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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Serine/threonine-protein kinase Chk1 (Homo sapiens (Human)) | BDBM14805 (3-(5,6-Diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylami...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet  | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Chk1 kinase activity was assayed in reaction buffer containing substrate peptide, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-33P] ATP.... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
| Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human)) | BDBM14805 (3-(5,6-Diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylami...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Human CDK1 kinase activity was assayed in reaction buffer containing substrate Histone H1, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase Chk1 (Homo sapiens (Human)) | BDBM14803 (2-(5,6-Diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylami...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | DrugBank MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Chk1 kinase activity was assayed in reaction buffer containing substrate peptide, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-33P] ATP.... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human)) | BDBM14804 (1-(5,6-Diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylami...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Human CDK1 kinase activity was assayed in reaction buffer containing substrate Histone H1, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human)) | BDBM14803 (2-(5,6-Diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylami...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | DrugBank MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Human CDK1 kinase activity was assayed in reaction buffer containing substrate Histone H1, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase Chk1 (Homo sapiens (Human)) | BDBM14804 (1-(5,6-Diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylami...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Chk1 kinase activity was assayed in reaction buffer containing substrate peptide, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-33P] ATP.... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Serine/threonine-protein kinase Chk1 (Homo sapiens (Human)) | BDBM14801 (2-({5,6-diphenylfuro[2,3-d]pyrimidin-4-yl}(methyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | DrugBank MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | n/a | n/a | 6.10E+3 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Chk1 kinase activity was assayed in reaction buffer containing substrate peptide, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-33P] ATP.... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Serine/threonine-protein kinase Chk1 (Homo sapiens (Human)) | BDBM14799 (2-[5,6-Bis-(4-methoxy-phenyl)-furo[2,3-d]pyrimidin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 1.54E+4 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Chk1 kinase activity was assayed in reaction buffer containing substrate peptide, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-33P] ATP.... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Serine/threonine-protein kinase Chk1 (Homo sapiens (Human)) | BDBM14800 (2-(5,6-Diphenyl-furo[2,3-d]pyrimidin-4-ylamino)-et...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 2.09E+4 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Chk1 kinase activity was assayed in reaction buffer containing substrate peptide, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-33P] ATP.... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Serine/threonine-protein kinase Chk1 (Homo sapiens (Human)) | BDBM14802 ((5,6-Diphenyl-furo[2,3-d]pyrimidin-4-ylamino)-acet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 2.29E+4 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Chk1 kinase activity was assayed in reaction buffer containing substrate peptide, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-33P] ATP.... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human)) | BDBM14799 (2-[5,6-Bis-(4-methoxy-phenyl)-furo[2,3-d]pyrimidin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.94E+4 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Human CDK1 kinase activity was assayed in reaction buffer containing substrate Histone H1, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase Chk1 (Homo sapiens (Human)) | BDBM14810 (2-(5,6-Diphenyl-furo[2,3-d]pyrimidin-4-ylamino)-2-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Chk1 kinase activity was assayed in reaction buffer containing substrate peptide, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-33P] ATP.... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase Chk1 (Homo sapiens (Human)) | BDBM14813 (2-({5,6-diphenylfuro[2,3-d]pyrimidin-4-yl}amino)pr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Chk1 kinase activity was assayed in reaction buffer containing substrate peptide, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-33P] ATP.... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase Chk1 (Homo sapiens (Human)) | BDBM14807 (3-(5,6-Diphenyl-furo[2,3-d]pyrimidin-4-ylamino)-pr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Chk1 kinase activity was assayed in reaction buffer containing substrate peptide, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-33P] ATP.... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase Chk1 (Homo sapiens (Human)) | BDBM14812 ((5,6-Diphenyl-furo[2,3-d]pyrimidin-4-yl)-(2-methox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Chk1 kinase activity was assayed in reaction buffer containing substrate peptide, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-33P] ATP.... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase Chk1 (Homo sapiens (Human)) | BDBM14811 (N-(2-aminoethyl)-5,6-diphenylfuro[2,3-d]pyrimidin-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Chk1 kinase activity was assayed in reaction buffer containing substrate peptide, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-33P] ATP.... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase Chk1 (Homo sapiens (Human)) | BDBM14808 (Benzyl-(5,6-diphenyl-furo[2,3-d]pyrimidin-4-yl)-am...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Chk1 kinase activity was assayed in reaction buffer containing substrate peptide, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-33P] ATP.... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase Chk1 (Homo sapiens (Human)) | BDBM14809 (N-(5,6-Diphenyl-furo[2,3-d]pyrimidin-4-yl)-benzami...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Chk1 kinase activity was assayed in reaction buffer containing substrate peptide, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-33P] ATP.... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine/threonine-protein kinase Chk1 (Homo sapiens (Human)) | BDBM14806 (5,6-Diphenyl-furo[2,3-d]pyrimidin-4 -ylamine | 5,6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Chk1 kinase activity was assayed in reaction buffer containing substrate peptide, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-33P] ATP.... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human)) | BDBM14801 (2-({5,6-diphenylfuro[2,3-d]pyrimidin-4-yl}(methyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | DrugBank MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.11E+5 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Human CDK1 kinase activity was assayed in reaction buffer containing substrate Histone H1, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-dependent protein kinase catalytic subunit alpha (Homo sapiens (Human)) | BDBM14800 (2-(5,6-Diphenyl-furo[2,3-d]pyrimidin-4-ylamino)-et...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Human PKA kinase activity was assayed in reaction buffer containing substrate Kemptide, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-33P... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human)) | BDBM14800 (2-(5,6-Diphenyl-furo[2,3-d]pyrimidin-4-ylamino)-et...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Human CDK1 kinase activity was assayed in reaction buffer containing substrate Histone H1, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-dependent protein kinase catalytic subunit alpha (Homo sapiens (Human)) | BDBM14799 (2-[5,6-Bis-(4-methoxy-phenyl)-furo[2,3-d]pyrimidin...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Human PKA kinase activity was assayed in reaction buffer containing substrate Kemptide, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-33P... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-dependent protein kinase catalytic subunit alpha (Homo sapiens (Human)) | BDBM14804 (1-(5,6-Diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylami...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Human PKA kinase activity was assayed in reaction buffer containing substrate Kemptide, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-33P... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-dependent protein kinase catalytic subunit alpha (Homo sapiens (Human)) | BDBM14803 (2-(5,6-Diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylami...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | DrugBank MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Human PKA kinase activity was assayed in reaction buffer containing substrate Kemptide, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-33P... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-dependent protein kinase catalytic subunit alpha (Homo sapiens (Human)) | BDBM14802 ((5,6-Diphenyl-furo[2,3-d]pyrimidin-4-ylamino)-acet...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Human PKA kinase activity was assayed in reaction buffer containing substrate Kemptide, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-33P... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-dependent protein kinase catalytic subunit alpha (Homo sapiens (Human)) | BDBM14801 (2-({5,6-diphenylfuro[2,3-d]pyrimidin-4-yl}(methyl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | DrugBank MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Human PKA kinase activity was assayed in reaction buffer containing substrate Kemptide, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-33P... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human)) | BDBM14802 ((5,6-Diphenyl-furo[2,3-d]pyrimidin-4-ylamino)-acet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Human CDK1 kinase activity was assayed in reaction buffer containing substrate Histone H1, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-dependent protein kinase catalytic subunit alpha (Homo sapiens (Human)) | BDBM14805 (3-(5,6-Diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylami...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Vernalis (R&D) Ltd | Assay Description Human PKA kinase activity was assayed in reaction buffer containing substrate Kemptide, enzyme, and inhibitor in the presence of 100uM ATP/[gamma-33P... | J Med Chem 48: 4332-45 (2005) Article DOI: 10.1021/jm049022c BindingDB Entry DOI: 10.7270/Q2WW7FXS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
