Found 24 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50155130
(CHEMBL185958 | Dimethyl-{2-[3-(naphthalene-1-sulfo...)Show SMILES CN(C)CCn1cc(c2ccccc12)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C22H22N2O2S/c1-23(2)14-15-24-16-22(19-11-5-6-12-20(19)24)27(25,26)21-13-7-9-17-8-3-4-10-18(17)21/h3-13,16H,14-15H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells |
Bioorg Med Chem Lett 14: 5499-502 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.003
BindingDB Entry DOI: 10.7270/Q2SB457X |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50155142
(CHEMBL187278 | [2-(1-Benzenesulfonyl-1H-indol-3-yl...)Show InChI InChI=1S/C17H18N2O2S/c1-18-12-11-14-13-19(17-10-6-5-9-16(14)17)22(20,21)15-7-3-2-4-8-15/h2-10,13,18H,11-12H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells |
Bioorg Med Chem Lett 14: 5499-502 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.003
BindingDB Entry DOI: 10.7270/Q2SB457X |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50155135
(CHEMBL184652 | Methyl-{2-[3-(naphthalene-1-sulfony...)Show InChI InChI=1S/C21H20N2O2S/c1-22-13-14-23-15-21(18-10-4-5-11-19(18)23)26(24,25)20-12-6-8-16-7-2-3-9-17(16)20/h2-12,15,22H,13-14H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells |
Bioorg Med Chem Lett 14: 5499-502 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.003
BindingDB Entry DOI: 10.7270/Q2SB457X |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM21341
(2-[1-(benzenesulfonyl)-1H-indol-3-yl]ethan-1-amine...)Show InChI InChI=1S/C16H16N2O2S/c17-11-10-13-12-18(16-9-5-4-8-15(13)16)21(19,20)14-6-2-1-3-7-14/h1-9,12H,10-11,17H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 10.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells |
Bioorg Med Chem Lett 14: 5499-502 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.003
BindingDB Entry DOI: 10.7270/Q2SB457X |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM21366
((2-{3-[(3-fluorobenzene)sulfonyl]-1H-indol-1-yl}et...)Show InChI InChI=1S/C18H19FN2O2S/c1-20(2)10-11-21-13-18(16-8-3-4-9-17(16)21)24(22,23)15-7-5-6-14(19)12-15/h3-9,12-13H,10-11H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells |
Bioorg Med Chem Lett 14: 5499-502 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.003
BindingDB Entry DOI: 10.7270/Q2SB457X |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50155138
(CHEMBL360181 | [2-(3-Benzenesulfonyl-indol-1-yl)-e...)Show InChI InChI=1S/C17H18N2O2S/c1-18-11-12-19-13-17(15-9-5-6-10-16(15)19)22(20,21)14-7-3-2-4-8-14/h2-10,13,18H,11-12H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 15.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells |
Bioorg Med Chem Lett 14: 5499-502 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.003
BindingDB Entry DOI: 10.7270/Q2SB457X |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50155133
(CHEMBL425714 | Dimethyl-{2-[3-(2-trifluoromethoxy-...)Show SMILES CN(C)CCn1cc(c2ccccc12)S(=O)(=O)c1ccccc1OC(F)(F)F Show InChI InChI=1S/C19H19F3N2O3S/c1-23(2)11-12-24-13-18(14-7-3-4-8-15(14)24)28(25,26)17-10-6-5-9-16(17)27-19(20,21)22/h3-10,13H,11-12H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells |
Bioorg Med Chem Lett 14: 5499-502 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.003
BindingDB Entry DOI: 10.7270/Q2SB457X |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50155139
(CHEMBL445652 | [2-(3-Benzenesulfonyl-2-methyl-indo...)Show InChI InChI=1S/C19H22N2O2S/c1-15-19(24(22,23)16-9-5-4-6-10-16)17-11-7-8-12-18(17)21(15)14-13-20(2)3/h4-12H,13-14H2,1-3H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells |
Bioorg Med Chem Lett 14: 5499-502 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.003
BindingDB Entry DOI: 10.7270/Q2SB457X |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50155128
