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PubMed code 15582404

Compile data set for download or QSAR
Found 68 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157003
PNG
(CHEMBL369352 | N-Cyclopropyl-N-[1-(3,3-diphenyl-pr...)
Show SMILES NS(=O)(=O)c1ccc(CC(=O)N(C2CC2)C2CCN(CCC(c3ccccc3)c3ccccc3)CC2)cc1
Show InChI InChI=1S/C31H37N3O3S/c32-38(36,37)29-15-11-24(12-16-29)23-31(35)34(27-13-14-27)28-17-20-33(21-18-28)22-19-30(25-7-3-1-4-8-25)26-9-5-2-6-10-26/h1-12,15-16,27-28,30H,13-14,17-23H2,(H2,32,36,37)
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n/an/a 33n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157002
PNG
(1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-1-ethyl...)
Show SMILES CCN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)NCc1cccc(C)c1
Show InChI InChI=1S/C31H39N3O/c1-3-34(31(35)32-24-26-12-10-11-25(2)23-26)29-17-20-33(21-18-29)22-19-30(27-13-6-4-7-14-27)28-15-8-5-9-16-28/h4-16,23,29-30H,3,17-22,24H2,1-2H3,(H,32,35)
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n/an/a 35n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157000
PNG
(CHEMBL180155 | N-Allyl-N-[1-(3,3-diphenyl-propyl)-...)
Show SMILES CS(=O)(=O)c1ccc(CC(=O)N(CC=C)C2CCN(CCC(c3ccccc3)c3ccccc3)CC2)cc1
Show InChI InChI=1S/C32H38N2O3S/c1-3-21-34(32(35)25-26-14-16-30(17-15-26)38(2,36)37)29-18-22-33(23-19-29)24-20-31(27-10-6-4-7-11-27)28-12-8-5-9-13-28/h3-17,29,31H,1,18-25H2,2H3
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n/an/a 37n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157030
PNG
(CHEMBL179877 | N-[1-(3,3-Diphenyl-propyl)-piperidi...)
Show SMILES CCN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C30H37N3O3S/c1-2-33(30(34)23-24-13-15-28(16-14-24)37(31,35)36)27-17-20-32(21-18-27)22-19-29(25-9-5-3-6-10-25)26-11-7-4-8-12-26/h3-16,27,29H,2,17-23H2,1H3,(H2,31,35,36)
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n/an/a 38n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156969
PNG
(1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-1-ethyl...)
Show SMILES CCN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)NCc1ccc(OC)cc1
Show InChI InChI=1S/C31H39N3O2/c1-3-34(31(35)32-24-25-14-16-29(36-2)17-15-25)28-18-21-33(22-19-28)23-20-30(26-10-6-4-7-11-26)27-12-8-5-9-13-27/h4-17,28,30H,3,18-24H2,1-2H3,(H,32,35)
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n/an/a 42n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156989
PNG
(2-(4-Dimethylsulfamoyl-phenyl)-N-[1-(3,3-diphenyl-...)
Show SMILES CN(C)S(=O)(=O)c1ccc(CC(=O)N(C)C2CCN(CCC(c3ccccc3)c3ccccc3)CC2)cc1
Show InChI InChI=1S/C31H39N3O3S/c1-32(2)38(36,37)29-16-14-25(15-17-29)24-31(35)33(3)28-18-21-34(22-19-28)23-20-30(26-10-6-4-7-11-26)27-12-8-5-9-13-27/h4-17,28,30H,18-24H2,1-3H3
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n/an/a 46n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157012
PNG
(1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-1-ethyl...)
Show SMILES CCN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)NCc1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C31H39N3O3S/c1-3-34(31(35)32-24-25-14-16-29(17-15-25)38(2,36)37)28-18-21-33(22-19-28)23-20-30(26-10-6-4-7-11-26)27-12-8-5-9-13-27/h4-17,28,30H,3,18-24H2,1-2H3,(H,32,35)
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n/an/a 49n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157026
PNG
(CHEMBL182074 | N-Cyclopropyl-N-[1-(3,3-diphenyl-pr...)
