Affinity Data by PubMed id=15857114

PubMed code 15857114

Found 11 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50165956 ((S)-2-{2-[4-(4-Carbamimidoyl-benzyl)-3-oxo-3,4-dih...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	206	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibitory activity against binding of Fibrinogen to thrombocyte alpha IIb beta-3 integrin				J Med Chem 48: 3110-3 (2005) Article DOI: 10.1021/jm048984g BindingDB Entry DOI: 10.7270/Q2K0752H
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50165952 (2-Benzyl-N-[4-(4-carbamimidoyl-benzyl)-3-oxo-3,4-d...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	973	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibitory activity against binding of Fibrinogen to thrombocyte alpha IIb beta-3 integrin				J Med Chem 48: 3110-3 (2005) Article DOI: 10.1021/jm048984g BindingDB Entry DOI: 10.7270/Q2K0752H
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50165953 ((S)-3-{[2-(4-Carbamimidoyl-benzyloxy)-4-methyl-3-o...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.64E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibitory activity against binding of Fibrinogen to thrombocyte alpha IIb beta-3 integrin				J Med Chem 48: 3110-3 (2005) Article DOI: 10.1021/jm048984g BindingDB Entry DOI: 10.7270/Q2K0752H
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50165955 ((S)-2-{2-[4-(4-Carbamimidoyl-benzyl)-3-oxo-3,4-dih...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.66E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibitory activity against binding of Fibrinogen to thrombocyte alpha IIb beta-3 integrin				J Med Chem 48: 3110-3 (2005) Article DOI: 10.1021/jm048984g BindingDB Entry DOI: 10.7270/Q2K0752H
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50165954 ((S)-2-{(S)-2-[4-(4-Carbamimidoyl-benzyl)-3-oxo-3,4...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.94E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibitory activity against binding of Fibrinogen to thrombocyte alpha IIb beta-3 integrin				J Med Chem 48: 3110-3 (2005) Article DOI: 10.1021/jm048984g BindingDB Entry DOI: 10.7270/Q2K0752H
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50165957 (2-Benzyl-N-[4-(4-carbamimidoyl-benzyl)-3-oxo-3,4-d...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.94E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibitory activity against binding of Fibrinogen to thrombocyte alpha IIb beta-3 integrin				J Med Chem 48: 3110-3 (2005) Article DOI: 10.1021/jm048984g BindingDB Entry DOI: 10.7270/Q2K0752H
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50165959 ((R)-2-Benzyl-N-[4-(4-carbamimidoyl-benzyl)-3-oxo-3...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.19E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibitory activity against binding of Fibrinogen to thrombocyte alpha IIb beta-3 integrin				J Med Chem 48: 3110-3 (2005) Article DOI: 10.1021/jm048984g BindingDB Entry DOI: 10.7270/Q2K0752H
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50165960 (CHEMBL264985 \| {2-[4-(4-Carbamimidoyl-benzyl)-3-ox...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.84E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibitory activity against binding of Fibrinogen to thrombocyte alpha IIb beta-3 integrin				J Med Chem 48: 3110-3 (2005) Article DOI: 10.1021/jm048984g BindingDB Entry DOI: 10.7270/Q2K0752H
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50165962 ((S)-2-{2-[4-(4-Carbamimidoyl-benzyl)-3-oxo-3,4-dih...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibitory activity against binding of Fibrinogen to thrombocyte alpha IIb beta-3 integrin				J Med Chem 48: 3110-3 (2005) Article DOI: 10.1021/jm048984g BindingDB Entry DOI: 10.7270/Q2K0752H
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50165961 ((S)-3-{[2-(4-Carbamimidoyl-benzyloxy)-4-methyl-3-o...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.46E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibitory activity against binding of Fibrinogen to thrombocyte alpha IIb beta-3 integrin				J Med Chem 48: 3110-3 (2005) Article DOI: 10.1021/jm048984g BindingDB Entry DOI: 10.7270/Q2K0752H
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50165958 ((S)-2-{(S)-2-[4-(4-Carbamimidoyl-benzyl)-3-oxo-3,4...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.91E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibitory activity against binding of Fibrinogen to thrombocyte alpha IIb beta-3 integrin				J Med Chem 48: 3110-3 (2005) Article DOI: 10.1021/jm048984g BindingDB Entry DOI: 10.7270/Q2K0752H
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%