Affinity Data by PubMed id=15745796

PubMed code 15745796

Found 22 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50161093 ((R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthale...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
NPS Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162536 (6-Fluoro-3-[2-(3-fluoro-phenyl)-ethyl]-2-(2-hydrox...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
NPS Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162537 (6-Fluoro-2-(2-hydroxy-phenyl)-3-phenethyl-3H-quina...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
NPS Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162547 (3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
NPS Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162538 (2-(2-Hydroxy-phenyl)-5-methyl-3-phenethyl-3H-quina...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
NPS Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162554 (2-(2-Hydroxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...) Show SMILES Oc1ccccc1-c1nc2ccccc2c(=O)n1CCc1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
NPS Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162553 (6-Chloro-2-(2-hydroxy-phenyl)-3-phenethyl-3H-quina...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
NPS Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162539 (3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
NPS Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162552 (7-Fluoro-2-(2-hydroxy-phenyl)-3-phenethyl-3H-quina...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
NPS Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162545 (2-(2-Hydroxy-phenyl)-8-methyl-3-phenethyl-3H-quina...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
NPS Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162555 (3-[2-(3-Chloro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
NPS Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162546 (2-(2,5-Dihydroxy-phenyl)-3-phenethyl-3H-quinazolin...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
NPS Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162549 (7-Chloro-3-[2-(3-fluoro-phenyl)-ethyl]-2-(2-hydrox...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
NPS Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162535 (2-(3-Hydroxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
NPS Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162542 (2-Furan-2-yl-3-phenethyl-3H-quinazolin-4-one \| CHE...) Show SMILES O=c1n(CCc2ccccc2)c(nc2ccccc12)-c1ccco1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
NPS Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162540 (3-Phenethyl-2-phenyl-3H-quinazolin-4-one \| CHEMBL1...) Show SMILES O=c1n(CCc2ccccc2)c(nc2ccccc12)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
NPS Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162543 (2-(3-Fluoro-phenyl)-3-phenethyl-3H-quinazolin-4-on...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
NPS Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162544 (2-(2-Methoxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...) Show SMILES COc1ccccc1-c1nc2ccccc2c(=O)n1CCc1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
NPS Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162541 (2-(4-Hydroxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
NPS Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162548 (2-(4-Methoxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
NPS Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162550 (2-(3-Methoxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
NPS Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50162551 (2-(2-Fluoro-phenyl)-3-phenethyl-3H-quinazolin-4-on...) Show SMILES Fc1ccccc1-c1nc2ccccc2c(=O)n1CCc1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human calcium receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 15: 1557-60 (2005) Article DOI: 10.1016/j.bmcl.2005.01.078 BindingDB Entry DOI: 10.7270/Q22N51SD
NPS Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%