Show SMILES CS(=O)(=O)c1ccc(CC(=O)N(C2CC2)C2CCN(CCC(c3ccccc3)c3ccccc3)CC2)cc1
Show InChI InChI=1S/C32H38N2O3S/c1-38(36,37)30-16-12-25(13-17-30)24-32(35)34(28-14-15-28)29-18-21-33(22-19-29)23-20-31(26-8-4-2-5-9-26)27-10-6-3-7-11-27/h2-13,16-17,28-29,31H,14-15,18-24H2,1H3
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n/an/a 51n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156998
PNG
(2-(4-Cyano-phenyl)-N-[1-(3,3-diphenyl-propyl)-pipe...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1ccc(cc1)C#N
Show InChI InChI=1S/C30H33N3O/c1-32(30(34)22-24-12-14-25(23-31)15-13-24)28-16-19-33(20-17-28)21-18-29(26-8-4-2-5-9-26)27-10-6-3-7-11-27/h2-15,28-29H,16-22H2,1H3
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n/an/a 60n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156974
PNG
(3-Benzyl-1-[1-(3,3-diphenyl-propyl)-piperidin-4-yl...)
Show SMILES CCN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)NCc1ccccc1
Show InChI InChI=1S/C30H37N3O/c1-2-33(30(34)31-24-25-12-6-3-7-13-25)28-18-21-32(22-19-28)23-20-29(26-14-8-4-9-15-26)27-16-10-5-11-17-27/h3-17,28-29H,2,18-24H2,1H3,(H,31,34)
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n/an/a 62n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157004
PNG
(2-(4-Cyano-phenyl)-N-[1-(3,3-diphenyl-propyl)-pipe...)
Show SMILES CCN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1ccc(cc1)C#N
Show InChI InChI=1S/C31H35N3O/c1-2-34(31(35)23-25-13-15-26(24-32)16-14-25)29-17-20-33(21-18-29)22-19-30(27-9-5-3-6-10-27)28-11-7-4-8-12-28/h3-16,29-30H,2,17-23H2,1H3
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n/an/a 66n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157032
PNG
(CHEMBL369311 | N-[1-(3,3-Diphenyl-propyl)-piperidi...)
Show SMILES CCN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C31H38N2O3S/c1-3-33(31(34)24-25-14-16-29(17-15-25)37(2,35)36)28-18-21-32(22-19-28)23-20-30(26-10-6-4-7-11-26)27-12-8-5-9-13-27/h4-17,28,30H,3,18-24H2,1-2H3
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n/an/a 76n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157023
PNG
(CHEMBL181913 | N-[1-(3,3-Diphenyl-propyl)-piperidi...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C29H35N3O3S/c1-31(29(33)22-23-12-14-27(15-13-23)36(30,34)35)26-16-19-32(20-17-26)21-18-28(24-8-4-2-5-9-24)25-10-6-3-7-11-25/h2-15,26,28H,16-22H2,1H3,(H2,30,34,35)
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n/an/a 91n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157018
PNG
(3-Benzyl-1-[1-(3,3-diphenyl-propyl)-piperidin-4-yl...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)NCc1ccccc1
Show InChI InChI=1S/C29H35N3O/c1-31(29(33)30-23-24-11-5-2-6-12-24)27-17-20-32(21-18-27)22-19-28(25-13-7-3-8-14-25)26-15-9-4-10-16-26/h2-16,27-28H,17-23H2,1H3,(H,30,33)
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n/an/a 100n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156982
PNG
(1-Allyl-1-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]...)
Show SMILES COc1ccc(CNC(=O)N(CC=C)C2CCN(CCC(c3ccccc3)c3ccccc3)CC2)cc1
Show InChI InChI=1S/C32H39N3O2/c1-3-21-35(32(36)33-25-26-14-16-30(37-2)17-15-26)29-18-22-34(23-19-29)24-20-31(27-10-6-4-7-11-27)28-12-8-5-9-13-28/h3-17,29,31H,1,18-25H2,2H3,(H,33,36)
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n/an/a 110n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157016
PNG
(CHEMBL360106 | N-[1-(3,3-Diphenyl-propyl)-piperidi...)
Show SMILES CCN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C30H35N3O3/c1-2-32(30(34)23-24-13-15-28(16-14-24)33(35)36)27-17-20-31(21-18-27)22-19-29(25-9-5-3-6-10-25)26-11-7-4-8-12-26/h3-16,27,29H,2,17-23H2,1H3
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n/an/a 110n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156980
PNG
(CHEMBL360044 | N-[1-(3,3-Diphenyl-propyl)-piperidi...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C29H33N3O3/c1-30(29(33)22-23-12-14-27(15-13-23)32(34)35)26-16-19-31(20-17-26)21-18-28(24-8-4-2-5-9-24)25-10-6-3-7-11-25/h2-15,26,28H,16-22H2,1H3
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n/an/a 150n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157019
PNG
(CHEMBL426960 | N-Allyl-N-[1-(3,3-diphenyl-propyl)-...)
