Affinity Data by PubMed id=15713415

PubMed code 15713415

Found 13 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50161662 ((S)-3-(4-{(Z)-2-[4-((R)-2-Carboxy-2-ethoxy-ethyl)-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Effective concentration for human peroxisome proliferator-activated receptor gamma				Bioorg Med Chem Lett 15: 1497-500 (2005) Article DOI: 10.1016/j.bmcl.2004.12.084 BindingDB Entry DOI: 10.7270/Q2NK3DK3
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50161665 (5-[(3aS,4R,6S,6aS)-4-Hydroxy-6-((E)-(S)-4-hydroxy-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Effective concentration for human peroxisome proliferator-activated receptor gamma				Bioorg Med Chem Lett 15: 1497-500 (2005) Article DOI: 10.1016/j.bmcl.2004.12.084 BindingDB Entry DOI: 10.7270/Q2NK3DK3
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM24566 (2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidi...) Show SMILES Cc1cccc(Nc2cc(Cl)nc(SCC(O)=O)n2)c1C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Effective concentration for human peroxisome proliferator-activated receptor alpha				Bioorg Med Chem Lett 15: 1497-500 (2005) Article DOI: 10.1016/j.bmcl.2004.12.084 BindingDB Entry DOI: 10.7270/Q2NK3DK3
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28681 (5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Effective concentration for human peroxisome proliferator-activated receptor alpha				Bioorg Med Chem Lett 15: 1497-500 (2005) Article DOI: 10.1016/j.bmcl.2004.12.084 BindingDB Entry DOI: 10.7270/Q2NK3DK3
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50161665 (5-[(3aS,4R,6S,6aS)-4-Hydroxy-6-((E)-(S)-4-hydroxy-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Effective concentration for human peroxisome proliferator-activated receptor alpha				Bioorg Med Chem Lett 15: 1497-500 (2005) Article DOI: 10.1016/j.bmcl.2004.12.084 BindingDB Entry DOI: 10.7270/Q2NK3DK3
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50161665 (5-[(3aS,4R,6S,6aS)-4-Hydroxy-6-((E)-(S)-4-hydroxy-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Effective concentration for human peroxisome proliferator-activated receptor delta				Bioorg Med Chem Lett 15: 1497-500 (2005) Article DOI: 10.1016/j.bmcl.2004.12.084 BindingDB Entry DOI: 10.7270/Q2NK3DK3
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50161660 ((S)-3-(4-{4-[4-((S)-2-Carboxy-2-ethoxy-ethyl)-phen...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Effective concentration for human peroxisome proliferator-activated receptor gamma				Bioorg Med Chem Lett 15: 1497-500 (2005) Article DOI: 10.1016/j.bmcl.2004.12.084 BindingDB Entry DOI: 10.7270/Q2NK3DK3
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50161664 ((S)-2-Ethoxy-3-[4-((Z)-3-methyl-5-phenyl-pent-2-en...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Effective concentration for human peroxisome proliferator-activated receptor gamma				Bioorg Med Chem Lett 15: 1497-500 (2005) Article DOI: 10.1016/j.bmcl.2004.12.084 BindingDB Entry DOI: 10.7270/Q2NK3DK3
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50161664 ((S)-2-Ethoxy-3-[4-((Z)-3-methyl-5-phenyl-pent-2-en...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Effective concentration for human peroxisome proliferator-activated receptor alpha				Bioorg Med Chem Lett 15: 1497-500 (2005) Article DOI: 10.1016/j.bmcl.2004.12.084 BindingDB Entry DOI: 10.7270/Q2NK3DK3
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50161664 ((S)-2-Ethoxy-3-[4-((Z)-3-methyl-5-phenyl-pent-2-en...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Effective concentration for human peroxisome proliferator-activated receptor delta				Bioorg Med Chem Lett 15: 1497-500 (2005) Article DOI: 10.1016/j.bmcl.2004.12.084 BindingDB Entry DOI: 10.7270/Q2NK3DK3
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28681 (5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Effective concentration for human peroxisome proliferator-activated receptor gamma				Bioorg Med Chem Lett 15: 1497-500 (2005) Article DOI: 10.1016/j.bmcl.2004.12.084 BindingDB Entry DOI: 10.7270/Q2NK3DK3
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50161660 ((S)-3-(4-{4-[4-((S)-2-Carboxy-2-ethoxy-ethyl)-phen...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Effective concentration for human peroxisome proliferator-activated receptor alpha				Bioorg Med Chem Lett 15: 1497-500 (2005) Article DOI: 10.1016/j.bmcl.2004.12.084 BindingDB Entry DOI: 10.7270/Q2NK3DK3
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM24566 (2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidi...) Show SMILES Cc1cccc(Nc2cc(Cl)nc(SCC(O)=O)n2)c1C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Effective concentration for human peroxisome proliferator-activated receptor gamma				Bioorg Med Chem Lett 15: 1497-500 (2005) Article DOI: 10.1016/j.bmcl.2004.12.084 BindingDB Entry DOI: 10.7270/Q2NK3DK3
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%