BindingDB logo
myBDB logout

PubMed code 15863301

Compile data set for download or QSAR
Found 53 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166407
PNG
((Z)-2-Benzoylamino-3-[4-(2-bromo-6-fluoro-phenoxy)...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(Oc2c(F)cccc2Br)cc1
Show InChI InChI=1S/C22H15BrFNO4/c23-17-7-4-8-18(24)20(17)29-16-11-9-14(10-12-16)13-19(22(27)28)25-21(26)15-5-2-1-3-6-15/h1-13H,(H,25,26)(H,27,28)/b19-13-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166360
PNG
((Z)-2-Benzoylamino-3-[4-(2-iodo-phenoxy)-phenyl]-a...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(Oc2ccccc2I)cc1
Show InChI InChI=1S/C22H16INO4/c23-18-8-4-5-9-20(18)28-17-12-10-15(11-13-17)14-19(22(26)27)24-21(25)16-6-2-1-3-7-16/h1-14H,(H,24,25)(H,26,27)/b19-14-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 40n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166374
PNG
((Z)-2-Benzoylamino-3-[4-(2-chloro-6-fluoro-phenoxy...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(Oc2c(F)cccc2Cl)cc1
Show InChI InChI=1S/C22H15ClFNO4/c23-17-7-4-8-18(24)20(17)29-16-11-9-14(10-12-16)13-19(22(27)28)25-21(26)15-5-2-1-3-6-15/h1-13H,(H,25,26)(H,27,28)/b19-13-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 70n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166405
PNG
((Z)-2-Benzoylamino-3-[4-(2-bromo-phenoxy)-phenyl]-...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(Oc2ccccc2Br)cc1
Show InChI InChI=1S/C22H16BrNO4/c23-18-8-4-5-9-20(18)28-17-12-10-15(11-13-17)14-19(22(26)27)24-21(25)16-6-2-1-3-7-16/h1-14H,(H,24,25)(H,26,27)/b19-14-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
Article
PubMed
n/an/a 100n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166379
PNG
((Z)-2-Benzoylamino-3-[4-(2-chloro-phenoxy)-phenyl]...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(Oc2ccccc2Cl)cc1
Show InChI InChI=1S/C22H16ClNO4/c23-18-8-4-5-9-20(18)28-17-12-10-15(11-13-17)14-19(22(26)27)24-21(25)16-6-2-1-3-7-16/h1-14H,(H,24,25)(H,26,27)/b19-14-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166369
PNG
((Z)-2-Benzoylamino-3-[4-(2-chloro-6-methyl-phenoxy...)
Show SMILES Cc1cccc(Cl)c1Oc1ccc(\C=C(/NC(=O)c2ccccc2)C(O)=O)cc1
Show InChI InChI=1S/C23H18ClNO4/c1-15-6-5-9-19(24)21(15)29-18-12-10-16(11-13-18)14-20(23(27)28)25-22(26)17-7-3-2-4-8-17/h2-14H,1H3,(H,25,26)(H,27,28)/b20-14-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166358
PNG
((2Z)-3-[4-(2-amino-6-chlorophenoxy)phenyl]-2-(phen...)
Show SMILES Nc1cccc(Cl)c1Oc1ccc(\C=C(/NC(=O)c2ccccc2)C(O)=O)cc1
Show InChI InChI=1S/C22H17ClN2O4/c23-17-7-4-8-18(24)20(17)29-16-11-9-14(10-12-16)13-19(22(27)28)25-21(26)15-5-2-1-3-6-15/h1-13H,24H2,(H,25,26)(H,27,28)/b19-13-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 310n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166376
PNG
((Z)-2-Benzoylamino-3-(4-o-tolyloxy-phenyl)-acrylic...)