Show SMILES [O-][N+](=O)c1ccc(CC(=O)N(CC=C)C2CCN(CCC(c3ccccc3)c3ccccc3)CC2)cc1
Show InChI InChI=1S/C31H35N3O3/c1-2-20-33(31(35)24-25-13-15-29(16-14-25)34(36)37)28-17-21-32(22-18-28)23-19-30(26-9-5-3-6-10-26)27-11-7-4-8-12-27/h2-16,28,30H,1,17-24H2
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AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157009
PNG
(1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-3-(4-fl...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Nc1ccc(F)cc1
Show InChI InChI=1S/C28H32FN3O/c1-31(28(33)30-25-14-12-24(29)13-15-25)26-16-19-32(20-17-26)21-18-27(22-8-4-2-5-9-22)23-10-6-3-7-11-23/h2-15,26-27H,16-21H2,1H3,(H,30,33)
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AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157015
PNG
(1-Allyl-1-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]...)
Show SMILES Cc1cccc(CNC(=O)N(CC=C)C2CCN(CCC(c3ccccc3)c3ccccc3)CC2)c1
Show InChI InChI=1S/C32H39N3O/c1-3-20-35(32(36)33-25-27-12-10-11-26(2)24-27)30-17-21-34(22-18-30)23-19-31(28-13-6-4-7-14-28)29-15-8-5-9-16-29/h3-16,24,30-31H,1,17-23,25H2,2H3,(H,33,36)
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AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156972
PNG
(CHEMBL182684 | N-[1-(3,3-Diphenyl-propyl)-piperidi...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C30H33F3N2O2/c1-34(29(36)22-23-12-14-27(15-13-23)37-30(31,32)33)26-16-19-35(20-17-26)21-18-28(24-8-4-2-5-9-24)25-10-6-3-7-11-25/h2-15,26,28H,16-22H2,1H3
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AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156970
PNG
(CHEMBL182817 | N-[1-(3,3-Diphenyl-propyl)-piperidi...)
Show SMILES CCN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C31H35F3N2O2/c1-2-36(30(37)23-24-13-15-28(16-14-24)38-31(32,33)34)27-17-20-35(21-18-27)22-19-29(25-9-5-3-6-10-25)26-11-7-4-8-12-26/h3-16,27,29H,2,17-23H2,1H3
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AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156992
PNG
(CHEMBL182929 | N-Cyclopropyl-N-[1-(3,3-diphenyl-pr...)
Show SMILES [O-][N+](=O)c1ccc(CC(=O)N(C2CC2)C2CCN(CCC(c3ccccc3)c3ccccc3)CC2)cc1
Show InChI InChI=1S/C31H35N3O3/c35-31(23-24-11-13-29(14-12-24)34(36)37)33(27-15-16-27)28-17-20-32(21-18-28)22-19-30(25-7-3-1-4-8-25)26-9-5-2-6-10-26/h1-14,27-28,30H,15-23H2
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AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156975
PNG
(1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-1-ethyl...)
Show SMILES CCN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Nc1ccc(C)cc1
Show InChI InChI=1S/C30H37N3O/c1-3-33(30(34)31-27-16-14-24(2)15-17-27)28-18-21-32(22-19-28)23-20-29(25-10-6-4-7-11-25)26-12-8-5-9-13-26/h4-17,28-29H,3,18-23H2,1-2H3,(H,31,34)
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AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157025
PNG
(CHEMBL182083 | N-Allyl-N-[1-(3,3-diphenyl-propyl)-...)
