Found 93 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Melanocortin receptor 3
(Mus musculus) | BDBM50410402
(CHEMBL2096724)Show SMILES C[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C65H82N18O16/c1-34-55(90)78-48(30-51(67)86)58(93)75-35(2)54(89)77-46(27-37-13-8-5-9-14-37)62(97)82-65(3,63(98)99)83(50(53(68)88)28-39-18-22-42(85)23-19-39)52(87)31-49(79-56(91)43(66)25-38-16-20-41(84)21-17-38)61(96)81-47(29-40-32-71-33-73-40)60(95)80-45(26-36-11-6-4-7-12-36)59(94)76-44(57(92)74-34)15-10-24-72-64(69)70/h4-9,11-14,16-23,32-35,43-50,84-85H,10,15,24-31,66H2,1-3H3,(H2,67,86)(H2,68,88)(H,71,73)(H,74,92)(H,75,93)(H,76,94)(H,77,89)(H,78,90)(H,79,91)(H,80,95)(H,81,96)(H,82,97)(H,98,99)(H4,69,70,72)/t34-,35-,43-,44-,45+,46-,47-,48-,49-,50-,65?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.35E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-3 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50410406
(CHEMBL2096723)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C70H80N16O16/c1-37-60(92)79-51(28-40-14-8-5-9-15-40)68(100)85-70(3,69(101)102)86(56(59(73)91)29-42-20-24-46(88)25-21-42)58(90)33-55(81-62(94)48(71)26-41-18-22-45(87)23-19-41)67(99)83-53(31-44-35-74-36-76-44)66(98)82-50(27-39-12-6-4-7-13-39)63(95)77-38(2)61(93)80-52(30-43-34-75-49-17-11-10-16-47(43)49)65(97)84-54(32-57(72)89)64(96)78-37/h4-25,34-38,48,50-56,75,87-88H,26-33,71H2,1-3H3,(H2,72,89)(H2,73,91)(H,74,76)(H,77,95)(H,78,96)(H,79,92)(H,80,93)(H,81,94)(H,82,98)(H,83,99)(H,84,97)(H,85,100)(H,101,102)/t37-,38-,48-,50+,51-,52-,53-,54-,55-,56-,70?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 32.5 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-4 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50410410
(CHEMBL2096742 | SHU-9119)Show SMILES CCCC[C@@H](NC(C)=O)C(=O)N[C@@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C54H71N15O9/c1-3-4-15-40(63-31(2)70)48(73)69-45-27-46(71)59-21-10-9-17-39(47(55)72)64-51(76)43(25-35-28-61-38-16-8-7-14-37(35)38)67-49(74)41(18-11-22-60-54(56)57)65-50(75)42(24-32-19-20-33-12-5-6-13-34(33)23-32)66-52(77)44(68-53(45)78)26-36-29-58-30-62-36/h5-8,12-14,16,19-20,23,28-30,39-45,61H,3-4,9-11,15,17-18,21-22,24-27H2,1-2H3,(H2,55,72)(H,58,62)(H,59,71)(H,63,70)(H,64,76)(H,65,75)(H,66,77)(H,67,74)(H,68,78)(H,69,73)(H4,56,57,60)/t39-,40+,41-,42+,43-,44-,45+/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.640 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-1 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50410404
(CHEMBL2096720)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C72H86N18O16/c1-39-61(96)83-52(30-41-14-7-4-8-15-41)67(102)88-72(2,70(105)106)90(56(60(75)95)31-43-21-25-48(92)26-22-43)59(94)35-55(84-62(97)49(73)28-42-19-23-47(91)24-20-42)66(101)86-53(33-46-36-78-38-80-46)65(100)85-51(29-40-12-5-3-6-13-40)64(99)82-50(18-11-27-79-71(76)77)69(104)89-37-45-17-10-9-16-44(45)32-57(89)68(103)87-54(34-58(74)93)63(98)81-39/h3-10,12-17,19-26,36,38-39,49-57,91-92H,11,18,27-35,37,73H2,1-2H3,(H2,74,93)(H2,75,95)(H,78,80)(H,81,98)(H,82,99)(H,83,96)(H,84,97)(H,85,100)(H,86,101)(H,87,103)(H,88,102)(H,105,106)(H4,76,77,79)/t39-,49-,50-,51+,52-,53-,54-,55-,56-,57-,72?/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 42.7 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-5 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50410397
(CHEMBL2096718)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C75H88N18O16/c1-41-64(99)86-56(33-43-14-7-4-8-15-43)72(107)92-75(2,73(108)109)93(60(63(78)98)35-45-22-27-51(95)28-23-45)62(97)38-59(87-65(100)52(76)31-44-20-25-50(94)26-21-44)71(106)90-57(36-49-39-81-40-83-49)70(105)89-54(32-42-12-5-3-6-13-42)68(103)85-53(18-11-29-82-74(79)80)66(101)88-55(69(104)91-58(37-61(77)96)67(102)84-41)34-46-19-24-47-16-9-10-17-48(47)30-46/h3-10,12-17,19-28,30,39-41,52-60,94-95H,11,18,29,31-38,76H2,1-2H3,(H2,77,96)(H2,78,98)(H,81,83)(H,84,102)(H,85,103)(H,86,99)(H,87,100)(H,88,101)(H,89,105)(H,90,106)(H,91,104)(H,92,107)(H,108,109)(H4,79,80,82)/t41-,52-,53-,54+,55+,56-,57-,58-,59-,60-,75?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 6.5 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-3 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50410399
(CHEMBL2096712)Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O Show InChI InChI=1S/C50H69N15O9/c1-3-4-16-35(58-29(2)66)43(68)64-41-25-42(67)65-45(70)36(18-10-11-20-51)59-47(72)39(23-31-26-56-34-17-9-8-15-33(31)34)62-44(69)37(19-12-21-55-50(52)53)60-46(71)38(22-30-13-6-5-7-14-30)61-48(73)40(63-49(41)74)24-32-27-54-28-57-32/h5-9,13-15,17,26-28,35-41,56H,3-4,10-12,16,18-25,51H2,1-2H3,(H,54,57)(H,58,66)(H,59,72)(H,60,71)(H,61,73)(H,62,69)(H,63,74)(H,64,68)(H4,52,53,55)(H,65,67,70)/t35-,36-,37-,38+,39-,40-,41-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0530 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-4 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50410395
(CHEMBL2096731)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C73H87N17O16/c1-40-63(96)83-54(31-42-15-7-4-8-16-42)71(104)89-73(2,72(105)106)90(59(62(77)95)32-44-22-26-48(92)27-23-44)61(94)36-58(84-64(97)50(75)29-43-20-24-47(91)25-21-43)70(103)87-56(34-46-38-78-39-80-46)69(102)85-53(30-41-13-5-3-6-14-41)67(100)82-52(19-11-12-28-74)65(98)86-55(33-45-37-79-51-18-10-9-17-49(45)51)68(101)88-57(35-60(76)93)66(99)81-40/h3-10,13-18,20-27,37-40,50,52-59,79,91-92H,11-12,19,28-36,74-75H2,1-2H3,(H2,76,93)(H2,77,95)(H,78,80)(H,81,99)(H,82,100)(H,83,96)(H,84,97)(H,85,102)(H,86,98)(H,87,103)(H,88,101)(H,89,104)(H,105,106)/t40-,50-,52-,53+,54-,55-,56-,57-,58-,59-,73?/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 800 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-5 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50410396
(CHEMBL2096716)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C67H84N18O16/c1-36-56(91)78-47(29-38-13-7-4-8-14-38)62(97)83-67(2,65(100)101)85(52(55(70)90)30-40-19-23-43(87)24-20-40)54(89)33-50(79-57(92)44(68)27-39-17-21-42(86)22-18-39)61(96)81-48(31-41-34-73-35-75-41)60(95)80-46(28-37-11-5-3-6-12-37)59(94)77-45(15-9-25-74-66(71)72)64(99)84-26-10-16-51(84)63(98)82-49(32-53(69)88)58(93)76-36/h3-8,11-14,17-24,34-36,44-52,86-87H,9-10,15-16,25-33,68H2,1-2H3,(H2,69,88)(H2,70,90)(H,73,75)(H,76,93)(H,77,94)(H,78,91)(H,79,92)(H,80,95)(H,81,96)(H,82,98)(H,83,97)(H,100,101)(H4,71,72,74)/t36-,44-,45-,46+,47-,48-,49-,50-,51-,52-,67?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-1 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50410398
(CHEMBL2096721)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C70H85N17O16/c1-37-59(93)81-50(30-39-13-6-4-7-14-39)65(99)80-49(19-12-28-76-69(74)75)62(96)84-52(33-43-36-77-48-18-11-10-17-46(43)48)66(100)85-53(34-56(72)90)63(97)78-38(2)60(94)82-51(31-40-15-8-5-9-16-40)67(101)86-70(3,68(102)103)87(55(58(73)92)32-42-22-26-45(89)27-23-42)57(91)35-54(64(98)79-37)83-61(95)47(71)29-41-20-24-44(88)25-21-41/h4-11,13-18,20-27,36-38,47,49-55,77,88-89H,12,19,28-35,71H2,1-3H3,(H2,72,90)(H2,73,92)(H,78,97)(H,79,98)(H,80,99)(H,81,93)(H,82,94)(H,83,95)(H,84,96)(H,85,100)(H,86,101)(H,102,103)(H4,74,75,76)/t37-,38-,47-,49-,50+,51-,52-,53-,54-,55-,70?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 29 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-3 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50410403
(CHEMBL2096717)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C75H88N18O16/c1-41-64(99)86-56(33-43-14-7-4-8-15-43)72(107)92-75(2,73(108)109)93(60(63(78)98)35-45-22-27-51(95)28-23-45)62(97)38-59(87-65(100)52(76)31-44-20-25-50(94)26-21-44)71(106)90-57(36-49-39-81-40-83-49)70(105)89-54(32-42-12-5-3-6-13-42)68(103)85-53(18-11-29-82-74(79)80)66(101)88-55(69(104)91-58(37-61(77)96)67(102)84-41)34-46-19-24-47-16-9-10-17-48(47)30-46/h3-10,12-17,19-28,30,39-41,52-60,94-95H,11,18,29,31-38,76H2,1-2H3,(H2,77,96)(H2,78,98)(H,81,83)(H,84,102)(H,85,103)(H,86,99)(H,87,100)(H,88,101)(H,89,105)(H,90,106)(H,91,104)(H,92,107)(H,108,109)(H4,79,80,82)/t41-,52-,53-,54+,55-,56-,57-,58-,59-,60-,75?/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.93 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-5 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50410394
(CHEMBL2096719)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2ccc(cc2)-c2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C77H90N18O16/c1-43-66(101)88-58(35-45-15-8-4-9-16-45)74(109)94-77(2,75(110)111)95(62(65(80)100)37-48-24-30-53(97)31-25-48)64(99)40-61(89-67(102)54(78)33-46-22-28-52(96)29-23-46)73(108)92-59(38-51-41-83-42-85-51)72(107)91-56(34-44-13-6-3-7-14-44)70(105)87-55(19-12-32-84-76(81)82)68(103)90-57(71(106)93-60(39-63(79)98)69(104)86-43)36-47-20-26-50(27-21-47)49-17-10-5-11-18-49/h3-11,13-18,20-31,41-43,54-62,96-97H,12,19,32-40,78H2,1-2H3,(H2,79,98)(H2,80,100)(H,83,85)(H,86,104)(H,87,105)(H,88,101)(H,89,102)(H,90,103)(H,91,107)(H,92,108)(H,93,106)(H,94,109)(H,110,111)(H4,81,82,84)/t43-,54-,55-,56+,57-,58-,59-,60-,61-,62-,77?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 42.6 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-4 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50410403
(CHEMBL2096717)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C75H88N18O16/c1-41-64(99)86-56(33-43-14-7-4-8-15-43)72(107)92-75(2,73(108)109)93(60(63(78)98)35-45-22-27-51(95)28-23-45)62(97)38-59(87-65(100)52(76)31-44-20-25-50(94)26-21-44)71(106)90-57(36-49-39-81-40-83-49)70(105)89-54(32-42-12-5-3-6-13-42)68(103)85-53(18-11-29-82-74(79)80)66(101)88-55(69(104)91-58(37-61(77)96)67(102)84-41)34-46-19-24-47-16-9-10-17-48(47)30-46/h3-10,12-17,19-28,30,39-41,52-60,94-95H,11,18,29,31-38,76H2,1-2H3,(H2,77,96)(H2,78,98)(H,81,83)(H,84,102)(H,85,103)(H,86,99)(H,87,100)(H,88,101)(H,89,105)(H,90,106)(H,91,104)(H,92,107)(H,108,109)(H4,79,80,82)/t41-,52-,53-,54+,55-,56-,57-,58-,59-,60-,75?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.270 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-4 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50121900