(CHEMBL183203 | N,N-dimethyl-2-(3-(phenylsulfonyl)-...)Show InChI InChI=1S/C18H20N2O2S/c1-19(2)12-13-20-14-18(16-10-6-7-11-17(16)20)23(21,22)15-8-4-3-5-9-15/h3-11,14H,12-13H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells |
Bioorg Med Chem Lett 14: 5499-502 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.003
BindingDB Entry DOI: 10.7270/Q2SB457X |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50155143
(CHEMBL184640 | [2-(3-Benzenesulfonyl-6-methoxy-ind...)Show SMILES COc1ccc2c(cn(CCN(C)C)c2c1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C19H22N2O3S/c1-20(2)11-12-21-14-19(17-10-9-15(24-3)13-18(17)21)25(22,23)16-7-5-4-6-8-16/h4-10,13-14H,11-12H2,1-3H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells |
Bioorg Med Chem Lett 14: 5499-502 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.003
BindingDB Entry DOI: 10.7270/Q2SB457X |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50155127
(CHEMBL185850 | [2-(3-Benzenesulfonyl-7-methoxy-ind...)Show SMILES COc1cccc2c(cn(CCN(C)C)c12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C19H22N2O3S/c1-20(2)12-13-21-14-18(16-10-7-11-17(24-3)19(16)21)25(22,23)15-8-5-4-6-9-15/h4-11,14H,12-13H2,1-3H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells |
Bioorg Med Chem Lett 14: 5499-502 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.003
BindingDB Entry DOI: 10.7270/Q2SB457X |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50155140
(2-(3-(phenylsulfonyl)-1H-indol-1-yl)ethanamine | 2...)Show InChI InChI=1S/C16H16N2O2S/c17-10-11-18-12-16(14-8-4-5-9-15(14)18)21(19,20)13-6-2-1-3-7-13/h1-9,12H,10-11,17H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells |
Bioorg Med Chem Lett 14: 5499-502 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.003
BindingDB Entry DOI: 10.7270/Q2SB457X |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50155131
(2-(3-Benzenesulfonyl-5-fluoro-indol-1-yl)-ethylami...)Show InChI InChI=1S/C16H15FN2O2S/c17-12-6-7-15-14(10-12)16(11-19(15)9-8-18)22(20,21)13-4-2-1-3-5-13/h1-7,10-11H,8-9,18H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells |
Bioorg Med Chem Lett 14: 5499-502 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.003
BindingDB Entry DOI: 10.7270/Q2SB457X |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50155141
(CHEMBL184671 | [2-(3-Benzenesulfonyl-6-chloro-indo...)Show SMILES CN(C)CCn1cc(c2ccc(Cl)cc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H19ClN2O2S/c1-20(2)10-11-21-13-18(16-9-8-14(19)12-17(16)21)24(22,23)15-6-4-3-5-7-15/h3-9,12-13H,10-11H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 42 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells |
Bioorg Med Chem Lett 14: 5499-502 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.003
BindingDB Entry DOI: 10.7270/Q2SB457X |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50155137
(CHEMBL360642 | [2-(3-Benzenesulfonyl-5-fluoro-indo...)Show InChI InChI=1S/C18H19FN2O2S/c1-20(2)10-11-21-13-18(16-12-14(19)8-9-17(16)21)24(22,23)15-6-4-3-5-7-15/h3-9,12-13H,10-11H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 44 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells |
Bioorg Med Chem Lett 14: 5499-502 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.003
BindingDB Entry DOI: 10.7270/Q2SB457X |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50155134
(CHEMBL359967 | [2-(3-Benzenesulfonyl-6-fluoro-indo...)Show InChI InChI=1S/C18H19FN2O2S/c1-20(2)10-11-21-13-18(16-9-8-14(19)12-17(16)21)24(22,23)15-6-4-3-5-7-15/h3-9,12-13H,10-11H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 46 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells |
Bioorg Med Chem Lett 14: 5499-502 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.003
BindingDB Entry DOI: 10.7270/Q2SB457X |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50155136