Show SMILES FC(F)(F)Oc1ccc(CC(=O)N(CC=C)C2CCN(CCC(c3ccccc3)c3ccccc3)CC2)cc1
Show InChI InChI=1S/C32H35F3N2O2/c1-2-20-37(31(38)24-25-13-15-29(16-14-25)39-32(33,34)35)28-17-21-36(22-18-28)23-19-30(26-9-5-3-6-10-26)27-11-7-4-8-12-27/h2-16,28,30H,1,17-24H2
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AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157028
PNG
(3-(3,4-Dichloro-phenyl)-1-[1-(3,3-diphenyl-propyl)...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Nc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C28H31Cl2N3O/c1-32(28(34)31-23-12-13-26(29)27(30)20-23)24-14-17-33(18-15-24)19-16-25(21-8-4-2-5-9-21)22-10-6-3-7-11-22/h2-13,20,24-25H,14-19H2,1H3,(H,31,34)
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AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157008
PNG
(CHEMBL360524 | N-[1-(3,3-Diphenyl-propyl)-piperidi...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C30H33F3N2O/c1-34(29(36)22-23-12-14-26(15-13-23)30(31,32)33)27-16-19-35(20-17-27)21-18-28(24-8-4-2-5-9-24)25-10-6-3-7-11-25/h2-15,27-28H,16-22H2,1H3
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AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50156978
PNG
(2-(4-Dimethylsulfamoyl-phenyl)-N-[1-(3,3-diphenyl-...)
Show SMILES CCN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1ccc(cc1)S(=O)(=O)N(C)C
Show InChI InChI=1S/C32H41N3O3S/c1-4-35(32(36)25-26-15-17-30(18-16-26)39(37,38)33(2)3)29-19-22-34(23-20-29)24-21-31(27-11-7-5-8-12-27)28-13-9-6-10-14-28/h5-18,29,31H,4,19-25H2,1-3H3
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AstraZeneca

Curated by ChEMBL


Assay Description
Inhibitory concentration against human Muscarinic acetylcholine receptor M1

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157010
PNG
(CHEMBL183709 | N-[1-(3,3-Diphenyl-propyl)-piperidi...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1ccc(O)cc1
Show InChI InChI=1S/C29H34N2O2/c1-30(29(33)22-23-12-14-27(32)15-13-23)26-16-19-31(20-17-26)21-18-28(24-8-4-2-5-9-24)25-10-6-3-7-11-25/h2-15,26,28,32H,16-22H2,1H3
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AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156986
PNG
(CHEMBL183409 | N-[1-(3,3-Diphenyl-propyl)-piperidi...)
Show SMILES CSc1ccc(CC(=O)N(C)C2CCN(CCC(c3ccccc3)c3ccccc3)CC2)cc1
Show InChI InChI=1S/C30H36N2OS/c1-31(30(33)23-24-13-15-28(34-2)16-14-24)27-17-20-32(21-18-27)22-19-29(25-9-5-3-6-10-25)26-11-7-4-8-12-26/h3-16,27,29H,17-23H2,1-2H3
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AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156987
PNG
(CHEMBL180498 | N-[1-(3,3-Diphenyl-propyl)-piperidi...)
Show SMILES COc1ccc(CC(=O)N(C)C2CCN(CCC(c3ccccc3)c3ccccc3)CC2)cc1
Show InChI InChI=1S/C30H36N2O2/c1-31(30(33)23-24-13-15-28(34-2)16-14-24)27-17-20-32(21-18-27)22-19-29(25-9-5-3-6-10-25)26-11-7-4-8-12-26/h3-16,27,29H,17-23H2,1-2H3
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AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157021
PNG
(2-(4-Bromo-phenyl)-N-[1-(3,3-diphenyl-propyl)-pipe...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1ccc(Br)cc1
Show InChI InChI=1S/C29H33BrN2O/c1-31(29(33)22-23-12-14-26(30)15-13-23)27-16-19-32(20-17-27)21-18-28(24-8-4-2-5-9-24)25-10-6-3-7-11-25/h2-15,27-28H,16-22H2,1H3
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AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156981
PNG
(4-({[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-methy...)
Show SMILES COC(=O)c1ccc(CC(=O)N(C)C2CCN(CCC(c3ccccc3)c3ccccc3)CC2)cc1
Show InChI InChI=1S/C31H36N2O3/c1-32(30(34)23-24-13-15-27(16-14-24)31(35)36-2)28-17-20-33(21-18-28)22-19-29(25-9-5-3-6-10-25)26-11-7-4-8-12-26/h3-16,28-29H,17-23H2,1-2H3
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AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157033
PNG
(2-(3,4-Dimethoxy-phenyl)-N-[1-(3,3-diphenyl-propyl...)
