Affinity Data by PubMed id=1573639

PubMed code 1573639

Found 17 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50005795 (2,8-Diamino-9-thiophen-2-ylmethyl-1,9-dihydro-puri...) Show SMILES Nc1nc2c(nc(N)[nH]c2=O)n1Cc1cccs1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory activity against Purine nucleoside phosphorylase evaluated by radiochemical assay				J Med Chem 35: 1451-7 (1992) BindingDB Entry DOI: 10.7270/Q2MW2HSF
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50005802 (2,8-Diamino-9-furan-2-ylmethyl-1,9-dihydro-purin-6...) Show SMILES Nc1nc2c(nc(N)[nH]c2=O)n1Cc1ccco1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory activity against Purine nucleoside phosphorylase evaluated by radiochemical assay				J Med Chem 35: 1451-7 (1992) BindingDB Entry DOI: 10.7270/Q2MW2HSF
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50005799 (2,8-Diamino-9-benzyl-1,9-dihydro-purin-6-one \| CHE...) Show SMILES Nc1nc2c(nc(N)[nH]c2=O)n1Cc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory activity against Purine nucleoside phosphorylase evaluated by radiochemical assay				J Med Chem 35: 1451-7 (1992) BindingDB Entry DOI: 10.7270/Q2MW2HSF
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50404028 (CHEMBL2021376) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory activity against Purine nucleoside phosphorylase evaluated by radiochemical assay				J Med Chem 35: 1451-7 (1992) BindingDB Entry DOI: 10.7270/Q2MW2HSF
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50005793 (2,8-Diamino-3-thiophen-2-ylmethyl-1,9-dihydro-puri...) Show SMILES Nc1nc2c(O)nc(N)n(Cc3cccs3)c2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory activity against Purine nucleoside phosphorylase evaluated by radiochemical assay				J Med Chem 35: 1451-7 (1992) BindingDB Entry DOI: 10.7270/Q2MW2HSF
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50005798 (2,8-Diamino-3-benzyl-1,9-dihydro-purin-6-one \| CHE...) Show SMILES Nc1nc2c(O)nc(N)n(Cc3ccccc3)c2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory activity against Purine nucleoside phosphorylase evaluated by radiochemical assay				J Med Chem 35: 1451-7 (1992) BindingDB Entry DOI: 10.7270/Q2MW2HSF
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50005806 (2,8-Diamino-3-furan-2-ylmethyl-1,9-dihydro-purin-6...) Show SMILES Nc1nc2c(O)nc(N)n(Cc3ccco3)c2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory activity against Purine nucleoside phosphorylase evaluated by radiochemical assay				J Med Chem 35: 1451-7 (1992) BindingDB Entry DOI: 10.7270/Q2MW2HSF
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50005804 (2,8-Diamino-3-(4-methoxy-benzyl)-1,9-dihydro-purin...) Show SMILES COc1ccc(Cn2c(N)nc(O)c3nc(N)nc23)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory activity against Purine nucleoside phosphorylase evaluated by radiochemical assay				J Med Chem 35: 1451-7 (1992) BindingDB Entry DOI: 10.7270/Q2MW2HSF
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50005800 (2-Amino-3-benzyl-1,9-dihydro-purin-6-one \| CHEMBL3...) Show SMILES Nc1nc(O)c2ncnc2n1Cc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory activity against Purine nucleoside phosphorylase evaluated by radiochemical assay				J Med Chem 35: 1451-7 (1992) BindingDB Entry DOI: 10.7270/Q2MW2HSF
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50005801 (3-Benzyl-2-hydroxy-1,9-dihydro-purin-6-one \| CHEMB...) Show SMILES O=c1[nH]c(=O)c2[nH]cnc2n1Cc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.34E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory activity against Purine nucleoside phosphorylase evaluated by radiochemical assay				J Med Chem 35: 1451-7 (1992) BindingDB Entry DOI: 10.7270/Q2MW2HSF
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50005796 (2-Amino-9-benzyl-1,9-dihydro-purin-6-one \| CHEMBL3...) Show SMILES Nc1nc2n(Cc3ccccc3)cnc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory activity against Purine nucleoside phosphorylase evaluated by radiochemical assay				J Med Chem 35: 1451-7 (1992) BindingDB Entry DOI: 10.7270/Q2MW2HSF
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50005803 (8-Amino-3-benzyl-1,9-dihydro-purin-6-one \| CHEMBL3...) Show SMILES Nc1nc2c(O)ncn(Cc3ccccc3)c2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory activity against Purine nucleoside phosphorylase evaluated by radiochemical assay				J Med Chem 35: 1451-7 (1992) BindingDB Entry DOI: 10.7270/Q2MW2HSF
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50005805 (8-Amino-3-benzyl-2-methylsulfanyl-1,9-dihydro-puri...) Show SMILES CSc1nc(O)c2nc(N)nc2n1Cc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory activity against Purine nucleoside phosphorylase evaluated by radiochemical assay				J Med Chem 35: 1451-7 (1992) BindingDB Entry DOI: 10.7270/Q2MW2HSF
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50005797 (6-Amino-3-benzyl-9H-purin-3-ium; chloride \| CHEMBL...) Show SMILES Nc1[nH+]cn(Cc2ccccc2)c2ncnc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory activity against Purine nucleoside phosphorylase evaluated by radiochemical assay				J Med Chem 35: 1451-7 (1992) BindingDB Entry DOI: 10.7270/Q2MW2HSF
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50005794 (3-Benzyl-1,9-dihydro-purin-6-one \| 3-Benzyl-3,7-di...) Show SMILES Oc1ncn(Cc2ccccc2)c2ncnc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.12E+5	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory activity against Purine nucleoside phosphorylase evaluated by radiochemical assay				J Med Chem 35: 1451-7 (1992) BindingDB Entry DOI: 10.7270/Q2MW2HSF
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50005791 (8-Amino-3-benzyl-1,9-dihydro-purine-6-thione \| CHE...) Show SMILES Nc1nc2c(S)ncn(Cc3ccccc3)c2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.31E+5	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory activity against Purine nucleoside phosphorylase evaluated by radiochemical assay				J Med Chem 35: 1451-7 (1992) BindingDB Entry DOI: 10.7270/Q2MW2HSF
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50005807 (CHEMBL35798 \| N-(2-Amino-3-benzyl-6-oxo-6,9-dihydr...) Show SMILES Nc1nc(O)c2nc(NC=O)nc2n1Cc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory activity against Purine nucleoside phosphorylase evaluated by radiochemical assay				J Med Chem 35: 1451-7 (1992) BindingDB Entry DOI: 10.7270/Q2MW2HSF
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%