Show SMILES Cc1ccccc1Oc1ccc(\C=C(/NC(=O)c2ccccc2)C(O)=O)cc1
Show InChI InChI=1S/C23H19NO4/c1-16-7-5-6-10-21(16)28-19-13-11-17(12-14-19)15-20(23(26)27)24-22(25)18-8-3-2-4-9-18/h2-15H,1H3,(H,24,25)(H,26,27)/b20-15-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 580n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166387
PNG
((Z)-2-Benzoylamino-3-[5-(2-chloro-phenyl)-thiophen...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(s1)-c1ccccc1Cl
Show InChI InChI=1S/C20H14ClNO3S/c21-16-9-5-4-8-15(16)18-11-10-14(26-18)12-17(20(24)25)22-19(23)13-6-2-1-3-7-13/h1-12H,(H,22,23)(H,24,25)/b17-12-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 660n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166397
PNG
((Z)-2-Benzoylamino-3-(2'-chloro-biphenyl-3-yl)-acr...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1cccc(c1)-c1ccccc1Cl
Show InChI InChI=1S/C22H16ClNO3/c23-19-12-5-4-11-18(19)17-10-6-7-15(13-17)14-20(22(26)27)24-21(25)16-8-2-1-3-9-16/h1-14H,(H,24,25)(H,26,27)/b20-14-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents
Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166384
PNG
((Z)-2-Benzoylamino-3-[4-(2-trifluoromethyl-phenoxy...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(Oc2ccccc2C(F)(F)F)cc1
Show InChI InChI=1S/C23H16F3NO4/c24-23(25,26)18-8-4-5-9-20(18)31-17-12-10-15(11-13-17)14-19(22(29)30)27-21(28)16-6-2-1-3-7-16/h1-14H,(H,27,28)(H,29,30)/b19-14-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166402
PNG
((Z)-2-Benzoylamino-3-[5-(2-chloro-phenyl)-furan-2-...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(o1)-c1ccccc1Cl
Show InChI InChI=1S/C20H14ClNO4/c21-16-9-5-4-8-15(16)18-11-10-14(26-18)12-17(20(24)25)22-19(23)13-6-2-1-3-7-13/h1-12H,(H,22,23)(H,24,25)/b17-12-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166367
PNG
((Z)-2-Benzoylamino-3-(5-o-tolyl-thiophen-2-yl)-acr...)
Show SMILES Cc1ccccc1-c1ccc(\C=C(/NC(=O)c2ccccc2)C(O)=O)s1
Show InChI InChI=1S/C21H17NO3S/c1-14-7-5-6-10-17(14)19-12-11-16(26-19)13-18(21(24)25)22-20(23)15-8-3-2-4-9-15/h2-13H,1H3,(H,22,23)(H,24,25)/b18-13-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166364
PNG
((Z)-2-Benzoylamino-3-(5-phenyl-thiophen-2-yl)-acry...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(s1)-c1ccccc1
Show InChI InChI=1S/C20H15NO3S/c22-19(15-9-5-2-6-10-15)21-17(20(23)24)13-16-11-12-18(25-16)14-7-3-1-4-8-14/h1-13H,(H,21,22)(H,23,24)/b17-13-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166371
PNG
((Z)-2-Benzoylamino-3-[4-(2-methylsulfanyl-phenoxy)...)
Show SMILES CSc1ccccc1Oc1ccc(\C=C(/NC(=O)c2ccccc2)C(O)=O)cc1
Show InChI InChI=1S/C23H19NO4S/c1-29-21-10-6-5-9-20(21)28-18-13-11-16(12-14-18)15-19(23(26)27)24-22(25)17-7-3-2-4-8-17/h2-15H,1H3,(H,24,25)(H,26,27)/b19-15-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.80E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166392
PNG
((Z)-2-Benzoylamino-3-[5-(2-fluoro-phenyl)-thiophen...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(s1)-c1ccccc1F
Show InChI InChI=1S/C20H14FNO3S/c21-16-9-5-4-8-15(16)18-11-10-14(26-18)12-17(20(24)25)22-19(23)13-6-2-1-3-7-13/h1-12H,(H,22,23)(H,24,25)/b17-12-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 2.60E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166378
PNG
((Z)-2-Benzoylamino-3-(5-o-tolyl-furan-2-yl)-acryli...)