(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)Show SMILES CCCC[C@H](NC(=O)C(CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C(C)C)C(N)=O Show InChI InChI=1S/C78H111N21O19/c1-5-6-19-52(91-75(116)61(41-101)97-72(113)57(34-46-24-26-49(103)27-25-46)94-74(115)60(40-100)88-44(4)102)68(109)92-54(28-29-64(105)106)70(111)96-59(36-48-38-83-42-87-48)73(114)93-56(33-45-16-8-7-9-17-45)71(112)90-53(22-14-31-84-78(81)82)69(110)95-58(35-47-37-85-51-20-11-10-18-50(47)51)67(108)86-39-63(104)89-55(21-12-13-30-79)77(118)99-32-15-23-62(99)76(117)98-65(43(2)3)66(80)107/h7-11,16-18,20,24-27,37-38,42-43,52-62,65,85,100-101,103H,5-6,12-15,19,21-23,28-36,39-41,79H2,1-4H3,(H2,80,107)(H,83,87)(H,86,108)(H,88,102)(H,89,104)(H,90,112)(H,91,116)(H,92,109)(H,93,114)(H,94,115)(H,95,110)(H,96,111)(H,97,113)(H,98,117)(H,105,106)(H4,81,82,84)/t52-,53-,54-,55-,56+,57-,58-,59-,60-,61?,62+,65+/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0180 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-1 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50410404
(CHEMBL2096720)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C72H86N18O16/c1-39-61(96)83-52(30-41-14-7-4-8-15-41)67(102)88-72(2,70(105)106)90(56(60(75)95)31-43-21-25-48(92)26-22-43)59(94)35-55(84-62(97)49(73)28-42-19-23-47(91)24-20-42)66(101)86-53(33-46-36-78-38-80-46)65(100)85-51(29-40-12-5-3-6-13-40)64(99)82-50(18-11-27-79-71(76)77)69(104)89-37-45-17-10-9-16-44(45)32-57(89)68(103)87-54(34-58(74)93)63(98)81-39/h3-10,12-17,19-26,36,38-39,49-57,91-92H,11,18,27-35,37,73H2,1-2H3,(H2,74,93)(H2,75,95)(H,78,80)(H,81,98)(H,82,99)(H,83,96)(H,84,97)(H,85,100)(H,86,101)(H,87,103)(H,88,102)(H,105,106)(H4,76,77,79)/t39-,49-,50-,51+,52-,53-,54-,55-,56-,57-,72?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-3 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50410394
(CHEMBL2096719)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2ccc(cc2)-c2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C77H90N18O16/c1-43-66(101)88-58(35-45-15-8-4-9-16-45)74(109)94-77(2,75(110)111)95(62(65(80)100)37-48-24-30-53(97)31-25-48)64(99)40-61(89-67(102)54(78)33-46-22-28-52(96)29-23-46)73(108)92-59(38-51-41-83-42-85-51)72(107)91-56(34-44-13-6-3-7-14-44)70(105)87-55(19-12-32-84-76(81)82)68(103)90-57(71(106)93-60(39-63(79)98)69(104)86-43)36-47-20-26-50(27-21-47)49-17-10-5-11-18-49/h3-11,13-18,20-31,41-43,54-62,96-97H,12,19,32-40,78H2,1-2H3,(H2,79,98)(H2,80,100)(H,83,85)(H,86,104)(H,87,105)(H,88,101)(H,89,102)(H,90,103)(H,91,107)(H,92,108)(H,93,106)(H,94,109)(H,110,111)(H4,81,82,84)/t43-,54-,55-,56+,57-,58-,59-,60-,61-,62-,77?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 11.6 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-1 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50410413
(CHEMBL2096730)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C72H82N16O16/c1-39-62(94)80-51(29-40-12-5-3-6-13-40)68(100)86-72(2,71(103)104)88(58(61(75)93)31-43-21-25-47(90)26-22-43)60(92)35-55(81-63(95)49(73)28-42-19-23-46(89)24-20-42)67(99)82-53(33-45-37-76-38-78-45)66(98)85-56(30-41-14-7-4-8-15-41)70(102)87-27-11-18-57(87)69(101)84-52(32-44-36-77-50-17-10-9-16-48(44)50)65(97)83-54(34-59(74)91)64(96)79-39/h3-10,12-17,19-26,36-39,49,51-58,77,89-90H,11,18,27-35,73H2,1-2H3,(H2,74,91)(H2,75,93)(H,76,78)(H,79,96)(H,80,94)(H,81,95)(H,82,99)(H,83,97)(H,84,101)(H,85,98)(H,86,100)(H,103,104)/t39-,49-,51-,52-,53-,54-,55-,56+,57-,58-,72?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 990 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-1 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50410413
(CHEMBL2096730)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C72H82N16O16/c1-39-62(94)80-51(29-40-12-5-3-6-13-40)68(100)86-72(2,71(103)104)88(58(61(75)93)31-43-21-25-47(90)26-22-43)60(92)35-55(81-63(95)49(73)28-42-19-23-46(89)24-20-42)67(99)82-53(33-45-37-76-38-78-45)66(98)85-56(30-41-14-7-4-8-15-41)70(102)87-27-11-18-57(87)69(101)84-52(32-44-36-77-50-17-10-9-16-48(44)50)65(97)83-54(34-59(74)91)64(96)79-39/h3-10,12-17,19-26,36-39,49,51-58,77,89-90H,11,18,27-35,73H2,1-2H3,(H2,74,91)(H2,75,93)(H,76,78)(H,79,96)(H,80,94)(H,81,95)(H,82,99)(H,83,97)(H,84,101)(H,85,98)(H,86,100)(H,103,104)/t39-,49-,51-,52-,53-,54-,55-,56+,57-,58-,72?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.30E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-4 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50410393
(CHEMBL2096819)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C73H87N19O16/c1-39-62(98)85-53(30-41-14-7-4-8-15-41)70(106)91-73(2,71(107)108)92(58(61(76)97)31-43-21-25-47(94)26-22-43)60(96)35-57(86-63(99)49(74)28-42-19-23-46(93)24-20-42)69(105)89-55(33-45-37-79-38-82-45)68(104)87-52(29-40-12-5-3-6-13-40)66(102)84-51(18-11-27-80-72(77)78)64(100)88-54(32-44-36-81-50-17-10-9-16-48(44)50)67(103)90-56(34-59(75)95)65(101)83-39/h3-10,12-17,19-26,36-39,49,51-58,81,93-94H,11,18,27-35,74H2,1-2H3,(H2,75,95)(H2,76,97)(H,79,82)(H,83,101)(H,84,102)(H,85,98)(H,86,99)(H,87,104)(H,88,100)(H,89,105)(H,90,103)(H,91,106)(H,107,108)(H4,77,78,80)/t39-,49-,51-,52+,53+,54-,55-,56-,57-,58-,73?/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.87 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-5 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50410408
(CHEMBL2096713)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C73H87N19O16/c1-39-62(98)85-53(30-41-14-7-4-8-15-41)70(106)91-73(2,71(107)108)92(58(61(76)97)31-43-21-25-47(94)26-22-43)60(96)35-57(86-63(99)49(74)28-42-19-23-46(93)24-20-42)69(105)89-55(33-45-37-79-38-82-45)68(104)87-52(29-40-12-5-3-6-13-40)66(102)84-51(18-11-27-80-72(77)78)64(100)88-54(32-44-36-81-50-17-10-9-16-48(44)50)67(103)90-56(34-59(75)95)65(101)83-39/h3-10,12-17,19-26,36-39,49,51-58,81,93-94H,11,18,27-35,74H2,1-2H3,(H2,75,95)(H2,76,97)(H,79,82)(H,83,101)(H,84,102)(H,85,98)(H,86,99)(H,87,104)(H,88,100)(H,89,105)(H,90,103)(H,91,106)(H,107,108)(H4,77,78,80)/t39-,49-,51-,52+,53-,54-,55-,56-,57-,58-,73?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.130 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-4 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50410398
(CHEMBL2096721)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C70H85N17O16/c1-37-59(93)81-50(30-39-13-6-4-7-14-39)65(99)80-49(19-12-28-76-69(74)75)62(96)84-52(33-43-36-77-48-18-11-10-17-46(43)48)66(100)85-53(34-56(72)90)63(97)78-38(2)60(94)82-51(31-40-15-8-5-9-16-40)67(101)86-70(3,68(102)103)87(55(58(73)92)32-42-22-26-45(89)27-23-42)57(91)35-54(64(98)79-37)83-61(95)47(71)29-41-20-24-44(88)25-21-41/h4-11,13-18,20-27,36-38,47,49-55,77,88-89H,12,19,28-35,71H2,1-3H3,(H2,72,90)(H2,73,92)(H,78,97)(H,79,98)(H,80,99)(H,81,93)(H,82,94)(H,83,95)(H,84,96)(H,85,100)(H,86,101)(H,102,103)(H4,74,75,76)/t37-,38-,47-,49-,50+,51-,52-,53-,54-,55-,70?/m0/s1 | PDB
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.360 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-4 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50121900
(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)Show SMILES CCCC[C@H](NC(=O)C(CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C(C)C)C(N)=O Show InChI InChI=1S/C78H111N21O19/c1-5-6-19-52(91-75(116)61(41-101)97-72(113)57(34-46-24-26-49(103)27-25-46)94-74(115)60(40-100)88-44(4)102)68(109)92-54(28-29-64(105)106)70(111)96-59(36-48-38-83-42-87-48)73(114)93-56(33-45-16-8-7-9-17-45)71(112)90-53(22-14-31-84-78(81)82)69(110)95-58(35-47-37-85-51-20-11-10-18-50(47)51)67(108)86-39-63(104)89-55(21-12-13-30-79)77(118)99-32-15-23-62(99)76(117)98-65(43(2)3)66(80)107/h7-11,16-18,20,24-27,37-38,42-43,52-62,65,85,100-101,103H,5-6,12-15,19,21-23,28-36,39-41,79H2,1-4H3,(H2,80,107)(H,83,87)(H,86,108)(H,88,102)(H,89,104)(H,90,112)(H,91,116)(H,92,109)(H,93,114)(H,94,115)(H,95,110)(H,96,111)(H,97,113)(H,98,117)(H,105,106)(H4,81,82,84)/t52-,53-,54-,55-,56+,57-,58-,59-,60-,61?,62+,65+/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0950 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-5 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50029747
((4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S...)Show SMILES CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O Show InChI InChI=1S/C77H109N21O19S/c1-42(2)64(65(79)106)97-75(116)61-20-13-30-98(61)76(117)54(18-10-11-28-78)88-62(103)38-85-66(107)57(34-46-36-84-50-17-9-8-16-49(46)50)94-67(108)51(19-12-29-83-77(80)81)89-70(111)55(32-44-14-6-5-7-15-44)92-72(113)58(35-47-37-82-41-86-47)95-68(109)52(25-26-63(104)105)90-69(110)53(27-31-118-4)91-74(115)60(40-100)96-71(112)56(33-45-21-23-48(102)24-22-45)93-73(114)59(39-99)87-43(3)101/h5-9,14-17,21-24,36-37,41-42,51-61,64,84,99-100,102H,10-13,18-20,25-35,38-40,78H2,1-4H3,(H2,79,106)(H,82,86)(H,85,107)(H,87,101)(H,88,103)(H,89,111)(H,90,110)(H,91,115)(H,92,113)(H,93,114)(H,94,108)(H,95,109)(H,96,112)(H,97,116)(H,104,105)(H4,80,81,83)/t51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,64-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.570 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-3 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50410395
(CHEMBL2096731)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C73H87N17O16/c1-40-63(96)83-54(31-42-15-7-4-8-16-42)71(104)89-73(2,72(105)106)90(59(62(77)95)32-44-22-26-48(92)27-23-44)61(94)36-58(84-64(97)50(75)29-43-20-24-47(91)25-21-43)70(103)87-56(34-46-38-78-39-80-46)69(102)85-53(30-41-13-5-3-6-14-41)67(100)82-52(19-11-12-28-74)65(98)86-55(33-45-37-79-51-18-10-9-17-49(45)51)68(101)88-57(35-60(76)93)66(99)81-40/h3-10,13-18,20-27,37-40,50,52-59,79,91-92H,11-12,19,28-36,74-75H2,1-2H3,(H2,76,93)(H2,77,95)(H,78,80)(H,81,99)(H,82,100)(H,83,96)(H,84,97)(H,85,102)(H,86,98)(H,87,103)(H,88,101)(H,89,104)(H,105,106)/t40-,50-,52-,53+,54-,55-,56-,57-,58-,59-,73?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 680 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-1 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50410407
