Affinity Data by PubMed id=16039855

PubMed code 16039855

Found 30 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50161019 (3-Hydroxy-6-methyl-pyridine-2-carboxylic acid (6-m...) Show SMILES Cc1cccc(NC(=O)c2nc(C)ccc2O)n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171050 ((5-Ethoxy-[3,3']bipyridinyl-6-yl)-(6-methyl-pyridi...) Show SMILES CCOc1cc(cnc1Nc1cccc(C)n1)-c1cccnc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171075 ((5-Chloro-3-ethoxy-pyridin-2-yl)-(6-methyl-pyridin...) Show SMILES CCOc1cc(Cl)cnc1Nc1cccc(C)n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171065 (CHEMBL366242 \| [3-Ethoxy-5-(pyridin-3-yloxy)-pyrid...) Show SMILES CCOc1cc(Oc2cccnc2)cnc1Nc1cccc(C)n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171052 ((3-Ethoxy-5-pyrimidin-5-yl-pyridin-2-yl)-(6-methyl...) Show SMILES CCOc1cc(cnc1Nc1cccc(C)n1)-c1cncnc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171048 (2-[5-Ethoxy-6-(6-methyl-pyridin-2-ylamino)-pyridin...) Show SMILES CCOc1cc(cnc1Nc1cccc(C)n1)-c1ccccc1C#N Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171055 ((3-Ethoxy-pyridin-2-yl)-(6-methyl-pyridin-2-yl)-am...) Show SMILES CCOc1cccnc1Nc1cccc(C)n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171051 ((5-Ethoxy-4'-methyl-[3,3']bipyridinyl-6-yl)-(6-met...) Show SMILES CCOc1cc(cnc1Nc1cccc(C)n1)-c1cnccc1C Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171073 (5-Ethoxy-6-(6-methyl-pyridin-2-ylamino)-nicotinoni...) Show SMILES CCOc1cc(cnc1Nc1cccc(C)n1)C#N Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171061 ((5-Bromo-3-ethoxy-pyridin-2-yl)-(6-methyl-pyridin-...) Show SMILES CCOc1cc(Br)cnc1Nc1cccc(C)n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171056 (5'-Ethoxy-6'-(6-methyl-pyridin-2-ylamino)-[3,3']bi...) Show SMILES CCOc1cc(cnc1Nc1cccc(C)n1)-c1cccnc1C#N Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171071 ((3-Ethoxy-5-methyl-pyridin-2-yl)-(6-methyl-pyridin...) Show SMILES CCOc1cc(C)cnc1Nc1cccc(C)n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	119	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171057 (CHEMBL370784 \| [3-Ethoxy-5-(3-fluoro-phenyl)-pyrid...) Show SMILES CCOc1cc(cnc1Nc1cccc(C)n1)-c1cccc(F)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171067 ((3-Ethoxy-pyridin-2-yl)-pyridin-2-yl-amine \| CHEMB...) Show SMILES CCOc1cccnc1Nc1ccccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	138	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171062 ((5'-Ethoxy-[2,3']bipyridinyl-6'-yl)-(6-methyl-pyri...) Show SMILES CCOc1cc(cnc1Nc1cccc(C)n1)-c1ccccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	193	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171074 ((3-Ethoxy-5-isothiazol-3-yl-pyridin-2-yl)-(6-methy...) Show SMILES CCOc1cc(cnc1Nc1cccc(C)n1)-c1ccsn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	243	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171076 ((3-Ethoxy-5-phenyl-pyridin-2-yl)-(6-methyl-pyridin...) Show SMILES CCOc1cc(cnc1Nc1cccc(C)n1)-c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	267	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171049 ((6-Methyl-pyridin-2-yl)-(3-propyl-pyridin-2-yl)-am...) Show SMILES CCCc1cccnc1Nc1cccc(C)n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	394	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171068 ((3-Methoxy-pyridin-2-yl)-(6-methyl-pyridin-2-yl)-a...) Show SMILES COc1cccnc1Nc1cccc(C)n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	458	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171058 ((3-Ethoxy-pyrazin-2-yl)-(6-methyl-pyridin-2-yl)-am...) Show SMILES CCOc1nccnc1Nc1cccc(C)n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	497	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171059 ((3-Ethoxy-5-p-tolyl-pyridin-2-yl)-(6-methyl-pyridi...) Show SMILES CCOc1cc(cnc1Nc1cccc(C)n1)-c1ccc(C)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	513	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171069 ((3-Ethoxy-pyridin-2-yl)-(6-methoxy-pyridin-2-yl)-a...) Show SMILES CCOc1cccnc1Nc1cccc(OC)n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	556	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171064 ((6-Methyl-pyridin-2-yl)-(3-methylsulfanyl-pyridin-...) Show SMILES CSc1cccnc1Nc1cccc(C)n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171072 ((3-Benzyloxy-pyridin-2-yl)-(6-methyl-pyridin-2-yl)...) Show SMILES Cc1cccc(Nc2ncccc2OCc2ccccc2)n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171066 ((3-Isopropoxy-pyridin-2-yl)-(6-methyl-pyridin-2-yl...) Show SMILES CC(C)Oc1cccnc1Nc1cccc(C)n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171063 ((6-Methyl-pyridin-2-yl)-(3-propoxy-pyridin-2-yl)-a...) Show SMILES CCCOc1cccnc1Nc1cccc(C)n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171070 ((3-Ethoxy-pyridin-2-yl)-(6-trifluoromethyl-pyridin...) Show SMILES CCOc1cccnc1Nc1cccc(n1)C(F)(F)F Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171053 ((3-Ethoxy-4-methyl-pyridin-2-yl)-(6-methyl-pyridin...) Show SMILES CCOc1c(C)ccnc1Nc1cccc(C)n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171060 (CHEMBL198757 \| N3-Ethyl-N2-(6-methyl-pyridin-2...) Show SMILES CCNc1cccnc1Nc1cccc(C)n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50171054 (6-(3-Ethoxy-pyridin-2-ylamino)-pyridine-2-carboxyl...) Show SMILES CCOc1cccnc1Nc1cccc(n1)C(=O)OC Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro potency against calcium flux in Ltk cells expressing human recombinant metabotropic glutamate receptor 5 using fluorescence detection				Bioorg Med Chem Lett 15: 4350-3 (2005) Article DOI: 10.1016/j.bmcl.2005.06.059 BindingDB Entry DOI: 10.7270/Q2QZ29H0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%