-2H3,(H,30,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152917
(CHEMBL361376 | N-Hydroxy-2-{3-[4-(2-methyl-quinoli...)Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2(CC(=O)NO)COC2)c2ccccc2n1 Show InChI InChI=1S/C23H24N2O6S/c1-16-10-17(20-4-2-3-5-21(20)24-16)12-31-18-6-8-19(9-7-18)32(28,29)15-23(13-30-14-23)11-22(26)25-27/h2-10,27H,11-15H2,1H3,(H,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152901
(1-Methyl-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benz...)Show SMILES CN1CCC(C1CS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO Show InChI InChI=1S/C24H27N3O5S/c1-16-13-17(20-5-3-4-6-22(20)25-16)14-32-18-7-9-19(10-8-18)33(30,31)15-23-21(24(28)26-29)11-12-27(23)2/h3-10,13,21,23,29H,11-12,14-15H2,1-2H3,(H,26,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152936
(CHEMBL363732 | N-Hydroxy-2-{3-[4-(2-methyl-quinoli...)Show SMILES CCCCCN1CCC(CC(=O)NO)(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1 Show InChI InChI=1S/C29H37N3O5S/c1-3-4-7-15-32-16-14-29(20-32,18-28(33)31-34)21-38(35,36)25-12-10-24(11-13-25)37-19-23-17-22(2)30-27-9-6-5-8-26(23)27/h5-6,8-13,17,34H,3-4,7,14-16,18-21H2,1-2H3,(H,31,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152911
(1-Methyl-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benz...)Show SMILES CN1CCCC(C1CS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO Show InChI InChI=1S/C25H29N3O5S/c1-17-14-18(21-6-3-4-8-23(21)26-17)15-33-19-9-11-20(12-10-19)34(31,32)16-24-22(25(29)27-30)7-5-13-28(24)2/h3-4,6,8-12,14,22,24,30H,5,7,13,15-16H2,1-2H3,(H,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152929
(CHEMBL434348 | N-Hydroxy-2-{1-methyl-3-[4-(2-methy...)Show SMILES CN1CCC(CC(=O)NO)(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1 Show InChI InChI=1S/C25H29N3O5S/c1-18-13-19(22-5-3-4-6-23(22)26-18)15-33-20-7-9-21(10-8-20)34(31,32)17-25(14-24(29)27-30)11-12-28(2)16-25/h3-10,13,30H,11-12,14-17H2,1-2H3,(H,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152924
(CHEMBL184553 | N-Hydroxy-2-{1-isopropyl-3-[4-(2-me...)Show SMILES CC(C)N1CCC(CC(=O)NO)(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1 Show InChI InChI=1S/C27H33N3O5S/c1-19(2)30-13-12-27(17-30,15-26(31)29-32)18-36(33,34)23-10-8-22(9-11-23)35-16-21-14-20(3)28-25-7-5-4-6-24(21)25/h4-11,14,19,32H,12-13,15-18H2,1-3H3,(H,29,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152921
(2-{1-Acetyl-2-[4-(2-methyl-quinolin-4-ylmethoxy)-b...)Show SMILES CC(=O)N1CCCC1(CC(=O)NO)CS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 Show InChI InChI=1S/C26H29N3O6S/c1-18-14-20(23-6-3-4-7-24(23)27-18)16-35-21-8-10-22(11-9-21)36(33,34)17-26(15-25(31)28-32)12-5-13-29(26)19(2)30/h3-4,6-11,14,32H,5,12-13,15-17H2,1-2H3,(H,28,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152923