(CHEMBL2096715)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)C2(CCc3ccccc3C2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C78H91N17O16/c1-43-66(101)88-58(36-45-16-7-4-8-17-45)72(107)93-77(2,75(110)111)95(62(65(81)100)37-47-25-29-52(97)30-26-47)64(99)40-61(89-67(102)54(79)34-46-23-27-51(96)28-24-46)73(108)94-78(32-31-48-18-9-10-19-49(48)41-78)74(109)92-57(35-44-14-5-3-6-15-44)70(105)87-56(22-13-33-84-76(82)83)68(103)90-59(38-50-42-85-55-21-12-11-20-53(50)55)71(106)91-60(39-63(80)98)69(104)86-43/h3-12,14-21,23-30,42-43,54,56-62,85,96-97H,13,22,31-41,79H2,1-2H3,(H2,80,98)(H2,81,100)(H,86,104)(H,87,105)(H,88,101)(H,89,102)(H,90,103)(H,91,106)(H,92,109)(H,93,107)(H,94,108)(H,110,111)(H4,82,83,84)/t43-,54-,56-,57+,58-,59-,60-,61-,62-,77?,78?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 115 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-4 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50410399
(CHEMBL2096712)Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O Show InChI InChI=1S/C50H69N15O9/c1-3-4-16-35(58-29(2)66)43(68)64-41-25-42(67)65-45(70)36(18-10-11-20-51)59-47(72)39(23-31-26-56-34-17-9-8-15-33(31)34)62-44(69)37(19-12-21-55-50(52)53)60-46(71)38(22-30-13-6-5-7-14-30)61-48(73)40(63-49(41)74)24-32-27-54-28-57-32/h5-9,13-15,17,26-28,35-41,56H,3-4,10-12,16,18-25,51H2,1-2H3,(H,54,57)(H,58,66)(H,59,72)(H,60,71)(H,61,73)(H,62,69)(H,63,74)(H,64,68)(H4,52,53,55)(H,65,67,70)/t35-,36-,37-,38+,39-,40-,41-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0680 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-5 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50410414
(CHEMBL2096714)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C76H89N17O16/c1-42-65(99)86-57(36-45-19-10-5-11-20-45)73(107)92-76(2,74(108)109)93(61(64(79)98)37-47-26-30-50(95)31-27-47)63(97)40-60(87-66(100)52(77)33-46-24-28-49(94)29-25-46)72(106)89-56(35-44-17-8-4-9-18-44)70(104)88-55(34-43-15-6-3-7-16-43)69(103)85-54(23-14-32-82-75(80)81)67(101)90-58(38-48-41-83-53-22-13-12-21-51(48)53)71(105)91-59(39-62(78)96)68(102)84-42/h3-13,15-22,24-31,41-42,52,54-61,83,94-95H,14,23,32-40,77H2,1-2H3,(H2,78,96)(H2,79,98)(H,84,102)(H,85,103)(H,86,99)(H,87,100)(H,88,104)(H,89,106)(H,90,101)(H,91,105)(H,92,107)(H,108,109)(H4,80,81,82)/t42-,52-,54-,55+,56-,57-,58-,59-,60-,61-,76?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 6.04 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-1 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50410414
(CHEMBL2096714)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C76H89N17O16/c1-42-65(99)86-57(36-45-19-10-5-11-20-45)73(107)92-76(2,74(108)109)93(61(64(79)98)37-47-26-30-50(95)31-27-47)63(97)40-60(87-66(100)52(77)33-46-24-28-49(94)29-25-46)72(106)89-56(35-44-17-8-4-9-18-44)70(104)88-55(34-43-15-6-3-7-16-43)69(103)85-54(23-14-32-82-75(80)81)67(101)90-58(38-48-41-83-53-22-13-12-21-51(48)53)71(105)91-59(39-62(78)96)68(102)84-42/h3-13,15-22,24-31,41-42,52,54-61,83,94-95H,14,23,32-40,77H2,1-2H3,(H2,78,96)(H2,79,98)(H,84,102)(H,85,103)(H,86,99)(H,87,100)(H,88,104)(H,89,106)(H,90,101)(H,91,105)(H,92,107)(H,108,109)(H4,80,81,82)/t42-,52-,54-,55+,56-,57-,58-,59-,60-,61-,76?/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.15 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-5 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50410402
(CHEMBL2096724)Show SMILES C[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C65H82N18O16/c1-34-55(90)78-48(30-51(67)86)58(93)75-35(2)54(89)77-46(27-37-13-8-5-9-14-37)62(97)82-65(3,63(98)99)83(50(53(68)88)28-39-18-22-42(85)23-19-39)52(87)31-49(79-56(91)43(66)25-38-16-20-41(84)21-17-38)61(96)81-47(29-40-32-71-33-73-40)60(95)80-45(26-36-11-6-4-7-12-36)59(94)76-44(57(92)74-34)15-10-24-72-64(69)70/h4-9,11-14,16-23,32-35,43-50,84-85H,10,15,24-31,66H2,1-3H3,(H2,67,86)(H2,68,88)(H,71,73)(H,74,92)(H,75,93)(H,76,94)(H,77,89)(H,78,90)(H,79,91)(H,80,95)(H,81,96)(H,82,97)(H,98,99)(H4,69,70,72)/t34-,35-,43-,44-,45+,46-,47-,48-,49-,50-,65?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 710 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-4 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50410405
(CHEMBL2096726)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C69H85N19O16/c1-36-58(94)81-48(27-37-10-4-3-5-11-37)64(100)86-69(2,67(103)104)88(54(57(72)93)28-39-18-22-43(90)23-19-39)56(92)32-51(82-59(95)45(70)26-38-16-20-42(89)21-17-38)63(99)85-52(30-41-34-75-35-78-41)66(102)87-25-9-15-53(87)65(101)80-47(14-8-24-76-68(73)74)60(96)83-49(29-40-33-77-46-13-7-6-12-44(40)46)62(98)84-50(31-55(71)91)61(97)79-36/h3-7,10-13,16-23,33-36,45,47-54,77,89-90H,8-9,14-15,24-32,70H2,1-2H3,(H2,71,91)(H2,72,93)(H,75,78)(H,79,97)(H,80,101)(H,81,94)(H,82,95)(H,83,96)(H,84,98)(H,85,99)(H,86,100)(H,103,104)(H4,73,74,76)/t36-,45-,47-,48-,49-,50-,51-,52-,53-,54-,69?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.32E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-3 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50410415
(CHEMBL2096722)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C67H83N19O16/c1-34-56(92)79-46(14-9-23-74-66(71)72)59(95)82-48(27-39-31-75-45-13-8-7-12-43(39)45)62(98)84-50(29-53(69)89)61(97)78-35(2)57(93)80-47(25-36-10-5-4-6-11-36)64(100)85-67(3,65(101)102)86(52(55(70)91)26-38-17-21-42(88)22-18-38)54(90)30-51(81-58(94)44(68)24-37-15-19-41(87)20-16-37)63(99)83-49(60(96)77-34)28-40-32-73-33-76-40/h4-8,10-13,15-22,31-35,44,46-52,75,87-88H,9,14,23-30,68H2,1-3H3,(H2,69,89)(H2,70,91)(H,73,76)(H,77,96)(H,78,97)(H,79,92)(H,80,93)(H,81,94)(H,82,95)(H,83,99)(H,84,98)(H,85,100)(H,101,102)(H4,71,72,74)/t34-,35-,44-,46-,47-,48-,49-,50-,51-,52-,67?/m0/s1 | UniProtKB/SwissProt
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| CHEMBL
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PC sid
UniChem
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PubMed
| n/a | n/a | n/a | n/a | 690 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-5 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50410403
(CHEMBL2096717)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C75H88N18O16/c1-41-64(99)86-56(33-43-14-7-4-8-15-43)72(107)92-75(2,73(108)109)93(60(63(78)98)35-45-22-27-51(95)28-23-45)62(97)38-59(87-65(100)52(76)31-44-20-25-50(94)26-21-44)71(106)90-57(36-49-39-81-40-83-49)70(105)89-54(32-42-12-5-3-6-13-42)68(103)85-53(18-11-29-82-74(79)80)66(101)88-55(69(104)91-58(37-61(77)96)67(102)84-41)34-46-19-24-47-16-9-10-17-48(47)30-46/h3-10,12-17,19-28,30,39-41,52-60,94-95H,11,18,29,31-38,76H2,1-2H3,(H2,77,96)(H2,78,98)(H,81,83)(H,84,102)(H,85,103)(H,86,99)(H,87,100)(H,88,101)(H,89,105)(H,90,106)(H,91,104)(H,92,107)(H,108,109)(H4,79,80,82)/t41-,52-,53-,54+,55-,56-,57-,58-,59-,60-,75?/m0/s1 | KEGG
UniProtKB/SwissProt
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| CHEMBL
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | n/a | n/a | 0.530 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-1 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50410394
(CHEMBL2096719)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2ccc(cc2)-c2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C77H90N18O16/c1-43-66(101)88-58(35-45-15-8-4-9-16-45)74(109)94-77(2,75(110)111)95(62(65(80)100)37-48-24-30-53(97)31-25-48)64(99)40-61(89-67(102)54(78)33-46-22-28-52(96)29-23-46)73(108)92-59(38-51-41-83-42-85-51)72(107)91-56(34-44-13-6-3-7-14-44)70(105)87-55(19-12-32-84-76(81)82)68(103)90-57(71(106)93-60(39-63(79)98)69(104)86-43)36-47-20-26-50(27-21-47)49-17-10-5-11-18-49/h3-11,13-18,20-31,41-43,54-62,96-97H,12,19,32-40,78H2,1-2H3,(H2,79,98)(H2,80,100)(H,83,85)(H,86,104)(H,87,105)(H,88,101)(H,89,102)(H,90,103)(H,91,107)(H,92,108)(H,93,106)(H,94,109)(H,110,111)(H4,81,82,84)/t43-,54-,55-,56+,57-,58-,59-,60-,61-,62-,77?/m0/s1 | UniProtKB/SwissProt
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | n/a | n/a | 3.43 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-5 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50121900
(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)Show SMILES CCCC[C@H](NC(=O)C(CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C(C)C)C(N)=O Show InChI InChI=1S/C78H111N21O19/c1-5-6-19-52(91-75(116)61(41-101)97-72(113)57(34-46-24-26-49(103)27-25-46)94-74(115)60(40-100)88-44(4)102)68(109)92-54(28-29-64(105)106)70(111)96-59(36-48-38-83-42-87-48)73(114)93-56(33-45-16-8-7-9-17-45)71(112)90-53(22-14-31-84-78(81)82)69(110)95-58(35-47-37-85-51-20-11-10-18-50(47)51)67(108)86-39-63(104)89-55(21-12-13-30-79)77(118)99-32-15-23-62(99)76(117)98-65(43(2)3)66(80)107/h7-11,16-18,20,24-27,37-38,42-43,52-62,65,85,100-101,103H,5-6,12-15,19,21-23,28-36,39-41,79H2,1-4H3,(H2,80,107)(H,83,87)(H,86,108)(H,88,102)(H,89,104)(H,90,112)(H,91,116)(H,92,109)(H,93,114)(H,94,115)(H,95,110)(H,96,111)(H,97,113)(H,98,117)(H,105,106)(H4,81,82,84)/t52-,53-,54-,55-,56+,57-,58-,59-,60-,61?,62+,65+/m0/s1 | PDB
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UniChem
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| n/a | n/a | n/a | n/a | 0.160 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-4 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50029747
((4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S...)Show SMILES CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O Show InChI InChI=1S/C77H109N21O19S/c1-42(2)64(65(79)106)97-75(116)61-20-13-30-98(61)76(117)54(18-10-11-28-78)88-62(103)38-85-66(107)57(34-46-36-84-50-17-9-8-16-49(46)50)94-67(108)51(19-12-29-83-77(80)81)89-70(111)55(32-44-14-6-5-7-15-44)92-72(113)58(35-47-37-82-41-86-47)95-68(109)52(25-26-63(104)105)90-69(110)53(27-31-118-4)91-74(115)60(40-100)96-71(112)56(33-45-21-23-48(102)24-22-45)93-73(114)59(39-99)87-43(3)101/h5-9,14-17,21-24,36-37,41-42,51-61,64,84,99-100,102H,10-13,18-20,25-35,38-40,78H2,1-4H3,(H2,79,106)(H,82,86)(H,85,107)(H,87,101)(H,88,103)(H,89,111)(H,90,110)(H,91,115)(H,92,113)(H,93,114)(H,94,108)(H,95,109)(H,96,112)(H,97,116)(H,104,105)(H4,80,81,83)/t51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,64-/m0/s1 | PDB
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| n/a | n/a | n/a | n/a | 1.93 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-4 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50029747
