Affinity Data by PubMed id=15454224

PubMed code 15454224

Found 15 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19130 ((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
CREST Research Project Curated by ChEMBL					Assay Description Inhibition of human histone deacetylase 1 prepared from 293T cells				Bioorg Med Chem Lett 14: 5343-6 (2004) Article DOI: 10.1016/j.bmcl.2004.08.016 BindingDB Entry DOI: 10.7270/Q2222VJ6
CREST Research Project Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19130 ((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
CREST Research Project Curated by ChEMBL					Assay Description Inhibition of human histone deacetylase 4 prepared from 293T cells				Bioorg Med Chem Lett 14: 5343-6 (2004) Article DOI: 10.1016/j.bmcl.2004.08.016 BindingDB Entry DOI: 10.7270/Q2222VJ6
CREST Research Project Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM19130 ((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
CREST Research Project Curated by ChEMBL					Assay Description Inhibition of human histone deacetylase 6 prepared from 293T cells				Bioorg Med Chem Lett 14: 5343-6 (2004) Article DOI: 10.1016/j.bmcl.2004.08.016 BindingDB Entry DOI: 10.7270/Q2222VJ6
CREST Research Project Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 8 (Homo sapiens (Human))	BDBM19130 ((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
CREST Research Project Curated by ChEMBL					Assay Description Inhibition of human histone deacetylase 8 prepared from 293T cells				Bioorg Med Chem Lett 14: 5343-6 (2004) Article DOI: 10.1016/j.bmcl.2004.08.016 BindingDB Entry DOI: 10.7270/Q2222VJ6
CREST Research Project Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50153767 ((5S,8R,11S,13aR)-5-sec-Butyl-8-(4-methoxy-benzyl)-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
CREST Research Project Curated by ChEMBL					Assay Description Inhibition of human histone deacetylase 1 prepared from 293T cells				Bioorg Med Chem Lett 14: 5343-6 (2004) Article DOI: 10.1016/j.bmcl.2004.08.016 BindingDB Entry DOI: 10.7270/Q2222VJ6
CREST Research Project Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50153767 ((5S,8R,11S,13aR)-5-sec-Butyl-8-(4-methoxy-benzyl)-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
CREST Research Project Curated by ChEMBL					Assay Description Inhibition of human histone deacetylase 6 prepared from 293T cells				Bioorg Med Chem Lett 14: 5343-6 (2004) Article DOI: 10.1016/j.bmcl.2004.08.016 BindingDB Entry DOI: 10.7270/Q2222VJ6
CREST Research Project Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM50153767 ((5S,8R,11S,13aR)-5-sec-Butyl-8-(4-methoxy-benzyl)-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
CREST Research Project Curated by ChEMBL					Assay Description Inhibition of human histone deacetylase 4 prepared from 293T cells				Bioorg Med Chem Lett 14: 5343-6 (2004) Article DOI: 10.1016/j.bmcl.2004.08.016 BindingDB Entry DOI: 10.7270/Q2222VJ6
CREST Research Project Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50153767 ((5S,8R,11S,13aR)-5-sec-Butyl-8-(4-methoxy-benzyl)-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
CREST Research Project Curated by ChEMBL					Assay Description Inhibition of human histone deacetylase 8 prepared from 293T cells				Bioorg Med Chem Lett 14: 5343-6 (2004) Article DOI: 10.1016/j.bmcl.2004.08.016 BindingDB Entry DOI: 10.7270/Q2222VJ6
CREST Research Project Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50153766 ((5S,8R,11S,13aR)-5-sec-Butyl-8-(4-methoxy-benzyl)-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
CREST Research Project Curated by ChEMBL					Assay Description Inhibition of human histone deacetylase 8 prepared from 293T cells				Bioorg Med Chem Lett 14: 5343-6 (2004) Article DOI: 10.1016/j.bmcl.2004.08.016 BindingDB Entry DOI: 10.7270/Q2222VJ6
CREST Research Project Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM50153766 ((5S,8R,11S,13aR)-5-sec-Butyl-8-(4-methoxy-benzyl)-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
CREST Research Project Curated by ChEMBL					Assay Description Inhibition of human histone deacetylase 4 prepared from 293T cells				Bioorg Med Chem Lett 14: 5343-6 (2004) Article DOI: 10.1016/j.bmcl.2004.08.016 BindingDB Entry DOI: 10.7270/Q2222VJ6
CREST Research Project Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50153766 ((5S,8R,11S,13aR)-5-sec-Butyl-8-(4-methoxy-benzyl)-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
CREST Research Project Curated by ChEMBL					Assay Description Inhibition of human histone deacetylase 1 prepared from 293T cells				Bioorg Med Chem Lett 14: 5343-6 (2004) Article DOI: 10.1016/j.bmcl.2004.08.016 BindingDB Entry DOI: 10.7270/Q2222VJ6
CREST Research Project Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50153765 ((5S,8R,11S,13aR)-5-sec-Butyl-8-(4-methoxy-benzyl)-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
CREST Research Project Curated by ChEMBL					Assay Description Inhibition of human histone deacetylase 8 prepared from 293T cells				Bioorg Med Chem Lett 14: 5343-6 (2004) Article DOI: 10.1016/j.bmcl.2004.08.016 BindingDB Entry DOI: 10.7270/Q2222VJ6
CREST Research Project Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50153765 ((5S,8R,11S,13aR)-5-sec-Butyl-8-(4-methoxy-benzyl)-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
CREST Research Project Curated by ChEMBL					Assay Description Inhibition of human histone deacetylase 1 prepared from 293T cells				Bioorg Med Chem Lett 14: 5343-6 (2004) Article DOI: 10.1016/j.bmcl.2004.08.016 BindingDB Entry DOI: 10.7270/Q2222VJ6
CREST Research Project Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50153766 ((5S,8R,11S,13aR)-5-sec-Butyl-8-(4-methoxy-benzyl)-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
CREST Research Project Curated by ChEMBL					Assay Description Inhibition of human histone deacetylase 6 prepared from 293T cells				Bioorg Med Chem Lett 14: 5343-6 (2004) Article DOI: 10.1016/j.bmcl.2004.08.016 BindingDB Entry DOI: 10.7270/Q2222VJ6
CREST Research Project Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50153765 ((5S,8R,11S,13aR)-5-sec-Butyl-8-(4-methoxy-benzyl)-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
CREST Research Project Curated by ChEMBL					Assay Description Inhibition of human histone deacetylase 6 prepared from 293T cells				Bioorg Med Chem Lett 14: 5343-6 (2004) Article DOI: 10.1016/j.bmcl.2004.08.016 BindingDB Entry DOI: 10.7270/Q2222VJ6
CREST Research Project Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%