Affinity Data by PubMed id=16033285

PubMed code 16033285

Found 24 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50170966 (10-hydroxy-3,4-dimethoxy-17-methyl-17-azatetracycl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H][DAMGO] from mu opioid receptor of rat brain membranes				J Med Chem 48: 5052-5 (2005) Article DOI: 10.1021/jm0580205 BindingDB Entry DOI: 10.7270/Q2P26ZW1
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50026682 (10-hydroxy-3,4-dimethoxy-17-methyl-(10S)-17-azatet...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H][DAMGO] from mu opioid receptor of rat brain membranes				J Med Chem 48: 5052-5 (2005) Article DOI: 10.1021/jm0580205 BindingDB Entry DOI: 10.7270/Q2P26ZW1
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50026687 (3-hydroxy-4,10-dimethoxy-17-methyl-(10S)-17-azatet...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4.65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H][DAMGO] from mu opioid receptor of rat brain membranes				J Med Chem 48: 5052-5 (2005) Article DOI: 10.1021/jm0580205 BindingDB Entry DOI: 10.7270/Q2P26ZW1
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50170964 (3-hydroxy-4,10-dimethoxy-17-methyl-17-azatetracycl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	5.38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H][DAMGO] from mu opioid receptor of rat brain membranes				J Med Chem 48: 5052-5 (2005) Article DOI: 10.1021/jm0580205 BindingDB Entry DOI: 10.7270/Q2P26ZW1
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50000092 ((-)-(etorphine) \| (-)-morphine \| (1S,5R,13R,14S)-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	6.55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor of rat brain membranes				J Med Chem 48: 5052-5 (2005) Article DOI: 10.1021/jm0580205 BindingDB Entry DOI: 10.7270/Q2P26ZW1
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50170962 (3,10-dihydroxy-4-methoxy-17-methyl-17-azatetracycl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	31.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H][DAMGO] from mu opioid receptor of rat brain membranes				J Med Chem 48: 5052-5 (2005) Article DOI: 10.1021/jm0580205 BindingDB Entry DOI: 10.7270/Q2P26ZW1
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50170963 (3,10-dihydroxy-4-methoxy-17-methyl-17-azatetracycl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	32.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H][DAMGO] from mu opioid receptor of rat brain membranes				J Med Chem 48: 5052-5 (2005) Article DOI: 10.1021/jm0580205 BindingDB Entry DOI: 10.7270/Q2P26ZW1
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50370595 (OXYCODONE \| Oxycontin \| US1184575, oxycodone \| US9...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	43.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor of rat brain membranes				J Med Chem 48: 5052-5 (2005) Article DOI: 10.1021/jm0580205 BindingDB Entry DOI: 10.7270/Q2P26ZW1
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50026682 (10-hydroxy-3,4-dimethoxy-17-methyl-(10S)-17-azatet...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	91.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H]Ile5,6]-deltorphin II from delta opioid receptor of rat brain membranes				J Med Chem 48: 5052-5 (2005) Article DOI: 10.1021/jm0580205 BindingDB Entry DOI: 10.7270/Q2P26ZW1
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50170966 (10-hydroxy-3,4-dimethoxy-17-methyl-17-azatetracycl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	107	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H]Ile5,6]-deltorphin II from delta opioid receptor of rat brain membranes				J Med Chem 48: 5052-5 (2005) Article DOI: 10.1021/jm0580205 BindingDB Entry DOI: 10.7270/Q2P26ZW1
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50000092 ((-)-(etorphine) \| (-)-morphine \| (1S,5R,13R,14S)-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	113	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from kappa opioid receptor of rat brain membranes				J Med Chem 48: 5052-5 (2005) Article DOI: 10.1021/jm0580205 BindingDB Entry DOI: 10.7270/Q2P26ZW1
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50026687 (3-hydroxy-4,10-dimethoxy-17-methyl-(10S)-17-azatet...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H]Ile5,6]-deltorphin II from delta opioid receptor of rat brain membranes				J Med Chem 48: 5052-5 (2005) Article DOI: 10.1021/jm0580205 BindingDB Entry DOI: 10.7270/Q2P26ZW1