(CHEMBL183828 | N-Hydroxy-2-{1-isobutyl-3-[4-(2-met...)Show SMILES CC(C)CN1CCCC(CC(=O)NO)(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1 Show InChI InChI=1S/C29H37N3O5S/c1-21(2)17-32-14-6-13-29(19-32,16-28(33)31-34)20-38(35,36)25-11-9-24(10-12-25)37-18-23-15-22(3)30-27-8-5-4-7-26(23)27/h4-5,7-12,15,21,34H,6,13-14,16-20H2,1-3H3,(H,31,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152902
(CHEMBL185397 | N-Hydroxy-2-{4-[4-(2-methyl-quinoli...)Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2(CC(=O)NO)CCOCC2)c2ccccc2n1 Show InChI InChI=1S/C25H28N2O6S/c1-18-14-19(22-4-2-3-5-23(22)26-18)16-33-20-6-8-21(9-7-20)34(30,31)17-25(15-24(28)27-29)10-12-32-13-11-25/h2-9,14,29H,10-13,15-17H2,1H3,(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152899
(CHEMBL365031 | N-Hydroxy-2-{1-methyl-3-[4-(2-methy...)Show SMILES CN1CCCC(CC(=O)NO)(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1 Show InChI InChI=1S/C26H31N3O5S/c1-19-14-20(23-6-3-4-7-24(23)27-19)16-34-21-8-10-22(11-9-21)35(32,33)18-26(15-25(30)28-31)12-5-13-29(2)17-26/h3-4,6-11,14,31H,5,12-13,15-18H2,1-2H3,(H,28,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152900
(1-Isopropyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-b...)Show SMILES CC(C)N1CCC(C(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1)C(=O)NO Show InChI InChI=1S/C27H33N3O5S/c1-18(2)30-13-12-25(27(31)29-32)21(15-30)17-36(33,34)23-10-8-22(9-11-23)35-16-20-14-19(3)28-26-7-5-4-6-24(20)26/h4-11,14,18,21,25,32H,12-13,15-17H2,1-3H3,(H,29,31) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152908
(1-Methyl-4-[4-(2-methyl-quinolin-4-ylmethoxy)-benz...)Show SMILES CN1CCC(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C(C1)C(=O)NO Show InChI InChI=1S/C25H29N3O5S/c1-17-13-19(22-5-3-4-6-24(22)26-17)15-33-20-7-9-21(10-8-20)34(31,32)16-18-11-12-28(2)14-23(18)25(29)27-30/h3-10,13,18,23,30H,11-12,14-16H2,1-2H3,(H,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152918
(CHEMBL184266 | N-Hydroxy-2-{1-isopropyl-3-[4-(2-me...)Show SMILES CC(C)N1CCCC(CC(=O)NO)(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1 Show InChI InChI=1S/C28H35N3O5S/c1-20(2)31-14-6-13-28(18-31,16-27(32)30-33)19-37(34,35)24-11-9-23(10-12-24)36-17-22-15-21(3)29-26-8-5-4-7-25(22)26/h4-5,7-12,15,20,33H,6,13-14,16-19H2,1-3H3,(H,30,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152916
((S)-1-Methyl-piperidine-2,3-dicarboxylic acid 3-(m...)Show SMILES CONC(=O)[C@H]1CCCN(C)[C@@H]1C(=O)Nc1ccc(OCc2cc(C)nc3ccccc23)cc1 Show InChI InChI=1S/C26H30N4O4/c1-17-15-18(21-7-4-5-9-23(21)27-17)16-34-20-12-10-19(11-13-20)28-26(32)24-22(25(31)29-33-3)8-6-14-30(24)2/h4-5,7,9-13,15,22,24H,6,8,14,16H2,1-3H3,(H,28,32)(H,29,31)/t22-,24-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152903
(CHEMBL184889 | N-Hydroxy-2-{1-isobutyl-2-[4-(2-met...)Show SMILES CC(C)CN1CCCC1(CC(=O)NO)CS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 Show InChI InChI=1S/C28H35N3O5S/c1-20(2)17-31-14-6-13-28(31,16-27(32)30-33)19-37(34,35)24-11-9-23(10-12-24)36-18-22-15-21(3)29-26-8-5-4-7-25(22)26/h4-5,7-12,15,20,33H,6,13-14,16-19H2,1-3H3,(H,30,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152928