(CHEMBL185672 | Dimethyl-{2-[3-(toluene-4-sulfonyl)...)Show InChI InChI=1S/C19H22N2O2S/c1-15-8-10-16(11-9-15)24(22,23)19-14-21(13-12-20(2)3)18-7-5-4-6-17(18)19/h4-11,14H,12-13H2,1-3H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 57 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells |
Bioorg Med Chem Lett 14: 5499-502 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.003
BindingDB Entry DOI: 10.7270/Q2SB457X |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50155132
(CHEMBL184066 | [2-(3-Benzenesulfonyl-4-fluoro-indo...)Show InChI InChI=1S/C18H19FN2O2S/c1-20(2)11-12-21-13-17(18-15(19)9-6-10-16(18)21)24(22,23)14-7-4-3-5-8-14/h3-10,13H,11-12H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 98 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells |
Bioorg Med Chem Lett 14: 5499-502 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.003
BindingDB Entry DOI: 10.7270/Q2SB457X |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50155126
(2-(3-Benzenesulfonyl-6-chloro-indol-1-yl)-ethylami...)Show InChI InChI=1S/C16H15ClN2O2S/c17-12-6-7-14-15(10-12)19(9-8-18)11-16(14)22(20,21)13-4-2-1-3-5-13/h1-7,10-11H,8-9,18H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 141 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells |
Bioorg Med Chem Lett 14: 5499-502 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.003
BindingDB Entry DOI: 10.7270/Q2SB457X |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50155129
(CHEMBL364351 | Dimethyl-[2-(3-phenylmethanesulfony...)Show InChI InChI=1S/C19H22N2O2S/c1-20(2)12-13-21-14-19(17-10-6-7-11-18(17)21)24(22,23)15-16-8-4-3-5-9-16/h3-11,14H,12-13,15H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells |
Bioorg Med Chem Lett 14: 5499-502 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.003
BindingDB Entry DOI: 10.7270/Q2SB457X |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50155127
(CHEMBL185850 | [2-(3-Benzenesulfonyl-7-methoxy-ind...)Show SMILES COc1cccc2c(cn(CCN(C)C)c12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C19H22N2O3S/c1-20(2)12-13-21-14-18(16-10-7-11-17(24-3)19(16)21)25(22,23)15-8-5-4-6-9-15/h4-11,14H,12-13H2,1-3H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells in cAMP assay |
Bioorg Med Chem Lett 14: 5499-502 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.003
BindingDB Entry DOI: 10.7270/Q2SB457X |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50155130
(CHEMBL185958 | Dimethyl-{2-[3-(naphthalene-1-sulfo...)Show SMILES CN(C)CCn1cc(c2ccccc12)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C22H22N2O2S/c1-23(2)14-15-24-16-22(19-11-5-6-12-20(19)24)27(25,26)21-13-7-9-17-8-3-4-10-18(17)21/h3-13,16H,14-15H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells in cAMP assay |
Bioorg Med Chem Lett 14: 5499-502 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.003
BindingDB Entry DOI: 10.7270/Q2SB457X |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50155135
(CHEMBL184652 | Methyl-{2-[3-(naphthalene-1-sulfony...)Show InChI InChI=1S/C21H20N2O2S/c1-22-13-14-23-15-21(18-10-4-5-11-19(18)23)26(24,25)20-12-6-8-16-7-2-3-9-17(16)20/h2-12,15,22H,13-14H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 359 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells in cAMP assay |
Bioorg Med Chem Lett 14: 5499-502 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.003
BindingDB Entry DOI: 10.7270/Q2SB457X |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50155133
(CHEMBL425714 | Dimethyl-{2-[3-(2-trifluoromethoxy-...)Show SMILES CN(C)CCn1cc(c2ccccc12)S(=O)(=O)c1ccccc1OC(F)(F)F Show InChI InChI=1S/C19H19F3N2O3S/c1-23(2)11-12-24-13-18(14-7-3-4-8-15(14)24)28(25,26)17-10-6-5-9-16(17)27-19(20,21)22/h3-10,13H,11-12H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 792 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells in cAMP assay |
Bioorg Med Chem Lett 14: 5499-502 (2004)
Article DOI: 10.1016/j.bmcl.2004.09.003
BindingDB Entry DOI: 10.7270/Q2SB457X |
More data for this
Ligand-Target Pair | |
Search and Browse
