Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human)) | BDBM50172493 ((13S)-3-hydroxy-16-(hydroxymethylene)-13-methyl-7,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath Curated by ChEMBL | Assay Description Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estrone | J Med Chem 48: 5749-70 (2005) Article DOI: 10.1021/jm050348a BindingDB Entry DOI: 10.7270/Q2QJ7J38 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human)) | BDBM50172503 ((S)-6a-Methyl-4b,5,6,6a,8,10,10a,10b,11,12-decahyd...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath Curated by ChEMBL | Assay Description Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estrone | J Med Chem 48: 5749-70 (2005) Article DOI: 10.1021/jm050348a BindingDB Entry DOI: 10.7270/Q2QJ7J38 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human)) | BDBM50172504 ((S)-2-Hydroxy-6a-methyl-4b,5,6,6a,8,10,10a,10b,11,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath Curated by ChEMBL | Assay Description Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estrone | J Med Chem 48: 5749-70 (2005) Article DOI: 10.1021/jm050348a BindingDB Entry DOI: 10.7270/Q2QJ7J38 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human)) | BDBM50366344 (CHEMBL1627450) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath Curated by ChEMBL | Assay Description Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estrone | J Med Chem 48: 5749-70 (2005) Article DOI: 10.1021/jm050348a BindingDB Entry DOI: 10.7270/Q2QJ7J38 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human)) | BDBM50172495 ((S)-8-(2-Methoxy-ethyl)-6a-methyl-4b,5,6,6a,8,10,1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 530 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath Curated by ChEMBL | Assay Description Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estrone | J Med Chem 48: 5749-70 (2005) Article DOI: 10.1021/jm050348a BindingDB Entry DOI: 10.7270/Q2QJ7J38 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human)) | BDBM50172499 (3-((S)-2-Hydroxy-6a-methyl-4b,6,6a,10,10a,10b,11,1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 730 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath Curated by ChEMBL | Assay Description Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estrone | J Med Chem 48: 5749-70 (2005) Article DOI: 10.1021/jm050348a BindingDB Entry DOI: 10.7270/Q2QJ7J38 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human)) | BDBM50172496 ((S)-2-Hydroxy-6a-methyl-4b,5,6,6a,8,10,10a,10b,11,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath Curated by ChEMBL | Assay Description Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estrone | J Med Chem 48: 5749-70 (2005) Article DOI: 10.1021/jm050348a BindingDB Entry DOI: 10.7270/Q2QJ7J38 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human)) | BDBM50172500 ((S)-2-Hydroxy-6a-methyl-4b,5,6,6a,8,10,10a,10b,11,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 880 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath Curated by ChEMBL | Assay Description Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estrone | J Med Chem 48: 5749-70 (2005) Article DOI: 10.1021/jm050348a BindingDB Entry DOI: 10.7270/Q2QJ7J38 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human)) | BDBM50172494 (((S)-2-Hydroxy-6a-methyl-4b,6,6a,10,10a,10b,11,12-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 920 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath Curated by ChEMBL | Assay Description Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estrone | J Med Chem 48: 5749-70 (2005) Article DOI: 10.1021/jm050348a BindingDB Entry DOI: 10.7270/Q2QJ7J38 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human)) | BDBM50172502 ((S)-9-Hydroxymethyl-6a-methyl-4b,5,6,6a,8,10,10a,1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 950 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath Curated by ChEMBL | Assay Description Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estrone | J Med Chem 48: 5749-70 (2005) Article DOI: 10.1021/jm050348a BindingDB Entry DOI: 10.7270/Q2QJ7J38 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human)) | BDBM50370664 (CHEMBL1627756) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath Curated by ChEMBL | Assay Description Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estrone | J Med Chem 48: 5749-70 (2005) Article DOI: 10.1021/jm050348a BindingDB Entry DOI: 10.7270/Q2QJ7J38 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human)) | BDBM50172491 ((S)-2-Hydroxy-6a-methyl-4b,5,6,6a,8,10,10a,10b,11,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath Curated by ChEMBL | Assay Description Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estrone | J Med Chem 48: 5749-70 (2005) Article DOI: 10.1021/jm050348a BindingDB Entry DOI: 10.7270/Q2QJ7J38 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human)) | BDBM50172497 ((S)-2-Hydroxy-6a-methyl-4b,5,6,6a,8,10,10a,10b,11,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath Curated by ChEMBL | Assay Description Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estrone | J Med Chem 48: 5749-70 (2005) Article DOI: 10.1021/jm050348a BindingDB Entry DOI: 10.7270/Q2QJ7J38 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human)) | BDBM50172501 ((S)-6a,8-Dimethyl-4b,5,6,6a,8,10,10a,10b,11,12-dec...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath Curated by ChEMBL | Assay Description Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estrone | J Med Chem 48: 5749-70 (2005) Article DOI: 10.1021/jm050348a BindingDB Entry DOI: 10.7270/Q2QJ7J38 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
17-beta-hydroxysteroid dehydrogenase type 1 (Homo sapiens (Human)) | BDBM50370663 (CHEMBL1627759) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath Curated by ChEMBL | Assay Description Inhibition of 17-beta-hydroxysteroid dehydrogenase type 1 expressed in T47D human breast cancer cells using 2 nM [3H]estrone | J Med Chem 48: 5749-70 (2005) Article DOI: 10.1021/jm050348a BindingDB Entry DOI: 10.7270/Q2QJ7J38 | |||||||||||
More data for this Ligand-Target Pair |