Affinity Data by PubMed id=15537349

PubMed code 15537349

Found 18 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cholinesterase (Homo sapiens (Human))	BDBM10955 ((2S,6R)-3-methyl-8-oxa-3-azatricyclo[7.4.0.0^{2,6}...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26	n/a	n/a	n/a	n/a	8.0	37
University of Bologna					Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...				J Med Chem 47: 5945-52 (2004) Article DOI: 10.1021/jm049782n BindingDB Entry DOI: 10.7270/Q2668BD3
University of Bologna					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM10953 ((2S,6R)-3-methyl-8-thia-3-azatricyclo[7.4.0.0^{2,6...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.11	n/a	n/a	n/a	n/a	8.0	37
University of Bologna					Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...				J Med Chem 47: 5945-52 (2004) Article DOI: 10.1021/jm049782n BindingDB Entry DOI: 10.7270/Q2668BD3
University of Bologna					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM10953 ((2S,6R)-3-methyl-8-thia-3-azatricyclo[7.4.0.0^{2,6...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10.5	n/a	n/a	n/a	n/a	8.0	37
University of Bologna					Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...				J Med Chem 47: 5945-52 (2004) Article DOI: 10.1021/jm049782n BindingDB Entry DOI: 10.7270/Q2668BD3
University of Bologna					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM10952 ((2S,6R)-3-methyl-3-azatricyclo[7.4.0.0^{2,6}]tride...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17.3	n/a	n/a	n/a	n/a	8.0	37
University of Bologna					Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...				J Med Chem 47: 5945-52 (2004) Article DOI: 10.1021/jm049782n BindingDB Entry DOI: 10.7270/Q2668BD3
University of Bologna					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM10955 ((2S,6R)-3-methyl-8-oxa-3-azatricyclo[7.4.0.0^{2,6}...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20.3	n/a	n/a	n/a	n/a	8.0	37
University of Bologna					Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...				J Med Chem 47: 5945-52 (2004) Article DOI: 10.1021/jm049782n BindingDB Entry DOI: 10.7270/Q2668BD3
University of Bologna					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM10952 ((2S,6R)-3-methyl-3-azatricyclo[7.4.0.0^{2,6}]tride...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24.5	n/a	n/a	n/a	n/a	8.0	37
University of Bologna					Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...				J Med Chem 47: 5945-52 (2004) Article DOI: 10.1021/jm049782n BindingDB Entry DOI: 10.7270/Q2668BD3
University of Bologna					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM10951 ((2S,6R)-3-methyl-8-oxa-3-azatricyclo[7.4.0.0^{2,6}...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	8.0	37
University of Bologna					Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...				J Med Chem 47: 5945-52 (2004) Article DOI: 10.1021/jm049782n BindingDB Entry DOI: 10.7270/Q2668BD3
University of Bologna					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM10957 ((2S,6R)-3-methyl-3-azatricyclo[7.4.0.0^{2,6}]tride...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30.3	n/a	n/a	n/a	n/a	8.0	37
University of Bologna					Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...				J Med Chem 47: 5945-52 (2004) Article DOI: 10.1021/jm049782n BindingDB Entry DOI: 10.7270/Q2668BD3
University of Bologna					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM10956 ((2S,6R)-3-methyl-8-oxa-3-azatricyclo[7.4.0.0^{2,6}...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44.4	n/a	n/a	n/a	n/a	8.0	37
University of Bologna					Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...				J Med Chem 47: 5945-52 (2004) Article DOI: 10.1021/jm049782n BindingDB Entry DOI: 10.7270/Q2668BD3
University of Bologna					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM10951 ((2S,6R)-3-methyl-8-oxa-3-azatricyclo[7.4.0.0^{2,6}...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59.4	n/a	n/a	n/a	n/a	8.0	37
University of Bologna					Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...				J Med Chem 47: 5945-52 (2004) Article DOI: 10.1021/jm049782n BindingDB Entry DOI: 10.7270/Q2668BD3
University of Bologna					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM10950 (3-[1-(dimethylamino)ethyl]phenyl N-methylcarbamate...) Show SMILES CNC(=O)Oc1cccc(c1)C(C)N(C)C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	8.0	37
University of Bologna					Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...				J Med Chem 47: 5945-52 (2004) Article DOI: 10.1021/jm049782n BindingDB Entry DOI: 10.7270/Q2668BD3
University of Bologna					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM10954 ((2S,6R)-3-methyl-8-oxa-3-azatricyclo[7.4.0.0^{2,6}...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	209	n/a	n/a	n/a	n/a	8.0	37
University of Bologna					Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...				J Med Chem 47: 5945-52 (2004) Article DOI: 10.1021/jm049782n BindingDB Entry DOI: 10.7270/Q2668BD3
University of Bologna					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM10620 ((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	301	n/a	n/a	n/a	n/a	8.0	37
University of Bologna					Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...				J Med Chem 47: 5945-52 (2004) Article DOI: 10.1021/jm049782n BindingDB Entry DOI: 10.7270/Q2668BD3
University of Bologna					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM10957 ((2S,6R)-3-methyl-3-azatricyclo[7.4.0.0^{2,6}]tride...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	393	n/a	n/a	n/a	n/a	8.0	37
University of Bologna					Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...				J Med Chem 47: 5945-52 (2004) Article DOI: 10.1021/jm049782n BindingDB Entry DOI: 10.7270/Q2668BD3
University of Bologna					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM10950 (3-[1-(dimethylamino)ethyl]phenyl N-methylcarbamate...) Show SMILES CNC(=O)Oc1cccc(c1)C(C)N(C)C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	406	n/a	n/a	n/a	n/a	8.0	37
University of Bologna					Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...				J Med Chem 47: 5945-52 (2004) Article DOI: 10.1021/jm049782n BindingDB Entry DOI: 10.7270/Q2668BD3
University of Bologna					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM10956 ((2S,6R)-3-methyl-8-oxa-3-azatricyclo[7.4.0.0^{2,6}...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	8.0	37
University of Bologna					Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...				J Med Chem 47: 5945-52 (2004) Article DOI: 10.1021/jm049782n BindingDB Entry DOI: 10.7270/Q2668BD3
University of Bologna					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM10620 ((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	1.54E+3	n/a	n/a	n/a	n/a	8.0	37
University of Bologna					Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...				J Med Chem 47: 5945-52 (2004) Article DOI: 10.1021/jm049782n BindingDB Entry DOI: 10.7270/Q2668BD3
University of Bologna					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM10954 ((2S,6R)-3-methyl-8-oxa-3-azatricyclo[7.4.0.0^{2,6}...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.87E+3	n/a	n/a	n/a	n/a	8.0	37
University of Bologna					Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...				J Med Chem 47: 5945-52 (2004) Article DOI: 10.1021/jm049782n BindingDB Entry DOI: 10.7270/Q2668BD3
University of Bologna					More data for this Ligand-Target Pair

* indicates data uncertainty>20%