((4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S...)Show SMILES CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O Show InChI InChI=1S/C77H109N21O19S/c1-42(2)64(65(79)106)97-75(116)61-20-13-30-98(61)76(117)54(18-10-11-28-78)88-62(103)38-85-66(107)57(34-46-36-84-50-17-9-8-16-49(46)50)94-67(108)51(19-12-29-83-77(80)81)89-70(111)55(32-44-14-6-5-7-15-44)92-72(113)58(35-47-37-82-41-86-47)95-68(109)52(25-26-63(104)105)90-69(110)53(27-31-118-4)91-74(115)60(40-100)96-71(112)56(33-45-21-23-48(102)24-22-45)93-73(114)59(39-99)87-43(3)101/h5-9,14-17,21-24,36-37,41-42,51-61,64,84,99-100,102H,10-13,18-20,25-35,38-40,78H2,1-4H3,(H2,79,106)(H,82,86)(H,85,107)(H,87,101)(H,88,103)(H,89,111)(H,90,110)(H,91,115)(H,92,113)(H,93,114)(H,94,108)(H,95,109)(H,96,112)(H,97,116)(H,104,105)(H4,80,81,83)/t51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,64-/m0/s1 | KEGG
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UniChem
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| n/a | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-1 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50410400
(CHEMBL2096818)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2cccc3ccccc23)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C77H89N19O16/c1-41-66(102)89-56(31-42-12-4-3-5-13-42)74(110)95-77(2,75(111)112)96(62(65(80)101)32-44-23-27-50(98)28-24-44)64(100)37-61(90-67(103)53(78)30-43-21-25-49(97)26-22-43)73(109)93-59(35-48-39-83-40-86-48)72(108)92-57(33-46-16-10-15-45-14-6-7-17-51(45)46)70(106)88-55(20-11-29-84-76(81)82)68(104)91-58(34-47-38-85-54-19-9-8-18-52(47)54)71(107)94-60(36-63(79)99)69(105)87-41/h3-10,12-19,21-28,38-41,53,55-62,85,97-98H,11,20,29-37,78H2,1-2H3,(H2,79,99)(H2,80,101)(H,83,86)(H,87,105)(H,88,106)(H,89,102)(H,90,103)(H,91,104)(H,92,108)(H,93,109)(H,94,107)(H,95,110)(H,111,112)(H4,81,82,84)/t41-,53-,55-,56-,57+,58-,59-,60-,61-,62-,77?/m0/s1 | PDB
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| n/a | n/a | n/a | n/a | 320 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-3 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50410401
(CHEMBL2096729)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccc(cc2)-c2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C79H91N19O16/c1-43-68(104)91-59(33-44-12-5-3-6-13-44)76(112)97-79(2,77(113)114)98(64(67(82)103)35-47-23-29-53(100)30-24-47)66(102)39-63(92-69(105)55(80)32-45-21-27-52(99)28-22-45)75(111)95-61(37-51-41-85-42-88-51)74(110)93-58(34-46-19-25-49(26-20-46)48-14-7-4-8-15-48)72(108)90-57(18-11-31-86-78(83)84)70(106)94-60(36-50-40-87-56-17-10-9-16-54(50)56)73(109)96-62(38-65(81)101)71(107)89-43/h3-10,12-17,19-30,40-43,55,57-64,87,99-100H,11,18,31-39,80H2,1-2H3,(H2,81,101)(H2,82,103)(H,85,88)(H,89,107)(H,90,108)(H,91,104)(H,92,105)(H,93,110)(H,94,106)(H,95,111)(H,96,109)(H,97,112)(H,113,114)(H4,83,84,86)/t43-,55-,57-,58+,59-,60-,61-,62-,63-,64-,79?/m0/s1 | KEGG
UniProtKB/SwissProt
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | n/a | n/a | 3.87 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-1 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50410402
(CHEMBL2096724)Show SMILES C[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C65H82N18O16/c1-34-55(90)78-48(30-51(67)86)58(93)75-35(2)54(89)77-46(27-37-13-8-5-9-14-37)62(97)82-65(3,63(98)99)83(50(53(68)88)28-39-18-22-42(85)23-19-39)52(87)31-49(79-56(91)43(66)25-38-16-20-41(84)21-17-38)61(96)81-47(29-40-32-71-33-73-40)60(95)80-45(26-36-11-6-4-7-12-36)59(94)76-44(57(92)74-34)15-10-24-72-64(69)70/h4-9,11-14,16-23,32-35,43-50,84-85H,10,15,24-31,66H2,1-3H3,(H2,67,86)(H2,68,88)(H,71,73)(H,74,92)(H,75,93)(H,76,94)(H,77,89)(H,78,90)(H,79,91)(H,80,95)(H,81,96)(H,82,97)(H,98,99)(H4,69,70,72)/t34-,35-,43-,44-,45+,46-,47-,48-,49-,50-,65?/m0/s1 | UniProtKB/SwissProt
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UniChem
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PubMed
| n/a | n/a | n/a | n/a | 50.1 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-5 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50410405
(CHEMBL2096726)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C69H85N19O16/c1-36-58(94)81-48(27-37-10-4-3-5-11-37)64(100)86-69(2,67(103)104)88(54(57(72)93)28-39-18-22-43(90)23-19-39)56(92)32-51(82-59(95)45(70)26-38-16-20-42(89)21-17-38)63(99)85-52(30-41-34-75-35-78-41)66(102)87-25-9-15-53(87)65(101)80-47(14-8-24-76-68(73)74)60(96)83-49(29-40-33-77-46-13-7-6-12-44(40)46)62(98)84-50(31-55(71)91)61(97)79-36/h3-7,10-13,16-23,33-36,45,47-54,77,89-90H,8-9,14-15,24-32,70H2,1-2H3,(H2,71,91)(H2,72,93)(H,75,78)(H,79,97)(H,80,101)(H,81,94)(H,82,95)(H,83,96)(H,84,98)(H,85,99)(H,86,100)(H,103,104)(H4,73,74,76)/t36-,45-,47-,48-,49-,50-,51-,52-,53-,54-,69?/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.90E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-5 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50410404
(CHEMBL2096720)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C72H86N18O16/c1-39-61(96)83-52(30-41-14-7-4-8-15-41)67(102)88-72(2,70(105)106)90(56(60(75)95)31-43-21-25-48(92)26-22-43)59(94)35-55(84-62(97)49(73)28-42-19-23-47(91)24-20-42)66(101)86-53(33-46-36-78-38-80-46)65(100)85-51(29-40-12-5-3-6-13-40)64(99)82-50(18-11-27-79-71(76)77)69(104)89-37-45-17-10-9-16-44(45)32-57(89)68(103)87-54(34-58(74)93)63(98)81-39/h3-10,12-17,19-26,36,38-39,49-57,91-92H,11,18,27-35,37,73H2,1-2H3,(H2,74,93)(H2,75,95)(H,78,80)(H,81,98)(H,82,99)(H,83,96)(H,84,97)(H,85,100)(H,86,101)(H,87,103)(H,88,102)(H,105,106)(H4,76,77,79)/t39-,49-,50-,51+,52-,53-,54-,55-,56-,57-,72?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 21.6 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-1 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50410414
(CHEMBL2096714)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C76H89N17O16/c1-42-65(99)86-57(36-45-19-10-5-11-20-45)73(107)92-76(2,74(108)109)93(61(64(79)98)37-47-26-30-50(95)31-27-47)63(97)40-60(87-66(100)52(77)33-46-24-28-49(94)29-25-46)72(106)89-56(35-44-17-8-4-9-18-44)70(104)88-55(34-43-15-6-3-7-16-43)69(103)85-54(23-14-32-82-75(80)81)67(101)90-58(38-48-41-83-53-22-13-12-21-51(48)53)71(105)91-59(39-62(78)96)68(102)84-42/h3-13,15-22,24-31,41-42,52,54-61,83,94-95H,14,23,32-40,77H2,1-2H3,(H2,78,96)(H2,79,98)(H,84,102)(H,85,103)(H,86,99)(H,87,100)(H,88,104)(H,89,106)(H,90,101)(H,91,105)(H,92,107)(H,108,109)(H4,80,81,82)/t42-,52-,54-,55+,56-,57-,58-,59-,60-,61-,76?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.640 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-4 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50410396
(CHEMBL2096716)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C67H84N18O16/c1-36-56(91)78-47(29-38-13-7-4-8-14-38)62(97)83-67(2,65(100)101)85(52(55(70)90)30-40-19-23-43(87)24-20-40)54(89)33-50(79-57(92)44(68)27-39-17-21-42(86)22-18-39)61(96)81-48(31-41-34-73-35-75-41)60(95)80-46(28-37-11-5-3-6-12-37)59(94)77-45(15-9-25-74-66(71)72)64(99)84-26-10-16-51(84)63(98)82-49(32-53(69)88)58(93)76-36/h3-8,11-14,17-24,34-36,44-52,86-87H,9-10,15-16,25-33,68H2,1-2H3,(H2,69,88)(H2,70,90)(H,73,75)(H,76,93)(H,77,94)(H,78,91)(H,79,92)(H,80,95)(H,81,96)(H,82,98)(H,83,97)(H,100,101)(H4,71,72,74)/t36-,44-,45-,46+,47-,48-,49-,50-,51-,52-,67?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.20E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-4 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50410400
(CHEMBL2096818)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2cccc3ccccc23)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C77H89N19O16/c1-41-66(102)89-56(31-42-12-4-3-5-13-42)74(110)95-77(2,75(111)112)96(62(65(80)101)32-44-23-27-50(98)28-24-44)64(100)37-61(90-67(103)53(78)30-43-21-25-49(97)26-22-43)73(109)93-59(35-48-39-83-40-86-48)72(108)92-57(33-46-16-10-15-45-14-6-7-17-51(45)46)70(106)88-55(20-11-29-84-76(81)82)68(104)91-58(34-47-38-85-54-19-9-8-18-52(47)54)71(107)94-60(36-63(79)99)69(105)87-41/h3-10,12-19,21-28,38-41,53,55-62,85,97-98H,11,20,29-37,78H2,1-2H3,(H2,79,99)(H2,80,101)(H,83,86)(H,87,105)(H,88,106)(H,89,102)(H,90,103)(H,91,104)(H,92,108)(H,93,109)(H,94,107)(H,95,110)(H,111,112)(H4,81,82,84)/t41-,53-,55-,56-,57+,58-,59-,60-,61-,62-,77?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 9.20 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-1 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50410195
(CHEMBL2096710)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C64H79N15O13S2/c1-36-55(84)74-47(30-37-12-5-2-6-13-37)61(90)79-52(63(92)73-46(54(67)83)29-41-21-25-43(81)26-22-41)35-94-93-34-51(78-56(85)44(65)28-40-19-23-42(80)24-20-40)62(91)72-45(18-11-27-70-64(68)69)57(86)75-48(31-38-14-7-3-8-15-38)59(88)76-49(32-39-16-9-4-10-17-39)60(89)77-50(33-53(66)82)58(87)71-36/h2-10,12-17,19-26,36,44-52,80-81H,11,18,27-35,65H2,1H3,(H2,66,82)(H2,67,83)(H,71,87)(H,72,91)(H,73,92)(H,74,84)(H,75,86)(H,76,88)(H,77,89)(H,78,85)(H,79,90)(H4,68,69,70)/t36-,44-,45-,46-,47-,48-,49-,50-,51-,52-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-5 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50410413
(CHEMBL2096730)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C72H82N16O16/c1-39-62(94)80-51(29-40-12-5-3-6-13-40)68(100)86-72(2,71(103)104)88(58(61(75)93)31-43-21-25-47(90)26-22-43)60(92)35-55(81-63(95)49(73)28-42-19-23-46(89)24-20-42)67(99)82-53(33-45-37-76-38-78-45)66(98)85-56(30-41-14-7-4-8-15-41)70(102)87-27-11-18-57(87)69(101)84-52(32-44-36-77-50-17-10-9-16-48(44)50)65(97)83-54(34-59(74)91)64(96)79-39/h3-10,12-17,19-26,36-39,49,51-58,77,89-90H,11,18,27-35,73H2,1-2H3,(H2,74,91)(H2,75,93)(H,76,78)(H,79,96)(H,80,94)(H,81,95)(H,82,99)(H,83,97)(H,84,101)(H,85,98)(H,86,100)(H,103,104)/t39-,49-,51-,52-,53-,54-,55-,56+,57-,58-,72?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.73E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-3 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50410410
(CHEMBL2096742 | SHU-9119)Show SMILES CCCC[C@@H](NC(C)=O)C(=O)N[C@@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O Show InChI InChI=1S/C54H71N15O9/c1-3-4-15-40(63-31(2)70)48(73)69-45-27-46(71)59-21-10-9-17-39(47(55)72)64-51(76)43(25-35-28-61-38-16-8-7-14-37(35)38)67-49(74)41(18-11-22-60-54(56)57)65-50(75)42(24-32-19-20-33-12-5-6-13-34(33)23-32)66-52(77)44(68-53(45)78)26-36-29-58-30-62-36/h5-8,12-14,16,19-20,23,28-30,39-45,61H,3-4,9-11,15,17-18,21-22,24-27H2,1-2H3,(H2,55,72)(H,58,62)(H,59,71)(H,63,70)(H,64,76)(H,65,75)(H,66,77)(H,67,74)(H,68,78)(H,69,73)(H4,56,57,60)/t39-,40+,41-,42+,43-,44-,45+/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.31 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-5 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50410405