Show SMILES Cc1ccccc1-c1ccc(\C=C(/NC(=O)c2ccccc2)C(O)=O)o1
Show InChI InChI=1S/C21H17NO4/c1-14-7-5-6-10-17(14)19-12-11-16(26-19)13-18(21(24)25)22-20(23)15-8-3-2-4-9-15/h2-13H,1H3,(H,22,23)(H,24,25)/b18-13-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166377
PNG
((Z)-2-Benzoylamino-3-[5-(2-fluoro-phenyl)-furan-2-...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(o1)-c1ccccc1F
Show InChI InChI=1S/C20H14FNO4/c21-16-9-5-4-8-15(16)18-11-10-14(26-18)12-17(20(24)25)22-19(23)13-6-2-1-3-7-13/h1-12H,(H,22,23)(H,24,25)/b17-12-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 3.10E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166363
PNG
((Z)-2-Benzoylamino-3-[5-(3-fluoro-phenyl)-furan-2-...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(o1)-c1cccc(F)c1
Show InChI InChI=1S/C20H14FNO4/c21-15-8-4-7-14(11-15)18-10-9-16(26-18)12-17(20(24)25)22-19(23)13-5-2-1-3-6-13/h1-12H,(H,22,23)(H,24,25)/b17-12-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 3.90E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166382
PNG
((Z)-2-Benzoylamino-3-[5-(2-trifluoromethoxy-phenyl...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(o1)-c1ccccc1OC(F)(F)F
Show InChI InChI=1S/C21H14F3NO5/c22-21(23,24)30-18-9-5-4-8-15(18)17-11-10-14(29-17)12-16(20(27)28)25-19(26)13-6-2-1-3-7-13/h1-12H,(H,25,26)(H,27,28)/b16-12-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 4.00E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166393
PNG
((Z)-2-Benzoylamino-3-[5-(4-chloro-phenyl)-furan-2-...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(o1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C20H14ClNO4/c21-15-8-6-13(7-9-15)18-11-10-16(26-18)12-17(20(24)25)22-19(23)14-4-2-1-3-5-14/h1-12H,(H,22,23)(H,24,25)/b17-12-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 4.60E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166403
PNG
((Z)-2-Benzoylamino-3-[5-(2-chloro-phenyl)-thiazol-...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ncc(s1)-c1ccccc1Cl
Show InChI InChI=1S/C19H13ClN2O3S/c20-14-9-5-4-8-13(14)16-11-21-17(26-16)10-15(19(24)25)22-18(23)12-6-2-1-3-7-12/h1-11H,(H,22,23)(H,24,25)/b15-10-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents
Article
PubMed
n/an/a 5.20E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166357
PNG
((Z)-2-Benzoylamino-3-[4-(2-chloro-6-nitro-phenoxy)...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(Oc2c(Cl)cccc2[N+]([O-])=O)cc1
Show InChI InChI=1S/C22H15ClN2O6/c23-17-7-4-8-19(25(29)30)20(17)31-16-11-9-14(10-12-16)13-18(22(27)28)24-21(26)15-5-2-1-3-6-15/h1-13H,(H,24,26)(H,27,28)/b18-13-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 5.50E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166386
PNG
((Z)-2-Benzoylamino-3-[5-(2-trifluoromethyl-phenyl)...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(o1)-c1ccccc1C(F)(F)F
Show InChI InChI=1S/C21H14F3NO4/c22-21(23,24)16-9-5-4-8-15(16)18-11-10-14(29-18)12-17(20(27)28)25-19(26)13-6-2-1-3-7-13/h1-12H,(H,25,26)(H,27,28)/b17-12-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 5.60E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166406
PNG
((Z)-2-Benzoylamino-3-[5-(3-chloro-phenyl)-furan-2-...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(o1)-c1cccc(Cl)c1
Show InChI InChI=1S/C20H14ClNO4/c21-15-8-4-7-14(11-15)18-10-9-16(26-18)12-17(20(24)25)22-19(23)13-5-2-1-3-6-13/h1-12H,(H,22,23)(H,24,25)/b17-12-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 6.00E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166389
PNG
((Z)-2-Benzoylamino-3-(5-phenyl-furan-2-yl)-acrylic...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(o1)-c1ccccc1
Show InChI InChI=1S/C20H15NO4/c22-19(15-9-5-2-6-10-15)21-17(20(23)24)13-16-11-12-18(25-16)14-7-3-1-4-8-14/h1-13H,(H,21,22)(H,23,24)/b17-13-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 6.70E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166385
PNG
((Z)-2-Benzoylamino-3-[4-(2-fluoro-phenoxy)-phenyl]...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(Oc2ccccc2F)cc1
Show InChI InChI=1S/C22H16FNO4/c23-18-8-4-5-9-20(18)28-17-12-10-15(11-13-17)14-19(22(26)27)24-21(25)16-6-2-1-3-7-16/h1-14H,(H,24,25)(H,26,27)/b19-14-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 6.90E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166388
PNG
((Z)-2-Benzoylamino-3-[5-(2-nitro-phenyl)-furan-2-y...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(o1)-c1ccccc1[N+]([O-])=O
Show InChI InChI=1S/C20H14N2O6/c23-19(13-6-2-1-3-7-13)21-16(20(24)25)12-14-10-11-18(28-14)15-8-4-5-9-17(15)22(26)27/h1-12H,(H,21,23)(H,24,25)/b16-12-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 6.90E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166401
PNG
((Z)-2-Benzoylamino-3-[5-(3-trifluoromethyl-phenyl)...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(o1)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C21H14F3NO4/c22-21(23,24)15-8-4-7-14(11-15)18-10-9-16(29-18)12-17(20(27)28)25-19(26)13-5-2-1-3-6-13/h1-12H,(H,25,26)(H,27,28)/b17-12-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 8.70E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166383
PNG
((Z)-2-Benzoylamino-3-[4-(2-ethyl-phenoxy)-phenyl]-...)
