Affinity Data by PubMed id=15743177

PubMed code 15743177

Found 43 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50083534 (1-Methyl-4-naphthalen-2-yl-piperidine-4-carboxylic...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc2ccccc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]paroxetine binding to rat serotonin transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50083536 (4-(3,4-Dichloro-phenyl)-1-methyl-piperidine-4-carb...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(Cl)c(Cl)c1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]paroxetine binding to rat serotonin transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50083530 (4-(4-Iodo-phenyl)-1-methyl-piperidine-4-carboxylic...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(I)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]paroxetine binding to rat serotonin transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50083536 (4-(3,4-Dichloro-phenyl)-1-methyl-piperidine-4-carb...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(Cl)c(Cl)c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	125	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to rat dopamine transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50083528 (1-Methyl-4-naphthalen-2-yl-piperidine-4-carbonitri...) Show SMILES CN1CCC(CC1)(C#N)c1ccc2ccccc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	125	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]paroxetine binding to rat serotonin transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50083532 (4-(4-Chloro-phenyl)-1-methyl-piperidine-4-carboxyl...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(Cl)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	277	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]paroxetine binding to rat serotonin transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50083529 (4-(4-Fluoro-phenyl)-1-methyl-piperidine-4-carboxyl...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(F)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	308	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]paroxetine binding to rat serotonin transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50026752 (1-Methyl-4-phenyl-piperidine-4-carboxylic acid eth...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	413	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]paroxetine binding to rat serotonin transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50083531 (4-(4-Iodo-phenyl)-1-methyl-piperidine-4-carbonitri...) Show SMILES CN1CCC(CC1)(C#N)c1ccc(I)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]paroxetine binding to rat serotonin transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50083526 (4-(3,4-Dichloro-phenyl)-1-methyl-piperidine-4-carb...) Show SMILES CN1CCC(CC1)(C#N)c1ccc(Cl)c(Cl)c1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	805	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]paroxetine binding to rat serotonin transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50026752 (1-Methyl-4-phenyl-piperidine-4-carboxylic acid eth...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccccc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	920	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]DAMGO binding to mu-opioid receptor				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50083534 (1-Methyl-4-naphthalen-2-yl-piperidine-4-carboxylic...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc2ccccc2c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to rat dopamine transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50083525 (1-Methyl-4-p-tolyl-piperidine-4-carboxylic acid et...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(C)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.61E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]paroxetine binding to rat serotonin transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50083534 (1-Methyl-4-naphthalen-2-yl-piperidine-4-carboxylic...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc2ccccc2c1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.03E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]DAMGO binding to mu-opioid receptor				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50083536 (4-(3,4-Dichloro-phenyl)-1-methyl-piperidine-4-carb...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(Cl)c(Cl)c1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.04E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]DAMGO binding to mu-opioid receptor				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50083530 (4-(4-Iodo-phenyl)-1-methyl-piperidine-4-carboxylic...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(I)cc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.35E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]DAMGO binding to mu-opioid receptor				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50083528 (1-Methyl-4-naphthalen-2-yl-piperidine-4-carbonitri...) Show SMILES CN1CCC(CC1)(C#N)c1ccc2ccccc2c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.36E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to rat dopamine transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50083526 (4-(3,4-Dichloro-phenyl)-1-methyl-piperidine-4-carb...) Show SMILES CN1CCC(CC1)(C#N)c1ccc(Cl)c(Cl)c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.67E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to rat dopamine transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50083525 (1-Methyl-4-p-tolyl-piperidine-4-carboxylic acid et...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(C)cc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.67E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]DAMGO binding to mu-opioid receptor				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50083530 (4-(4-Iodo-phenyl)-1-methyl-piperidine-4-carboxylic...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(I)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to rat dopamine transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50083532 (4-(4-Chloro-phenyl)-1-methyl-piperidine-4-carboxyl...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(Cl)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to rat dopamine transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50083532 (4-(4-Chloro-phenyl)-1-methyl-piperidine-4-carboxyl...