Show SMILES COc1ccc(CC(=O)N(C)C2CCN(CCC(c3ccccc3)c3ccccc3)CC2)cc1OC
Show InChI InChI=1S/C31H38N2O3/c1-32(31(34)23-24-14-15-29(35-2)30(22-24)36-3)27-16-19-33(20-17-27)21-18-28(25-10-6-4-7-11-25)26-12-8-5-9-13-26/h4-15,22,27-28H,16-21,23H2,1-3H3
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AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156999
PNG
(CHEMBL180334 | N-[1-(3,3-Diphenyl-propyl)-piperidi...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1ccc(F)cc1
Show InChI InChI=1S/C29H33FN2O/c1-31(29(33)22-23-12-14-26(30)15-13-23)27-16-19-32(20-17-27)21-18-28(24-8-4-2-5-9-24)25-10-6-3-7-11-25/h2-15,27-28H,16-22H2,1H3
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AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157027
PNG
(CHEMBL183769 | N-[1-(3,3-Diphenyl-propyl)-piperidi...)
Show SMILES COc1cccc(CC(=O)N(C)C2CCN(CCC(c3ccccc3)c3ccccc3)CC2)c1
Show InChI InChI=1S/C30H36N2O2/c1-31(30(33)23-24-10-9-15-28(22-24)34-2)27-16-19-32(20-17-27)21-18-29(25-11-5-3-6-12-25)26-13-7-4-8-14-26/h3-15,22,27,29H,16-21,23H2,1-2H3
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AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156984
PNG
(2-(4-Acetylamino-phenyl)-N-[1-(3,3-diphenyl-propyl...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1ccc(NC(C)=O)cc1
Show InChI InChI=1S/C31H37N3O2/c1-24(35)32-28-15-13-25(14-16-28)23-31(36)33(2)29-17-20-34(21-18-29)22-19-30(26-9-5-3-6-10-26)27-11-7-4-8-12-27/h3-16,29-30H,17-23H2,1-2H3,(H,32,35)
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n/an/a 680n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157014
PNG
(2-(3,4-Difluoro-phenyl)-N-[1-(3,3-diphenyl-propyl)...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1ccc(F)c(F)c1
Show InChI InChI=1S/C29H32F2N2O/c1-32(29(34)21-22-12-13-27(30)28(31)20-22)25-14-17-33(18-15-25)19-16-26(23-8-4-2-5-9-23)24-10-6-3-7-11-24/h2-13,20,25-26H,14-19,21H2,1H3
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n/an/a 690n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156977
PNG
(CHEMBL367586 | N-[1-(3,3-Diphenyl-propyl)-piperidi...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1ccccc1
Show InChI InChI=1S/C29H34N2O/c1-30(29(32)23-24-11-5-2-6-12-24)27-17-20-31(21-18-27)22-19-28(25-13-7-3-8-14-25)26-15-9-4-10-16-26/h2-16,27-28H,17-23H2,1H3
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n/an/a 770n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157007
PNG
(2-(3,4-Dichloro-phenyl)-N-[1-(3,3-diphenyl-propyl)...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C29H32Cl2N2O/c1-32(29(34)21-22-12-13-27(30)28(31)20-22)25-14-17-33(18-15-25)19-16-26(23-8-4-2-5-9-23)24-10-6-3-7-11-24/h2-13,20,25-26H,14-19,21H2,1H3
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n/an/a 780n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156995
PNG
(2-(4-Chloro-phenyl)-N-[1-(3,3-diphenyl-propyl)-pip...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1ccc(Cl)cc1
Show InChI InChI=1S/C29H33ClN2O/c1-31(29(33)22-23-12-14-26(30)15-13-23)27-16-19-32(20-17-27)21-18-28(24-8-4-2-5-9-24)25-10-6-3-7-11-25/h2-15,27-28H,16-22H2,1H3
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n/an/a 800n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50156978
PNG
(2-(4-Dimethylsulfamoyl-phenyl)-N-[1-(3,3-diphenyl-...)