Show SMILES CCc1ccccc1Oc1ccc(\C=C(/NC(=O)c2ccccc2)C(O)=O)cc1
Show InChI InChI=1S/C24H21NO4/c1-2-18-8-6-7-11-22(18)29-20-14-12-17(13-15-20)16-21(24(27)28)25-23(26)19-9-4-3-5-10-19/h3-16H,2H2,1H3,(H,25,26)(H,27,28)/b21-16-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 9.40E+3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166356
PNG
((Z)-2-Benzoylamino-3-[6-(2-chloro-phenyl)-pyridin-...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1cccc(n1)-c1ccccc1Cl
Show InChI InChI=1S/C21H15ClN2O3/c22-17-11-5-4-10-16(17)18-12-6-9-15(23-18)13-19(21(26)27)24-20(25)14-7-2-1-3-8-14/h1-13H,(H,24,25)(H,26,27)/b19-13-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents
Article
PubMed
n/an/a 1.10E+4n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166396
PNG
((Z)-2-Benzoylamino-3-[5-(4-fluoro-phenyl)-furan-2-...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(o1)-c1ccc(F)cc1
Show InChI InChI=1S/C20H14FNO4/c21-15-8-6-13(7-9-15)18-11-10-16(26-18)12-17(20(24)25)22-19(23)14-4-2-1-3-5-14/h1-12H,(H,22,23)(H,24,25)/b17-12-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.20E+4n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166355
PNG
((Z)-2-Benzoylamino-3-[5-(4-trifluoromethyl-phenyl)...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(o1)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C21H14F3NO4/c22-21(23,24)15-8-6-13(7-9-15)18-11-10-16(29-18)12-17(20(27)28)25-19(26)14-4-2-1-3-5-14/h1-12H,(H,25,26)(H,27,28)/b17-12-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.30E+4n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166372
PNG
((Z)-2-Benzoylamino-3-[4-(2-methoxy-phenoxy)-phenyl...)
Show SMILES COc1ccccc1Oc1ccc(\C=C(/NC(=O)c2ccccc2)C(O)=O)cc1
Show InChI InChI=1S/C23H19NO5/c1-28-20-9-5-6-10-21(20)29-18-13-11-16(12-14-18)15-19(23(26)27)24-22(25)17-7-3-2-4-8-17/h2-15H,1H3,(H,24,25)(H,26,27)/b19-15-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.50E+4n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166395
PNG
((Z)-2-Benzoylamino-3-(4-phenoxy-phenyl)-acrylic ac...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C22H17NO4/c24-21(17-7-3-1-4-8-17)23-20(22(25)26)15-16-11-13-19(14-12-16)27-18-9-5-2-6-10-18/h1-15H,(H,23,24)(H,25,26)/b20-15-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.70E+4n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166368
PNG
((Z)-2-Benzoylamino-3-[5-(2-methoxy-phenyl)-furan-2...)
Show SMILES COc1ccccc1-c1ccc(\C=C(/NC(=O)c2ccccc2)C(O)=O)o1
Show InChI InChI=1S/C21H17NO5/c1-26-18-10-6-5-9-16(18)19-12-11-15(27-19)13-17(21(24)25)22-20(23)14-7-3-2-4-8-14/h2-13H,1H3,(H,22,23)(H,24,25)/b17-13-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166404
PNG
((Z)-2-Benzoylamino-3-[5-(2-hydroxymethyl-phenyl)-t...)