(CHEMBL2096726)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C69H85N19O16/c1-36-58(94)81-48(27-37-10-4-3-5-11-37)64(100)86-69(2,67(103)104)88(54(57(72)93)28-39-18-22-43(90)23-19-39)56(92)32-51(82-59(95)45(70)26-38-16-20-42(89)21-17-38)63(99)85-52(30-41-34-75-35-78-41)66(102)87-25-9-15-53(87)65(101)80-47(14-8-24-76-68(73)74)60(96)83-49(29-40-33-77-46-13-7-6-12-44(40)46)62(98)84-50(31-55(71)91)61(97)79-36/h3-7,10-13,16-23,33-36,45,47-54,77,89-90H,8-9,14-15,24-32,70H2,1-2H3,(H2,71,91)(H2,72,93)(H,75,78)(H,79,97)(H,80,101)(H,81,94)(H,82,95)(H,83,96)(H,84,98)(H,85,99)(H,86,100)(H,103,104)(H4,73,74,76)/t36-,45-,47-,48-,49-,50-,51-,52-,53-,54-,69?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.67E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-4 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50410415
(CHEMBL2096722)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C67H83N19O16/c1-34-56(92)79-46(14-9-23-74-66(71)72)59(95)82-48(27-39-31-75-45-13-8-7-12-43(39)45)62(98)84-50(29-53(69)89)61(97)78-35(2)57(93)80-47(25-36-10-5-4-6-11-36)64(100)85-67(3,65(101)102)86(52(55(70)91)26-38-17-21-42(88)22-18-38)54(90)30-51(81-58(94)44(68)24-37-15-19-41(87)20-16-37)63(99)83-49(60(96)77-34)28-40-32-73-33-76-40/h4-8,10-13,15-22,31-35,44,46-52,75,87-88H,9,14,23-30,68H2,1-3H3,(H2,69,89)(H2,70,91)(H,73,76)(H,77,96)(H,78,97)(H,79,92)(H,80,93)(H,81,94)(H,82,95)(H,83,99)(H,84,98)(H,85,100)(H,101,102)(H4,71,72,74)/t34-,35-,44-,46-,47-,48-,49-,50-,51-,52-,67?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.47E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-4 receptor at 100 uM |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50121900
(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)Show SMILES CCCC[C@H](NC(=O)C(CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C(C)C)C(N)=O Show InChI InChI=1S/C78H111N21O19/c1-5-6-19-52(91-75(116)61(41-101)97-72(113)57(34-46-24-26-49(103)27-25-46)94-74(115)60(40-100)88-44(4)102)68(109)92-54(28-29-64(105)106)70(111)96-59(36-48-38-83-42-87-48)73(114)93-56(33-45-16-8-7-9-17-45)71(112)90-53(22-14-31-84-78(81)82)69(110)95-58(35-47-37-85-51-20-11-10-18-50(47)51)67(108)86-39-63(104)89-55(21-12-13-30-79)77(118)99-32-15-23-62(99)76(117)98-65(43(2)3)66(80)107/h7-11,16-18,20,24-27,37-38,42-43,52-62,65,85,100-101,103H,5-6,12-15,19,21-23,28-36,39-41,79H2,1-4H3,(H2,80,107)(H,83,87)(H,86,108)(H,88,102)(H,89,104)(H,90,112)(H,91,116)(H,92,109)(H,93,114)(H,94,115)(H,95,110)(H,96,111)(H,97,113)(H,98,117)(H,105,106)(H4,81,82,84)/t52-,53-,54-,55-,56+,57-,58-,59-,60-,61?,62+,65+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0890 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-3 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50410394
(CHEMBL2096719)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2ccc(cc2)-c2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C77H90N18O16/c1-43-66(101)88-58(35-45-15-8-4-9-16-45)74(109)94-77(2,75(110)111)95(62(65(80)100)37-48-24-30-53(97)31-25-48)64(99)40-61(89-67(102)54(78)33-46-22-28-52(96)29-23-46)73(108)92-59(38-51-41-83-42-85-51)72(107)91-56(34-44-13-6-3-7-14-44)70(105)87-55(19-12-32-84-76(81)82)68(103)90-57(71(106)93-60(39-63(79)98)69(104)86-43)36-47-20-26-50(27-21-47)49-17-10-5-11-18-49/h3-11,13-18,20-31,41-43,54-62,96-97H,12,19,32-40,78H2,1-2H3,(H2,79,98)(H2,80,100)(H,83,85)(H,86,104)(H,87,105)(H,88,101)(H,89,102)(H,90,103)(H,91,107)(H,92,108)(H,93,106)(H,94,109)(H,110,111)(H4,81,82,84)/t43-,54-,55-,56+,57-,58-,59-,60-,61-,62-,77?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 450 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-3 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50410396
(CHEMBL2096716)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C67H84N18O16/c1-36-56(91)78-47(29-38-13-7-4-8-14-38)62(97)83-67(2,65(100)101)85(52(55(70)90)30-40-19-23-43(87)24-20-40)54(89)33-50(79-57(92)44(68)27-39-17-21-42(86)22-18-39)61(96)81-48(31-41-34-73-35-75-41)60(95)80-46(28-37-11-5-3-6-12-37)59(94)77-45(15-9-25-74-66(71)72)64(99)84-26-10-16-51(84)63(98)82-49(32-53(69)88)58(93)76-36/h3-8,11-14,17-24,34-36,44-52,86-87H,9-10,15-16,25-33,68H2,1-2H3,(H2,69,88)(H2,70,90)(H,73,75)(H,76,93)(H,77,94)(H,78,91)(H,79,92)(H,80,95)(H,81,96)(H,82,98)(H,83,97)(H,100,101)(H4,71,72,74)/t36-,44-,45-,46+,47-,48-,49-,50-,51-,52-,67?/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 700 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-5 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50410408
(CHEMBL2096713)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C73H87N19O16/c1-39-62(98)85-53(30-41-14-7-4-8-15-41)70(106)91-73(2,71(107)108)92(58(61(76)97)31-43-21-25-47(94)26-22-43)60(96)35-57(86-63(99)49(74)28-42-19-23-46(93)24-20-42)69(105)89-55(33-45-37-79-38-82-45)68(104)87-52(29-40-12-5-3-6-13-40)66(102)84-51(18-11-27-80-72(77)78)64(100)88-54(32-44-36-81-50-17-10-9-16-48(44)50)67(103)90-56(34-59(75)95)65(101)83-39/h3-10,12-17,19-26,36-39,49,51-58,81,93-94H,11,18,27-35,74H2,1-2H3,(H2,75,95)(H2,76,97)(H,79,82)(H,83,101)(H,84,102)(H,85,98)(H,86,99)(H,87,104)(H,88,100)(H,89,105)(H,90,103)(H,91,106)(H,107,108)(H4,77,78,80)/t39-,49-,51-,52+,53-,54-,55-,56-,57-,58-,73?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.970 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-3 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50410396
(CHEMBL2096716)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C67H84N18O16/c1-36-56(91)78-47(29-38-13-7-4-8-14-38)62(97)83-67(2,65(100)101)85(52(55(70)90)30-40-19-23-43(87)24-20-40)54(89)33-50(79-57(92)44(68)27-39-17-21-42(86)22-18-39)61(96)81-48(31-41-34-73-35-75-41)60(95)80-46(28-37-11-5-3-6-12-37)59(94)77-45(15-9-25-74-66(71)72)64(99)84-26-10-16-51(84)63(98)82-49(32-53(69)88)58(93)76-36/h3-8,11-14,17-24,34-36,44-52,86-87H,9-10,15-16,25-33,68H2,1-2H3,(H2,69,88)(H2,70,90)(H,73,75)(H,76,93)(H,77,94)(H,78,91)(H,79,92)(H,80,95)(H,81,96)(H,82,98)(H,83,97)(H,100,101)(H4,71,72,74)/t36-,44-,45-,46+,47-,48-,49-,50-,51-,52-,67?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.92E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-3 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50410397
(CHEMBL2096718)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C75H88N18O16/c1-41-64(99)86-56(33-43-14-7-4-8-15-43)72(107)92-75(2,73(108)109)93(60(63(78)98)35-45-22-27-51(95)28-23-45)62(97)38-59(87-65(100)52(76)31-44-20-25-50(94)26-21-44)71(106)90-57(36-49-39-81-40-83-49)70(105)89-54(32-42-12-5-3-6-13-42)68(103)85-53(18-11-29-82-74(79)80)66(101)88-55(69(104)91-58(37-61(77)96)67(102)84-41)34-46-19-24-47-16-9-10-17-48(47)30-46/h3-10,12-17,19-28,30,39-41,52-60,94-95H,11,18,29,31-38,76H2,1-2H3,(H2,77,96)(H2,78,98)(H,81,83)(H,84,102)(H,85,103)(H,86,99)(H,87,100)(H,88,101)(H,89,105)(H,90,106)(H,91,104)(H,92,107)(H,108,109)(H4,79,80,82)/t41-,52-,53-,54+,55+,56-,57-,58-,59-,60-,75?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.670 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-4 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50410404
(CHEMBL2096720)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C72H86N18O16/c1-39-61(96)83-52(30-41-14-7-4-8-15-41)67(102)88-72(2,70(105)106)90(56(60(75)95)31-43-21-25-48(92)26-22-43)59(94)35-55(84-62(97)49(73)28-42-19-23-47(91)24-20-42)66(101)86-53(33-46-36-78-38-80-46)65(100)85-51(29-40-12-5-3-6-13-40)64(99)82-50(18-11-27-79-71(76)77)69(104)89-37-45-17-10-9-16-44(45)32-57(89)68(103)87-54(34-58(74)93)63(98)81-39/h3-10,12-17,19-26,36,38-39,49-57,91-92H,11,18,27-35,37,73H2,1-2H3,(H2,74,93)(H2,75,95)(H,78,80)(H,81,98)(H,82,99)(H,83,96)(H,84,97)(H,85,100)(H,86,101)(H,87,103)(H,88,102)(H,105,106)(H4,76,77,79)/t39-,49-,50-,51+,52-,53-,54-,55-,56-,57-,72?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 260 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-4 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50410411
(CHEMBL2096728)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C77H89N19O16/c1-41-66(102)89-57(31-42-11-4-3-5-12-42)74(110)95-77(2,75(111)112)96(62(65(80)101)33-44-21-26-51(98)27-22-44)64(100)37-61(90-67(103)53(78)30-43-19-24-50(97)25-20-43)73(109)93-59(35-49-39-83-40-86-49)72(108)91-56(32-45-18-23-46-13-6-7-14-47(46)29-45)70(106)88-55(17-10-28-84-76(81)82)68(104)92-58(34-48-38-85-54-16-9-8-15-52(48)54)71(107)94-60(36-63(79)99)69(105)87-41/h3-9,11-16,18-27,29,38-41,53,55-62,85,97-98H,10,17,28,30-37,78H2,1-2H3,(H2,79,99)(H2,80,101)(H,83,86)(H,87,105)(H,88,106)(H,89,102)(H,90,103)(H,91,108)(H,92,104)(H,93,109)(H,94,107)(H,95,110)(H,111,112)(H4,81,82,84)/t41-,53-,55-,56+,57-,58-,59-,60-,61-,62-,77?/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 22.3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-5 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50410393
(CHEMBL2096819)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C73H87N19O16/c1-39-62(98)85-53(30-41-14-7-4-8-15-41)70(106)91-73(2,71(107)108)92(58(61(76)97)31-43-21-25-47(94)26-22-43)60(96)35-57(86-63(99)49(74)28-42-19-23-46(93)24-20-42)69(105)89-55(33-45-37-79-38-82-45)68(104)87-52(29-40-12-5-3-6-13-40)66(102)84-51(18-11-27-80-72(77)78)64(100)88-54(32-44-36-81-50-17-10-9-16-48(44)50)67(103)90-56(34-59(75)95)65(101)83-39/h3-10,12-17,19-26,36-39,49,51-58,81,93-94H,11,18,27-35,74H2,1-2H3,(H2,75,95)(H2,76,97)(H,79,82)(H,83,101)(H,84,102)(H,85,98)(H,86,99)(H,87,104)(H,88,100)(H,89,105)(H,90,103)(H,91,106)(H,107,108)(H4,77,78,80)/t39-,49-,51-,52+,53+,54-,55-,56-,57-,58-,73?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.660 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-4 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50410400
