Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50159366 ((2S,4R)-4-Acetylsulfanyl-2-(2,4,5-trifluoro-benzyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.90 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against human ECE-1 by RIA | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50159365 ((3R,5S)-5-{[(2,5-difluorobenzyl)amino]methyl}-1-(5...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 10.4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against human ECE-1 by RIA | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50098118 ((2S,4R)-4-Mercapto-2-(2,4,5-trifluoro-benzyloxymet...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against human ECE-1 by RIA | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50159364 (CHEMBL192441 | isopropyl (2S,4R)-2-{[(2,5-difluoro...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against human ECE-1 by RIA | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50159367 ((2S,4R)-4-Benzoylsulfanyl-2-(2,4,5-trifluoro-benzy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 49.7 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against human ECE-1 by RIA | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50159368 ((4R)-N'-methyl-N'-[(4-methylbenzene)sulfonyl]-1-(n...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 61.3 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against human ECE-1 by RIA | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50098118 ((2S,4R)-4-Mercapto-2-(2,4,5-trifluoro-benzyloxymet...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 67 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against human ECE-1 expressed in MDCK cells | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50159365 ((3R,5S)-5-{[(2,5-difluorobenzyl)amino]methyl}-1-(5...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 72.9 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against human ECE-1 expressed in MDCK cells | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50159366 ((2S,4R)-4-Acetylsulfanyl-2-(2,4,5-trifluoro-benzyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 76.5 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against human ECE-1 expressed in MDCK cells | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50159363 (CHEMBL177000 | methyl 2-(2-{N-methyl-1-[(4R)-1-(na...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 80.8 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against human ECE-1 by RIA | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50159367 ((2S,4R)-4-Benzoylsulfanyl-2-(2,4,5-trifluoro-benzy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 481 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against human ECE-1 expressed in MDCK cells | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50251742 ((3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against human ECE-1 by RIA | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50159364 (CHEMBL192441 | isopropyl (2S,4R)-2-{[(2,5-difluoro...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against human ECE-1 expressed in MDCK cells | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50159368 ((4R)-N'-methyl-N'-[(4-methylbenzene)sulfonyl]-1-(n...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.53E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against human ECE-1 expressed in MDCK cells | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50159363 (CHEMBL177000 | methyl 2-(2-{N-methyl-1-[(4R)-1-(na...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.09E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against human ECE-1 expressed in MDCK cells | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin-converting enzyme (Homo sapiens (Human)) | BDBM50098118 ((2S,4R)-4-Mercapto-2-(2,4,5-trifluoro-benzyloxymet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against human angiotensin I converting enzyme | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin-converting enzyme (Homo sapiens (Human)) | BDBM50159368 ((4R)-N'-methyl-N'-[(4-methylbenzene)sulfonyl]-1-(n...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against human angiotensin I converting enzyme | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-converting enzyme 1 (Homo sapiens (Human)) | BDBM50159369 (CGS-31,4447 | CHEMBL415967 | {1-[(S)-2-Biphenyl-4-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against human ECE-1 by RIA | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin-converting enzyme (Homo sapiens (Human)) | BDBM50159365 ((3R,5S)-5-{[(2,5-difluorobenzyl)amino]methyl}-1-(5...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against human angiotensin I converting enzyme | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin-converting enzyme (Homo sapiens (Human)) | BDBM50159363 (CHEMBL177000 | methyl 2-(2-{N-methyl-1-[(4R)-1-(na...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.66E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against human angiotensin I converting enzyme | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Homo sapiens (Human)) | BDBM50159368 ((4R)-N'-methyl-N'-[(4-methylbenzene)sulfonyl]-1-(n...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.92E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against Neprilysin | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Homo sapiens (Human)) | BDBM50159363 (CHEMBL177000 | methyl 2-(2-{N-methyl-1-[(4R)-1-(na...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.19E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against Neprilysin | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin-converting enzyme (Homo sapiens (Human)) | BDBM50159366 ((2S,4R)-4-Acetylsulfanyl-2-(2,4,5-trifluoro-benzyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against human angiotensin I converting enzyme | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin-converting enzyme (Homo sapiens (Human)) | BDBM50159364 (CHEMBL192441 | isopropyl (2S,4R)-2-{[(2,5-difluoro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against human angiotensin I converting enzyme | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Homo sapiens (Human)) | BDBM50159366 ((2S,4R)-4-Acetylsulfanyl-2-(2,4,5-trifluoro-benzyl...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against Neprilysin | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Homo sapiens (Human)) | BDBM50159365 ((3R,5S)-5-{[(2,5-difluorobenzyl)amino]methyl}-1-(5...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against Neprilysin | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Homo sapiens (Human)) | BDBM50159364 (CHEMBL192441 | isopropyl (2S,4R)-2-{[(2,5-difluoro...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against Neprilysin | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Homo sapiens (Human)) | BDBM50098118 ((2S,4R)-4-Mercapto-2-(2,4,5-trifluoro-benzyloxymet...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against Neprilysin | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin-converting enzyme (Homo sapiens (Human)) | BDBM50159367 ((2S,4R)-4-Benzoylsulfanyl-2-(2,4,5-trifluoro-benzy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against human angiotensin I converting enzyme | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Homo sapiens (Human)) | BDBM50159367 ((2S,4R)-4-Benzoylsulfanyl-2-(2,4,5-trifluoro-benzy...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pathology Curated by ChEMBL | Assay Description Inhibitory concentration against Neprilysin | J Med Chem 48: 483-98 (2005) Article DOI: 10.1021/jm040857x BindingDB Entry DOI: 10.7270/Q2VM4D1H | |||||||||||
More data for this Ligand-Target Pair |