Affinity Data by PubMed id=15780613

PubMed code 15780613

Found 28 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cathepsin K (Homo sapiens (Human))	BDBM50163831 ((2S)-1-cyclohexylpropan-2-yl 1-cyanoazetidine-2-ca...) Show SMILES C[C@@H](CC1CCCCC1)OC(=O)C1CCN1C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0480	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin K using 10 uM Cbz-Phe-Arg-AMC				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50148310 (((S)-1-Formyl-pentyl)-carbamic acid (S)-1-benzyl-p...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin K using 10 uM Cbz-Phe-Arg-AMC				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Procathepsin L (Homo sapiens (Human))	BDBM50163831 ((2S)-1-cyclohexylpropan-2-yl 1-cyanoazetidine-2-ca...) Show SMILES C[C@@H](CC1CCCCC1)OC(=O)C1CCN1C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.710	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin L using 5 uM Cbz-Phe-Arg-AMC				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50163832 ((1S)-2-cyclohexyl-1-methylethyl (2S)-1-cyanopyrrol...) Show SMILES C[C@@H](CC1CCCCC1)OC(=O)C1CCCN1C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin K using 10 uM Cbz-Phe-Arg-AMC				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50163831 ((2S)-1-cyclohexylpropan-2-yl 1-cyanoazetidine-2-ca...) Show SMILES C[C@@H](CC1CCCCC1)OC(=O)C1CCN1C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin B using 10 uM Cbz-Phe-Arg-AMC				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50148291 (((S)-1-Formyl-pentyl)-carbamic acid (S)-2-cyclohex...) Show SMILES CCCC[C@H](NC(=O)O[C@@H](C)CC1CCCCC1)C=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin K using 10 uM Cbz-Phe-Arg-AMC				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50163841 ((1-Cyano-pyrrolidin-3-yl)-carbamic acid (S)-1-cycl...) Show SMILES CC[C@@H](CC1CCCCC1)OC(=O)NC1CCN(C1)C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin K using 10 uM Cbz-Phe-Arg-AMC				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50163838 ((1-Cyano-pyrrolidin-3-yl)-carbamic acid (S)-2-cycl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin K using 10 uM Cbz-Phe-Arg-AMC				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50163842 (CHEMBL183658 \| [1-((S)-1-Cyano-pyrrolidin-3-ylcarb...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin K using 10 uM Cbz-Phe-Arg-AMC				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Pro-cathepsin H (Homo sapiens (Human))	BDBM50163831 ((2S)-1-cyclohexylpropan-2-yl 1-cyanoazetidine-2-ca...) Show SMILES C[C@@H](CC1CCCCC1)OC(=O)C1CCN1C#N Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin H using 50 uM L-Arg-beta-naphthalamide				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50163836 (((R)-1-Formyl-pentyl)-carbamic acid tert-butyl est...) Show SMILES CCCC[C@@H](NC(=O)OC(C)(C)C)C=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin K using 10 uM Cbz-Phe-Arg-AMC				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50163834 ((S)-1-Cyano-pyrrolidine-2-carboxylic acid tert-but...) Show SMILES CC(C)(C)OC(=O)[C@@H]1CCCN1C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin K using 10 uM Cbz-Phe-Arg-AMC				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50163838 ((1-Cyano-pyrrolidin-3-yl)-carbamic acid (S)-2-cycl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin L using 5 uM Cbz-Phe-Arg-AMC				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50024322 (CHEMBL2096777) Show SMILES CC(C)(C)OC(=O)N[C@H]1CCN(C1)C#N \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin K using 10 uM Cbz-Phe-Arg-AMC				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50163832 ((1S)-2-cyclohexyl-1-methylethyl (2S)-1-cyanopyrrol...) Show SMILES C[C@@H](CC1CCCCC1)OC(=O)C1CCCN1C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin L using 5 uM Cbz-Phe-Arg-AMC				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50024323 (CHEMBL2096698) Show SMILES CC(C)(C)OC(=O)N[C@@H]1CCN(C1)C#N \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin K using 10 uM Cbz-Phe-Arg-AMC				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50163845 (3-Cyanoamino-pyrrolidine-1-carboxylic acid (S)-1-c...) Show SMILES CC[C@@H](CC1CCCCC1)OC(=O)N1CCC(C1)NC#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin K using 10 uM Cbz-Phe-Arg-AMC				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50163839 ((R)-1-Cyano-pyrrolidine-2-carboxylic acid tert-but...) Show SMILES CC(C)(C)OC(=O)[C@H]1CCCN1C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin K using 10 uM Cbz-Phe-Arg-AMC				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50163832 ((1S)-2-cyclohexyl-1-methylethyl (2S)-1-cyanopyrrol...) Show SMILES C[C@@H](CC1CCCCC1)OC(=O)C1CCCN1C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin B using 10 uM Cbz-Phe-Arg-AMC				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50163837 (2-Cyano-pyrazolidine-1-carboxylic acid tert-butyl ...) Show SMILES CC(C)(C)OC(=O)N1CCCN1C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin K using 10 uM Cbz-Phe-Arg-AMC				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50163844 ((3S,4R)-1-Cyano-4-(3-cyclopentyloxy-4-methoxy-phen...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin K using 10 uM Cbz-Phe-Arg-AMC				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Pro-cathepsin H (Homo sapiens (Human))	BDBM50163832 ((1S)-2-cyclohexyl-1-methylethyl (2S)-1-cyanopyrrol...) Show SMILES C[C@@H](CC1CCCCC1)OC(=O)C1CCCN1C#N Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin H using 50 uM L-Arg-beta-naphthalamide				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50163838 ((1-Cyano-pyrrolidin-3-yl)-carbamic acid (S)-2-cycl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin B using 10 uM Cbz-Phe-Arg-AMC				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50163843 ((R)-1-Cyano-pyrrolidine-2-carboxylic acid tert-but...) Show SMILES CN(C(=O)[C@H]1CCCN1C#N)C(C)(C)C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin K using 10 uM Cbz-Phe-Arg-AMC				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50163840 ((S)-1-Cyano-piperidine-2-carboxylic acid tert-buty...) Show SMILES CC(C)(C)OC(=O)[C@@H]1CCCCN1C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin K using 10 uM Cbz-Phe-Arg-AMC				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50095495 (CHEMBL262697 \| Pyrrolidine-1-carbonitrile) Show SMILES N#CN1CCCC1 Show InChI InChI=1S/C5H8N2/c6-5-7-3-1-2-4-7/h1-4H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin K using 10 uM Cbz-Phe-Arg-AMC				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50163833 ((R)-1-Cyano-pyrrolidine-2-carboxylic acid tert-but...) Show SMILES CC(C)(C)NC(=O)[C@H]1CCCN1C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin K using 10 uM Cbz-Phe-Arg-AMC				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Pro-cathepsin H (Homo sapiens (Human))	BDBM50163838 ((1-Cyano-pyrrolidin-3-yl)-carbamic acid (S)-2-cycl...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against human cathepsin H using 50 uM L-Arg-beta-naphthalamide				Bioorg Med Chem Lett 15: 1815-9 (2005) Article DOI: 10.1016/j.bmcl.2005.02.033 BindingDB Entry DOI: 10.7270/Q2DR2V1G
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%