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PubMed code 15857137

Compile data set for download or QSAR
Found 10 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50166111
PNG
((E)-Octadec-9-enoic acid (R)-2-fluoro-3-phosphonoo...)
Show SMILES CCCCCCCC\C=C\CCCCCCCC(=O)OC[C@@H](F)COP(O)(O)=O
Show InChI InChI=1S/C21H40FO6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9+/t20-/m1/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells


J Med Chem 48: 3319-27 (2005)


Article DOI: 10.1021/jm049186t
BindingDB Entry DOI: 10.7270/Q2154GJ4
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50166119
PNG
(CHEMBL193406 | Hexadecanoic acid (S)-3,3-difluoro-...)
Show SMILES CCCCCCCCCCCCCCCC(=O)O[C@H](COP(O)(O)=O)CC(F)F
Show InChI InChI=1S/C20H39F2O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-20(23)28-18(16-19(21)22)17-27-29(24,25)26/h18-19H,2-17H2,1H3,(H2,24,25,26)/t18-/m0/s1
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The University of Utah

Curated by ChEMBL


Assay Description
Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells


J Med Chem 48: 3319-27 (2005)


Article DOI: 10.1021/jm049186t
BindingDB Entry DOI: 10.7270/Q2154GJ4
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50166120
PNG
(CHEMBL193196 | Hexadecanoic acid (S)-4-fluoro-2-me...)
Show SMILES CCCCCCCCCCCCCCCC(=O)OC[C@H](CC(F)P(O)(O)=O)OC
Show InChI InChI=1S/C21H42FO6P/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-21(23)28-18-19(27-2)17-20(22)29(24,25)26/h19-20H,3-18H2,1-2H3,(H2,24,25,26)/t19-,20?/m0/s1
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The University of Utah

Curated by ChEMBL


Assay Description
Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells


J Med Chem 48: 3319-27 (2005)


Article DOI: 10.1021/jm049186t
BindingDB Entry DOI: 10.7270/Q2154GJ4
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50166116
PNG
(CHEMBL191614 | Hexadecanoic acid (R)-4-fluoro-2-hy...)
Show SMILES CCCCCCCCCCCCCCCC(=O)OC[C@H](O)CC(F)P(O)(O)=O
Show InChI InChI=1S/C20H40FO6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-20(23)27-17-18(22)16-19(21)28(24,25)26/h18-19,22H,2-17H2,1H3,(H2,24,25,26)/t18-,19?/m1/s1
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The University of Utah

Curated by ChEMBL


Assay Description
Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells


J Med Chem 48: 3319-27 (2005)


Article DOI: 10.1021/jm049186t
BindingDB Entry DOI: 10.7270/Q2154GJ4
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50166117
PNG
(CHEMBL192452 | Hexadecanoic acid (S)-2-fluoro-3-ph...)
Show SMILES CCCCCCCCCCCCCCCC(=O)OC[C@H](F)COP(O)(O)=O
Show InChI InChI=1S/C19H38FO6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(21)25-16-18(20)17-26-27(22,23)24/h18H,2-17H2,1H3,(H2,22,23,24)/t18-/m0/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells


J Med Chem 48: 3319-27 (2005)


Article DOI: 10.1021/jm049186t
BindingDB Entry DOI: 10.7270/Q2154GJ4
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50166114
PNG
((E)-Octadec-9-enoic acid (S)-3,3-difluoro-1-phosph...)
Show SMILES CCCCCCCC\C=C\CCCCCCCC(=O)O[C@H](COP(O)(O)=O)CC(F)F
Show InChI InChI=1S/C22H41F2O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(25)30-20(18-21(23)24)19-29-31(26,27)28/h9-10,20-21H,2-8,11-19H2,1H3,(H2,26,27,28)/b10-9+/t20-/m0/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells


J Med Chem 48: 3319-27 (2005)


Article DOI: 10.1021/jm049186t
BindingDB Entry DOI: 10.7270/Q2154GJ4
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50166115
PNG
(CHEMBL190876 | PALMITOYL)
Show SMILES CCCCCCCCCCCCCCCC(=O)OCC(O)COP(O)([O-])=O
Show InChI InChI=1S/C19H39O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(21)25-16-18(20)17-26-27(22,23)24/h18,20H,2-17H2,1H3,(H2,22,23,24)/p-1
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n/an/an/an/a>1.00E+4n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells


J Med Chem 48: 3319-27 (2005)


Article DOI: 10.1021/jm049186t
BindingDB Entry DOI: 10.7270/Q2154GJ4
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50166118
PNG
(CHEMBL195383 | Hexadecanoic acid (R)-2,2-difluoro-...)
Show SMILES CCCCCCCCCCCCCCCC(=O)O[C@H](COP(O)(O)=O)C(F)F
Show InChI InChI=1S/C19H37F2O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(22)27-17(19(20)21)16-26-28(23,24)25/h17,19H,2-16H2,1H3,(H2,23,24,25)/t17-/m1/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells


J Med Chem 48: 3319-27 (2005)


Article DOI: 10.1021/jm049186t
BindingDB Entry DOI: 10.7270/Q2154GJ4
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50166113
PNG
(CHEMBL192210 | Hexadecanoic acid (R)-2-fluoro-3-ph...)
Show SMILES CCCCCCCCCCCCCCCC(=O)OC[C@@H](F)COP(O)(O)=O
Show InChI InChI=1S/C19H38FO6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(21)25-16-18(20)17-26-27(22,23)24/h18H,2-17H2,1H3,(H2,22,23,24)/t18-/m1/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells


J Med Chem 48: 3319-27 (2005)


Article DOI: 10.1021/jm049186t
BindingDB Entry DOI: 10.7270/Q2154GJ4
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50166112
PNG
((E)-Octadec-9-enoic acid (R)-2,2-difluoro-1-phosph...)
Show SMILES CCCCCCCC\C=C\CCCCCCCC(=O)O[C@H](COP(O)(O)=O)C(F)F
Show InChI InChI=1S/C21H39F2O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(24)29-19(21(22)23)18-28-30(25,26)27/h9-10,19,21H,2-8,11-18H2,1H3,(H2,25,26,27)/b10-9+/t19-/m1/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells


J Med Chem 48: 3319-27 (2005)


Article DOI: 10.1021/jm049186t
BindingDB Entry DOI: 10.7270/Q2154GJ4
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%