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(Cl)cc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.41E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]DAMGO binding to mu-opioid receptor				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50083533 (4-(4-Chloro-phenyl)-1-methyl-piperidine-4-carbonit...) Show SMILES CN1CCC(CC1)(C#N)c1ccc(Cl)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.11E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]paroxetine binding to rat serotonin transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50083531 (4-(4-Iodo-phenyl)-1-methyl-piperidine-4-carbonitri...) Show SMILES CN1CCC(CC1)(C#N)c1ccc(I)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.34E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to rat dopamine transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50083524 (4-(4-Fluoro-phenyl)-1-methyl-piperidine-4-carbonit...) Show SMILES CN1CCC(CC1)(C#N)c1ccc(F)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.01E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]paroxetine binding to rat serotonin transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50083529 (4-(4-Fluoro-phenyl)-1-methyl-piperidine-4-carboxyl...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(F)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.07E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to rat dopamine transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50083525 (1-Methyl-4-p-tolyl-piperidine-4-carboxylic acid et...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(C)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.24E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to rat dopamine transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50083527 (1-Methyl-4-p-tolyl-piperidine-4-carbonitrile \| CHE...) Show SMILES CN1CCC(CC1)(C#N)c1ccc(C)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.37E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]paroxetine binding to rat serotonin transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50083528 (1-Methyl-4-naphthalen-2-yl-piperidine-4-carbonitri...) Show SMILES CN1CCC(CC1)(C#N)c1ccc2ccccc2c1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.54E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]DAMGO binding to mu-opioid receptor at 100 uM				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50083531 (4-(4-Iodo-phenyl)-1-methyl-piperidine-4-carbonitri...) Show SMILES CN1CCC(CC1)(C#N)c1ccc(I)cc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.73E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]DAMGO binding to mu-opioid receptor at 100 uM				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50026752 (1-Methyl-4-phenyl-piperidine-4-carboxylic acid eth...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.78E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to rat dopamine transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50083533 (4-(4-Chloro-phenyl)-1-methyl-piperidine-4-carbonit...) Show SMILES CN1CCC(CC1)(C#N)c1ccc(Cl)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to rat dopamine transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50084717 ((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to rat dopamine transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50083533 (4-(4-Chloro-phenyl)-1-methyl-piperidine-4-carbonit...) Show SMILES CN1CCC(CC1)(C#N)c1ccc(Cl)cc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.68E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]DAMGO binding to mu-opioid receptor at 100 uM				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50083526 (4-(3,4-Dichloro-phenyl)-1-methyl-piperidine-4-carb...) Show SMILES CN1CCC(CC1)(C#N)c1ccc(Cl)c(Cl)c1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]DAMGO binding to mu-opioid receptor				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50083527 (1-Methyl-4-p-tolyl-piperidine-4-carbonitrile \| CHE...) Show SMILES CN1CCC(CC1)(C#N)c1ccc(C)cc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.06E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]DAMGO binding to mu-opioid receptor				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50083527 (1-Methyl-4-p-tolyl-piperidine-4-carbonitrile \| CHE...) Show SMILES CN1CCC(CC1)(C#N)c1ccc(C)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.18E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to rat dopamine transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50083534 (1-Methyl-4-naphthalen-2-yl-piperidine-4-carboxylic...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc2ccccc2c1 Show InChI	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.11E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]-nisoxetine binding to rat norepinephrine transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50083536 (4-(3,4-Dichloro-phenyl)-1-methyl-piperidine-4-carb...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(Cl)c(Cl)c1 Show InChI	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.45E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]-nisoxetine binding to rat norepinephrine transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50083524 (4-(4-Fluoro-phenyl)-1-methyl-piperidine-4-carbonit...) Show SMILES CN1CCC(CC1)(C#N)c1ccc(F)cc1 Show InChI	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.01E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine binding to rat norepinephrine transporter at 10 uM				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50084717 ((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.88E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to rat dopamine transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50083530 (4-(4-Iodo-phenyl)-1-methyl-piperidine-4-carboxylic...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(I)cc1 Show InChI	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.19E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]-nisoxetine binding to rat norepinephrine transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50083532 (4-(4-Chloro-phenyl)-1-methyl-piperidine-4-carboxyl...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(Cl)cc1 Show InChI	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.01E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]-nisoxetine binding to rat norepinephrine transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%