Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-L/Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50161080 ((S)-2-[(S)-3-Isobutyl-2,5-dioxo-4-((E)-3-pyridin-4...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1) | Bioorg Med Chem Lett 15: 1217-20 (2005) Article DOI: 10.1016/j.bmcl.2004.11.072 BindingDB Entry DOI: 10.7270/Q20Z72S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50161067 ((2R)-2-[3-ISOBUTYL-2,5-DIOXO-4-(QUINOLIN-3-YLMETHY...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1) | Bioorg Med Chem Lett 15: 1217-20 (2005) Article DOI: 10.1016/j.bmcl.2004.11.072 BindingDB Entry DOI: 10.7270/Q20Z72S2 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Integrin alpha-L/Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50123241 ((S)-2-[(3S,5R)-3-Isobutyl-5-methyl-2-oxo-4-(2-quin...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1) | Bioorg Med Chem Lett 15: 1217-20 (2005) Article DOI: 10.1016/j.bmcl.2004.11.072 BindingDB Entry DOI: 10.7270/Q20Z72S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50161072 ((S)-2-((S)-3-Isobutyl-2,5-dioxo-4-quinolin-6-yl-[1...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1) | Bioorg Med Chem Lett 15: 1217-20 (2005) Article DOI: 10.1016/j.bmcl.2004.11.072 BindingDB Entry DOI: 10.7270/Q20Z72S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50161065 ((S)-2-((R)-3-Isobutyl-2,5-dioxo-4-quinolin-3-ylmet...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1) | Bioorg Med Chem Lett 15: 1217-20 (2005) Article DOI: 10.1016/j.bmcl.2004.11.072 BindingDB Entry DOI: 10.7270/Q20Z72S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50161071 ((S)-2-[(S)-4-(4-Dimethylamino-benzyl)-3-isobutyl-2...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1) | Bioorg Med Chem Lett 15: 1217-20 (2005) Article DOI: 10.1016/j.bmcl.2004.11.072 BindingDB Entry DOI: 10.7270/Q20Z72S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50161076 ((S)-2-[(S)-3-Isobutyl-4-(3-methyl-quinolin-5-ylmet...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 890 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1) | Bioorg Med Chem Lett 15: 1217-20 (2005) Article DOI: 10.1016/j.bmcl.2004.11.072 BindingDB Entry DOI: 10.7270/Q20Z72S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50161082 ((S)-2-[(S)-4-(4-Hydroxy-3-methoxy-benzyl)-3-isobut...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 950 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1) | Bioorg Med Chem Lett 15: 1217-20 (2005) Article DOI: 10.1016/j.bmcl.2004.11.072 BindingDB Entry DOI: 10.7270/Q20Z72S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50161078 ((S)-2-[(S)-4-(3-Hydroxy-benzyl)-3-isobutyl-2,5-dio...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1) | Bioorg Med Chem Lett 15: 1217-20 (2005) Article DOI: 10.1016/j.bmcl.2004.11.072 BindingDB Entry DOI: 10.7270/Q20Z72S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50161068 ((S)-2-((S)-4-Benzyl-3-isobutyl-2,5-dioxo-[1,4]diaz...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1) | Bioorg Med Chem Lett 15: 1217-20 (2005) Article DOI: 10.1016/j.bmcl.2004.11.072 BindingDB Entry DOI: 10.7270/Q20Z72S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50161069 ((S)-2-[(S)-4-(4-Bromo-benzyl)-3-isobutyl-2,5-dioxo...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1) | Bioorg Med Chem Lett 15: 1217-20 (2005) Article DOI: 10.1016/j.bmcl.2004.11.072 BindingDB Entry DOI: 10.7270/Q20Z72S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50161075 ((S)-2-[(S)-4-(4-Bromo-cyclohexa-1,3-dienylmethyl)-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1) | Bioorg Med Chem Lett 15: 1217-20 (2005) Article DOI: 10.1016/j.bmcl.2004.11.072 BindingDB Entry DOI: 10.7270/Q20Z72S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50161073 ((S)-2-[(S)-3-Isobutyl-2,5-dioxo-4-(pyridin-4-ylcar...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1) | Bioorg Med Chem Lett 15: 1217-20 (2005) Article DOI: 10.1016/j.bmcl.2004.11.072 BindingDB Entry DOI: 10.7270/Q20Z72S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50161070 ((R)-2-((R)-3-Isobutyl-2,5-dioxo-4-quinolin-3-ylmet...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1) | Bioorg Med Chem Lett 15: 1217-20 (2005) Article DOI: 10.1016/j.bmcl.2004.11.072 BindingDB Entry DOI: 10.7270/Q20Z72S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50161074 ((R)-2-((S)-3-Isobutyl-2,5-dioxo-4-quinolin-3-ylmet...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1) | Bioorg Med Chem Lett 15: 1217-20 (2005) Article DOI: 10.1016/j.bmcl.2004.11.072 BindingDB Entry DOI: 10.7270/Q20Z72S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50161077 ((S)-2-[(S)-4-(3-Benzyloxy-benzyl)-3-isobutyl-2,5-d...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1) | Bioorg Med Chem Lett 15: 1217-20 (2005) Article DOI: 10.1016/j.bmcl.2004.11.072 BindingDB Entry DOI: 10.7270/Q20Z72S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50161066 ((S)-2-[(S)-3-Isobutyl-2,5-dioxo-4-(4-pyridin-3-yl-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.33E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1) | Bioorg Med Chem Lett 15: 1217-20 (2005) Article DOI: 10.1016/j.bmcl.2004.11.072 BindingDB Entry DOI: 10.7270/Q20Z72S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50161079 ((S)-2-((S)-3-Isobutyl-2,5-dioxo-4-quinolin-6-ylmet...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.44E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1) | Bioorg Med Chem Lett 15: 1217-20 (2005) Article DOI: 10.1016/j.bmcl.2004.11.072 BindingDB Entry DOI: 10.7270/Q20Z72S2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/Intercellular adhesion molecule 1 (Homo sapiens (Human)) | BDBM50161081 ((S)-2-((S)-3-Isobutyl-2,5-dioxo-4-pyridin-4-ylmeth...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description In vitro inhibitory concentrationfor Lymphocyte function associated antigen 1/Intercellular adhesion molecule 1 (LFA-1/ICAM-1) | Bioorg Med Chem Lett 15: 1217-20 (2005) Article DOI: 10.1016/j.bmcl.2004.11.072 BindingDB Entry DOI: 10.7270/Q20Z72S2 | |||||||||||
More data for this Ligand-Target Pair |