Affinity Data by PubMed id=15993060

PubMed code 15993060

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50169697 (CHEMBL182254 \| [3-Chloro-4-(3-fluoro-benzyloxy)-ph...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	7.5	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against EGFR by using [gamma-33P]-ATP as radioligand in pH 7.5				Bioorg Med Chem Lett 15: 3778-81 (2005) Article DOI: 10.1016/j.bmcl.2005.05.100 BindingDB Entry DOI: 10.7270/Q2P84BDM
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50169696 ((4-Benzyloxy-3-chloro-phenyl)-(1,3,8a,9-tetraaza-f...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	7.5	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against EGFR by using [gamma-33P]-ATP as radioligand in pH 7.5				Bioorg Med Chem Lett 15: 3778-81 (2005) Article DOI: 10.1016/j.bmcl.2005.05.100 BindingDB Entry DOI: 10.7270/Q2P84BDM
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50169697 (CHEMBL182254 \| [3-Chloro-4-(3-fluoro-benzyloxy)-ph...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>63	n/a	n/a	n/a	n/a	7.5	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against ErbB-2 protein tyrosine kinase by using [gamma-33P]-ATP as radioligand in pH 7.5				Bioorg Med Chem Lett 15: 3778-81 (2005) Article DOI: 10.1016/j.bmcl.2005.05.100 BindingDB Entry DOI: 10.7270/Q2P84BDM
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50169696 ((4-Benzyloxy-3-chloro-phenyl)-(1,3,8a,9-tetraaza-f...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	7.5	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against ErbB-2 protein tyrosine kinase by using [gamma-33P]-ATP as radioligand in pH 7.5				Bioorg Med Chem Lett 15: 3778-81 (2005) Article DOI: 10.1016/j.bmcl.2005.05.100 BindingDB Entry DOI: 10.7270/Q2P84BDM
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50169701 ((3-Chloro-4-fluoro-phenyl)-(1,3,8a,9-tetraaza-fluo...) Show SMILES Fc1ccc(Nc2ncnc3nn4ccccc4c23)cc1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	7.5	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against EGFR by using [gamma-33P]-ATP as radioligand in pH 7.5				Bioorg Med Chem Lett 15: 3778-81 (2005) Article DOI: 10.1016/j.bmcl.2005.05.100 BindingDB Entry DOI: 10.7270/Q2P84BDM
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50169699 ((2-Benzyl-1H-benzoimidazol-5-yl)-(1,3,8a,9-tetraaz...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	7.5	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against ErbB-2 protein tyrosine kinase by using [gamma-33P]-ATP as radioligand in pH 7.5				Bioorg Med Chem Lett 15: 3778-81 (2005) Article DOI: 10.1016/j.bmcl.2005.05.100 BindingDB Entry DOI: 10.7270/Q2P84BDM
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50169699 ((2-Benzyl-1H-benzoimidazol-5-yl)-(1,3,8a,9-tetraaz...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	7.5	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against EGFR by using [gamma-33P]-ATP as radioligand in pH 7.5				Bioorg Med Chem Lett 15: 3778-81 (2005) Article DOI: 10.1016/j.bmcl.2005.05.100 BindingDB Entry DOI: 10.7270/Q2P84BDM
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50169694 (1,3,8a,9-Tetraaza-fluoren-4-ylamine \| CHEMBL368891) Show SMILES Nc1ncnc2nn3ccccc3c12 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against ErbB-2 protein tyrosine kinase by using [gamma-33P]-ATP as radioligand in pH 7.5				Bioorg Med Chem Lett 15: 3778-81 (2005) Article DOI: 10.1016/j.bmcl.2005.05.100 BindingDB Entry DOI: 10.7270/Q2P84BDM
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50169701 ((3-Chloro-4-fluoro-phenyl)-(1,3,8a,9-tetraaza-fluo...) Show SMILES Fc1ccc(Nc2ncnc3nn4ccccc4c23)cc1Cl Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against ErbB-2 protein tyrosine kinase by using [gamma-33P]-ATP as radioligand in pH 7.5				Bioorg Med Chem Lett 15: 3778-81 (2005) Article DOI: 10.1016/j.bmcl.2005.05.100 BindingDB Entry DOI: 10.7270/Q2P84BDM
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50169694 (1,3,8a,9-Tetraaza-fluoren-4-ylamine \| CHEMBL368891) Show SMILES Nc1ncnc2nn3ccccc3c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory concentration against EGFR by using [gamma-33P]-ATP as radioligand in pH 7.5				Bioorg Med Chem Lett 15: 3778-81 (2005) Article DOI: 10.1016/j.bmcl.2005.05.100 BindingDB Entry DOI: 10.7270/Q2P84BDM
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%