Affinity Data by PubMed id=15999996

PubMed code 15999996

Found 3 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50169956 (2-(Benzooxazol-2-ylsulfanyl)-N-(4-tetrazol-1-yl-ph...) Show SMILES O=C(CSc1nc2ccccc2o1)Nc1ccc(cc1)-n1cnnn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Dissociation constant for ERK2 kinase				J Med Chem 48: 4586-95 (2005) Article DOI: 10.1021/jm0501174 BindingDB Entry DOI: 10.7270/Q2VT1RNN
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50169955 (3-(2-Amino-ethyl)-5-[1-(4-ethoxy-phenyl)-meth-(Z)-...) Show SMILES CCOc1ccc(\C=C2/SC(=O)N(CCN)C2=O)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Dissociation constant for ERK2 kinase				J Med Chem 48: 4586-95 (2005) Article DOI: 10.1021/jm0501174 BindingDB Entry DOI: 10.7270/Q2VT1RNN
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50169957 (CHEMBL190710 \| N-[4-(2,3-Dihydro-benzo[1,4]dioxin-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Dissociation constant for ERK2 kinase				J Med Chem 48: 4586-95 (2005) Article DOI: 10.1021/jm0501174 BindingDB Entry DOI: 10.7270/Q2VT1RNN
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%