(CHEMBL2096818)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2cccc3ccccc23)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C77H89N19O16/c1-41-66(102)89-56(31-42-12-4-3-5-13-42)74(110)95-77(2,75(111)112)96(62(65(80)101)32-44-23-27-50(98)28-24-44)64(100)37-61(90-67(103)53(78)30-43-21-25-49(97)26-22-43)73(109)93-59(35-48-39-83-40-86-48)72(108)92-57(33-46-16-10-15-45-14-6-7-17-51(45)46)70(106)88-55(20-11-29-84-76(81)82)68(104)91-58(34-47-38-85-54-19-9-8-18-52(47)54)71(107)94-60(36-63(79)99)69(105)87-41/h3-10,12-19,21-28,38-41,53,55-62,85,97-98H,11,20,29-37,78H2,1-2H3,(H2,79,99)(H2,80,101)(H,83,86)(H,87,105)(H,88,106)(H,89,102)(H,90,103)(H,91,104)(H,92,108)(H,93,109)(H,94,107)(H,95,110)(H,111,112)(H4,81,82,84)/t41-,53-,55-,56-,57+,58-,59-,60-,61-,62-,77?/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.13 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-5 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50410406
(CHEMBL2096723)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C70H80N16O16/c1-37-60(92)79-51(28-40-14-8-5-9-15-40)68(100)85-70(3,69(101)102)86(56(59(73)91)29-42-20-24-46(88)25-21-42)58(90)33-55(81-62(94)48(71)26-41-18-22-45(87)23-19-41)67(99)83-53(31-44-35-74-36-76-44)66(98)82-50(27-39-12-6-4-7-13-39)63(95)77-38(2)61(93)80-52(30-43-34-75-49-17-11-10-16-47(43)49)65(97)84-54(32-57(72)89)64(96)78-37/h4-25,34-38,48,50-56,75,87-88H,26-33,71H2,1-3H3,(H2,72,89)(H2,73,91)(H,74,76)(H,77,95)(H,78,96)(H,79,92)(H,80,93)(H,81,94)(H,82,98)(H,83,99)(H,84,97)(H,85,100)(H,101,102)/t37-,38-,48-,50+,51-,52-,53-,54-,55-,56-,70?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.38E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-3 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50410393
(CHEMBL2096819)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C73H87N19O16/c1-39-62(98)85-53(30-41-14-7-4-8-15-41)70(106)91-73(2,71(107)108)92(58(61(76)97)31-43-21-25-47(94)26-22-43)60(96)35-57(86-63(99)49(74)28-42-19-23-46(93)24-20-42)69(105)89-55(33-45-37-79-38-82-45)68(104)87-52(29-40-12-5-3-6-13-40)66(102)84-51(18-11-27-80-72(77)78)64(100)88-54(32-44-36-81-50-17-10-9-16-48(44)50)67(103)90-56(34-59(75)95)65(101)83-39/h3-10,12-17,19-26,36-39,49,51-58,81,93-94H,11,18,27-35,74H2,1-2H3,(H2,75,95)(H2,76,97)(H,79,82)(H,83,101)(H,84,102)(H,85,98)(H,86,99)(H,87,104)(H,88,100)(H,89,105)(H,90,103)(H,91,106)(H,107,108)(H4,77,78,80)/t39-,49-,51-,52+,53+,54-,55-,56-,57-,58-,73?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.61 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-1 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50410395
(CHEMBL2096731)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C73H87N17O16/c1-40-63(96)83-54(31-42-15-7-4-8-16-42)71(104)89-73(2,72(105)106)90(59(62(77)95)32-44-22-26-48(92)27-23-44)61(94)36-58(84-64(97)50(75)29-43-20-24-47(91)25-21-43)70(103)87-56(34-46-38-78-39-80-46)69(102)85-53(30-41-13-5-3-6-14-41)67(100)82-52(19-11-12-28-74)65(98)86-55(33-45-37-79-51-18-10-9-17-49(45)51)68(101)88-57(35-60(76)93)66(99)81-40/h3-10,13-18,20-27,37-40,50,52-59,79,91-92H,11-12,19,28-36,74-75H2,1-2H3,(H2,76,93)(H2,77,95)(H,78,80)(H,81,99)(H,82,100)(H,83,96)(H,84,97)(H,85,102)(H,86,98)(H,87,103)(H,88,101)(H,89,104)(H,105,106)/t40-,50-,52-,53+,54-,55-,56-,57-,58-,59-,73?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 8.60E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-4 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50410195
(CHEMBL2096710)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C64H79N15O13S2/c1-36-55(84)74-47(30-37-12-5-2-6-13-37)61(90)79-52(63(92)73-46(54(67)83)29-41-21-25-43(81)26-22-41)35-94-93-34-51(78-56(85)44(65)28-40-19-23-42(80)24-20-40)62(91)72-45(18-11-27-70-64(68)69)57(86)75-48(31-38-14-7-3-8-15-38)59(88)76-49(32-39-16-9-4-10-17-39)60(89)77-50(33-53(66)82)58(87)71-36/h2-10,12-17,19-26,36,44-52,80-81H,11,18,27-35,65H2,1H3,(H2,66,82)(H2,67,83)(H,71,87)(H,72,91)(H,73,92)(H,74,84)(H,75,86)(H,76,88)(H,77,89)(H,78,85)(H,79,90)(H4,68,69,70)/t36-,44-,45-,46-,47-,48-,49-,50-,51-,52-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-3 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50410403
(CHEMBL2096717)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C75H88N18O16/c1-41-64(99)86-56(33-43-14-7-4-8-15-43)72(107)92-75(2,73(108)109)93(60(63(78)98)35-45-22-27-51(95)28-23-45)62(97)38-59(87-65(100)52(76)31-44-20-25-50(94)26-21-44)71(106)90-57(36-49-39-81-40-83-49)70(105)89-54(32-42-12-5-3-6-13-42)68(103)85-53(18-11-29-82-74(79)80)66(101)88-55(69(104)91-58(37-61(77)96)67(102)84-41)34-46-19-24-47-16-9-10-17-48(47)30-46/h3-10,12-17,19-28,30,39-41,52-60,94-95H,11,18,29,31-38,76H2,1-2H3,(H2,77,96)(H2,78,98)(H,81,83)(H,84,102)(H,85,103)(H,86,99)(H,87,100)(H,88,101)(H,89,105)(H,90,106)(H,91,104)(H,92,107)(H,108,109)(H4,79,80,82)/t41-,52-,53-,54+,55-,56-,57-,58-,59-,60-,75?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 5.56 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-3 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50410400
(CHEMBL2096818)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2cccc3ccccc23)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C77H89N19O16/c1-41-66(102)89-56(31-42-12-4-3-5-13-42)74(110)95-77(2,75(111)112)96(62(65(80)101)32-44-23-27-50(98)28-24-44)64(100)37-61(90-67(103)53(78)30-43-21-25-49(97)26-22-43)73(109)93-59(35-48-39-83-40-86-48)72(108)92-57(33-46-16-10-15-45-14-6-7-17-51(45)46)70(106)88-55(20-11-29-84-76(81)82)68(104)91-58(34-47-38-85-54-19-9-8-18-52(47)54)71(107)94-60(36-63(79)99)69(105)87-41/h3-10,12-19,21-28,38-41,53,55-62,85,97-98H,11,20,29-37,78H2,1-2H3,(H2,79,99)(H2,80,101)(H,83,86)(H,87,105)(H,88,106)(H,89,102)(H,90,103)(H,91,104)(H,92,108)(H,93,109)(H,94,107)(H,95,110)(H,111,112)(H4,81,82,84)/t41-,53-,55-,56-,57+,58-,59-,60-,61-,62-,77?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.570 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-4 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50410401
(CHEMBL2096729)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccc(cc2)-c2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C79H91N19O16/c1-43-68(104)91-59(33-44-12-5-3-6-13-44)76(112)97-79(2,77(113)114)98(64(67(82)103)35-47-23-29-53(100)30-24-47)66(102)39-63(92-69(105)55(80)32-45-21-27-52(99)28-22-45)75(111)95-61(37-51-41-85-42-88-51)74(110)93-58(34-46-19-25-49(26-20-46)48-14-7-4-8-15-48)72(108)90-57(18-11-31-86-78(83)84)70(106)94-60(36-50-40-87-56-17-10-9-16-54(50)56)73(109)96-62(38-65(81)101)71(107)89-43/h3-10,12-17,19-30,40-43,55,57-64,87,99-100H,11,18,31-39,80H2,1-2H3,(H2,81,101)(H2,82,103)(H,85,88)(H,89,107)(H,90,108)(H,91,104)(H,92,105)(H,93,110)(H,94,106)(H,95,111)(H,96,109)(H,97,112)(H,113,114)(H4,83,84,86)/t43-,55-,57-,58+,59-,60-,61-,62-,63-,64-,79?/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 5.27 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-5 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50410407
(CHEMBL2096715)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)C2(CCc3ccccc3C2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C78H91N17O16/c1-43-66(101)88-58(36-45-16-7-4-8-17-45)72(107)93-77(2,75(110)111)95(62(65(81)100)37-47-25-29-52(97)30-26-47)64(99)40-61(89-67(102)54(79)34-46-23-27-51(96)28-24-46)73(108)94-78(32-31-48-18-9-10-19-49(48)41-78)74(109)92-57(35-44-14-5-3-6-15-44)70(105)87-56(22-13-33-84-76(82)83)68(103)90-59(38-50-42-85-55-21-12-11-20-53(50)55)71(106)91-60(39-63(80)98)69(104)86-43/h3-12,14-21,23-30,42-43,54,56-62,85,96-97H,13,22,31-41,79H2,1-2H3,(H2,80,98)(H2,81,100)(H,86,104)(H,87,105)(H,88,101)(H,89,102)(H,90,103)(H,91,106)(H,92,109)(H,93,107)(H,94,108)(H,110,111)(H4,82,83,84)/t43-,54-,56-,57+,58-,59-,60-,61-,62-,77?,78?/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 440 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-5 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50410413
(CHEMBL2096730)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C72H82N16O16/c1-39-62(94)80-51(29-40-12-5-3-6-13-40)68(100)86-72(2,71(103)104)88(58(61(75)93)31-43-21-25-47(90)26-22-43)60(92)35-55(81-63(95)49(73)28-42-19-23-46(89)24-20-42)67(99)82-53(33-45-37-76-38-78-45)66(98)85-56(30-41-14-7-4-8-15-41)70(102)87-27-11-18-57(87)69(101)84-52(32-44-36-77-50-17-10-9-16-48(44)50)65(97)83-54(34-59(74)91)64(96)79-39/h3-10,12-17,19-26,36-39,49,51-58,77,89-90H,11,18,27-35,73H2,1-2H3,(H2,74,91)(H2,75,93)(H,76,78)(H,79,96)(H,80,94)(H,81,95)(H,82,99)(H,83,97)(H,84,101)(H,85,98)(H,86,100)(H,103,104)/t39-,49-,51-,52-,53-,54-,55-,56+,57-,58-,72?/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-5 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50410406
(CHEMBL2096723)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C70H80N16O16/c1-37-60(92)79-51(28-40-14-8-5-9-15-40)68(100)85-70(3,69(101)102)86(56(59(73)91)29-42-20-24-46(88)25-21-42)58(90)33-55(81-62(94)48(71)26-41-18-22-45(87)23-19-41)67(99)83-53(31-44-35-74-36-76-44)66(98)82-50(27-39-12-6-4-7-13-39)63(95)77-38(2)61(93)80-52(30-43-34-75-49-17-11-10-16-47(43)49)65(97)84-54(32-57(72)89)64(96)78-37/h4-25,34-38,48,50-56,75,87-88H,26-33,71H2,1-3H3,(H2,72,89)(H2,73,91)(H,74,76)(H,77,95)(H,78,96)(H,79,92)(H,80,93)(H,81,94)(H,82,98)(H,83,99)(H,84,97)(H,85,100)(H,101,102)/t37-,38-,48-,50+,51-,52-,53-,54-,55-,56-,70?/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.06 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-5 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50410415
(CHEMBL2096722)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C67H83N19O16/c1-34-56(92)79-46(14-9-23-74-66(71)72)59(95)82-48(27-39-31-75-45-13-8-7-12-43(39)45)62(98)84-50(29-53(69)89)61(97)78-35(2)57(93)80-47(25-36-10-5-4-6-11-36)64(100)85-67(3,65(101)102)86(52(55(70)91)26-38-17-21-42(88)22-18-38)54(90)30-51(81-58(94)44(68)24-37-15-19-41(87)20-16-37)63(99)83-49(60(96)77-34)28-40-32-73-33-76-40/h4-8,10-13,15-22,31-35,44,46-52,75,87-88H,9,14,23-30,68H2,1-3H3,(H2,69,89)(H2,70,91)(H,73,76)(H,77,96)(H,78,97)(H,79,92)(H,80,93)(H,81,94)(H,82,95)(H,83,99)(H,84,98)(H,85,100)(H,101,102)(H4,71,72,74)/t34-,35-,44-,46-,47-,48-,49-,50-,51-,52-,67?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-1 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50410195
(CHEMBL2096710)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C64H79N15O13S2/c1-36-55(84)74-47(30-37-12-5-2-6-13-37)61(90)79-52(63(92)73-46(54(67)83)29-41-21-25-43(81)26-22-41)35-94-93-34-51(78-56(85)44(65)28-40-19-23-42(80)24-20-40)62(91)72-45(18-11-27-70-64(68)69)57(86)75-48(31-38-14-7-3-8-15-38)59(88)76-49(32-39-16-9-4-10-17-39)60(89)77-50(33-53(66)82)58(87)71-36/h2-10,12-17,19-26,36,44-52,80-81H,11,18,27-35,65H2,1H3,(H2,66,82)(H2,67,83)(H,71,87)(H,72,91)(H,73,92)(H,74,84)(H,75,86)(H,76,88)(H,77,89)(H,78,85)(H,79,90)(H4,68,69,70)/t36-,44-,45-,46-,47-,48-,49-,50-,51-,52-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 5.12E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-1 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50410412