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50170964 (3-hydroxy-4,10-dimethoxy-17-methyl-17-azatetracycl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	197	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H]Ile5,6]-deltorphin II from delta opioid receptor of rat brain membranes				J Med Chem 48: 5052-5 (2005) Article DOI: 10.1021/jm0580205 BindingDB Entry DOI: 10.7270/Q2P26ZW1
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50000092 ((-)-(etorphine) \| (-)-morphine \| (1S,5R,13R,14S)-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	217	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H[Ile5,6]-deltorphin II from delta opioid receptor of rat brain membranes				J Med Chem 48: 5052-5 (2005) Article DOI: 10.1021/jm0580205 BindingDB Entry DOI: 10.7270/Q2P26ZW1
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50170966 (10-hydroxy-3,4-dimethoxy-17-methyl-17-azatetracycl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	364	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of[3H]U69,593 from kappa opioid receptor of rat brain membranes				J Med Chem 48: 5052-5 (2005) Article DOI: 10.1021/jm0580205 BindingDB Entry DOI: 10.7270/Q2P26ZW1
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50170964 (3-hydroxy-4,10-dimethoxy-17-methyl-17-azatetracycl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	378	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of[3H]U69,593 from kappa opioid receptor of rat brain membranes				J Med Chem 48: 5052-5 (2005) Article DOI: 10.1021/jm0580205 BindingDB Entry DOI: 10.7270/Q2P26ZW1
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50170962 (3,10-dihydroxy-4-methoxy-17-methyl-17-azatetracycl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	498	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H]Ile5,6]-deltorphin II from delta opioid receptor of rat brain membranes				J Med Chem 48: 5052-5 (2005) Article DOI: 10.1021/jm0580205 BindingDB Entry DOI: 10.7270/Q2P26ZW1
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50026687 (3-hydroxy-4,10-dimethoxy-17-methyl-(10S)-17-azatet...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	592	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of[3H]U69,593 from kappa opioid receptor of rat brain membranes				J Med Chem 48: 5052-5 (2005) Article DOI: 10.1021/jm0580205 BindingDB Entry DOI: 10.7270/Q2P26ZW1
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50026682 (10-hydroxy-3,4-dimethoxy-17-methyl-(10S)-17-azatet...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	693	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of[3H]U69,593 from kappa opioid receptor of rat brain membranes				J Med Chem 48: 5052-5 (2005) Article DOI: 10.1021/jm0580205 BindingDB Entry DOI: 10.7270/Q2P26ZW1
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50170963 (3,10-dihydroxy-4-methoxy-17-methyl-17-azatetracycl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	763	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of[3H]U69,593 from kappa opioid receptor of rat brain membranes				J Med Chem 48: 5052-5 (2005) Article DOI: 10.1021/jm0580205 BindingDB Entry DOI: 10.7270/Q2P26ZW1
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50170963 (3,10-dihydroxy-4-methoxy-17-methyl-17-azatetracycl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	881	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H]Ile5,6]-deltorphin II from delta opioid receptor of rat brain membranes				J Med Chem 48: 5052-5 (2005) Article DOI: 10.1021/jm0580205 BindingDB Entry DOI: 10.7270/Q2P26ZW1
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50370595 (OXYCODONE \| Oxycontin \| US1184575, oxycodone \| US9...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H[Ile5,6]-deltorphin II from delta opioid receptor of rat brain membranes				J Med Chem 48: 5052-5 (2005) Article DOI: 10.1021/jm0580205 BindingDB Entry DOI: 10.7270/Q2P26ZW1
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50170962 (3,10-dihydroxy-4-methoxy-17-methyl-17-azatetracycl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.65E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of[3H]U69,593 from kappa opioid receptor of rat brain membranes				J Med Chem 48: 5052-5 (2005) Article DOI: 10.1021/jm0580205 BindingDB Entry DOI: 10.7270/Q2P26ZW1
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50370595 (OXYCODONE \| Oxycontin \| US1184575, oxycodone \| US9...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	2.66E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from kappa opioid receptor of rat brain membranes				J Med Chem 48: 5052-5 (2005) Article DOI: 10.1021/jm0580205 BindingDB Entry DOI: 10.7270/Q2P26ZW1
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%