Show SMILES OCc1ccccc1-c1ccc(\C=C(/NC(=O)c2ccccc2)C(O)=O)s1
Show InChI InChI=1S/C21H17NO4S/c23-13-15-8-4-5-9-17(15)19-11-10-16(27-19)12-18(21(25)26)22-20(24)14-6-2-1-3-7-14/h1-12,23H,13H2,(H,22,24)(H,25,26)/b18-12-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166398
PNG
((Z)-2-Benzoylamino-3-[5-(4-trifluoromethoxy-phenyl...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(o1)-c1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C21H14F3NO5/c22-21(23,24)30-15-8-6-13(7-9-15)18-11-10-16(29-18)12-17(20(27)28)25-19(26)14-4-2-1-3-5-14/h1-12H,(H,25,26)(H,27,28)/b17-12-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 2.20E+4n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166375
PNG
((Z)-2-Benzoylamino-3-[5-(3-nitro-phenyl)-furan-2-y...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(o1)-c1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C20H14N2O6/c23-19(13-5-2-1-3-6-13)21-17(20(24)25)12-16-9-10-18(28-16)14-7-4-8-15(11-14)22(26)27/h1-12H,(H,21,23)(H,24,25)/b17-12-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 2.50E+4n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166366
PNG
((Z)-2-Benzoylamino-3-[5-(4-methylsulfanyl-phenyl)-...)
Show SMILES CSc1ccc(cc1)-c1ccc(\C=C(/NC(=O)c2ccccc2)C(O)=O)o1
Show InChI InChI=1S/C21H17NO4S/c1-27-17-10-7-14(8-11-17)19-12-9-16(26-19)13-18(21(24)25)22-20(23)15-5-3-2-4-6-15/h2-13H,1H3,(H,22,23)(H,24,25)/b18-13-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 2.70E+4n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166361
PNG
((Z)-2-Benzoylamino-3-[4-(2-isopropyl-phenoxy)-phen...)
Show SMILES CC(C)c1ccccc1Oc1ccc(\C=C(/NC(=O)c2ccccc2)C(O)=O)cc1
Show InChI InChI=1S/C25H23NO4/c1-17(2)21-10-6-7-11-23(21)30-20-14-12-18(13-15-20)16-22(25(28)29)26-24(27)19-8-4-3-5-9-19/h3-17H,1-2H3,(H,26,27)(H,28,29)/b22-16-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 2.80E+4n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166362
PNG
((Z)-2-Benzoylamino-3-[4-(2-isopropoxy-phenoxy)-phe...)
Show SMILES CC(C)Oc1ccccc1Oc1ccc(\C=C(/NC(=O)c2ccccc2)C(O)=O)cc1
Show InChI InChI=1S/C25H23NO5/c1-17(2)30-22-10-6-7-11-23(22)31-20-14-12-18(13-15-20)16-21(25(28)29)26-24(27)19-8-4-3-5-9-19/h3-17H,1-2H3,(H,26,27)(H,28,29)/b21-16-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 4.40E+4n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166359
PNG
((Z)-2-Benzoylamino-3-[4-(2-cyano-phenoxy)-phenyl]-...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(Oc2ccccc2C#N)cc1
Show InChI InChI=1S/C23H16N2O4/c24-15-18-8-4-5-9-21(18)29-19-12-10-16(11-13-19)14-20(23(27)28)25-22(26)17-6-2-1-3-7-17/h1-14H,(H,25,26)(H,27,28)/b20-14-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 4.70E+4n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166370
PNG
((Z)-2-Benzoylamino-3-[4-(biphenyl-2-yloxy)-phenyl]...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(Oc2ccccc2-c2ccccc2)cc1
Show InChI InChI=1S/C28H21NO4/c30-27(22-11-5-2-6-12-22)29-25(28(31)32)19-20-15-17-23(18-16-20)33-26-14-8-7-13-24(26)21-9-3-1-4-10-21/h1-19H,(H,29,30)(H,31,32)/b25-19-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 4.80E+4n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166394
PNG
((Z)-2-Benzoylamino-3-[5-(3-trifluoromethoxy-phenyl...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(o1)-c1cccc(OC(F)(F)F)c1
Show InChI InChI=1S/C21H14F3NO5/c22-21(23,24)30-16-8-4-7-14(11-16)18-10-9-15(29-18)12-17(20(27)28)25-19(26)13-5-2-1-3-6-13/h1-12H,(H,25,26)(H,27,28)/b17-12-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 6.60E+4n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166365
PNG
((Z)-2-Benzoylamino-3-[4-(2-nitro-phenoxy)-phenyl]-...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(Oc2ccccc2[N+]([O-])=O)cc1
Show InChI InChI=1S/C22H16N2O6/c25-21(16-6-2-1-3-7-16)23-18(22(26)27)14-15-10-12-17(13-11-15)30-20-9-5-4-8-19(20)24(28)29/h1-14H,(H,23,25)(H,26,27)/b18-14-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 7.30E+4n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166381
PNG
((Z)-2-Benzoylamino-3-[5-(3-sulfamoyl-phenyl)-furan...)