(CHEMBL365905 | N-Hydroxy-2-{1-[4-(2-methyl-quinoli...)Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2(CC(=O)NO)CCCCC2)c2ccccc2n1 Show InChI InChI=1S/C26H30N2O5S/c1-19-15-20(23-7-3-4-8-24(23)27-19)17-33-21-9-11-22(12-10-21)34(31,32)18-26(16-25(29)28-30)13-5-2-6-14-26/h3-4,7-12,15,30H,2,5-6,13-14,16-18H2,1H3,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152932
(CHEMBL183868 | N-Hydroxy-2-{2-[4-(2-methyl-quinoli...)Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2(CC(=O)NO)CCCO2)c2ccccc2n1 Show InChI InChI=1S/C24H26N2O6S/c1-17-13-18(21-5-2-3-6-22(21)25-17)15-31-19-7-9-20(10-8-19)33(29,30)16-24(11-4-12-32-24)14-23(27)26-28/h2-3,5-10,13,28H,4,11-12,14-16H2,1H3,(H,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152913
(CHEMBL182730 | N-Hydroxy-2-{1-methyl-2-[4-(2-methy...)Show SMILES CN1CCCC1(CC(=O)NO)CS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 Show InChI InChI=1S/C25H29N3O5S/c1-18-14-19(22-6-3-4-7-23(22)26-18)16-33-20-8-10-21(11-9-20)34(31,32)17-25(15-24(29)27-30)12-5-13-28(25)2/h3-4,6-11,14,30H,5,12-13,15-17H2,1-2H3,(H,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152914
(1-Ethynyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-ben...)Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2CN(CCC2C(=O)NO)C#C)c2ccccc2n1 Show InChI InChI=1S/C26H27N3O5S/c1-3-29-13-12-24(26(30)28-31)20(15-29)17-35(32,33)22-10-8-21(9-11-22)34-16-19-14-18(2)27-25-7-5-4-6-23(19)25/h1,4-11,14,20,24,31H,12-13,15-17H2,2H3,(H,28,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152927
(1-Methyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-benz...)Show SMILES CN1CCC(C(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1)C(=O)NO Show InChI InChI=1S/C25H29N3O5S/c1-17-13-18(22-5-3-4-6-24(22)26-17)15-33-20-7-9-21(10-8-20)34(31,32)16-19-14-28(2)12-11-23(19)25(29)27-30/h3-10,13,19,23,30H,11-12,14-16H2,1-2H3,(H,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152920
(3-[4-(2-Methyl-quinolin-4-ylmethoxy)-benzenesulfon...)Show SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2CNCCC2C(=O)NO)c2ccccc2n1 Show InChI InChI=1S/C24H27N3O5S/c1-16-12-17(21-4-2-3-5-23(21)26-16)14-32-19-6-8-20(9-7-19)33(30,31)15-18-13-25-11-10-22(18)24(28)27-29/h2-9,12,18,22,25,29H,10-11,13-15H2,1H3,(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152919
(CHEMBL184200 | N-Hydroxy-2-{1-methyl-2-[4-(2-methy...)Show SMILES CN1CCCCC1(CC(=O)NO)CS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 Show InChI InChI=1S/C26H31N3O5S/c1-19-15-20(23-7-3-4-8-24(23)27-19)17-34-21-9-11-22(12-10-21)35(32,33)18-26(16-25(30)28-31)13-5-6-14-29(26)2/h3-4,7-12,15,31H,5-6,13-14,16-18H2,1-2H3,(H,28,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of Matrix metalloprotease-9 (MMP-9) |
Bioorg Med Chem Lett 14: 4453-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.06.049
BindingDB Entry DOI: 10.7270/Q2NV9HRM |
More data for this
Ligand-Target Pair | |
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