Show SMILES CCN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1ccc(cc1)S(=O)(=O)N(C)C
Show InChI InChI=1S/C32H41N3O3S/c1-4-35(32(36)25-26-15-17-30(18-16-26)39(37,38)33(2)3)29-19-22-34(23-20-29)24-21-31(27-11-7-5-8-12-27)28-13-9-6-10-14-28/h5-18,29,31H,4,19-25H2,1-3H3
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n/an/a 800n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibitory concentration against human 5-hydroxytryptamine 2A receptor

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156977
PNG
(CHEMBL367586 | N-[1-(3,3-Diphenyl-propyl)-piperidi...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1ccccc1
Show InChI InChI=1S/C29H34N2O/c1-30(29(32)23-24-11-5-2-6-12-24)27-17-20-31(21-18-27)22-19-28(25-13-7-3-8-14-25)26-15-9-4-10-16-26/h2-16,27-28H,17-23H2,1H3
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n/an/a 810n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156983
PNG
(CHEMBL427144 | N-[1-(3,3-Diphenyl-propyl)-piperidi...)
Show SMILES COc1cc(OC)c(OC)cc1CC(=O)N(C)C1CCN(CCC(c2ccccc2)c2ccccc2)CC1
Show InChI InChI=1S/C32H40N2O4/c1-33(32(35)22-26-21-30(37-3)31(38-4)23-29(26)36-2)27-15-18-34(19-16-27)20-17-28(24-11-7-5-8-12-24)25-13-9-6-10-14-25/h5-14,21,23,27-28H,15-20,22H2,1-4H3
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n/an/a 1.10E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157013
PNG
(CHEMBL183514 | N-[1-(3,3-Diphenyl-propyl)-piperidi...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1cccc(F)c1
Show InChI InChI=1S/C29H33FN2O/c1-31(29(33)22-23-9-8-14-26(30)21-23)27-15-18-32(19-16-27)20-17-28(24-10-4-2-5-11-24)25-12-6-3-7-13-25/h2-14,21,27-28H,15-20,22H2,1H3
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n/an/a 1.40E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156988
PNG
(3-Cyclohexyl-1-[1-(3,3-diphenyl-propyl)-piperidin-...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)NC1CCCCC1
Show InChI InChI=1S/C28H39N3O/c1-30(28(32)29-25-15-9-4-10-16-25)26-17-20-31(21-18-26)22-19-27(23-11-5-2-6-12-23)24-13-7-3-8-14-24/h2-3,5-8,11-14,25-27H,4,9-10,15-22H2,1H3,(H,29,32)
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n/an/a 1.80E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157024
PNG
(CHEMBL182557 | N-[1-(3,3-Diphenyl-propyl)-piperidi...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1ccccc1F
Show InChI InChI=1S/C29H33FN2O/c1-31(29(33)22-25-14-8-9-15-28(25)30)26-16-19-32(20-17-26)21-18-27(23-10-4-2-5-11-23)24-12-6-3-7-13-24/h2-15,26-27H,16-22H2,1H3
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n/an/a 1.90E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156990
PNG
(1-Allyl-1-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]...)
Show SMILES C=CCN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Nc1ccccc1
Show InChI InChI=1S/C30H35N3O/c1-2-21-33(30(34)31-27-16-10-5-11-17-27)28-18-22-32(23-19-28)24-20-29(25-12-6-3-7-13-25)26-14-8-4-9-15-26/h2-17,28-29H,1,18-24H2,(H,31,34)
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n/an/a 2.10E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157005
PNG
(2-(3-Chloro-phenyl)-N-[1-(3,3-diphenyl-propyl)-pip...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1cccc(Cl)c1
Show InChI InChI=1S/C29H33ClN2O/c1-31(29(33)22-23-9-8-14-26(30)21-23)27-15-18-32(19-16-27)20-17-28(24-10-4-2-5-11-24)25-12-6-3-7-13-25/h2-14,21,27-28H,15-20,22H2,1H3
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n/an/a 2.20E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156971
PNG
(2-Biphenyl-4-yl-N-[1-(3,3-diphenyl-propyl)-piperid...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C35H38N2O/c1-36(35(38)27-28-17-19-30(20-18-28)29-11-5-2-6-12-29)33-21-24-37(25-22-33)26-23-34(31-13-7-3-8-14-31)32-15-9-4-10-16-32/h2-20,33-34H,21-27H2,1H3
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n/an/a 2.30E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156973
PNG
(2-(2,4-Dichloro-phenyl)-N-[1-(3,3-diphenyl-propyl)...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1ccc(Cl)cc1Cl
Show InChI InChI=1S/C29H32Cl2N2O/c1-32(29(34)20-24-12-13-25(30)21-28(24)31)26-14-17-33(18-15-26)19-16-27(22-8-4-2-5-9-22)23-10-6-3-7-11-23/h2-13,21,26-27H,14-20H2,1H3
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n/an/a 2.60E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156976
PNG
(2-(3,5-Dimethoxy-phenyl)-N-[1-(3,3-diphenyl-propyl...)