Show SMILES NS(=O)(=O)c1cccc(c1)-c1ccc(\C=C(/NC(=O)c2ccccc2)C(O)=O)o1
Show InChI InChI=1S/C20H16N2O6S/c21-29(26,27)16-8-4-7-14(11-16)18-10-9-15(28-18)12-17(20(24)25)22-19(23)13-5-2-1-3-6-13/h1-12H,(H,22,23)(H,24,25)(H2,21,26,27)/b17-12-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166399
PNG
((Z)-2-Benzoylamino-3-[5-(4-nitro-phenyl)-furan-2-y...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1ccc(o1)-c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C20H14N2O6/c23-19(14-4-2-1-3-5-14)21-17(20(24)25)12-16-10-11-18(28-16)13-6-8-15(9-7-13)22(26)27/h1-12H,(H,21,23)(H,24,25)/b17-12-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166391
PNG
((Z)-2-Benzoylamino-3-[4-(2-tert-butyl-phenoxy)-phe...)
Show SMILES CC(C)(C)c1ccccc1Oc1ccc(\C=C(/NC(=O)c2ccccc2)C(O)=O)cc1
Show InChI InChI=1S/C26H25NO4/c1-26(2,3)21-11-7-8-12-23(21)31-20-15-13-18(14-16-20)17-22(25(29)30)27-24(28)19-9-5-4-6-10-19/h4-17H,1-3H3,(H,27,28)(H,29,30)/b22-17-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166400
PNG
((Z)-2-Benzoylamino-3-[5-(4-sulfamoyl-phenyl)-furan...)
Show SMILES NS(=O)(=O)c1ccc(cc1)-c1ccc(\C=C(/NC(=O)c2ccccc2)C(O)=O)o1
Show InChI InChI=1S/C20H16N2O6S/c21-29(26,27)16-9-6-13(7-10-16)18-11-8-15(28-18)12-17(20(24)25)22-19(23)14-4-2-1-3-5-14/h1-12H,(H,22,23)(H,24,25)(H2,21,26,27)/b17-12-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166390
PNG
((Z)-2-Benzoylamino-3-[5-(3-hydroxymethyl-phenyl)-f...)
Show SMILES OCc1cccc(c1)-c1ccc(\C=C(/NC(=O)c2ccccc2)C(O)=O)o1
Show InChI InChI=1S/C21H17NO5/c23-13-14-5-4-8-16(11-14)19-10-9-17(27-19)12-18(21(25)26)22-20(24)15-6-2-1-3-7-15/h1-12,23H,13H2,(H,22,24)(H,25,26)/b18-12-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166380
PNG
((Z)-2-Benzoylamino-3-[5-(4-hydroxymethyl-phenyl)-f...)
Show SMILES OCc1ccc(cc1)-c1ccc(\C=C(/NC(=O)c2ccccc2)C(O)=O)o1
Show InChI InChI=1S/C21H17NO5/c23-13-14-6-8-15(9-7-14)19-11-10-17(27-19)12-18(21(25)26)22-20(24)16-4-2-1-3-5-16/h1-12,23H,13H2,(H,22,24)(H,25,26)/b18-12-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50166373
PNG
((Z)-2-Benzoylamino-3-[5-(2-chloro-phenyl)-pyridin-...)
Show SMILES OC(=O)C(\NC(=O)c1ccccc1)=C\c1cncc(c1)-c1ccccc1Cl
Show InChI InChI=1S/C21H15ClN2O3/c22-18-9-5-4-8-17(18)16-10-14(12-23-13-16)11-19(21(26)27)24-20(25)15-6-2-1-3-7-15/h1-13H,(H,24,25)(H,26,27)/b19-11-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against Hepatitis C virus NS5B polymerase

Bioorg Med Chem Lett 15: 2481-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.066
BindingDB Entry DOI: 10.7270/Q2VH5NC7
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%