Found 12 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
UDP-glucuronosyltransferase 1A9
(Homo sapiens (Human)) | BDBM13066
(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)Show InChI InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19) | Reactome pathway KEGG
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| 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of British Columbia
Curated by ChEMBL
| Assay Description Inhibition of 4-methylumbelliferone glucuronidation by human recombinant UGT1A9 |
Pharmacol Ther 106: 97-132 (2005)
Article DOI: 10.1016/j.pharmthera.2004.10.013 BindingDB Entry DOI: 10.7270/Q2959HZ9 |
More data for this Ligand-Target Pair | |
UDP-glucuronosyltransferase 1A7
(Homo sapiens (Human)) | BDBM13066
(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)Show InChI InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19) | Reactome pathway KEGG
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| 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of British Columbia
Curated by ChEMBL
| Assay Description Inhibition of 4-methylumbelliferone glucuronidation by human recombinant UGT1A7 |
Pharmacol Ther 106: 97-132 (2005)
Article DOI: 10.1016/j.pharmthera.2004.10.013 BindingDB Entry DOI: 10.7270/Q2959HZ9 |
More data for this Ligand-Target Pair | |
UDP-glucuronosyltransferase 1-6
(Homo sapiens (Human)) | BDBM50085045
(5-((4-((6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-...)Show SMILES Cc1c(C)c2OC(C)(COc3ccc(Cc4sc(=O)[nH]c4O)cc3)CCc2c(C)c1O Show InChI InChI=1S/C24H27NO5S/c1-13-14(2)21-18(15(3)20(13)26)9-10-24(4,30-21)12-29-17-7-5-16(6-8-17)11-19-22(27)25-23(28)31-19/h5-8,26-27H,9-12H2,1-4H3,(H,25,28) | UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
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| 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of British Columbia
Curated by ChEMBL
| Assay Description Inhibition of AZT glucuronidation by human recombinant UGT1A6 |
Pharmacol Ther 106: 97-132 (2005)
Article DOI: 10.1016/j.pharmthera.2004.10.013 BindingDB Entry DOI: 10.7270/Q2959HZ9 |
More data for this Ligand-Target Pair | |
UDP-glucuronosyltransferase 1-6
(Homo sapiens (Human)) | BDBM13066
(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)Show InChI InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19) | UniProtKB/SwissProt
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| 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of British Columbia
Curated by ChEMBL
| Assay Description Inhibition of 4-methylumbelliferone glucuronidation by human recombinant UGT1A6 |
Pharmacol Ther 106: 97-132 (2005)
Article DOI: 10.1016/j.pharmthera.2004.10.013 BindingDB Entry DOI: 10.7270/Q2959HZ9 |
More data for this Ligand-Target Pair | |
UDP-glucuronosyltransferase 1A10
(Homo sapiens (Human)) | BDBM13066
(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)Show InChI InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19) | KEGG
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| 2.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of British Columbia
Curated by ChEMBL
| Assay Description Inhibition of 4-methylumbelliferone glucuronidation by human recombinant UGT1A10 |
Pharmacol Ther 106: 97-132 (2005)
Article DOI: 10.1016/j.pharmthera.2004.10.013 BindingDB Entry DOI: 10.7270/Q2959HZ9 |
More data for this Ligand-Target Pair | |
UDP-glucuronosyltransferase 1A1
(Homo sapiens (Human)) | BDBM13066
(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)Show InChI InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19) | UniProtKB/SwissProt
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| 5.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of British Columbia
Curated by ChEMBL
| Assay Description Inhibition of 4-methylumbelliferone glucuronidation by human recombinant UGT1A1 |
Pharmacol Ther 106: 97-132 (2005)
Article DOI: 10.1016/j.pharmthera.2004.10.013 BindingDB Entry DOI: 10.7270/Q2959HZ9 |
More data for this Ligand-Target Pair | |
UDP-glucuronosyltransferase 1A7
(Homo sapiens (Human)) | BDBM50206509
(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)Show InChI InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16) | Reactome pathway KEGG
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| 9.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of British Columbia
Curated by ChEMBL
| Assay Description Inhibition of 4-methylumbelliferone glucuronidation by human recombinant UGT1A7 |
Pharmacol Ther 106: 97-132 (2005)
Article DOI: 10.1016/j.pharmthera.2004.10.013 BindingDB Entry DOI: 10.7270/Q2959HZ9 |
More data for this Ligand-Target Pair | |
UDP-glucuronosyltransferase 1A1
(Homo sapiens (Human)) | BDBM50206509
(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)Show InChI InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16) | UniProtKB/SwissProt
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| 2.21E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of British Columbia
Curated by ChEMBL
| Assay Description Inhibition of 4-methylumbelliferone glucuronidation by human recombinant UGT1A1 |
Pharmacol Ther 106: 97-132 (2005)
Article DOI: 10.1016/j.pharmthera.2004.10.013 BindingDB Entry DOI: 10.7270/Q2959HZ9 |
More data for this Ligand-Target Pair | |
UDP-glucuronosyltransferase 1A10
(Homo sapiens (Human)) | BDBM50206509
(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)Show InChI InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16) | KEGG
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| 2.31E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of British Columbia
Curated by ChEMBL
| Assay Description Inhibition of 4-methylumbelliferone glucuronidation by human recombinant UGT1A10 |
Pharmacol Ther 106: 97-132 (2005)
Article DOI: 10.1016/j.pharmthera.2004.10.013 BindingDB Entry DOI: 10.7270/Q2959HZ9 |
More data for this Ligand-Target Pair | |
UDP-glucuronosyltransferase 1-6
(Homo sapiens (Human)) | BDBM50206509
(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)Show InChI InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16) | UniProtKB/SwissProt
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| 1.43E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of British Columbia
Curated by ChEMBL
| Assay Description Inhibition of 4-methylumbelliferone glucuronidation by human recombinant UGT1A6 |
Pharmacol Ther 106: 97-132 (2005)
Article DOI: 10.1016/j.pharmthera.2004.10.013 BindingDB Entry DOI: 10.7270/Q2959HZ9 |
More data for this Ligand-Target Pair | |
UDP-glucuronosyltransferase 2B7
(Homo sapiens (Human)) | BDBM50003616
(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)Show InChI InChI=1S/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10) | PDB
UniProtKB/SwissProt
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| 1.60E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of British Columbia
Curated by ChEMBL
| Assay Description Inhibition of AZT glucuronidation by human recombinant UGT2B7 |
Pharmacol Ther 106: 97-132 (2005)
Article DOI: 10.1016/j.pharmthera.2004.10.013 BindingDB Entry DOI: 10.7270/Q2959HZ9 |
More data for this Ligand-Target Pair | |
UDP-glucuronosyltransferase 1A9
(Homo sapiens (Human)) | BDBM50206509
(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)Show InChI InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16) | Reactome pathway KEGG
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| 2.45E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of British Columbia
Curated by ChEMBL
| Assay Description Inhibition of 4-methylumbelliferone glucuronidation by human recombinant UGT1A9 |
Pharmacol Ther 106: 97-132 (2005)
Article DOI: 10.1016/j.pharmthera.2004.10.013 BindingDB Entry DOI: 10.7270/Q2959HZ9 |
More data for this Ligand-Target Pair | |