Affinity Data by PubMed id=15895683

PubMed code 15895683

Found 14 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86010 (Chalcone, 10) Show SMILES Oc1ccc(Cl)cc1C(=O)\C=C\c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	5.76E+4	-24.2	n/a	n/a	n/a	n/a	n/a	8.0	25
Quaid-i-Azam University					Assay Description In vitro lipoxygenase inhibition assay, lipoxygenase inhibiting activity was convenintly measured by slightly modifying the spectrometic method devel...				J Enzyme Inhib Med Chem 20: 41-7 (2005) Article DOI: 10.1080/14756360400015231 BindingDB Entry DOI: 10.7270/Q2FX781C
Quaid-i-Azam University					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86012 (Chalcone, 11) Show SMILES Oc1ccc(Cl)cc1C(=O)\C=C\c1ccc(Cl)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	7.17E+4	-23.7	n/a	n/a	n/a	n/a	n/a	8.0	25
Quaid-i-Azam University					Assay Description In vitro lipoxygenase inhibition assay, lipoxygenase inhibiting activity was convenintly measured by slightly modifying the spectrometic method devel...				J Enzyme Inhib Med Chem 20: 41-7 (2005) Article DOI: 10.1080/14756360400015231 BindingDB Entry DOI: 10.7270/Q2FX781C
Quaid-i-Azam University					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Equus caballus (Horse))	BDBM86002 ((E)-1-phenyl-3-(2-hydroxyphenyl)-2-propen-1-one (8...) Show SMILES Oc1ccccc1\C=C\C(=O)c1ccccc1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	8.0	25
Quaid-i-Azam University					Assay Description In vitro cholinesterase inhibition assay using electric-eel acetylcholinesterase, horse-serum butyrylcholinesterse. The IC50 values were calculated ...				J Enzyme Inhib Med Chem 20: 41-7 (2005) Article DOI: 10.1080/14756360400015231 BindingDB Entry DOI: 10.7270/Q2FX781C
Quaid-i-Azam University					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Equus caballus (Horse))	BDBM86006 (Chalcone, 5) Show SMILES COc1ccc(\C=C\C(=O)c2ccccc2)cc1OC Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.31E+4	n/a	n/a	n/a	n/a	8.0	25
Quaid-i-Azam University					Assay Description In vitro cholinesterase inhibition assay using electric-eel acetylcholinesterase, horse-serum butyrylcholinesterse. The IC50 values were calculated ...				J Enzyme Inhib Med Chem 20: 41-7 (2005) Article DOI: 10.1080/14756360400015231 BindingDB Entry DOI: 10.7270/Q2FX781C
Quaid-i-Azam University					More data for this Ligand-Target Pair
Acetylcholinesterase (Tetronarce californica (Pacific electric ray) (Tor...)	BDBM86009 (Chalcone, 9) Show SMILES COc1ccc(\C=C\C(=O)c2ccccc2O)cc1OC Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.82E+4	n/a	n/a	n/a	n/a	8.0	25
Quaid-i-Azam University					Assay Description In vitro cholinesterase inhibition assay using electric-eel acetylcholinesterase, horse-serum butyrylcholinesterse. The IC50 values were calculated ...				J Enzyme Inhib Med Chem 20: 41-7 (2005) Article DOI: 10.1080/14756360400015231 BindingDB Entry DOI: 10.7270/Q2FX781C
Quaid-i-Azam University					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Equus caballus (Horse))	BDBM86005 (Chalcone, 4) Show SMILES COc1ccc(\C=C\C(=O)c2ccccc2)cc1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	8.0	25
Quaid-i-Azam University					Assay Description In vitro cholinesterase inhibition assay using electric-eel acetylcholinesterase, horse-serum butyrylcholinesterse. The IC50 values were calculated ...				J Enzyme Inhib Med Chem 20: 41-7 (2005) Article DOI: 10.1080/14756360400015231 BindingDB Entry DOI: 10.7270/Q2FX781C
Quaid-i-Azam University					More data for this Ligand-Target Pair
Acetylcholinesterase (Tetronarce californica (Pacific electric ray) (Tor...)	BDBM86010 (Chalcone, 10) Show SMILES Oc1ccc(Cl)cc1C(=O)\C=C\c1ccccc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.92E+4	n/a	n/a	n/a	n/a	8.0	25
Quaid-i-Azam University					Assay Description In vitro cholinesterase inhibition assay using electric-eel acetylcholinesterase, horse-serum butyrylcholinesterse. The IC50 values were calculated ...				J Enzyme Inhib Med Chem 20: 41-7 (2005) Article DOI: 10.1080/14756360400015231 BindingDB Entry DOI: 10.7270/Q2FX781C
Quaid-i-Azam University					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Equus caballus (Horse))	BDBM86004 (Chalcone 2 \| Chalcone, 3) Show SMILES Oc1ccc(\C=C\C(=O)c2ccccc2)cc1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	8.0	25