(CHEMBL2096725)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C72H87N17O16/c1-39-61(95)82-52(33-41-15-7-4-8-16-41)67(101)87-72(2,70(104)105)89(57(60(75)94)34-43-23-27-46(91)28-24-43)59(93)37-55(86-62(96)48(73)31-42-21-25-45(90)26-22-42)69(103)88-30-12-20-56(88)68(102)85-51(32-40-13-5-3-6-14-40)65(99)81-50(19-11-29-78-71(76)77)63(97)83-53(35-44-38-79-49-18-10-9-17-47(44)49)66(100)84-54(36-58(74)92)64(98)80-39/h3-10,13-18,21-28,38-39,48,50-57,79,90-91H,11-12,19-20,29-37,73H2,1-2H3,(H2,74,92)(H2,75,94)(H,80,98)(H,81,99)(H,82,95)(H,83,97)(H,84,100)(H,85,102)(H,86,96)(H,87,101)(H,104,105)(H4,76,77,78)/t39-,48-,50-,51+,52-,53-,54-,55-,56-,57-,72?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 22.1 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-1 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50410401
(CHEMBL2096729)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccc(cc2)-c2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C79H91N19O16/c1-43-68(104)91-59(33-44-12-5-3-6-13-44)76(112)97-79(2,77(113)114)98(64(67(82)103)35-47-23-29-53(100)30-24-47)66(102)39-63(92-69(105)55(80)32-45-21-27-52(99)28-22-45)75(111)95-61(37-51-41-85-42-88-51)74(110)93-58(34-46-19-25-49(26-20-46)48-14-7-4-8-15-48)72(108)90-57(18-11-31-86-78(83)84)70(106)94-60(36-50-40-87-56-17-10-9-16-54(50)56)73(109)96-62(38-65(81)101)71(107)89-43/h3-10,12-17,19-30,40-43,55,57-64,87,99-100H,11,18,31-39,80H2,1-2H3,(H2,81,101)(H2,82,103)(H,85,88)(H,89,107)(H,90,108)(H,91,104)(H,92,105)(H,93,110)(H,94,106)(H,95,111)(H,96,109)(H,97,112)(H,113,114)(H4,83,84,86)/t43-,55-,57-,58+,59-,60-,61-,62-,63-,64-,79?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.570 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-4 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50029747
((4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S...)Show SMILES CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O Show InChI InChI=1S/C77H109N21O19S/c1-42(2)64(65(79)106)97-75(116)61-20-13-30-98(61)76(117)54(18-10-11-28-78)88-62(103)38-85-66(107)57(34-46-36-84-50-17-9-8-16-49(46)50)94-67(108)51(19-12-29-83-77(80)81)89-70(111)55(32-44-14-6-5-7-15-44)92-72(113)58(35-47-37-82-41-86-47)95-68(109)52(25-26-63(104)105)90-69(110)53(27-31-118-4)91-74(115)60(40-100)96-71(112)56(33-45-21-23-48(102)24-22-45)93-73(114)59(39-99)87-43(3)101/h5-9,14-17,21-24,36-37,41-42,51-61,64,84,99-100,102H,10-13,18-20,25-35,38-40,78H2,1-4H3,(H2,79,106)(H,82,86)(H,85,107)(H,87,101)(H,88,103)(H,89,111)(H,90,110)(H,91,115)(H,92,113)(H,93,114)(H,94,108)(H,95,109)(H,96,112)(H,97,116)(H,104,105)(H4,80,81,83)/t51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,64-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.320 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-5 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50410397
(CHEMBL2096718)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C75H88N18O16/c1-41-64(99)86-56(33-43-14-7-4-8-15-43)72(107)92-75(2,73(108)109)93(60(63(78)98)35-45-22-27-51(95)28-23-45)62(97)38-59(87-65(100)52(76)31-44-20-25-50(94)26-21-44)71(106)90-57(36-49-39-81-40-83-49)70(105)89-54(32-42-12-5-3-6-13-42)68(103)85-53(18-11-29-82-74(79)80)66(101)88-55(69(104)91-58(37-61(77)96)67(102)84-41)34-46-19-24-47-16-9-10-17-48(47)30-46/h3-10,12-17,19-28,30,39-41,52-60,94-95H,11,18,29,31-38,76H2,1-2H3,(H2,77,96)(H2,78,98)(H,81,83)(H,84,102)(H,85,103)(H,86,99)(H,87,100)(H,88,101)(H,89,105)(H,90,106)(H,91,104)(H,92,107)(H,108,109)(H4,79,80,82)/t41-,52-,53-,54+,55+,56-,57-,58-,59-,60-,75?/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.950 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-5 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50410399
(CHEMBL2096712)Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O Show InChI InChI=1S/C50H69N15O9/c1-3-4-16-35(58-29(2)66)43(68)64-41-25-42(67)65-45(70)36(18-10-11-20-51)59-47(72)39(23-31-26-56-34-17-9-8-15-33(31)34)62-44(69)37(19-12-21-55-50(52)53)60-46(71)38(22-30-13-6-5-7-14-30)61-48(73)40(63-49(41)74)24-32-27-54-28-57-32/h5-9,13-15,17,26-28,35-41,56H,3-4,10-12,16,18-25,51H2,1-2H3,(H,54,57)(H,58,66)(H,59,72)(H,60,71)(H,61,73)(H,62,69)(H,63,74)(H,64,68)(H4,52,53,55)(H,65,67,70)/t35-,36-,37-,38+,39-,40-,41-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.0220 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-1 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50410397
(CHEMBL2096718)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C75H88N18O16/c1-41-64(99)86-56(33-43-14-7-4-8-15-43)72(107)92-75(2,73(108)109)93(60(63(78)98)35-45-22-27-51(95)28-23-45)62(97)38-59(87-65(100)52(76)31-44-20-25-50(94)26-21-44)71(106)90-57(36-49-39-81-40-83-49)70(105)89-54(32-42-12-5-3-6-13-42)68(103)85-53(18-11-29-82-74(79)80)66(101)88-55(69(104)91-58(37-61(77)96)67(102)84-41)34-46-19-24-47-16-9-10-17-48(47)30-46/h3-10,12-17,19-28,30,39-41,52-60,94-95H,11,18,29,31-38,76H2,1-2H3,(H2,77,96)(H2,78,98)(H,81,83)(H,84,102)(H,85,103)(H,86,99)(H,87,100)(H,88,101)(H,89,105)(H,90,106)(H,91,104)(H,92,107)(H,108,109)(H4,79,80,82)/t41-,52-,53-,54+,55+,56-,57-,58-,59-,60-,75?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-1 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50410409
(CHEMBL2096727)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccc(I)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C73H86IN19O16/c1-38-62(99)86-53(28-39-9-4-3-5-10-39)70(107)92-73(2,71(108)109)93(58(61(77)98)30-42-18-24-47(95)25-19-42)60(97)34-57(87-63(100)49(75)27-40-16-22-46(94)23-17-40)69(106)90-55(32-45-36-80-37-83-45)68(105)88-52(29-41-14-20-44(74)21-15-41)66(103)85-51(13-8-26-81-72(78)79)64(101)89-54(31-43-35-82-50-12-7-6-11-48(43)50)67(104)91-56(33-59(76)96)65(102)84-38/h3-7,9-12,14-25,35-38,49,51-58,82,94-95H,8,13,26-34,75H2,1-2H3,(H2,76,96)(H2,77,98)(H,80,83)(H,84,102)(H,85,103)(H,86,99)(H,87,100)(H,88,105)(H,89,101)(H,90,106)(H,91,104)(H,92,107)(H,108,109)(H4,78,79,81)/t38-,49-,51-,52+,53-,54-,55-,56-,57-,58-,73?/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.33 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-5 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50410411
(CHEMBL2096728)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C77H89N19O16/c1-41-66(102)89-57(31-42-11-4-3-5-12-42)74(110)95-77(2,75(111)112)96(62(65(80)101)33-44-21-26-51(98)27-22-44)64(100)37-61(90-67(103)53(78)30-43-19-24-50(97)25-20-43)73(109)93-59(35-49-39-83-40-86-49)72(108)91-56(32-45-18-23-46-13-6-7-14-47(46)29-45)70(106)88-55(17-10-28-84-76(81)82)68(104)92-58(34-48-38-85-54-16-9-8-15-52(48)54)71(107)94-60(36-63(79)99)69(105)87-41/h3-9,11-16,18-27,29,38-41,53,55-62,85,97-98H,10,17,28,30-37,78H2,1-2H3,(H2,79,99)(H2,80,101)(H,83,86)(H,87,105)(H,88,106)(H,89,102)(H,90,103)(H,91,108)(H,92,104)(H,93,109)(H,94,107)(H,95,110)(H,111,112)(H4,81,82,84)/t41-,53-,55-,56+,57-,58-,59-,60-,61-,62-,77?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 5.56 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-1 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50410398
(CHEMBL2096721)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C70H85N17O16/c1-37-59(93)81-50(30-39-13-6-4-7-14-39)65(99)80-49(19-12-28-76-69(74)75)62(96)84-52(33-43-36-77-48-18-11-10-17-46(43)48)66(100)85-53(34-56(72)90)63(97)78-38(2)60(94)82-51(31-40-15-8-5-9-16-40)67(101)86-70(3,68(102)103)87(55(58(73)92)32-42-22-26-45(89)27-23-42)57(91)35-54(64(98)79-37)83-61(95)47(71)29-41-20-24-44(88)25-21-41/h4-11,13-18,20-27,36-38,47,49-55,77,88-89H,12,19,28-35,71H2,1-3H3,(H2,72,90)(H2,73,92)(H,78,97)(H,79,98)(H,80,99)(H,81,93)(H,82,94)(H,83,95)(H,84,96)(H,85,100)(H,86,101)(H,102,103)(H4,74,75,76)/t37-,38-,47-,49-,50+,51-,52-,53-,54-,55-,70?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.20 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-1 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50410412
(CHEMBL2096725)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C72H87N17O16/c1-39-61(95)82-52(33-41-15-7-4-8-16-41)67(101)87-72(2,70(104)105)89(57(60(75)94)34-43-23-27-46(91)28-24-43)59(93)37-55(86-62(96)48(73)31-42-21-25-45(90)26-22-42)69(103)88-30-12-20-56(88)68(102)85-51(32-40-13-5-3-6-14-40)65(99)81-50(19-11-29-78-71(76)77)63(97)83-53(35-44-38-79-49-18-10-9-17-47(44)49)66(100)84-54(36-58(74)92)64(98)80-39/h3-10,13-18,21-28,38-39,48,50-57,79,90-91H,11-12,19-20,29-37,73H2,1-2H3,(H2,74,92)(H2,75,94)(H,80,98)(H,81,99)(H,82,95)(H,83,97)(H,84,100)(H,85,102)(H,86,96)(H,87,101)(H,104,105)(H4,76,77,78)/t39-,48-,50-,51+,52-,53-,54-,55-,56-,57-,72?/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.16 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-5 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50410412
(CHEMBL2096725)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C72H87N17O16/c1-39-61(95)82-52(33-41-15-7-4-8-16-41)67(101)87-72(2,70(104)105)89(57(60(75)94)34-43-23-27-46(91)28-24-43)59(93)37-55(86-62(96)48(73)31-42-21-25-45(90)26-22-42)69(103)88-30-12-20-56(88)68(102)85-51(32-40-13-5-3-6-14-40)65(99)81-50(19-11-29-78-71(76)77)63(97)83-53(35-44-38-79-49-18-10-9-17-47(44)49)66(100)84-54(36-58(74)92)64(98)80-39/h3-10,13-18,21-28,38-39,48,50-57,79,90-91H,11-12,19-20,29-37,73H2,1-2H3,(H2,74,92)(H2,75,94)(H,80,98)(H,81,99)(H,82,95)(H,83,97)(H,84,100)(H,85,102)(H,86,96)(H,87,101)(H,104,105)(H4,76,77,78)/t39-,48-,50-,51+,52-,53-,54-,55-,56-,57-,72?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.630 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-4 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50410402