Show SMILES COc1cc(CC(=O)N(C)C2CCN(CCC(c3ccccc3)c3ccccc3)CC2)cc(OC)c1
Show InChI InChI=1S/C31H38N2O3/c1-32(31(34)22-24-20-28(35-2)23-29(21-24)36-3)27-14-17-33(18-15-27)19-16-30(25-10-6-4-7-11-25)26-12-8-5-9-13-26/h4-13,20-21,23,27,30H,14-19,22H2,1-3H3
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n/an/a 2.70E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157029
PNG
(CHEMBL182234 | N-[1-(3,3-Diphenyl-propyl)-piperidi...)
Show SMILES CC(C)CC(=O)N(C)C1CCN(CCC(c2ccccc2)c2ccccc2)CC1
Show InChI InChI=1S/C26H36N2O/c1-21(2)20-26(29)27(3)24-14-17-28(18-15-24)19-16-25(22-10-6-4-7-11-22)23-12-8-5-9-13-23/h4-13,21,24-25H,14-20H2,1-3H3
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n/an/a 3.40E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156996
PNG
(2-(4-Benzyloxy-phenyl)-N-[1-(3,3-diphenyl-propyl)-...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C36H40N2O2/c1-37(36(39)27-29-17-19-34(20-18-29)40-28-30-11-5-2-6-12-30)33-21-24-38(25-22-33)26-23-35(31-13-7-3-8-14-31)32-15-9-4-10-16-32/h2-20,33,35H,21-28H2,1H3
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n/an/a 3.50E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156994
PNG
(2-(2-Chloro-phenyl)-N-[1-(3,3-diphenyl-propyl)-pip...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Cc1ccccc1Cl
Show InChI InChI=1S/C29H33ClN2O/c1-31(29(33)22-25-14-8-9-15-28(25)30)26-16-19-32(20-17-26)21-18-27(23-10-4-2-5-11-23)24-12-6-3-7-13-24/h2-15,26-27H,16-22H2,1H3
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n/an/a 3.60E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157017
PNG
(1-Oxo-1,3-dihydro-isoindole-2-carboxylic acid [1-(...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)N1Cc2ccccc2C1=O
Show InChI InChI=1S/C30H33N3O2/c1-31(30(35)33-22-25-14-8-9-15-28(25)29(33)34)26-16-19-32(20-17-26)21-18-27(23-10-4-2-5-11-23)24-12-6-3-7-13-24/h2-15,26-27H,16-22H2,1H3
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n/an/a 4.10E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156968
PNG
(3-(3-Cyano-phenyl)-1-[1-(3,3-diphenyl-propyl)-pipe...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Nc1cccc(c1)C#N
Show InChI InChI=1S/C29H32N4O/c1-32(29(34)31-26-14-8-9-23(21-26)22-30)27-15-18-33(19-16-27)20-17-28(24-10-4-2-5-11-24)25-12-6-3-7-13-25/h2-14,21,27-28H,15-20H2,1H3,(H,31,34)
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n/an/a 4.90E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157020
PNG
(CHEMBL361414 | N-[1-(3,3-Diphenyl-propyl)-piperidi...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)c1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C28H31N3O3/c1-29(28(32)24-13-8-14-26(21-24)31(33)34)25-15-18-30(19-16-25)20-17-27(22-9-4-2-5-10-22)23-11-6-3-7-12-23/h2-14,21,25,27H,15-20H2,1H3
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n/an/a 5.10E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156985
PNG
(1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-1-ethyl...)