Quaid-i-Azam University					Assay Description In vitro cholinesterase inhibition assay using electric-eel acetylcholinesterase, horse-serum butyrylcholinesterse. The IC50 values were calculated ...				J Enzyme Inhib Med Chem 20: 41-7 (2005) Article DOI: 10.1080/14756360400015231 BindingDB Entry DOI: 10.7270/Q2FX781C
Quaid-i-Azam University					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Equus caballus (Horse))	BDBM86003 (Chalcone, 2) Show SMILES Oc1cccc(\C=C\C(=O)c2ccccc2)c1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.62E+4	n/a	n/a	n/a	n/a	8.0	25
Quaid-i-Azam University					Assay Description In vitro cholinesterase inhibition assay using electric-eel acetylcholinesterase, horse-serum butyrylcholinesterse. The IC50 values were calculated ...				J Enzyme Inhib Med Chem 20: 41-7 (2005) Article DOI: 10.1080/14756360400015231 BindingDB Entry DOI: 10.7270/Q2FX781C
Quaid-i-Azam University					More data for this Ligand-Target Pair
Acetylcholinesterase (Tetronarce californica (Pacific electric ray) (Tor...)	BDBM86007 (Chalcone, 6) Show SMILES Oc1ccccc1C(=O)\C=C\c1ccccc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.92E+4	n/a	n/a	n/a	n/a	8.0	25
Quaid-i-Azam University					Assay Description In vitro cholinesterase inhibition assay using electric-eel acetylcholinesterase, horse-serum butyrylcholinesterse. The IC50 values were calculated ...				J Enzyme Inhib Med Chem 20: 41-7 (2005) Article DOI: 10.1080/14756360400015231 BindingDB Entry DOI: 10.7270/Q2FX781C
Quaid-i-Azam University					More data for this Ligand-Target Pair
Acetylcholinesterase (Tetronarce californica (Pacific electric ray) (Tor...)	BDBM86008 (Chalcone, 7) Show SMILES COc1cccc(\C=C\C(=O)c2ccccc2O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.60E+4	n/a	n/a	n/a	n/a	8.0	25
Quaid-i-Azam University					Assay Description In vitro cholinesterase inhibition assay using electric-eel acetylcholinesterase, horse-serum butyrylcholinesterse. The IC50 values were calculated ...				J Enzyme Inhib Med Chem 20: 41-7 (2005) Article DOI: 10.1080/14756360400015231 BindingDB Entry DOI: 10.7270/Q2FX781C
Quaid-i-Azam University					More data for this Ligand-Target Pair
Acetylcholinesterase (Tetronarce californica (Pacific electric ray) (Tor...)	BDBM76395 ((E)-1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-2-prop...) Show SMILES COc1ccc(\C=C\C(=O)c2ccccc2O)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.29E+4	n/a	n/a	n/a	n/a	8.0	25
Quaid-i-Azam University					Assay Description In vitro cholinesterase inhibition assay using electric-eel acetylcholinesterase, horse-serum butyrylcholinesterse. The IC50 values were calculated ...				J Enzyme Inhib Med Chem 20: 41-7 (2005) Article DOI: 10.1080/14756360400015231 BindingDB Entry DOI: 10.7270/Q2FX781C
Quaid-i-Azam University					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Equus caballus (Horse))	BDBM29143 (CHEMBL7976 \| Chalcone 1 \| Chalcone, 13 \| cid_63776...) Show SMILES O=C(\C=C\c1ccccc1)c1ccccc1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.09E+5	n/a	n/a	n/a	n/a	8.0	25
Quaid-i-Azam University					Assay Description In vitro cholinesterase inhibition assay using electric-eel acetylcholinesterase, horse-serum butyrylcholinesterse. The IC50 values were calculated ...				J Enzyme Inhib Med Chem 20: 41-7 (2005) Article DOI: 10.1080/14756360400015231 BindingDB Entry DOI: 10.7270/Q2FX781C
Quaid-i-Azam University					More data for this Ligand-Target Pair
Acetylcholinesterase (Tetronarce californica (Pacific electric ray) (Tor...)	BDBM86011 (Chalcone, 12) Show SMILES Cc1cccc(\C=C\C(=O)c2cc(Cl)ccc2O)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.35E+5	n/a	n/a	n/a	n/a	8.0	25
Quaid-i-Azam University					Assay Description In vitro cholinesterase inhibition assay using electric-eel acetylcholinesterase, horse-serum butyrylcholinesterse. The IC50 values were calculated ...				J Enzyme Inhib Med Chem 20: 41-7 (2005) Article DOI: 10.1080/14756360400015231 BindingDB Entry DOI: 10.7270/Q2FX781C
Quaid-i-Azam University					More data for this Ligand-Target Pair

* indicates data uncertainty>20%