Affinity Data by PubMed id=15887967

PubMed code 15887967

Found 24 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50056272 ((1S,2S,5R,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dic...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 2				J Med Chem 48: 3605-12 (2005) Article DOI: 10.1021/jm040222y BindingDB Entry DOI: 10.7270/Q2NS0TDR
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50056272 ((1S,2S,5R,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dic...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 3				J Med Chem 48: 3605-12 (2005) Article DOI: 10.1021/jm040222y BindingDB Entry DOI: 10.7270/Q2NS0TDR
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50167033 ((1S,2S,3R,5R,6S)-2-Amino-3-methyl-bicyclo[3.1.0]he...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	146	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 3				J Med Chem 48: 3605-12 (2005) Article DOI: 10.1021/jm040222y BindingDB Entry DOI: 10.7270/Q2NS0TDR
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50167032 ((1S,2S,4R,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	409	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 2				J Med Chem 48: 3605-12 (2005) Article DOI: 10.1021/jm040222y BindingDB Entry DOI: 10.7270/Q2NS0TDR
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50167032 ((1S,2S,4R,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	409	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 2				J Med Chem 48: 3605-12 (2005) Article DOI: 10.1021/jm040222y BindingDB Entry DOI: 10.7270/Q2NS0TDR
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50167034 ((1S,2S,4S,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	511	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 3				J Med Chem 48: 3605-12 (2005) Article DOI: 10.1021/jm040222y BindingDB Entry DOI: 10.7270/Q2NS0TDR
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50167032 ((1S,2S,4R,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 3				J Med Chem 48: 3605-12 (2005) Article DOI: 10.1021/jm040222y BindingDB Entry DOI: 10.7270/Q2NS0TDR
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50167032 ((1S,2S,4R,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 3				J Med Chem 48: 3605-12 (2005) Article DOI: 10.1021/jm040222y BindingDB Entry DOI: 10.7270/Q2NS0TDR
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50167034 ((1S,2S,4S,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	635	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 2				J Med Chem 48: 3605-12 (2005) Article DOI: 10.1021/jm040222y BindingDB Entry DOI: 10.7270/Q2NS0TDR
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50167033 ((1S,2S,3R,5R,6S)-2-Amino-3-methyl-bicyclo[3.1.0]he...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	983	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 2				J Med Chem 48: 3605-12 (2005) Article DOI: 10.1021/jm040222y BindingDB Entry DOI: 10.7270/Q2NS0TDR
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50167031 ((1R,2R,4S,5S,6R)-2-Amino-4-methyl-bicyclo[3.1.0]he...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 2				J Med Chem 48: 3605-12 (2005) Article DOI: 10.1021/jm040222y BindingDB Entry DOI: 10.7270/Q2NS0TDR
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50167031 ((1R,2R,4S,5S,6R)-2-Amino-4-methyl-bicyclo[3.1.0]he...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 3				J Med Chem 48: 3605-12 (2005) Article DOI: 10.1021/jm040222y BindingDB Entry DOI: 10.7270/Q2NS0TDR
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50167033 ((1S,2S,3R,5R,6S)-2-Amino-3-methyl-bicyclo[3.1.0]he...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu2 receptor				J Med Chem 48: 3605-12 (2005) Article DOI: 10.1021/jm040222y BindingDB Entry DOI: 10.7270/Q2NS0TDR
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50167032 ((1S,2S,4R,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu3 receptor				J Med Chem 48: 3605-12 (2005) Article DOI: 10.1021/jm040222y BindingDB Entry DOI: 10.7270/Q2NS0TDR
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50167032 ((1S,2S,4R,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu3 receptor				J Med Chem 48: 3605-12 (2005) Article DOI: 10.1021/jm040222y BindingDB Entry DOI: 10.7270/Q2NS0TDR
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50167033 ((1S,2S,3R,5R,6S)-2-Amino-3-methyl-bicyclo[3.1.0]he...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu3 receptor				J Med Chem 48: 3605-12 (2005) Article DOI: 10.1021/jm040222y BindingDB Entry DOI: 10.7270/Q2NS0TDR
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50167031 ((1R,2R,4S,5S,6R)-2-Amino-4-methyl-bicyclo[3.1.0]he...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu3 receptor				J Med Chem 48: 3605-12 (2005) Article DOI: 10.1021/jm040222y BindingDB Entry DOI: 10.7270/Q2NS0TDR
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50167034 ((1S,2S,4S,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu2 receptor				J Med Chem 48: 3605-12 (2005) Article DOI: 10.1021/jm040222y BindingDB Entry DOI: 10.7270/Q2NS0TDR
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50167031 ((1R,2R,4S,5S,6R)-2-Amino-4-methyl-bicyclo[3.1.0]he...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu2 receptor				J Med Chem 48: 3605-12 (2005) Article DOI: 10.1021/jm040222y BindingDB Entry DOI: 10.7270/Q2NS0TDR
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50167034 ((1S,2S,4S,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	34	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu3 receptor				J Med Chem 48: 3605-12 (2005) Article DOI: 10.1021/jm040222y BindingDB Entry DOI: 10.7270/Q2NS0TDR
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50167032 ((1S,2S,4R,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	397	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu2 receptor				J Med Chem 48: 3605-12 (2005) Article DOI: 10.1021/jm040222y BindingDB Entry DOI: 10.7270/Q2NS0TDR
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50056272 ((1S,2S,5R,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dic...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	38	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu3 receptor				J Med Chem 48: 3605-12 (2005) Article DOI: 10.1021/jm040222y BindingDB Entry DOI: 10.7270/Q2NS0TDR
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50167032 ((1S,2S,4R,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	397	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu2 receptor				J Med Chem 48: 3605-12 (2005) Article DOI: 10.1021/jm040222y BindingDB Entry DOI: 10.7270/Q2NS0TDR
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50056272 ((1S,2S,5R,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dic...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu2 receptor				J Med Chem 48: 3605-12 (2005) Article DOI: 10.1021/jm040222y BindingDB Entry DOI: 10.7270/Q2NS0TDR
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%