(CHEMBL2096724)Show SMILES C[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C65H82N18O16/c1-34-55(90)78-48(30-51(67)86)58(93)75-35(2)54(89)77-46(27-37-13-8-5-9-14-37)62(97)82-65(3,63(98)99)83(50(53(68)88)28-39-18-22-42(85)23-19-39)52(87)31-49(79-56(91)43(66)25-38-16-20-41(84)21-17-38)61(96)81-47(29-40-32-71-33-73-40)60(95)80-45(26-36-11-6-4-7-12-36)59(94)76-44(57(92)74-34)15-10-24-72-64(69)70/h4-9,11-14,16-23,32-35,43-50,84-85H,10,15,24-31,66H2,1-3H3,(H2,67,86)(H2,68,88)(H,71,73)(H,74,92)(H,75,93)(H,76,94)(H,77,89)(H,78,90)(H,79,91)(H,80,95)(H,81,96)(H,82,97)(H,98,99)(H4,69,70,72)/t34-,35-,43-,44-,45+,46-,47-,48-,49-,50-,65?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 350 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-1 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50410408
(CHEMBL2096713)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C73H87N19O16/c1-39-62(98)85-53(30-41-14-7-4-8-15-41)70(106)91-73(2,71(107)108)92(58(61(76)97)31-43-21-25-47(94)26-22-43)60(96)35-57(86-63(99)49(74)28-42-19-23-46(93)24-20-42)69(105)89-55(33-45-37-79-38-82-45)68(104)87-52(29-40-12-5-3-6-13-40)66(102)84-51(18-11-27-80-72(77)78)64(100)88-54(32-44-36-81-50-17-10-9-16-48(44)50)67(103)90-56(34-59(75)95)65(101)83-39/h3-10,12-17,19-26,36-39,49,51-58,81,93-94H,11,18,27-35,74H2,1-2H3,(H2,75,95)(H2,76,97)(H,79,82)(H,83,101)(H,84,102)(H,85,98)(H,86,99)(H,87,104)(H,88,100)(H,89,105)(H,90,103)(H,91,106)(H,107,108)(H4,77,78,80)/t39-,49-,51-,52+,53-,54-,55-,56-,57-,58-,73?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.220 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-1 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50410399
(CHEMBL2096712)Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O Show InChI InChI=1S/C50H69N15O9/c1-3-4-16-35(58-29(2)66)43(68)64-41-25-42(67)65-45(70)36(18-10-11-20-51)59-47(72)39(23-31-26-56-34-17-9-8-15-33(31)34)62-44(69)37(19-12-21-55-50(52)53)60-46(71)38(22-30-13-6-5-7-14-30)61-48(73)40(63-49(41)74)24-32-27-54-28-57-32/h5-9,13-15,17,26-28,35-41,56H,3-4,10-12,16,18-25,51H2,1-2H3,(H,54,57)(H,58,66)(H,59,72)(H,60,71)(H,61,73)(H,62,69)(H,63,74)(H,64,68)(H4,52,53,55)(H,65,67,70)/t35-,36-,37-,38+,39-,40-,41-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.130 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-3 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50410409
(CHEMBL2096727)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccc(I)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C73H86IN19O16/c1-38-62(99)86-53(28-39-9-4-3-5-10-39)70(107)92-73(2,71(108)109)93(58(61(77)98)30-42-18-24-47(95)25-19-42)60(97)34-57(87-63(100)49(75)27-40-16-22-46(94)23-17-40)69(106)90-55(32-45-36-80-37-83-45)68(105)88-52(29-41-14-20-44(74)21-15-41)66(103)85-51(13-8-26-81-72(78)79)64(101)89-54(31-43-35-82-50-12-7-6-11-48(43)50)67(104)91-56(33-59(76)96)65(102)84-38/h3-7,9-12,14-25,35-38,49,51-58,82,94-95H,8,13,26-34,75H2,1-2H3,(H2,76,96)(H2,77,98)(H,80,83)(H,84,102)(H,85,103)(H,86,99)(H,87,100)(H,88,105)(H,89,101)(H,90,106)(H,91,104)(H,92,107)(H,108,109)(H4,78,79,81)/t38-,49-,51-,52+,53-,54-,55-,56-,57-,58-,73?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-1 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50410398
(CHEMBL2096721)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C70H85N17O16/c1-37-59(93)81-50(30-39-13-6-4-7-14-39)65(99)80-49(19-12-28-76-69(74)75)62(96)84-52(33-43-36-77-48-18-11-10-17-46(43)48)66(100)85-53(34-56(72)90)63(97)78-38(2)60(94)82-51(31-40-15-8-5-9-16-40)67(101)86-70(3,68(102)103)87(55(58(73)92)32-42-22-26-45(89)27-23-42)57(91)35-54(64(98)79-37)83-61(95)47(71)29-41-20-24-44(88)25-21-41/h4-11,13-18,20-27,36-38,47,49-55,77,88-89H,12,19,28-35,71H2,1-3H3,(H2,72,90)(H2,73,92)(H,78,97)(H,79,98)(H,80,99)(H,81,93)(H,82,94)(H,83,95)(H,84,96)(H,85,100)(H,86,101)(H,102,103)(H4,74,75,76)/t37-,38-,47-,49-,50+,51-,52-,53-,54-,55-,70?/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.460 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-5 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50410405
(CHEMBL2096726)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C69H85N19O16/c1-36-58(94)81-48(27-37-10-4-3-5-11-37)64(100)86-69(2,67(103)104)88(54(57(72)93)28-39-18-22-43(90)23-19-39)56(92)32-51(82-59(95)45(70)26-38-16-20-42(89)21-17-38)63(99)85-52(30-41-34-75-35-78-41)66(102)87-25-9-15-53(87)65(101)80-47(14-8-24-76-68(73)74)60(96)83-49(29-40-33-77-46-13-7-6-12-44(40)46)62(98)84-50(31-55(71)91)61(97)79-36/h3-7,10-13,16-23,33-36,45,47-54,77,89-90H,8-9,14-15,24-32,70H2,1-2H3,(H2,71,91)(H2,72,93)(H,75,78)(H,79,97)(H,80,101)(H,81,94)(H,82,95)(H,83,96)(H,84,98)(H,85,99)(H,86,100)(H,103,104)(H4,73,74,76)/t36-,45-,47-,48-,49-,50-,51-,52-,53-,54-,69?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.03E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-1 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50410395
(CHEMBL2096731)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C73H87N17O16/c1-40-63(96)83-54(31-42-15-7-4-8-16-42)71(104)89-73(2,72(105)106)90(59(62(77)95)32-44-22-26-48(92)27-23-44)61(94)36-58(84-64(97)50(75)29-43-20-24-47(91)25-21-43)70(103)87-56(34-46-38-78-39-80-46)69(102)85-53(30-41-13-5-3-6-14-41)67(100)82-52(19-11-12-28-74)65(98)86-55(33-45-37-79-51-18-10-9-17-49(45)51)68(101)88-57(35-60(76)93)66(99)81-40/h3-10,13-18,20-27,37-40,50,52-59,79,91-92H,11-12,19,28-36,74-75H2,1-2H3,(H2,76,93)(H2,77,95)(H,78,80)(H,81,99)(H,82,100)(H,83,96)(H,84,97)(H,85,102)(H,86,98)(H,87,103)(H,88,101)(H,89,104)(H,105,106)/t40-,50-,52-,53+,54-,55-,56-,57-,58-,59-,73?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.08E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-3 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50410393
(CHEMBL2096819)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C73H87N19O16/c1-39-62(98)85-53(30-41-14-7-4-8-15-41)70(106)91-73(2,71(107)108)92(58(61(76)97)31-43-21-25-47(94)26-22-43)60(96)35-57(86-63(99)49(74)28-42-19-23-46(93)24-20-42)69(105)89-55(33-45-37-79-38-82-45)68(104)87-52(29-40-12-5-3-6-13-40)66(102)84-51(18-11-27-80-72(77)78)64(100)88-54(32-44-36-81-50-17-10-9-16-48(44)50)67(103)90-56(34-59(75)95)65(101)83-39/h3-10,12-17,19-26,36-39,49,51-58,81,93-94H,11,18,27-35,74H2,1-2H3,(H2,75,95)(H2,76,97)(H,79,82)(H,83,101)(H,84,102)(H,85,98)(H,86,99)(H,87,104)(H,88,100)(H,89,105)(H,90,103)(H,91,106)(H,107,108)(H4,77,78,80)/t39-,49-,51-,52+,53+,54-,55-,56-,57-,58-,73?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 14 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-3 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50410401
(CHEMBL2096729)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccc(cc2)-c2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C79H91N19O16/c1-43-68(104)91-59(33-44-12-5-3-6-13-44)76(112)97-79(2,77(113)114)98(64(67(82)103)35-47-23-29-53(100)30-24-47)66(102)39-63(92-69(105)55(80)32-45-21-27-52(99)28-22-45)75(111)95-61(37-51-41-85-42-88-51)74(110)93-58(34-46-19-25-49(26-20-46)48-14-7-4-8-15-48)72(108)90-57(18-11-31-86-78(83)84)70(106)94-60(36-50-40-87-56-17-10-9-16-54(50)56)73(109)96-62(38-65(81)101)71(107)89-43/h3-10,12-17,19-30,40-43,55,57-64,87,99-100H,11,18,31-39,80H2,1-2H3,(H2,81,101)(H2,82,103)(H,85,88)(H,89,107)(H,90,108)(H,91,104)(H,92,105)(H,93,110)(H,94,106)(H,95,111)(H,96,109)(H,97,112)(H,113,114)(H4,83,84,86)/t43-,55-,57-,58+,59-,60-,61-,62-,63-,64-,79?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 33 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-3 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50410407
(CHEMBL2096715)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)C2(CCc3ccccc3C2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C78H91N17O16/c1-43-66(101)88-58(36-45-16-7-4-8-17-45)72(107)93-77(2,75(110)111)95(62(65(81)100)37-47-25-29-52(97)30-26-47)64(99)40-61(89-67(102)54(79)34-46-23-27-51(96)28-24-46)73(108)94-78(32-31-48-18-9-10-19-49(48)41-78)74(109)92-57(35-44-14-5-3-6-15-44)70(105)87-56(22-13-33-84-76(82)83)68(103)90-59(38-50-42-85-55-21-12-11-20-53(50)55)71(106)91-60(39-63(80)98)69(104)86-43/h3-12,14-21,23-30,42-43,54,56-62,85,96-97H,13,22,31-41,79H2,1-2H3,(H2,80,98)(H2,81,100)(H,86,104)(H,87,105)(H,88,101)(H,89,102)(H,90,103)(H,91,106)(H,92,109)(H,93,107)(H,94,108)(H,110,111)(H4,82,83,84)/t43-,54-,56-,57+,58-,59-,60-,61-,62-,77?,78?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 690 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-1 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50410406
(CHEMBL2096723)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C70H80N16O16/c1-37-60(92)79-51(28-40-14-8-5-9-15-40)68(100)85-70(3,69(101)102)86(56(59(73)91)29-42-20-24-46(88)25-21-42)58(90)33-55(81-62(94)48(71)26-41-18-22-45(87)23-19-41)67(99)83-53(31-44-35-74-36-76-44)66(98)82-50(27-39-12-6-4-7-13-39)63(95)77-38(2)61(93)80-52(30-43-34-75-49-17-11-10-16-47(43)49)65(97)84-54(32-57(72)89)64(96)78-37/h4-25,34-38,48,50-56,75,87-88H,26-33,71H2,1-3H3,(H2,72,89)(H2,73,91)(H,74,76)(H,77,95)(H,78,96)(H,79,92)(H,80,93)(H,81,94)(H,82,98)(H,83,99)(H,84,97)(H,85,100)(H,101,102)/t37-,38-,48-,50+,51-,52-,53-,54-,55-,56-,70?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 66.5 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-1 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50410408
(CHEMBL2096713)Show SMILES C[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CC(=O)N([C@@H](Cc2ccc(O)cc2)C(N)=O)C(C)(NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C73H87N19O16/c1-39-62(98)85-53(30-41-14-7-4-8-15-41)70(106)91-73(2,71(107)108)92(58(61(76)97)31-43-21-25-47(94)26-22-43)60(96)35-57(86-63(99)49(74)28-42-19-23-46(93)24-20-42)69(105)89-55(33-45-37-79-38-82-45)68(104)87-52(29-40-12-5-3-6-13-40)66(102)84-51(18-11-27-80-72(77)78)64(100)88-54(32-44-36-81-50-17-10-9-16-48(44)50)67(103)90-56(34-59(75)95)65(101)83-39/h3-10,12-17,19-26,36-39,49,51-58,81,93-94H,11,18,27-35,74H2,1-2H3,(H2,75,95)(H2,76,97)(H,79,82)(H,83,101)(H,84,102)(H,85,98)(H,86,99)(H,87,104)(H,88,100)(H,89,105)(H,90,103)(H,91,106)(H,107,108)(H4,77,78,80)/t39-,49-,51-,52+,53-,54-,55-,56-,57-,58-,73?/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.370 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Effective concentration for mouse Melanocortin-5 receptor |
J Med Chem 48: 3060-75 (2005)
Article DOI: 10.1021/jm049010r
BindingDB Entry DOI: 10.7270/Q2PR7WS4 |
More data for this
Ligand-Target Pair | |
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