Show SMILES CCN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)NC(C)c1ccccc1
Show InChI InChI=1S/C31H39N3O/c1-3-34(31(35)32-25(2)26-13-7-4-8-14-26)29-19-22-33(23-20-29)24-21-30(27-15-9-5-10-16-27)28-17-11-6-12-18-28/h4-18,25,29-30H,3,19-24H2,1-2H3,(H,32,35)
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n/an/a 5.40E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156991
PNG
(CHEMBL427137 | N-[1-(3,3-Diphenyl-propyl)-piperidi...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)CC(C)(C)C
Show InChI InChI=1S/C27H38N2O/c1-27(2,3)21-26(30)28(4)24-15-18-29(19-16-24)20-17-25(22-11-7-5-8-12-22)23-13-9-6-10-14-23/h5-14,24-25H,15-21H2,1-4H3
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n/an/a 5.50E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157031
PNG
(1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-1-methy...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)Nc1cccc(C)c1
Show InChI InChI=1S/C29H35N3O/c1-23-10-9-15-26(22-23)30-29(33)31(2)27-16-19-32(20-17-27)21-18-28(24-11-5-3-6-12-24)25-13-7-4-8-14-25/h3-15,22,27-28H,16-21H2,1-2H3,(H,30,33)
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n/an/a 5.90E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157006
PNG
(CHEMBL182403 | N-[1-(3,3-Diphenyl-propyl)-piperidi...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)C(=O)c1ccccc1
Show InChI InChI=1S/C29H32N2O2/c1-30(29(33)28(32)25-15-9-4-10-16-25)26-17-20-31(21-18-26)22-19-27(23-11-5-2-6-12-23)24-13-7-3-8-14-24/h2-16,26-27H,17-22H2,1H3
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n/an/a 5.90E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157022
PNG
(CHEMBL182266 | N-[1-(3,3-Diphenyl-propyl)-piperidi...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)c1ccncc1
Show InChI InChI=1S/C27H31N3O/c1-29(27(31)24-12-17-28-18-13-24)25-14-19-30(20-15-25)21-16-26(22-8-4-2-5-9-22)23-10-6-3-7-11-23/h2-13,17-18,25-26H,14-16,19-21H2,1H3
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n/an/a 6.10E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156979
PNG
(CHEMBL362168 | N-[1-(3,3-Diphenyl-propyl)-piperidi...)
Show SMILES CC(C(=O)N(C)C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)c1ccccc1
Show InChI InChI=1S/C30H36N2O/c1-24(25-12-6-3-7-13-25)30(33)31(2)28-18-21-32(22-19-28)23-20-29(26-14-8-4-9-15-26)27-16-10-5-11-17-27/h3-17,24,28-29H,18-23H2,1-2H3
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n/an/a 6.80E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157001
PNG
(CHEMBL183907 | N-[1-(3,3-Diphenyl-propyl)-piperidi...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)c1ccc(F)cc1
Show InChI InChI=1S/C28H31FN2O/c1-30(28(32)24-12-14-25(29)15-13-24)26-16-19-31(20-17-26)21-18-27(22-8-4-2-5-9-22)23-10-6-3-7-11-23/h2-15,26-27H,16-21H2,1H3
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n/an/a 7.20E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50157011
PNG
(CHEMBL181502 | Cyclobutanecarboxylic acid [1-(3,3-...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)C1CCC1
Show InChI InChI=1S/C26H34N2O/c1-27(26(29)23-13-8-14-23)24-15-18-28(19-16-24)20-17-25(21-9-4-2-5-10-21)22-11-6-3-7-12-22/h2-7,9-12,23-25H,8,13-20H2,1H3
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n/an/a 7.40E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156997
PNG
(CHEMBL362388 | Furan-2-carboxylic acid [1-(3,3-dip...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)c1ccco1
Show InChI InChI=1S/C26H30N2O2/c1-27(26(29)25-13-8-20-30-25)23-14-17-28(18-15-23)19-16-24(21-9-4-2-5-10-21)22-11-6-3-7-12-22/h2-13,20,23-24H,14-19H2,1H3
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n/an/a 7.90E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50156993
PNG
(CHEMBL181260 | Thiophene-2-carboxylic acid [1-(3,3...)
Show SMILES CN(C1CCN(CCC(c2ccccc2)c2ccccc2)CC1)C(=O)c1cccs1
Show InChI InChI=1S/C26H30N2OS/c1-27(26(29)25-13-8-20-30-25)23-14-17-28(18-15-23)19-16-24(21-9-4-2-5-10-21)22-11-6-3-7-12-22/h2-13,20,23-24H,14-19H2,1H3
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n/an/a 8.70E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...

Bioorg Med Chem Lett 15: 25-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.044
BindingDB Entry DOI: 10.7270/Q2833RJJ
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%